المؤلفون: Hannes Glaβ, Peter Heutink, Marcel Naumann, Arun Pal, Nicole Kreiter, Benedikt Kretner, René Günther, Masin Abo-Rady, Andreas Hermann, Ashutosh Dhingra, Tobias M. Böckers, Jared Sterneckert, Banaja P. Dash, Julia Japtok

المصدر: Life Science Alliance
Life science alliance 4(4), e202000764-(2021). doi:10.26508/lsa.202000764

مصطلحات موضوعية: 0301 basic medicine, metabolism [Cytoskeleton], Health, Toxicology and Mutagenesis, Apoptosis, Plant Science, metabolism [Axons], 0302 clinical medicine, C9orf72, Loss of Function Mutation, DNA Breaks, Double-Stranded, Axon, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Cells, Cultured, Cellular Senescence, Cytoskeleton, Research Articles, Motor Neurons, Ecology, pathology [Axons], Neurodegeneration, physiopathology [Amyotrophic Lateral Sclerosis], Cell biology, DNA-Binding Proteins, genetics [Amyotrophic Lateral Sclerosis], medicine.anatomical_structure, Gain of Function Mutation, metabolism [Organelles], Research Article, Programmed cell death, TARDBP protein, human, genetics [DNA-Binding Proteins], Biology, Biochemistry, Genetics and Molecular Biology (miscellaneous), 03 medical and health sciences, ddc:570, medicine, Humans, pathology [Amyotrophic Lateral Sclerosis], genetics [C9orf72 Protein], Loss function, Repetitive Sequences, Nucleic Acid, Phenocopy, Organelles, C9orf72 Protein, Amyotrophic Lateral Sclerosis, metabolism [Motor Neurons], FUS protein, human, medicine.disease, Axons, 030104 developmental biology, nervous system, Microscopy, Fluorescence, RNA-Binding Protein FUS, Energy Metabolism, genetics [RNA-Binding Protein FUS], 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c8e9fe2a2303f8e4b32f90e68075bfTest
https://pubmed.ncbi.nlm.nih.gov/33619157Test

المؤلفون: Johannes Trambauer, Benedikt Kretner, Harald Steiner, Akio Fukumori

المصدر: New York, NY [u.a.] : Elsevier, Methods in Enzymology 584, 157-183 (2017). doi:10.1016/bs.mie.2016.10.013
Enzymology at the Membrane Interface: Intramembrane Proteases / Trambauer, J. ; : Elsevier, 2017, ; ISSN: 00766879 ; ISBN: 9780128122136 ; doi:10.1016/bs.mie.2016.10.013

مصطلحات موضوعية: 0301 basic medicine, Immunoprecipitation, therapeutic use [Enzyme Activators], 03 medical and health sciences, Enzyme activator, ddc:570, medicine, Amyloid precursor protein, agonists [Amyloid beta-Peptides], drug therapy [Alzheimer Disease], Humans, Binding site, enzymology [Protein Aggregation, Pathological], Binding Sites, biology, drug therapy [Protein Aggregation, Pathological], Chemistry, P3 peptide, enzymology [Alzheimer Disease], medicine.disease, methods [Molecular Biology], metabolism [Amyloid Precursor Protein Secretases], Transmembrane domain, 030104 developmental biology, Biochemistry, chemistry [Amyloid Precursor Protein Secretases], biology.protein, chemistry [Amyloid beta-Peptides], Alzheimer's disease, Amyloid precursor protein secretase, chemistry [Enzyme Activators]

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192494ed27c8f67071dd98484d5f4ec9Test
https://pub.dzne.de/record/144542Test

المؤلفون: Harald Steiner, Armin Giese, Thomas Arzberger, Christian Haass, Benedikt Kretner, Janina Mielke, Akio Fukumori, Elisabeth Kremmer, Peer-Hendrik Kuhn, Stefan F. Lichtenthaler, Johannes Trambauer

