دورية أكاديمية
A Clinicopathologic Comparison Between Early-Onset and Late-Onset Small Bowel Adenocarcinoma: A Multicenter International Study
| العنوان: | A Clinicopathologic Comparison Between Early-Onset and Late-Onset Small Bowel Adenocarcinoma: A Multicenter International Study |
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| المؤلفون: | Arpa Giovanni, Vanoli Alessandro, Antoci Francesca, Lenti Marco Vincenzo, Di Sabatino Antonio, Guerini Camilla, Grillo Federica, Bianchi Paola Ilaria, Aronico Nicola, Libera Laura, Furlan Daniela, Travaglino Erica, Nesi Gabriella, Sampietro Gianluca, Ardizzone Sandro, Fociani Paolo, Fiocca Roberto, Latella Giovanni, Sessa Fausto, D’Errico Antonietta, Malvi Deborah, Mescoli Claudia, Rugge Massimo, Ferrero tefano, Poggioli Gilberto, Rizzello Fernando, Macciomei Maria C, Santini Donatella, Volta mberto, De Giorgio Roberto, Caio Giacomo, Calabrò Antonio, Ciacci Carolina, D’Armiento aria, Rizzo Aroldo, Solina Gaspare, Tonelli Francesco, Villanacci Vincenzo, Cannizzaro enato, Canzonieri Vincenzo, Florena Ada M, Biancone Livia, Monteleone Giovanni, Caronna Roberto, Ciardi Antonio, Elli Luca, Caprioli Flavio, Vecchi Maurizio, D’Incà Renata, Zingone Fabiana, D’Odorico Anna, Oreggia Barbara, Bonetti uca eggiani, Astegiano Marco, Cantoro Laura, Papi Claudio, Sandri Giancarlo, Silano Marco, Usai Paolo, Perfetti Vittorio |
| المساهمون: | Arpa, Giovanni, Vanoli, Alessandro, Antoci, Francesca, Lenti Marco, Vincenzo, Di Sabatino, Antonio, Guerini, Camilla, Grillo, Federica, Bianchi Paola, Ilaria, Aronico, Nicola, Libera, Laura, Furlan, Daniela, Travaglino, Erica, Nesi, Gabriella, Sampietro, Gianluca, Ardizzone, Sandro, Fociani, Paolo, Fiocca, Roberto, Latella, Giovanni, Sessa, Fausto, Antonietta, D’Errico, Malvi, Deborah, Mescoli, Claudia, Rugge, Massimo, Ferrero, Tefano, Poggioli, Gilberto, Rizzello, Fernando, Macciomei Maria, C, SANTINI MURATORI, Donatella, Volta, Mberto, De Giorgio, Roberto, Caio, Giacomo, Calabrò, Antonio, Ciacci, Carolina, D’Armiento, Aria, Rizzo, Aroldo, Solina, Gaspare, Tonelli, Francesco, Villanacci, Vincenzo, Cannizzaro, Enato, Canzonieri, Vincenzo, Florena Ada, M, Biancone, Livia, Monteleone, Giovanni, Caronna, Roberto, Ciardi, Antonio, Elli, Luca, Caprioli, Flavio, Vecchi, Maurizio, D’Incà, Renata, Zingone, Fabiana, D’Odorico, Anna, Oreggia, Barbara, Bonetti uca, Eggiani, Astegiano, Marco, Cantoro, Laura, Papi, Claudio, Sandri, Giancarlo, Silano, Marco, Usai, Paolo, Perfetti, Vittorio |
| سنة النشر: | 2024 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | celiac disease, Crohn’s disease, immune-mediated disorder, mismatch repair, small bowel cancer |
| الوصف: | Introduction: Early-onset small bowel adenocarcinoma (EO-SBA) is a rare and poorly characterized entity. Methods: This retrospective study conducted on an international multicenter cohort of 208 patients with SBA aimed at comparing clinicopathologic features of EO-SBA (age younger than 50 years at SBA diagnosis) and late-onset SBA (age 50 years or older at SBA diagnosis). Results: The presence of predisposing pathologic conditions was significantly more common in the EO-SBA group compared with that in the late-onset SBA group ( P = 0.003, Fisher exact test; relative risk: 1.50, 95% confidence interval: 1.20-1.86). This difference is mainly due to the significantly higher prevalence of celiac disease among patients with EO-SBA. Discussion: EO-SBA is strongly associated with predisposing conditions, particularly with celiac disease, highlighting the importance of routine screening for celiac disease in patients with EO-SBA. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/37966091; volume:119; issue:3; firstpage:576; lastpage:579; numberofpages:4; journal:THE AMERICAN JOURNAL OF GASTROENTEROLOGY; https://hdl.handle.net/11573/1705793Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85187156762 |
| DOI: | 10.14309/ajg.0000000000002585 |
| الإتاحة: | https://doi.org/10.14309/ajg.0000000000002585Test https://hdl.handle.net/11573/1705793Test |
| رقم الانضمام: | edsbas.A5D3FFDC |
| قاعدة البيانات: | BASE |
| DOI: | 10.14309/ajg.0000000000002585 |
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