المؤلفون: Kairbaan Hodivala-Dilke, Melania Capasso, Frances R. Balkwill, Hemant M. Kocher, Michele Bombardieri, Sarah Spear, Francesca R. Delvecchio, Andrew Clear, Rachel Elizabeth Ann Fincham, Marina Roy-Luzarraga, John G. Gribben

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology 12(5), 1543-1565 (2021). doi:10.1016/j.jcmgh.2021.06.023
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1543-1565 (2021)

مصطلحات موضوعية: B Cells, immunology [Carcinoma, Pancreatic Ductal], immunology [Dendritic Cells], medicine.medical_treatment, PDAC, pancreatic ductal adenocarcinoma, pathology [Tertiary Lymphoid Structures], RC799-869, SLO, secondary lymphoid organ, immunology [T-Lymphocytes], Orthotopic, BMDC, bone marrow–derived dendritic cell, Mice, drug therapy [Pancreatic Neoplasms], TLS, tertiary lymphoid structures, therapeutic use [Antineoplastic Agents], Medicine, FDC, follicular dendritic cell, Original Research, Antigen Presentation, drug therapy [Tertiary Lymphoid Structures], T Cells, Gastroenterology, HEV, high endothelial venules, immunology [B-Lymphocytes], Combination chemotherapy, Diseases of the digestive system. Gastroenterology, Immunohistochemistry, pathology [B-Lymphocytes], Treatment Outcome, RT, room temperature, BCL6, B cell lymphoma 6, metabolism [Carcinoma, Pancreatic Ductal], medicine.drug, PBS, phosphate-buffered saline, Mice, Transgenic, Transgenic Mice, metabolism [Pancreatic Neoplasms], immunology [Pancreatic Neoplasms], Cell Line, Tumor, Pancreatic cancer, metabolism [Dendritic Cells], immunology [Tumor Microenvironment], TMA, tissue microarray, Animals, Humans, ddc:610, metabolism [B-Lymphocytes], CXCL13, metabolism [T-Lymphocytes], pharmacology [Antineoplastic Agents], Chemotherapy, Hepatology, business.industry, Immunity, metabolism [Cytokines], Dendritic cell, Immunotherapy, Dendritic Cells, Germinal Center, medicine.disease, Xenograft Model Antitumor Assays, drug therapy [Carcinoma, Pancreatic Ductal], Gemcitabine, Pancreatic Neoplasms, pathology [Carcinoma, Pancreatic Ductal], Disease Models, Animal, PBS-T, Tween-20 in phosphate-buffered saline, immunology [Tertiary Lymphoid Structures], Cancer research, drug effects [Tumor Microenvironment], pathology [T-Lymphocytes], business, Biomarkers, pathology [Pancreatic Neoplasms], CCL21

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbca100680dfb1efb8c0cbafa14981d0Test
http://europepmc.org/articles/PMC8529396Test

المؤلفون: Rutger H. A. Folmer, Luc van Hijfte, Marcel Scheepstra, Koen F. W. Hekking

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 160-176 (2019)

مصطلحات موضوعية: cIAP1, cellular inhibitor of apoptosis protein, BTK, Bruton's tyrosine kinase, HDAC, histone deacetylase, Review Article, PROTAC, proteolysis targeting chimeras, HTS, high-throughput screening, PI3K, phosphatidylinositol-3-kinase, VHL, Von Hippel-Lindau, Biochemistry, GST, glutathione S-transferase, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, Structural Biology, BET, bromodomain and extra-terminal, GCN5, general control nonderepressible 5, POI, protein of interest, TBK1, TANK-Binding kinase 1, CRBN, Cereblon, DC50, the compound concentration that results in 50% target protein degradation, FLT3, FMS-like tyrosine kinase-3, 0303 health sciences, biology, Chemistry, Drug discovery, ABCB1, ATP-binding cassette sub-family B member 1, Small molecule, Computer Science Applications, Cell biology, Ubiquitin ligase, AHR, aryl hydrogen receptor, FRS2, fibroblast growth factor receptor substrate 2, RIPK2, receptor-interacting serine/threonine-protein kinase 2, 030220 oncology & carcinogenesis, Proteome, AD, Alzheimer's disease, ERK1, extracellular signal-regulated kinase 1, MDM2, mouse double-minute 2 homolog, RTK, receptor tyrosine kinase, ERα, estrogen receptor alpha, TRIM24, tripartite motif-containing 24 (also known as TIF1α), Biotechnology, DHODH, Dihydroorotate dehydrogenase, lcsh:Biotechnology, Biophysics, Protein degradation, Bivalent ligand, Bcl6, B-cell lymphoma 6, CLIPTAC, click-formed proteolysis targeting chimera, PROTAC, 03 medical and health sciences, CDK9, cyclin dependent kinase 9, ERRα, estrogen-related receptor alpha, lcsh:TP248.13-248.65, Genetics, SARM, selective androgen receptor modulator, Transcription factor, PEG, polyethylene glycol, 030304 developmental biology, PLK-1, polo-like kinase 1, PCAF, P300/CBP-associated factor, Proteasome, Brd4, bromodomain 4, MetAP-2, methionine aminopeptidase-2, Chimera, ALK, anaplastic lymphoma kinase, Cereblon, CK2, Casein kinase 2, Degrader, Aβ, amyloid-β, SNIPER, specific and non-genetic IAP-dependent protein eraser, GPCR, G-protein coupled receptor, RAR, retinoic acid receptor, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55f14af58eb8c9f473abe858d099813Test
https://doi.org/10.1016/j.csbj.2019.01.006Test

