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1دورية أكاديمية
المؤلفون: Pin-Kuang Lai, Austin Gallegos, Neil Mody, Hasige A. Sathish, Bernhardt L. Trout
المصدر: mAbs, Vol 14, Iss 1 (2022)
مصطلحات موضوعية: machine learning, molecular dynamics simulations, antibody aggregation, antibody viscosity, developability, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Pin-Kuang Lai, Gaurav Ghag, Yao Yu, Veronica Juan, Laurence Fayadat-Dilman, Bernhardt L. Trout
المصدر: mAbs, Vol 13, Iss 1 (2021)
مصطلحات موضوعية: Monoclonal antibody self-interaction, monoclonal antibody viscosity, diffusion interaction parameter, IgG1, IgG4 S228P, IgG4P, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Pin-Kuang Lai, James W. Swan, Bernhardt L. Trout
المصدر: mAbs, Vol 13, Iss 1 (2021)
مصطلحات موضوعية: Antibody viscosity, coarse-grained models, molecular dynamics simulations, hydrodynamic calculations, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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4دورية أكاديمية
المصدر: mAbs, Vol 12, Iss 1 (2020)
مصطلحات موضوعية: Preferential interaction coefficients, proline, arginine.HCl, Nacl, mAbs, aggregation, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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5دورية أكاديمية
المؤلفون: Pin-Kuang Lai (1999471), Amendra Fernando (1400587), Theresa K. Cloutier (9993534), Yatin Gokarn (9993537), Jifeng Zhang (352541), Walter Schwenger (9993540), Ravi Chari (2207155), Cesar Calero-Rubio (2864690), Bernhardt L. Trout (195616)
مصطلحات موضوعية: Biochemistry, Pharmacology, Biotechnology, Immunology, Hematology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, Concentrated Therapeutic Antibodies, concentration-dependent solution vi., 10 mM histidine-HCl, antibody drug design, Fv region, charge, mAb, machine Learning Applied
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6
المؤلفون: Muhammad A. Hagras, Ryan A. Marek, Feras Hatahet, Bernhardt L. Trout
المصدر: The journal of physical chemistry. B. 126(32)
مصطلحات موضوعية: Hydroxyl Radical, Superoxides, Materials Chemistry, Computer Simulation, Cysteine, Physical and Theoretical Chemistry, Oxidation-Reduction, Surfaces, Coatings and Films
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52c38554287ab5b334bdac0a4f2bb53Test
https://pubmed.ncbi.nlm.nih.gov/35895909Test -
7
المؤلفون: Jonathan S. Kingsbury, Cesar Calero-Rubio, Amendra Fernando, Yatin R. Gokarn, Pin-Kuang Lai, Theresa K. Cloutier, Kevin T. Halloran, Bernhardt L. Trout
المصدر: Journal of Pharmaceutical Sciences. 110:1583-1591
مصطلحات موضوعية: High concentration, Support Vector Machine, Correlation coefficient, business.industry, Computer science, Small number, Linear model, Pharmaceutical Science, Feature selection, 02 engineering and technology, 021001 nanoscience & nanotechnology, Machine learning, computer.software_genre, 030226 pharmacology & pharmacy, Machine Learning, Correlation, Support vector machine, 03 medical and health sciences, 0302 clinical medicine, Therapeutic antibody, Artificial intelligence, 0210 nano-technology, business, computer
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca77fb33dddf2da6c20e9967fcf3794Test
https://doi.org/10.1016/j.xphs.2020.12.014Test -
8
المصدر: The Journal of Physical Chemistry B. 124:9840-9851
مصطلحات موضوعية: Reaction mechanism, 010304 chemical physics, Chemistry, Hydrogen Peroxide, 010402 general chemistry, 01 natural sciences, Sulfenic Acids, Transition state, 0104 chemical sciences, Surfaces, Coatings and Films, chemistry.chemical_compound, Computational chemistry, Covalent bond, 0103 physical sciences, Materials Chemistry, Quantum Theory, Molecule, Computer Simulation, Protein folding, Sulfenic acid, Density functional theory, Cysteine, Disulfides, Physical and Theoretical Chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9cd33ead59c08cf6305cdec53eec65Test
https://doi.org/10.1021/acs.jpcb.0c07510Test -
9
المصدر: Molecular Pharmaceutics. 17:3589-3599
مصطلحات موضوعية: Elastic net regularization, Sucrose, Proline, Computer science, Chemistry, Pharmaceutical, Stability (learning theory), Pharmaceutical Science, Excipient, 02 engineering and technology, Sodium Chloride, Arginine, Machine learning, computer.software_genre, 030226 pharmacology & pharmacy, Excipients, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Feature set, Viscosity, business.industry, Antibodies, Monoclonal, Trehalose, 021001 nanoscience & nanotechnology, Viscosity (programming), Molecular Medicine, Artificial intelligence, 0210 nano-technology, business, computer, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9950f11f30af2510c594b7e27d8037Test
https://doi.org/10.1021/acs.molpharmaceut.0c00629Test -
10
المؤلفون: Bernhardt L. Trout, Hadi Mehrabian
المصدر: The Journal of Physical Chemistry C. 124:18983-18992
مصطلحات موضوعية: Chemistry, In silico, Clathrate hydrate, Metadynamics, Sampling (statistics), 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, General Energy, Adsorption, Chemical physics, Molecule, Physical and Theoretical Chemistry, 0210 nano-technology, Hydrate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a899f79d9e28e0681e3f3dace5dcf585Test
https://doi.org/10.1021/acs.jpcc.0c03251Test