المؤلفون: Steven Mennerick, Yejun He, Xin Jiang, Brad D Manion, Mingde Wang, Amanda Shute, Ann Benz, Alex S Evers, Douglas F Covey, Charles F Zorumski

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://molpharm.aspetjournals.org/content/molpharm/65/5/1191.full.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1070.4509Test; http://molpharm.aspetjournals.org/content/molpharm/65/5/1191.full.pdfTest

الإتاحة: http://molpharm.aspetjournals.org/content/molpharm/65/5/1191.full.pdfTest

المؤلفون: Daniel J. Shin, Nicholas P. Franks, Christopher J. Edge, Brad D. Manion, Alex S. Evers, Edward H. Smith, Allison L. Germann, Gustav Akk

المصدر: British Journal of Pharmacology. 173:3110-3120

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, GABAA receptor, Chemistry, Long-term potentiation, GABAA-rho receptor, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine, Homomeric, GPR18, Receptor, Propofol, Glycine receptor, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::91553ba33fe53b4af55a39ab433833fdTest
https://doi.org/10.1111/bph.13566Test

المؤلفون: Gustav Akk, David E. Reichert, Allison L. Germann, Zi-Wei Chen, Wayland W.L. Cheng, John Bracamontes, Krishnan Kathiresan, Alex S. Evers, Douglas F. Covey, Daniel J. Shin, Mingxing Qian, Melissa M. Budelier, Brad D. Manion

المصدر: PLoS Biology, Vol 17, Iss 3, p e3000157 (2019)
PLoS Biology

مصطلحات موضوعية: 0301 basic medicine, Physiology, Xenopus, Cell Membranes, Biochemistry, Mass Spectrometry, Ion Channels, Xenopus laevis, 0302 clinical medicine, Medicine and Health Sciences, polycyclic compounds, Biology (General), Receptor, Neurotransmitter Agents, 0303 health sciences, Crystallography, Muscimol, Organic Compounds, Chemistry, GABAA receptor, Physics, General Neuroscience, Eukaryota, Neurochemistry, Neurotransmitters, Animal Models, Flow Cytometry, Condensed Matter Physics, Transmembrane protein, 3. Good health, Electrophysiology, Molecular Docking Simulation, Experimental Organism Systems, Physical Sciences, Xenopus Oocytes, Vertebrates, Crystal Structure, Frogs, Ligand-gated ion channel, Female, Steroids, Cellular Structures and Organelles, General Agricultural and Biological Sciences, hormones, hormone substitutes, and hormone antagonists, Research Article, medicine.drug, Neuroactive steroid, QH301-705.5, Pentamer, Biophysics, Neurophysiology, Biology, Research and Analysis Methods, General Biochemistry, Genetics and Molecular Biology, gamma-Aminobutyric acid, Cell Line, Amphibians, 03 medical and health sciences, Model Organisms, Receptors, GABA, mental disorders, medicine, Extracellular, Animals, Humans, Solid State Physics, Binding site, 030304 developmental biology, Binding Sites, General Immunology and Microbiology, Organic Chemistry, Chemical Compounds, Organisms, Membrane Proteins, Biology and Life Sciences, Proteins, Cell Biology, Gamma-Aminobutyric Acid, Ligand-Gated Ion Channels, 030104 developmental biology, nervous system, Docking (molecular), Oocytes, Animal Studies, 030217 neurology & neurosurgery, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7da0cae0a501e2d90451ea916de9f0Test
https://doi.org/10.1101/357574Test

المؤلفون: Alex S. Evers, Brad D. Manion, John Bracamontes, Ping Li, Joseph H. Steinbach, Gustav Akk, Steven Mennerick

المصدر: British Journal of Pharmacology. 171:5446-5457

مصطلحات موضوعية: Pharmacology, Pregnanolone, medicine.medical_specialty, Neuroactive steroid, Allosteric modulator, GABAA receptor, Chemistry, Allosteric regulation, Endocrinology, nervous system, Etomidate, Internal medicine, medicine, Receptor, Endogenous agonist, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::889b9808004a8fe432bf3173cc856b79Test
https://doi.org/10.1111/bph.12861Test

المؤلفون: Eva Kudova, George Elias, Alex S. Evers, Mingxing Qian, Charles F. Zorumski, Amanda Taylor, Brad D. Manion, Gustav Akk, Douglas F. Covey, Kathiresan Krishnan, Ping Li, Steven Mennerick

المصدر: Journal of Medicinal Chemistry. 57:171-190

مصطلحات موضوعية: Models, Molecular, Neuroactive steroid, Allosteric regulation, Pregnanolone, Pharmacology, Article, Pregnanediones, GABAA-rho receptor, Structure-Activity Relationship, Xenopus laevis, chemistry.chemical_compound, mental disorders, Drug Discovery, otorhinolaryngologic diseases, Animals, Humans, GABA Modulators, Neurotransmitter Agents, Chemistry, GABAA receptor, Allopregnanolone, Bridged Bicyclo Compounds, Heterocyclic, Receptors, GABA-A, Rats, HEK293 Cells, Molecular Medicine, Righting reflex

