المؤلفون: Baker, Brenda, Xia, Shuting, Partridge, Wesley, Kwoh, T, Bhanot, Sanjay, Geary, Richard, Tsimikas, Sotirios

المصدر: Nucleic Acid Therapeutics. 33(1)

مصطلحات موضوعية: integrated safety analysis, ligand-conjugated antisense technology, phase 2, randomized placebo-controlled trials, triantennary N-acetylgalactosamine, Humans, Oligonucleotides, Antisense, Ligands, Hepatocytes, Oligonucleotides, RNA

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/38g398k8Test

المؤلفون: Loomba, Rohit, Morgan, Erin, Watts, Lynnetta, Xia, Shuting, Hannan, Lisa A, Geary, Richard S, Baker, Brenda F, Bhanot, Sanjay

المصدر: The Lancet Gastroenterology & Hepatology. 5(9)

مصطلحات موضوعية: Prevention, Chronic Liver Disease and Cirrhosis, Clinical Research, Digestive Diseases, Patient Safety, Clinical Trials and Supportive Activities, Hepatitis, Liver Disease, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Oral and gastrointestinal, Good Health and Well Being, Aged, Body Mass Index, Canada, Case-Control Studies, Diabetes Mellitus, Type 2, Diacylglycerol O-Acyltransferase, Double-Blind Method, Drug Tolerance, Female, Humans, Hungary, Injections, Subcutaneous, Intra-Abdominal Fat, Magnetic Resonance Imaging, Male, Middle Aged, Non-alcoholic Fatty Liver Disease, Oligonucleotides, Antisense, Placebos, Poland, Safety, Treatment Outcome

الوصول الحر: https://escholarship.org/uc/item/3q1381stTest

المؤلفون: Crooke, Stanley T, Baker, Brenda F, Pham, Nguyen C, Hughes, Steven G, Kwoh, T Jesse, Cai, Danlin, Tsimikas, Sotirios, Geary, Richard S, Bhanot, Sanjay

المصدر: Nucleic Acid Therapeutics. 28(1)

مصطلحات موضوعية: Biological Sciences, Clinical Research, Clinical Trials and Supportive Activities, Kidney Disease, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Renal and urogenital, Adult, Apolipoproteins, Clinical Trials, Phase II as Topic, Clinical Trials, Phase III as Topic, Creatinine, Diabetes Mellitus, Factor XI, Female, Glomerular Filtration Rate, Humans, Hyperlipidemias, Male, Middle Aged, Obesity, Oligonucleotides, Antisense, Patient Safety, Protein Tyrosine Phosphatases, Non-Receptor, Randomized Controlled Trials as Topic, Receptor Protein-Tyrosine Kinases, Receptors, Glucocorticoid, Thrombosis, antisense, oligonucleotide, kidney, safety, clinical trials, humans, Technology, Biochemistry & Molecular Biology, Pharmacology & Pharmacy, Biological sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6qg2g063Test

المؤلفون: Baker, Brenda F., Xia, Shuting, Partridge, Wesley, Engelhardt, Jeffery A., Tsimikas, Sotirios, Crooke, Stanley T., Bhanot, Sanjay, Geary, Richard S.

المصدر: Nucleic Acid Therapeutics ; volume 34, issue 1, page 18-25 ; ISSN 2159-3337 2159-3345

الإتاحة: https://doi.org/10.1089/nat.2023.0026Test

المؤلفون: Saenz de Urturi Indart, Diego, Buqué García, Xabier, Porteiro, Begoña, Folgueira, Cintia, Mora, Alfonso, Delgado, Teresa C., Prieto Fernández, Endika, Olaizola Rebe, Paula, Gómez Santos, Beatriz, Apodaka Biguri, Maider, González Romero, Francisco, Nieva Zuluaga, Ane, Ruiz de Gauna Madariaga, Mikel, Goikoetxea Usandizaga, Naroa, García Rodríguez, Juan Luis, Gutiérrez de Juan, Virginia, Aurrekoetxea Galindo, Igor, Montalvo Romeral, Valle, Novoa, Eva, Martín Guerrero, Idoia, Varela Rey, Marta, Bhanot, Sanjay, Lee, Richard, Bañales Asurmendi, Jesús María, Syn, Wing-Kin, Sabio, Guadalupe, Martínez Chantar, María Luz, Nogueiras Pozo, Rubén, Aspichueta Celaá, Patricia

مصطلحات موضوعية: growth-factor 21, fatty-acid oxidation, s-adenosylmethionine, insulin sensitivity, hepatic steatosis, rat-liver, mice, diet, restriction, metabolism

