المؤلفون: Echevarria-Cooper, Dennis M, Hawkins, Nicole A, Misra, Sunita N, Huffman, Alexandra M, Thaxton, Tyler, Thompson, Christopher H, Ben-Shalom, Roy, Nelson, Andrew D, Lipkin, Anna M, George, Alfred L, Bender, Kevin J, Kearney, Jennifer A

المصدر: Human Molecular Genetics. 31(17)

مصطلحات موضوعية: Biological Sciences, Genetics, Epilepsy, Neurodegenerative, Pediatric, Basic Behavioral and Social Science, Brain Disorders, Autism, Mental Health, Behavioral and Social Science, Intellectual and Developmental Disabilities (IDD), Neurosciences, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Autism Spectrum Disorder, Calcium, Humans, Mice, NAV1.2 Voltage-Gated Sodium Channel, Permeability, Seizures, Sodium, Sodium Channels, Medical and Health Sciences, Genetics & Heredity

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5dr8c9hgTest
https://escholarship.org/content/qt5dr8c9hg/qt5dr8c9hg.pdfTest

المؤلفون: Quinn, Shir, Zhang, Nan, Fenton, Timothy A., Brusel, Marina, Muruganandam, Preethi, Peleg, Yoav, Giladi, Moshe, Haitin, Yoni, Lerche, Holger, Bassan, Haim, Liu, Yuanyuan, Ben-Shalom, Roy, Rubinstein, Moran

المساهمون: BMBF Berlin, Tel Aviv Sourasky Medical Center, Hartwell Foundation, Israel Cancer Association, Tel Aviv University Faculty of Medicine, Israel Cancer Research Fund, DFG, ISF

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ; volume 1870, issue 5, page 167127 ; ISSN 0925-4439

مصطلحات موضوعية: Molecular Biology, Molecular Medicine

الإتاحة: https://doi.org/10.1016/j.bbadis.2024.167127Test
https://api.elsevier.com/content/article/PII:S0925443924001169?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0925443924001169?httpAccept=text/plainTest

المؤلفون: Ben-Shalom, Roy, Ladd, Alexander, Artherya, Nikhil S, Cross, Christopher, Kim, Kyung Geun, Sanghevi, Hersh, Korngreen, Alon, Bouchard, Kristofer E, Bender, Kevin J

مصطلحات موضوعية: Neurons, Membrane Potentials, Algorithms, Computer Graphics, Computer Simulation, Biophysical simulations, Compartmental models, Conductance-based models, Electrophysiology, Graphical Processing Unit, Neurosciences, Bioengineering, Psychology, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4c07g9crTest

المؤلفون: Spratt, Perry WE, Alexander, Ryan PD, Ben-Shalom, Roy, Sahagun, Atehsa, Kyoung, Henry, Keeshen, Caroline M, Sanders, Stephan J, Bender, Kevin J

المصدر: Cell Reports. 36(5)

مصطلحات موضوعية: Neurodegenerative, Brain Disorders, Epilepsy, Neurosciences, Intellectual and Developmental Disabilities (IDD), Aetiology, 2.1 Biological and endogenous factors, Neurological, Action Potentials, Animals, Dendrites, Gene Deletion, Mice, Inbred C57BL, Mice, Knockout, NAV1.2 Voltage-Gated Sodium Channel, Neocortex, Pyramidal Cells, NaV1.2, SCN2A, autism, autism spectrum disorder, dendrite, dynamic clamp, epilepsy, prefrontal cortex, pyramidal cell, Biochemistry and Cell Biology, Medical Physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8nb3d8pgTest

المؤلفون: Ladd, Alexander, Kim, Kyung Geun, Balewski, Jan, Bouchard, Kristofer, Ben-Shalom, Roy

مصطلحات موضوعية: Information and Computing Sciences, Biomedical and Clinical Sciences, Neurosciences, Machine Learning, Bioengineering, Neurological, biophysical neuron model, high performance computing, evolutionary algorithms, non-convex optimization, strong scaling, weak scaling, electrophysiology, Cognitive Sciences, Applied computing, Machine learning

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0kc51444Test

المؤلفون: Thompson, Christopher H, Ben-Shalom, Roy, Bender, Kevin J, George, Alfred L