المؤلفون: Bruce R. Blazar, Gregory Miller, Wei Chen, Jing Liu, Melanie S. Nyuydzefe, Geoffrey R. Hill, Katharine M. Irvine, Michelle Melino, Wayne A. Schroder, Patrick Bertolino, Kelli P. A. MacDonald, Alexandra Zanin-Zhorov, Michele W.L. Teng, Christina Nalkurthi, Andrew D. Clouston

المصدر: JHEP Reports

مصطلحات موضوعية: pSTAT3, phosphorylated signal transducer and activator of transcription, STAT3, signal transducer and activator of transcription 3, medicine.medical_treatment, AST, aspartate aminotransferase, TGF-β, transforming growth factor-beta, Chronic liver disease, TNF, tumour necrosis factor, RORγt, RAR-related orphan receptor gamma, Fibrosis, Th17, T helper 17, Immunology and Allergy, Macrophage, BMDM, bone marrow-derived macrophages, pCofilin, phosphorylated cofilin, Gastroenterology, qRT-PCR, quantitative real-time PCR, HSC, hepatic stellate cell, ECM, extracellular matrix, MMP, matrix metalloproteinase, IL-17, Cytokine, LPS, lipopolysaccharide, medicine.symptom, GC, germinal centre, ROCK2, Rho-associated kinase 2, Research Article, ROCK2 Inhibitor KD025, NASH, non-alcoholic steatohepatitis, Liver fibrosis, α-SMA, alpha smooth muscle actin, IHC, immunohistochemical, Tfh, T follicular helper, Inflammation, Col1a2, collagen type α1, Bcl6, B-cell lymphoma 6, ROCK2, Immune system, ALT, alanine aminotransferase, Internal Medicine, medicine, DR, ductular reaction, B cells, cGVHD, chronic graft-vs-host disease, pMac, peritoneal macrophages, TAA, thioacetamide, Hepatology, business.industry, Macrophages, SR, Sirius red, medicine.disease, ROCK, Rho-associated coiled-coil forming protein kinases, RAR, retinoic acid receptor, CLD, chronic liver disease, Cancer research, Therapy, HCC, hepatocellular carcinoma, business, Hepatic fibrosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d909aee919cee8dee5b9a4e06674119fTest
https://doi.org/10.1016/j.jhepr.2021.100386Test

المؤلفون: Angela Bridges, Sandrine Jayne, Jennifer Schofield, Ana Sousa Manso, Duncan S. Holmes, Xi-Ping Zhang, Larissa Lezina, Michael T. McCabe, Mark James Bamford, Anastasia Wyce, David Jonathan Hirst, Máire A. Convery, Tom Slocombe, Andrew C. Pearce, Don O. Somers, Simon D. Wagner, Paul Scott-Stevens, Ann Louise Walker, Jonathan P. Hutchinson, Constantinos Demetriou, Cassie Messenger, Melissa C. Musso, Sian Evans, Ruth C. Barber, Joanne Morley, Thomas Gobbetti

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Transcription, Genetic, SMRT, silencing mediator for retinoid or thyroid hormone receptor, Biochemistry, Immunoglobulin G, BCL6 inhibitor, immunology, SLE, systemic lupus erythematosus, Mice, hemic and lymphatic diseases, clPARP, cleaved poly(ADP-ribose) polymerase, Zinc finger, B-Lymphocytes, biology, Chemistry, autoimmunity, Zinc Fingers, BCL6, Cell biology, Proto-Oncogene Proteins c-bcl-6, GC, germinal center, DLBCL, diffuse large B-cell lymphoma, Hapten, Research Article, IgG, immunoglobulin G, lymphoma, lymphocyte, PK, pharmacokinetic, drug discovery, FBS, fetal bovine serum, Antigen, Animals, Humans, Molecular Biology, BTB, BR-C, ttk, and bab, BCL6, B-cell lymphoma 6, Thyroid hormone receptor, TNP, trinitrophenol, Germinal center, antibody response, Cell Biology, TE, target engagement, IL, interleukin, IgM, immunoglobulin M, biology.protein, CSB, cell-staining buffer, KLH, keyhole limpet hemocyanin, POZ, pox virus and zinc finger, Corepressor, Tfh, CD4+ T-cell subset follicular helper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c7e6fdf77eb69b9270c5b0a66260fcTest
https://doi.org/10.1016/j.jbc.2021.100928Test

المؤلفون: Kerkaert, JP

المساهمون: Unité 124 INSERM, Institut de Recherche sur le Cancer, Place de Verdun, 59045 Lille cedex, France

مصطلحات موضوعية: Chromosome 3, BCL6 gene, BCL6 (B-Cell Lymphoma 6) (alias), Genes Section, BCL6 protein, human, DNA-Binding Proteins, Transcription Factors, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders

العلاقة: Atlas of Genetics and Cytogenetics in Oncology and Haematology; http://AtlasGeneticsOncology.org//Genes/BCL6ID20.htmlTest; Atlas of Genetics and Cytogenetics in Oncology and Haematology; 1999, Vol. 3, N° 1; p. 4-5; http://hdl.handle.net/2042/37472Test; https://doi.org/10.4267/2042/37472Test

الإتاحة: https://doi.org/10.4267/2042/37472Test
http://hdl.handle.net/2042/37472Test