دورية أكاديمية
Mycobacterium bovis deleted in mce2 and phoP loci protects C57BL/6 mice against tuberculosis
| العنوان: | Mycobacterium bovis deleted in mce2 and phoP loci protects C57BL/6 mice against tuberculosis |
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| المؤلفون: | Garcia, Elizabeth Andrea, Bianco, María Veronica, Blanco, Federico Carlos, Bigi, Fabiana |
| المصدر: | Journal Of Infection In Developing Countries 10 (8): 892-894 (August 2016) |
| سنة النشر: | 2016 |
| المجموعة: | Inta Digital (ID - Instituto Nacional de Tecnología Agropecuaria) |
| مصطلحات موضوعية: | Enfermedades de los Animales, Mycobacterium Bovis, Tuberculosis, Infección por Mycobacterium Bovis, Animal Diseases, Mycobacterium Bovis Infections |
| الوصف: | Here we confirm the efficacy of MbΔmce2-phoP to protect mice against bTB challenge and we demonstrated that this new attenuated strain is safer than our previous bTB vaccine MbΔmce2. Altogether these results support the further assessment of this candidate in cattle model of bTB.Experiments with mice were performed in compliance with the regulations of the Institutional Animal Care and Use Committee (CICUAE) of INTA (61/2014). ; Inst. de Biotecnología ; Fil: Garcia, Elizabeth Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina ; Fil: Bianco, María Veronica. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; Argentina ; Fil: Blanco, Federico Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina ; Fil: Bigi, Fabiana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://hdl.handle.net/20.500.12123/1053Test; https://jidc.org/index.php/journal/article/view/27580338/1568Test; García E, Bianco M, Blanco F, Bigi F (2016) Mycobacterium bovis deleted in mce2 and phoP loci protects C57BL/6 mice against tuberculosis. The Journal Of Infection In Developing Countries 10 (08): 892-894. https://doi.org/10.3855/jidc.7721Test; 2036-6590 (Print); 1972-2680 (Online); https://doi.org/10.3855/jidc.7721Test |
| DOI: | 10.3855/jidc.7721 |
| الإتاحة: | https://doi.org/20.500.12123/1053Test https://doi.org/10.3855/jidc.7721Test https://hdl.handle.net/20.500.12123/1053Test https://jidc.org/index.php/journal/article/view/27580338/1568Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.9E28638B |
| قاعدة البيانات: | BASE |
| DOI: | 10.3855/jidc.7721 |
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