المصدر: EMBO molecular medicine 8(5), 458-465 (2016). doi:10.15252/emmm.201505952
EMBO Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Mutant, pathology [Frontal Lobe], Bioinformatics, medicine.disease_cause, pathology [Alzheimer Disease], 0302 clinical medicine, Amyloid precursor protein, presenilin, metabolism [Peptide Fragments], Mutation, Microscopy, biology, Chemistry, metabolism [Presenilin-1], Neurodegeneration, neurodegeneration, genetics [Presenilin-1], Alzheimer's disease, Immunohistochemistry, Frontal Lobe, Cell biology, amyloid‐β peptide 43, genetics [Mutant Proteins], Molecular Medicine, Amyloid, metabolism [Amyloid beta-Peptides], amyloid beta-protein (1-43), Presenilin, 03 medical and health sciences, PSEN1 protein, human, Alzheimer Disease, Report, mental disorders, medicine, Presenilin-1, Humans, ddc:610, metabolism [Mutant Proteins], Loss function, γ‐secretase, Amyloid beta-Peptides, medicine.disease, Peptide Fragments, nervous system diseases, 030104 developmental biology, biology.protein, Mutant Proteins, 030217 neurology & neurosurgery, Reports, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a36f51821741182e68cb45ec796ad96Test
https://pub.dzne.de/record/138553Test

المؤلفون: Amelie Gutsmiedl, Benedikt Kretner, Akio Fukumori, Richard M. Page, Karlheinz Baumann, Guido Galley, Christian Haass, Thomas Luebbers, Harald Steiner

المصدر: Alzheimer's & Dementia. 7

مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Chemistry, Health Policy, Mutant, Neurology (clinical), Geriatrics and Gerontology, Gamma secretase, Presenilin, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::231a735603ff67f625ebb2eabb39a0cdTest
https://doi.org/10.1016/j.jalz.2011.05.262Test

المؤلفون: Guido Galley, Amelie Gutsmiedl, Karlheinz Baumann, Benedikt Kretner, Akio Fukumori, Thomas Luebbers, Richard M. Page, Harald Steiner, Christian Haass

المصدر: The journal of biological chemistry 286(17), 15240-15251 (2011). doi:10.1074/jbc.M110.213587

مصطلحات موضوعية: Amyloid, Protein subunit, Mutant, medicine.disease_cause, Biochemistry, Presenilin, drug effects [Presenilins], APP protein, human, Cell Line, pharmacology [Anti-Inflammatory Agents, Non-Steroidal], Amyloid beta-Protein Precursor, medicine, Humans, drug effects [Peptide Fragments], Molecular Biology, drug effects [Amyloid beta-Protein Precursor], Mutation, Amyloid beta-Peptides, biology, Anti-Inflammatory Agents, Non-Steroidal, Presenilins, Cell Biology, drug effects [Amyloid beta-Peptides], medicine.disease, amyloid beta-protein (1-42), Peptide Fragments, drug effects [Amyloid Precursor Protein Secretases], Cell culture, Protein Synthesis and Degradation, ddc:540, biology.protein, genetics [Presenilins], Alzheimer's disease, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eea2c1ae3195c97857d3a447f67e199Test
https://europepmc.org/articles/PMC3083200Test/

المؤلفون: Blanca Isabel Pérez-Revuelta, Benedikt Kretner, Sven Lammich, Christian Haass, Akio Fukumori, Harald Steiner, Edith Winkler

المصدر: Alzheimer's & Dementia. 5

مصطلحات موضوعية: Protease, Functional analysis, biology, Epidemiology, Chemistry, Health Policy, medicine.medical_treatment, Active site, Domain (software engineering), Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, biology.protein, Biophysics, Neurology (clinical), γ secretase, Geriatrics and Gerontology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1b4b0df10ab5d535c36ab428502a7a9dTest
https://doi.org/10.1016/j.jalz.2009.05.224Test

المؤلفون: Sven Lammich, Aya Yamasaki, Christian Haass, Harald Steiner, Blanca Isabel Pérez-Revuelta, Benedikt Kretner

المصدر: Alzheimer's & Dementia. 4

مصطلحات موضوعية: Protease, biology, Epidemiology, Chemistry, Health Policy, medicine.medical_treatment, Active site, Cleavage (embryo), Presenilin, Mutational analysis, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, biology.protein, Biophysics, Neurology (clinical), γ secretase, Geriatrics and Gerontology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e40f73f94a2f3d1dbaffb4810a23281cTest
https://doi.org/10.1016/j.jalz.2008.05.521Test