المصدر: The Journal of General Physiology. 152(3)

مصطلحات موضوعية: Neurodegenerative, Neurosciences, Epilepsy, Brain Disorders, Pediatric, Genetics, 1.1 Normal biological development and functioning, Underpinning research, 2.1 Biological and endogenous factors, Aetiology, Neurological, Alternative Splicing, Brain, Brain Diseases, Genetic Variation, Humans, NAV1.2 Voltage-Gated Sodium Channel, Neurons, Patch-Clamp Techniques, Protein Isoforms, RNA, Messenger, Physiology, Medical Physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0wb14751Test

المؤلفون: Spratt, Perry WE, Ben-Shalom, Roy, Keeshen, Caroline M, Burke, Kenneth J, Clarkson, Rebecca L, Sanders, Stephan J, Bender, Kevin J

المصدر: Neuron. 103(4)

مصطلحات موضوعية: Hippocampus, Pyramidal Cells, Prefrontal Cortex, Neocortex, Dendrites, Animals, Mice, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, N-Methylaspartate, Protein Engineering, Social Behavior, Maze Learning, Calcium Signaling, Gene Expression Regulation, Developmental, Action Potentials, Heterozygote, Female, Male, Miniature Postsynaptic Potentials, NAV1.2 Voltage-Gated Sodium Channel, Autism Spectrum Disorder, 2-photon imaging, NaV1.2, Scn2a, action potential backpropagation, autism spectrum disorder, dendritic excitability, electrophysiology, haploinsufficiency, intellectual disability, sodium channel, synaptic plasticity, Pediatric, Intellectual and Developmental Disabilities (IDD), Genetics, Mental Health, Neurosciences, Autism, Brain Disorders, Underpinning research, Aetiology, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Neurological, Psychology, Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5kx9d7t8Test

المؤلفون: Athilingam, Jegath C, Ben-Shalom, Roy, Keeshen, Caroline M, Sohal, Vikaas S, Bender, Kevin J

مصطلحات موضوعية: Prefrontal Cortex, Interneurons, Animals, Mice, Serotonin, Potassium Channels, Receptors, Serotonin, Electric Conductivity, Action Potentials, Models, Neurological, Optical Imaging, Gamma Rhythm, fast-spiking interneurons, mouse, neuroscience, parvalbumin interneurons, prefrontal cortex, serotonin, synaptic integration, temporal summation, Receptors, Models, Neurological, Neurosciences, Basic Behavioral and Social Science, Behavioral and Social Science, 1.1 Normal biological development and functioning, Biochemistry and Cell Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/780901khTest

المؤلفون: Ben-Shalom, Roy, Keeshen, Caroline M, Berrios, Kiara N, An, Joon Y, Sanders, Stephan J, Bender, Kevin J

المصدر: Biological Psychiatry. 82(3)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Mental Health, Pediatric, Neurodegenerative, Intellectual and Developmental Disabilities (IDD), Brain Disorders, Epilepsy, Autism, 2.1 Biological and endogenous factors, Aetiology, Neurological, Autism Spectrum Disorder, Cerebral Cortex, Computer Simulation, Epilepsy, Benign Neonatal, Genetic Predisposition to Disease, HEK293 Cells, Humans, Immunohistochemistry, Infant, Membrane Potentials, Models, Neurological, Mutation, NAV1.2 Voltage-Gated Sodium Channel, Patch-Clamp Techniques, Pyramidal Cells, Seizures, Spasms, Infantile, Autism spectrum disorder, Na(V)1.2, electrophysiology, SCN2A, Seizure, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry, Biological sciences, Biomedical and clinical sciences, Psychology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8xw6z0mcTest

المؤلفون: Yang, Sungchil, Ben-Shalom, Roy, Ahn, Misol, Liptak, Alayna T, van Rijn, Richard M, Whistler, Jennifer L, Bender, Kevin J

المصدر: Cell reports. 16(6)

مصطلحات موضوعية: Animals, Humans, Calcium, Dopamine, Calcium Channels, Receptors, G-Protein-Coupled, Phosphorylation, HEK293 Cells, beta-Arrestins, Axon Initial Segment, Biochemistry and Cell Biology

الوصول الحر: https://escholarship.org/uc/item/6410d81kTest