دورية أكاديمية
Cilentan Cichorium intybus L. organs: UHPLC-QqTOF-MS/MS analysis for new antioxidant scenario, exploitable locally and beyond
| العنوان: | Cilentan Cichorium intybus L. organs: UHPLC-QqTOF-MS/MS analysis for new antioxidant scenario, exploitable locally and beyond |
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| المؤلفون: | Simona Piccolella, Marika Fiorentino, Giovanna Cimmino, Assunta Esposito, Severina Pacifico |
| المصدر: | Future Foods, Vol 9, Iss , Pp 100379- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Food processing and manufacture |
| مصطلحات موضوعية: | Cichorium intybus L., Hypogeal and epigeal organs, Bioactives sustainable sources, UHPLC-QqTOF-MS/MS, Antioxidant activity, Plant-based ingredients recovery, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456 |
| الوصف: | In the framework aimed at evaluating the close link between the chemical composition of poorly explored organs of local edible medicinal plants in the Cilento region (Southern Italy) and their recovery for new health products, Cichorium intybus L. was of interest. Ultra-High Performance Liquid Chromatography Quadrupole-Time-Of-Flight tandem Mass Spectrometry (UHPLC-QqTOF-MS/MS) investigation revealed that sesquiterpene lactones characterized roots and stems, while hydroxycinnamic derivatives accumulated in florets, bracts, and leaves. Florets diverged for anthocyanin derivatives, while roots differed by low flavonoid content. Despite shared phytochemical constituents, their ratio was responsible for different antioxidant responses. Notably, extracts, particularly rich in hydroxycinnamoyl derivatives, showed protective effects against oxidative stress induced by hydrogen peroxide in SH-SY5Y and HaCaT cell lines. The wound healing assay revealed marked inhibition of SH-SY5Y cell migration, avoiding wound closure. Overall, the research encourages the use of different organs from Cilentan wild chicory to obtain antioxidant safe and consumer-guaranteed products. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2666-8335 |
| العلاقة: | http://www.sciencedirect.com/science/article/pii/S2666833524000856Test; https://doaj.org/toc/2666-8335Test |
| DOI: | 10.1016/j.fufo.2024.100379 |
| الوصول الحر: | https://doaj.org/article/03223c1de2a648599e4d3d2f14aca175Test |
| رقم الانضمام: | edsdoj.03223c1de2a648599e4d3d2f14aca175 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26668335 |
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| DOI: | 10.1016/j.fufo.2024.100379 |