وصف الملف: application/pdf

العلاقة: info:eu-repo/grantAgreement/MICIU/RTI2018-095134-B-100; info:eu-repo/grantAgreement/MICIU/RTI2018-099413-B-I00; info:eu-repo/grantAgreement/MICIU/RED2018-102379-T; info:eu-repo/grantAgreement/MICIU/RTI2018-096759-A-100; info:eu-repo/grantAgreement/MICIU/FJC2018-035449-I; info:eu-repo/grantAgreement/MINECO/SEV-2016-0644; info:eu-repo/grantAgreement/MICINN/PID2019-104399RB-I00; info:eu-repo/grantAgreement/MICINN/PID2020119486RB-100; https://www.nature.com/articles/s41467-022-28749-zTest; Nature Communications 13(1) : (2022) // Article ID 1096; http://hdl.handle.net/10810/57907Test

الإتاحة: https://doi.org/10.1038/s41467-022-28749-zTest
http://hdl.handle.net/10810/57907Test

المؤلفون: Walsh, Michael, Bethune, Claudette, Smyth, Andrew, Tyrwhitt, Jessica, Jung, Shiangtung W., Yu, Rosie Z., Wang, Yanfeng, Geary, Richard S., Weitz, Jeffrey, Bhanot, Sanjay

المصدر: Kidney International Reports ; volume 7, issue 2, page 200-209 ; ISSN 2468-0249

الإتاحة: https://doi.org/10.1016/j.ekir.2021.11.011Test
https://api.elsevier.com/content/article/PII:S2468024921015175?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2468024921015175?httpAccept=text/plainTest

المؤلفون: Bhanot, Sanjay

وصف الملف: 2038240 bytes; application/pdf

الإتاحة: http://hdl.handle.net/2429/7201Test

المؤلفون: Kong, Dong, Banks, Alexander, Zhang, Lin, Rodgers, Joseph, Pirinen, Eija, Pulinilkunnil, Thomas, Gong, Fengying, Wang, Ya-chin, Cen, Yana, Sauve, Anthony, Asara, John, Peroni, Odile, Monia, Brett, Bhanot, Sanjay, Alhonen, Leena, Puigserver, Pere, Kahn, Barbara, Kraus, Daniel, Yang, Qin

المصدر: Nature. 508(7495)

مصطلحات موضوعية: Acetyltransferases, Adipocytes, Adipose Tissue, Adipose Tissue, White, Animals, Diabetes Mellitus, Type 2, Diet, Energy Metabolism, Fatty Liver, Gene Knockdown Techniques, Glucose Intolerance, Glucose Transporter Type 4, Insulin Resistance, Liver, Male, Mice, Mice, Inbred C57BL, NAD, Niacinamide, Nicotinamide N-Methyltransferase, Obesity, Ornithine Decarboxylase, Oxidoreductases Acting on CH-NH Group Donors, S-Adenosylmethionine, Sirtuin 1, Spermine, Thinness, Polyamine Oxidase

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4k9799h0Test

المؤلفون: Kraus, Daniel, Yang, Qin, Kong, Dong, Banks, Alexander S, Zhang, Lin, Rodgers, Joseph T, Pirinen, Eija, Pulinilkunnil, Thomas C, Gong, Fengying, Wang, Ya-chin, Cen, Yana, Sauve, Anthony A, Asara, John M, Peroni, Odile D, Monia, Brett P, Bhanot, Sanjay, Alhonen, Leena, Puigserver, Pere, Kahn, Barbara B

المصدر: Nature. 508(7495)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Nutrition, Obesity, Diabetes, Liver Disease, Digestive Diseases, Aetiology, 2.1 Biological and endogenous factors, Stroke, Cancer, Oral and gastrointestinal, Metabolic and endocrine, Cardiovascular, Acetyltransferases, Adipocytes, Adipose Tissue, Adipose Tissue, White, Animals, Diabetes Mellitus, Type 2, Diet, Energy Metabolism, Fatty Liver, Gene Knockdown Techniques, Glucose Intolerance, Glucose Transporter Type 4, Insulin Resistance, Liver, Male, Mice, Mice, Inbred C57BL, NAD, Niacinamide, Nicotinamide N-Methyltransferase, Ornithine Decarboxylase, Oxidoreductases Acting on CH-NH Group Donors, S-Adenosylmethionine, Sirtuin 1, Spermine, Thinness, Polyamine Oxidase, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7mh5z02vTest

المؤلفون: Willmann, Stefan, Marostica, Eleonora, Snelder, Nelleke, Solms, Alexander, Jensen, Markus, Lobmeyer, Maximilian, Lensing, Anthonie W. A., Bethune, Claudette, Morgan, Erin, Yu, Rosie Z., Wang, Yanfeng, Jung, Shiangtung W., Geary, Richard, Bhanot, Sanjay

المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 10, issue 8, page 890-901 ; ISSN 2163-8306 2163-8306

الإتاحة: https://doi.org/10.1002/psp4.12663Test