المؤلفون: Yang, Xiaoxu, Xu, Xin, Breuss, Martin W, Antaki, Danny, Ball, Laurel L, Chung, Changuk, Shen, Jiawei, Li, Chen, George, Renee D, Wang, Yifan, Bae, Taejeong, Cheng, Yuhe, Abyzov, Alexej, Wei, Liping, Alexandrov, Ludmil B, Sebat, Jonathan L, Gleeson, Joseph G

المصدر: Nature Biotechnology. 41(6)

مصطلحات موضوعية: Genetics, Prevention, Brain Disorders, Human Genome, Underpinning research, 1.1 Normal biological development and functioning, Software, Whole Genome Sequencing, Exome Sequencing, Exome, High-Throughput Nucleotide Sequencing, Polymorphism, Single Nucleotide, Nucleotides, NIMH Brain Somatic Mosaicism Network

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/91f9r3tgTest

المؤلفون: Chung, Changuk, Yang, Xiaoxu, Bae, Taejeong, Vong, Keng Ioi, Mittal, Swapnil, Donkels, Catharina, Westley Phillips, H, Li, Zhen, Marsh, Ashley PL, Breuss, Martin W, Ball, Laurel L, Garcia, Camila Araújo Bernardino, George, Renee D, Gu, Jing, Xu, Mingchu, Barrows, Chelsea, James, Kiely N, Stanley, Valentina, Nidhiry, Anna S, Khoury, Sami, Howe, Gabrielle, Riley, Emily, Xu, Xin, Copeland, Brett, Wang, Yifan, Kim, Se Hoon, Kang, Hoon-Chul, Schulze-Bonhage, Andreas, Haas, Carola A, Urbach, Horst, Prinz, Marco, Limbrick, David D, Gurnett, Christina A, Smyth, Matthew D, Sattar, Shifteh, Nespeca, Mark, Gonda, David D, Imai, Katsumi, Takahashi, Yukitoshi, Chen, Hsin-Hung, Tsai, Jin-Wu, Conti, Valerio, Guerrini, Renzo, Devinsky, Orrin, Silva, Wilson A, Machado, Helio R, Mathern, Gary W, Abyzov, Alexej, Baldassari, Sara, Baulac, Stéphanie, Gleeson, Joseph G

المصدر: Nature Genetics. 55(2)

مصطلحات موضوعية: Genetics, Pediatric, Neurodegenerative, Epilepsy, Neurosciences, Human Genome, Brain Disorders, Biotechnology, Clinical Research, Stem Cell Research, Congenital Structural Anomalies, Underpinning research, 1.1 Normal biological development and functioning, Aetiology, 2.1 Biological and endogenous factors, Neurological, Humans, Multiomics, Brain, Mutation, Malformations of Cortical Development, Focal Cortical Dysplasia Neurogenetics Consortium, Brain Somatic Mosaicism Network, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6qk17474Test

المؤلفون: Bae, Taejeong, Fasching, Liana, Wang, Yifan, Shin, Joo Heon, Suvakov, Milovan, Jang, Yeongjun, Norton, Scott, Dias, Caroline, Mariani, Jessica, Jourdon, Alexandre, Wu, Feinan, Panda, Arijit, Pattni, Reenal, Chahine, Yasmine, Yeh, Rebecca, Roberts, Rosalinda C, Huttner, Anita, Kleinman, Joel E, Hyde, Thomas M, Straub, Richard E, Walsh, Christopher A, Urban, Alexander E, Leckman, James F, Weinberger, Daniel R, Vaccarino, Flora M, Abyzov, Alexej, Park, Peter J, Sestan, Nenad, Weinberger, Daniel, Moran, John V, Gage, Fred H, Gleeson, Joseph, Mathern, Gary, Courchesne, Eric, Roy, Subhojit, Chess, Andrew J, Akbarian, Schahram, Bizzotto, Sara, Coulter, Michael, D’Gama, Alissa, Ganz, Javier, Hill, Robert, Huang, August Yue, Khoshkhoo, Sattar, Kim, Sonia, Lee, Alice, Lodato, Michael, Maury, Eduardo A, Miller, Michael, Borges-Monroy, Rebeca, Rodin, Rachel, Zhou, Zinan, Bohrson, Craig, Chu, Chong, Cortes-Ciriano, Isidro, Dou, Yanmei, Galor, Alon, Gulhan, Doga, Kwon, Minseok, Luquette, Joe, Sherman, Maxwell, Viswanadham, Vinay, Jones, Attila, Rosenbluh, Chaggai, Cho, Sean, Langmead, Ben, Thorpe, Jeremy, Erwin, Jennifer, Jaffe, Andrew, McConnell, Michael, Narurkar, Rujuta, Paquola, Apua, Shin, Jooheon, Straub, Richard, Molitor, Cindy, Peters, Mette, Linker, Sara, Reed, Patrick, Wang, Meiyan, Urban, Alexander, Zhou, Bo, Zhu, Xiaowei, Serres Amero, Aitor, Juan, David, Lobon, Irene, Marques-Bonet, Tomas, Solis Moruno, Manuel, Garcia Perez, Raquel, Povolotskaya, Inna, Soriano, Eduardo, Antaki, Danny, Averbuj, Dan

