دورية أكاديمية
CHEMICAL CONSTITUENTS AND ANTIBACTERIAL ACTIVITY OF THREE TYPES OF AMAZONIAN Melipona spp. GEOPROPOLIS
| العنوان: | CHEMICAL CONSTITUENTS AND ANTIBACTERIAL ACTIVITY OF THREE TYPES OF AMAZONIAN Melipona spp. GEOPROPOLIS |
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| المؤلفون: | Darlan C. dos Santos, Jorge M. David, Oscar C. S. Neto, Brenda O. Lima, Regiane Yatsuda, Bruno O. Moreira, Lucas M. Marques, Richardson F. Frazão |
| المصدر: | Química Nova, Vol 47, Iss 2 (2024) |
| بيانات النشر: | Sociedade Brasileira de Química, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | Melipona spp, Amazonian geopropolis, 7-O-methylaromadendrin, lipid composition, triterpenes, Chemistry, QD1-999 |
| الوصف: | This work describes the first chemical study on the metabolic profile of three geopropolis samples from Melipona fulva, M. compressipes, and M. paraensis collected in the Amazonian region. The samples were submitted to solvent extractions. The silylated hexane extracts were submitted to GC-MS analysis and tentatively identified mainly the presence of triterpenes, steroids, fatty acids, and alcohols. The chemical profile of M. fulva of and M. compressipes geopropolis are similar. However, cholesterol, triacontanol, and palmitic acid are the main compounds in M. fulva; in M. compressipes, palmitic acid, linoleic acid, and oleic acid are predominant. The chemical profile of the M. paraensis sample is entirely different once more than 60% of the extract comprises lupenone and triacontanol. The CHCl3 soluble fraction of the MeOH extract of the M. paraensis geopropolis was submitted to chromatographic techniques, and it afforded cycloartenol, 24-methylene-cycloartenol, lupeol, α- and β-amirins, and 7-O-methylaromadendrin. The MeOH extract of this sample presents antimicrobial activities against strains of Streptococcus mutans, S. sobrinus, and S. aureus (MIC of 15.6-62.5 µg mL−1 and MBC of 62.5-1000 µg mL−1). The M. fulva and M. compressipes geopropolis were not active in this test. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Spanish; Castilian Portuguese |
| تدمد: | 1678-7064 0100-4042 |
| العلاقة: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422024000200202&tlng=enTest; https://doaj.org/toc/1678-7064Test |
| DOI: | 10.21577/0100-4042.20230096 |
| الوصول الحر: | https://doaj.org/article/00da36cb8ae341b2bd4c7843c66a9840Test |
| رقم الانضمام: | edsdoj.00da36cb8ae341b2bd4c7843c66a9840 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16787064 01004042 |
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| DOI: | 10.21577/0100-4042.20230096 |