دورية أكاديمية
Prevalence of Pulmonary Embolism Among Patients With COPD Hospitalized With Acutely Worsening Respiratory Symptoms
| العنوان: | Prevalence of Pulmonary Embolism Among Patients With COPD Hospitalized With Acutely Worsening Respiratory Symptoms |
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| المؤلفون: | Couturaud, Francis, Bertoletti, Laurent, Pastre, Jean, Roy, Pierre-Marie, Le Mao, Raphael, Gagnadoux, Frédéric, Paleiron, Nicolas, Schmidt, Jeannot, Sanchez, Olivier, de Magalhaes, Elodie, Kamara, Mariam, Hoffmann, Clément, Bressollette, Luc, Nonent, Michel, Tromeur, Cécile, Salaun, Pierre-Yves, Barillot, Sophie, Gatineau, Florence, Mismetti, Patrick, Girard, Philippe, Lacut, Karine, Lemarié, Catherine, Meyer, Guy, Leroyer, Christophe |
| المساهمون: | Département de Médecine Interne et Pneumologie Brest (DMIP - Brest), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre d'Investigation Clinique - Epidémiologie Clinique CHU Saint-Etienne (CIC-EC 1408), Centre Hospitalier Universitaire de Saint-Etienne CHU Saint-Etienne (CHU ST-E)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Santé Ingénierie Biologie Saint-Etienne (SAINBIOSE), Centre Ingénierie et Santé (CIS-ENSMSE), École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom Paris (IMT)-Institut Mines-Télécom Paris (IMT)-École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom Paris (IMT)-Institut Mines-Télécom Paris (IMT)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM), The study was supported by grants from the Programme Hospitalier de Recherche Clinique (French Department of Health) |
| المصدر: | ISSN: 2380-6583. |
| بيانات النشر: | HAL CCSD American Medical Association |
| سنة النشر: | 2021 |
| المجموعة: | Université Jean Monnet – Saint-Etienne: HAL |
| مصطلحات موضوعية: | pulmonary embolism, diagnostic, algorithm, chronic obstructive pulmonary disease, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Background Information is lacking as to the management of patients with superficial venous thrombosis (SVT) whose profile has been excluded from trials, such as patients with active cancer, severe renal impairment, or pregnancy. Objectives To describe the frequency and management of SVT occurring in these situations. Methods We retrospectively analyzed the frequency, management and evolution of all patients with isolated SVT associated with either active cancer, severe renal impairment, or pregnant or postpartum women, diagnosed in 2 university hospital between January 1st, 2015 and December 31st, 2016. Results Of the 594 isolated SVTs individualized from the 7941 reports screened, 149 SVTs (105 in the upper extremity, 44 in the lower extremity) were analyzed: 94 (63%) associated with active cancer, 27 (18%) with severe renal impairment and 30 (20%) pregnant or postpartum women. SVT was treated with anticoagulant in 34 (36%) patients with cancer, 3 (11%) patients with severe renal impairment and 19 (63%) pregnant or postpartum women. At 3-month, 16 patients (10.8%) had a further venous thromboembolic event, 8 (5.4%) major bleeding, and 9 (6.1%) died. Conclusion SVT in patients with active cancer, severe renal impairment and pregnant or postpartum women represents a quarter of isolated SVTs diagnosed. Heterogeneity of treatment patterns mainly affects patients with cancer and severe renal impairment. Poor outcomes, although probably linked to morbidity, call for dedicated research in these specific situations. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | hal-04509035; https://hal.science/hal-04509035Test |
| DOI: | 10.1001/jama.2020.23567 |
| الإتاحة: | https://doi.org/10.1001/jama.2020.23567Test https://hal.science/hal-04509035Test |
| رقم الانضمام: | edsbas.1EF497DE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1001/jama.2020.23567 |
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