المصدر: Science. 377(6605)

مصطلحات موضوعية: Biotechnology, Brain Disorders, Intellectual and Developmental Disabilities (IDD), Genetics, Autism, Pediatric, Mental Health, Human Genome, Underpinning research, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, Mental health, Aging, Autistic Disorder, Brain, Enhancer Elements, Genetic, Gene Expression Regulation, Humans, Mutagenesis, Mutation, Protein Binding, Transcription Factors, Whole Genome Sequencing, Brain Somatic Mosaicism Network§, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/17d0k7qwTest

المؤلفون: Breuss, Martin W, Yang, Xiaoxu, Schlachetzki, Johannes CM, Antaki, Danny, Lana, Addison J, Xu, Xin, Chung, Changuk, Chai, Guoliang, Stanley, Valentina, Song, Qiong, Newmeyer, Traci F, Nguyen, An, O’Brien, Sydney, Hoeksema, Marten A, Cao, Beibei, Nott, Alexi, McEvoy-Venneri, Jennifer, Pasillas, Martina P, Barton, Scott T, Copeland, Brett R, Nahas, Shareef, Van Der Kraan, Lucitia, Ding, Yan, Glass, Christopher K, Gleeson, Joseph G

المصدر: Nature. 604(7907)

مصطلحات موضوعية: Neurosciences, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research, Neurological, Cell Lineage, Cells, Cultured, Clone Cells, Humans, Microglia, Mosaicism, Neocortex, NIMH Brain Somatic Mosaicism Network, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4m11z022Test

المؤلفون: Wang, Yifan, Bae, Taejeong, Thorpe, Jeremy, Sherman, Maxwell A, Jones, Attila G, Cho, Sean, Daily, Kenneth, Dou, Yanmei, Ganz, Javier, Galor, Alon, Lobon, Irene, Pattni, Reenal, Rosenbluh, Chaggai, Tomasi, Simone, Tomasini, Livia, Yang, Xiaoxu, Zhou, Bo, Akbarian, Schahram, Ball, Laurel L, Bizzotto, Sara, Emery, Sarah B, Doan, Ryan, Fasching, Liana, Jang, Yeongjun, Juan, David, Lizano, Esther, Luquette, Lovelace J, Moldovan, John B, Narurkar, Rujuta, Oetjens, Matthew T, Rodin, Rachel E, Sekar, Shobana, Shin, Joo Heon, Soriano, Eduardo, Straub, Richard E, Zhou, Weichen, Chess, Andrew, Gleeson, Joseph G, Marquès-Bonet, Tomas, Park, Peter J, Peters, Mette A, Pevsner, Jonathan, Walsh, Christopher A, Weinberger, Daniel R, Vaccarino, Flora M, Moran, John V, Urban, Alexander E, Kidd, Jeffrey M, Mills, Ryan E, Abyzov, Alexej

المصدر: Genome Biology. 22(1)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Neurosciences, Human Genome, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Alleles, Brain, Chromosome Mapping, Computational Biology, Genetic Association Studies, Genetic Variation, Genomics, Germ Cells, High-Throughput Nucleotide Sequencing, Humans, Organ Specificity, Polymorphism, Single Nucleotide, Brain Somatic Mosaicism Network, Environmental Sciences, Information and Computing Sciences, Bioinformatics

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9hk3g68pTest

المؤلفون: Bizzotto, Sara, Dou, Yanmei, Ganz, Javier, Doan, Ryan N, Kwon, Minseok, Bohrson, Craig L, Kim, Sonia N, Bae, Taejeong, Abyzov, Alexej, Network†, NIMH Brain Somatic Mosaicism, Park, Peter J, Walsh, Christopher A

المصدر: Science. 371(6535)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Genetics, Human Genome, Pediatric, Biotechnology, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research, 2.1 Biological and endogenous factors, Aetiology, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Adolescent, Adult, Cell Division, Cell Lineage, Clone Cells, Embryonic Development, Female, Gastrula, Gastrulation, Genetic Variation, Germ Layers, Humans, Male, Mutation, Neural Stem Cells, Neurons, Organogenesis, Polymorphism, Single Nucleotide, Prosencephalon, Single-Cell Analysis, Whole Genome Sequencing, NIMH Brain Somatic Mosaicism Network, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9368w947Test