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620dd67df6ea8f77fc36215bb3b250e6Test
https://doi.org/10.1021/jm401577cTest

المؤلفون: Douglas F. Covey, Werner Sieghart, Zi-Wei Chen, Raymond R. Townsend, Brad D. Manion, David E. Reichert, Joe Henry Steinbach, Karoline Fuchs, Alex S. Evers

المصدر: Molecular Pharmacology. 82:408-419

مصطلحات موضوعية: Models, Molecular, Protein subunit, Aziridines, Immunoblotting, Molecular Sequence Data, Photoaffinity Labels, Pregnanolone, GABAA-rho receptor, Animals, Humans, Homomeric, Amino Acid Sequence, Binding site, Peptide sequence, Cells, Cultured, Pharmacology, Neurotransmitter Agents, Binding Sites, GABAA receptor, Chemistry, Brain, Articles, Receptors, GABA-A, Protein Structure, Tertiary, Rats, Protein Subunits, A-site, Transmembrane domain, Biochemistry, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531dd7ea5f8116c73949ba92ad4907f2Test
https://doi.org/10.1124/mol.112.078410Test

المؤلفون: Brad D. Manion, Amanda Taylor, Kyle Wu, Megan M. Eaton, Alex S. Evers, John Bracamontes, Steven Mennerick, Kathiresan Krishnan, Joe Henry Steinbach, Charles F. Zorumski, Hong-Jin Shu, Gustav Akk, Douglas F. Covey

المصدر: British Journal of Pharmacology. 165:2228-2243

مصطلحات موضوعية: Pharmacology, Agonist, Neuroactive steroid, GABAA receptor, medicine.drug_class, Class C GPCR, Biology, GABAA-rho receptor, Cell biology, medicine, Ligand-gated ion channel, Receptor, Cys-loop receptors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a441dc44fbf80766013321a8ee05270fTest
https://doi.org/10.1111/j.1476-5381.2011.01690.xTest

المؤلفون: Douglas F. Covey, Achintya K. Bandyopadhyaya, Nigam P. Rath, Steven Mennerick, Charles F. Zorumski, Amanda Taylor, Alex S. Evers, Brad D. Manion, Ann Benz

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:6680-6684

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Neuroactive steroid, Spectrophotometry, Infrared, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Crystallography, X-Ray, Biochemistry, Pregnanediones, Article, Steroid, Butyric acid, chemistry.chemical_compound, Nitriles, Drug Discovery, medicine, Animals, Receptor, Molecular Biology, gamma-Aminobutyric Acid, Anesthetics, Extramural, Organic Chemistry, Biological activity, Rats, chemistry, Anesthetic, Molecular Medicine, GABAergic, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cab7295b6399a46592b0069ee0b9b0Test
https://doi.org/10.1016/j.bmcl.2010.09.008Test

المؤلفون: Steven Mennerick, Kathiresan Krishnan, Achintya K. Bandyopadhyaya, Amanda Taylor, Cunde Wang, Douglas F. Covey, Hong-Jin Shu, Charles F. Zorumski, Alex S. Evers, Brad D. Manion, Ann Benz, Lawrence N. Eisenman

المصدر: Molecular Pharmacology. 76:754-765

مصطلحات موضوعية: Pharmacology, Patch-Clamp Techniques, Neuroactive steroid, Fluorophore, GABAA receptor, medicine.medical_treatment, Articles, Receptors, GABA-A, Rats, Steroid, Rhodamine, Xenopus laevis, chemistry.chemical_compound, chemistry, Biochemistry, medicine, Animals, Molecular Medicine, Female, Enantiomer, Receptor, Fluorescent Dyes, Alexa Fluor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6392e5455ef07a3d27177b768c546ef3Test
https://doi.org/10.1124/mol.109.057687Test

المؤلفون: Joseph H. Steinbach, A D Rodríguez, Ping Li, Brad D. Manion, Vesna A. Eterovic, Alex S. Evers, David E. Reichert, Gustav Akk

المصدر: British Journal of Pharmacology. 153:598-608

مصطلحات موضوعية: Pharmacology, Pregnanolone, medicine.medical_specialty, Neuroactive steroid, GABAA receptor, Allopregnanolone, Biology, chemistry.chemical_compound, Endocrinology, Nicotinic agonist, Mechanism of action, chemistry, Internal medicine, medicine, lipids (amino acids, peptides, and proteins), medicine.symptom, Receptor, health care economics and organizations, Acetylcholine receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d3b268a3dc2c38a64998b766b455b245Test
https://doi.org/10.1038/sj.bjp.0707597Test