دورية أكاديمية

The Global Landscape of Pediatric Bacterial Meningitis Data Reported to the World Health Organization-Coordinated Invasive Bacterial Vaccine-Preventable Disease Surveillance Network, 2014-2019.

التفاصيل البيبلوغرافية
العنوان: The Global Landscape of Pediatric Bacterial Meningitis Data Reported to the World Health Organization-Coordinated Invasive Bacterial Vaccine-Preventable Disease Surveillance Network, 2014-2019.
المؤلفون: Nakamura, T, Cohen, AL, Schwartz, S, Mwenda, JM, Weldegebriel, G, Biey, JNM, Katsande, R, Ghoniem, A, Fahmy, K, Rahman, HA, Videbaek, D, Daniels, D, Singh, S, Wasley, A, Rey-Benito, G, de Oliveira, L, Ortiz, C, Tondo, E, Liyanage, JBL, Sharifuzzaman, M, Grabovac, V, Batmunkh, N, Logronio, J, Heffelfinger, J, Fox, K, De Gouveia, L, von Gottberg, A, Du Plessis, M, Kwambana-Adams, B, Antonio, M, El Gohary, S, Azmy, A, Gamal, A, Voropaeva, E, Egorova, E, Urban, Y, Duarte, C, Veeraraghavan, B, Saha, S, Howden, B, Sait, M, Jung, S, Bae, S, Litt, D, Seaton, S, Slack, M, Antoni, S, Ouattara, M, Van Beneden, C, Serhan, F
بيانات النشر: Oxford University Press (OUP)
سنة النشر: 2021
المجموعة: The University of Melbourne: Digital Repository
الوصف: BACKGROUND: The World Health Organization (WHO) coordinates the Global Invasive Bacterial Vaccine-Preventable Diseases (IB-VPD) Surveillance Network to support vaccine introduction decisions and use. The network was established to strengthen surveillance and laboratory confirmation of meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis. METHODS: Sentinel hospitals report cases of children <5 years of age hospitalized for suspected meningitis. Laboratories report confirmatory testing results and strain characterization tested by polymerase chain reaction. In 2019, the network included 123 laboratories that follow validated, standardized testing and reporting strategies. RESULTS: From 2014 through 2019, >137 000 suspected meningitis cases were reported by 58 participating countries, with 44.6% (n = 61 386) reported from countries in the WHO African Region. More than half (56.6%, n = 77 873) were among children <1 year of age, and 4.0% (n = 4010) died among those with reported disease outcome. Among suspected meningitis cases, 8.6% (n = 11 798) were classified as probable bacterial meningitis. One of 3 bacterial pathogens was identified in 30.3% (n = 3576) of these cases, namely S. pneumoniae (n = 2177 [60.9%]), H. influenzae (n = 633 [17.7%]), and N. meningitidis (n = 766 [21.4%]). Among confirmed bacterial meningitis cases with outcome reported, 11.0% died; case fatality ratio varied by pathogen (S. pneumoniae, 12.2%; H. influenzae, 6.1%; N. meningitidis, 11.0%). Among the 277 children who died with confirmed bacterial meningitis, 189 (68.2%) had confirmed S. pneumoniae. The proportion of pneumococcal cases with pneumococcal conjugate vaccine (PCV) serotypes decreased as the number of countries implementing PCV increased, from 77.8% (n = 273) to 47.5% (n = 248). Of 397 H. influenzae specimens serotyped, 49.1% (n = 195) were type b. Predominant N. meningitidis serogroups varied by region. CONCLUSIONS: This multitier, global surveillance network has supported ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 0022-1899
1537-6613
العلاقة: pii: 6361066; Nakamura, T., Cohen, A. L., Schwartz, S., Mwenda, J. M., Weldegebriel, G., Biey, J. N. M., Katsande, R., Ghoniem, A., Fahmy, K., Rahman, H. A., Videbaek, D., Daniels, D., Singh, S., Wasley, A., Rey-Benito, G., de Oliveira, L., Ortiz, C., Tondo, E., Liyanage, J. B. L. ,. Serhan, F. (2021). The Global Landscape of Pediatric Bacterial Meningitis Data Reported to the World Health Organization-Coordinated Invasive Bacterial Vaccine-Preventable Disease Surveillance Network, 2014-2019. J Infect Dis, 224 (12 Suppl 2), pp.S161-S173. https://doi.org/10.1093/infdis/jiab217Test.; http://hdl.handle.net/11343/289803Test
الإتاحة: https://doi.org/10.1093/infdis/jiab217Test
http://hdl.handle.net/11343/289803Test
حقوق: CC BY ; https://creativecommons.org/licenses/by/4.0Test
رقم الانضمام: edsbas.B4020300
قاعدة البيانات: BASE