المؤلفون: Yifan Wang (380120), Taejeong Bae (9637278), Jeremy Thorpe (10494889), Maxwell A. Sherman (10494892), Attila G. Jones (10494895), Sean Cho (842114), Kenneth Daily (150164), Yanmei Dou (10494898), Javier Ganz (580190), Alon Galor (10494901), Irene Lobon (10494904), Reenal Pattni (10494907), Chaggai Rosenbluh (10494910), Simone Tomasi (139458), Livia Tomasini (10494913), Xiaoxu Yang (673521), Bo Zhou (15092), Schahram Akbarian (117762), Laurel L. Ball (10494916), Sara Bizzotto (10138543), Sarah B. Emery (3244203), Ryan Doan (572108), Liana Fasching (10494919), Yeongjun Jang (146006), David Juan (19252), Esther Lizano (5986972), Lovelace J. Luquette (10494922), John B. Moldovan (10494925), Rujuta Narurkar (10494928), Matthew T. Oetjens (9635214), Rachel E. Rodin (10138540), Shobana Sekar (4243036), Joo Heon Shin (7432022), Eduardo Soriano (196519), Richard E. Straub (10494931), Weichen Zhou (6004454), Andrew Chess (63935), Joseph G. Gleeson (10494934), Tomas Marquès-Bonet (10494937), Peter J. Park (8186340), Mette A. Peters (6641051), Jonathan Pevsner (15767), Christopher A. Walsh (8667276), Daniel R. Weinberger (9283256), Flora M. Vaccarino (10494940), John V. Moran (10494943), Alexander E. Urban (10494946), Jeffrey M. Kidd (7465493), Ryan E. Mills (10494949), Alexej Abyzov (9637287)

مصطلحات موضوعية: Genetics, mosaic SNVs, Brain Somatic Mosaicism Network, nucleotide variants, DNA repair, single-nucleotide variants, bulk DNA samples, brain regions, mosaic variants, Somatic mosaicism, non-cancerous tissues, brain tissue Abstract Background Po., variant allele fractions, Comprehensive identification, dural fibroblasts, dura mater, multi-institutional study, DNA replication, cell lineage trees, dorsolateral prefrontal cortex, whole-genome sequencing data

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Comprehensive_identification_of_somatic_nucleotide_variants_in_human_brain_tissue/14337760Test

الإتاحة: https://doi.org/10.6084/m9.figshare.14337760.v1Test

المؤلفون: Yifan Wang (380120), Taejeong Bae (9637278), Jeremy Thorpe (10494889), Maxwell A. Sherman (10494892), Attila G. Jones (10494895), Sean Cho (842114), Kenneth Daily (150164), Yanmei Dou (10494898), Javier Ganz (580190), Alon Galor (10494901), Irene Lobon (10494904), Reenal Pattni (10494907), Chaggai Rosenbluh (10494910), Simone Tomasi (139458), Livia Tomasini (10494913), Xiaoxu Yang (673521), Bo Zhou (15092), Schahram Akbarian (117762), Laurel L. Ball (10494916), Sara Bizzotto (10138543), Sarah B. Emery (3244203), Ryan Doan (572108), Liana Fasching (10494919), Yeongjun Jang (146006), David Juan (19252), Esther Lizano (5986972), Lovelace J. Luquette (10494922), John B. Moldovan (10494925), Rujuta Narurkar (10494928), Matthew T. Oetjens (9635214), Rachel E. Rodin (10138540), Shobana Sekar (4243036), Joo Heon Shin (7432022), Eduardo Soriano (196519), Richard E. Straub (10494931), Weichen Zhou (6004454), Andrew Chess (63935), Joseph G. Gleeson (10494934), Tomas Marquès-Bonet (10494937), Peter J. Park (8186340), Mette A. Peters (6641051), Jonathan Pevsner (15767), Christopher A. Walsh (8667276), Daniel R. Weinberger (9283256), Flora M. Vaccarino (10494940), John V. Moran (10494943), Alexander E. Urban (10494946), Jeffrey M. Kidd (7465493), Ryan E. Mills (10494949), Alexej Abyzov (9637287)

مصطلحات موضوعية: Genetics, mosaic SNVs, Brain Somatic Mosaicism Network, nucleotide variants, DNA repair, single-nucleotide variants, bulk DNA samples, brain regions, mosaic variants, Somatic mosaicism, non-cancerous tissues, brain tissue Abstract Background Po., variant allele fractions, Comprehensive identification, dural fibroblasts, dura mater, multi-institutional study, DNA replication, cell lineage trees, dorsolateral prefrontal cortex, whole-genome sequencing data

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_5_of_Comprehensive_identification_of_somatic_nucleotide_variants_in_human_brain_tissue/14337778Test

الإتاحة: https://doi.org/10.6084/m9.figshare.14337778.v1Test

المؤلفون: Yifan Wang (380120), Taejeong Bae (9637278), Jeremy Thorpe (10494889), Maxwell A. Sherman (10494892), Attila G. Jones (10494895), Sean Cho (842114), Kenneth Daily (150164), Yanmei Dou (10494898), Javier Ganz (580190), Alon Galor (10494901), Irene Lobon (10494904), Reenal Pattni (10494907), Chaggai Rosenbluh (10494910), Simone Tomasi (139458), Livia Tomasini (10494913), Xiaoxu Yang (673521), Bo Zhou (15092), Schahram Akbarian (117762), Laurel L. Ball (10494916), Sara Bizzotto (10138543), Sarah B. Emery (3244203), Ryan Doan (572108), Liana Fasching (10494919), Yeongjun Jang (146006), David Juan (19252), Esther Lizano (5986972), Lovelace J. Luquette (10494922), John B. Moldovan (10494925), Rujuta Narurkar (10494928), Matthew T. Oetjens (9635214), Rachel E. Rodin (10138540), Shobana Sekar (4243036), Joo Heon Shin (7432022), Eduardo Soriano (196519), Richard E. Straub (10494931), Weichen Zhou (6004454), Andrew Chess (63935), Joseph G. Gleeson (10494934), Tomas Marquès-Bonet (10494937), Peter J. Park (8186340), Mette A. Peters (6641051), Jonathan Pevsner (15767), Christopher A. Walsh (8667276), Daniel R. Weinberger (9283256), Flora M. Vaccarino (10494940), John V. Moran (10494943), Alexander E. Urban (10494946), Jeffrey M. Kidd (7465493), Ryan E. Mills (10494949), Alexej Abyzov (9637287)

مصطلحات موضوعية: Genetics, mosaic SNVs, Brain Somatic Mosaicism Network, nucleotide variants, DNA repair, single-nucleotide variants, bulk DNA samples, brain regions, mosaic variants, Somatic mosaicism, non-cancerous tissues, brain tissue Abstract Background Po., variant allele fractions, Comprehensive identification, dural fibroblasts, dura mater, multi-institutional study, DNA replication, cell lineage trees, dorsolateral prefrontal cortex, whole-genome sequencing data

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_6_of_Comprehensive_identification_of_somatic_nucleotide_variants_in_human_brain_tissue/14337781Test

الإتاحة: https://doi.org/10.6084/m9.figshare.14337781.v1Test

المؤلفون: Yifan Wang (380120), Taejeong Bae (9637278), Jeremy Thorpe (10494889), Maxwell A. Sherman (10494892), Attila G. Jones (10494895), Sean Cho (842114), Kenneth Daily (150164), Yanmei Dou (10494898), Javier Ganz (580190), Alon Galor (10494901), Irene Lobon (10494904), Reenal Pattni (10494907), Chaggai Rosenbluh (10494910), Simone Tomasi (139458), Livia Tomasini (10494913), Xiaoxu Yang (673521), Bo Zhou (15092), Schahram Akbarian (117762), Laurel L. Ball (10494916), Sara Bizzotto (10138543), Sarah B. Emery (3244203), Ryan Doan (572108), Liana Fasching (10494919), Yeongjun Jang (146006), David Juan (19252), Esther Lizano (5986972), Lovelace J. Luquette (10494922), John B. Moldovan (10494925), Rujuta Narurkar (10494928), Matthew T. Oetjens (9635214), Rachel E. Rodin (10138540), Shobana Sekar (4243036), Joo Heon Shin (7432022), Eduardo Soriano (196519), Richard E. Straub (10494931), Weichen Zhou (6004454), Andrew Chess (63935), Joseph G. Gleeson (10494934), Tomas Marquès-Bonet (10494937), Peter J. Park (8186340), Mette A. Peters (6641051), Jonathan Pevsner (15767), Christopher A. Walsh (8667276), Daniel R. Weinberger (9283256), Flora M. Vaccarino (10494940), John V. Moran (10494943), Alexander E. Urban (10494946), Jeffrey M. Kidd (7465493), Ryan E. Mills (10494949), Alexej Abyzov (9637287)

مصطلحات موضوعية: Genetics, mosaic SNVs, Brain Somatic Mosaicism Network, nucleotide variants, DNA repair, single-nucleotide variants, bulk DNA samples, brain regions, mosaic variants, Somatic mosaicism, non-cancerous tissues, brain tissue Abstract Background Po., variant allele fractions, Comprehensive identification, dural fibroblasts, dura mater, multi-institutional study, DNA replication, cell lineage trees, dorsolateral prefrontal cortex, whole-genome sequencing data

العلاقة: https://figshare.com/articles/dataset/Additional_file_3_of_Comprehensive_identification_of_somatic_nucleotide_variants_in_human_brain_tissue/14337769Test

الإتاحة: https://doi.org/10.6084/m9.figshare.14337769.v1Test