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1دورية أكاديمية
المؤلفون: Singh, Jay K, Hutt, Darren M, Tait, Bradley, Guy, Naihsuan C, Sivils, Jeffrey C, Ortiz, Nina R, Payan, Ashley N, Komaragiri, Shravan Kumar, Owens, Jazzmin Jovonna, Culbertson, David, Blair, Laura J, Dickey, Chad, Kuo, Szu Yu, Finley, Dan, Dyson, H Jane, Cox, Marc B, Chaudhary, Jaideep, Gestwicki, Jason E, Balch, William E
المصدر: Cell Chemical Biology. 27(3)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Urologic Diseases, Biotechnology, Cancer, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, Acquired Cognitive Impairment, Dementia, Prostate Cancer, Alzheimer's Disease, Brain Disorders, Aging, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, HEK293 Cells, HSP90 Heat-Shock Proteins, Humans, Molecular Chaperones, Molecular Structure, Protein Folding, Small Molecule Libraries, Aha1, Alzheimer disease, androgen receptor, heat shock protein 90, prostate cancer, tau, Biochemistry and cell biology, Medicinal and biomolecular chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/3k55j4vxTest
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2دورية أكاديمية
المؤلفون: Wang, Chao, Scott, Samantha M, Sun, Shuhong, Zhao, Pei, Hutt, Darren M, Shao, Hao, Gestwicki, Jason E, Balch, William E
المصدر: Human Molecular Genetics. 29(1)
مصطلحات موضوعية: Genetics, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Allosteric Regulation, Cholesterol, Cytosol, Endoplasmic Reticulum, Endosomes, Genetic Variation, HSP70 Heat-Shock Proteins, Humans, Lysosomes, Niemann-Pick C1 Protein, Niemann-Pick Disease, Type C, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/4c60d591Test
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3دورية أكاديمية
المؤلفون: Wang, Chao, Scott, Samantha M, Subramanian, Kanagaraj, Loguercio, Salvatore, Zhao, Pei, Hutt, Darren M, Farhat, Nicole Y, Porter, Forbes D, Balch, William E
المصدر: Nature communications. 10(1)
مصطلحات موضوعية: Cell Line, Tumor, Hela Cells, Endosomes, Lysosomes, Fibroblasts, Humans, Cholesterol, Regression Analysis, Normal Distribution, Epigenesis, Genetic, Structure-Activity Relationship, Homeostasis, Lipid Metabolism, Niemann-Pick Disease, Type C, Histone Deacetylase Inhibitors, Proteostasis Deficiencies, Epigenomics, Machine Learning, Niemann-Pick C1 Protein, Vorinostat, HeLa Cells, Cell Line, Tumor, Epigenesis, Genetic, Niemann-Pick Disease, Type C
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/16k6n8sdTest
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4دورية أكاديمية
المصدر: Journal of Molecular Biology. 430(18)
مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Lung, Cystic Fibrosis, Rare Diseases, Human Genome, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Congenital, Good Health and Well Being, Biomarkers, Gene Expression Profiling, Genetic Association Studies, Genetic Predisposition to Disease, Genetic Variation, Genotype, Humans, Mutation, Precision Medicine, Proteome, Proteomics, Ivacaftor, Lumacaftor, cystic fibrosis, disease-associated variants, protein interaction profile, Medicinal and Biomolecular Chemistry, Biochemistry and Cell Biology, Microbiology, Biochemistry & Molecular Biology, Biochemistry and cell biology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/78c5d480Test
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5دورية أكاديمية
المؤلفون: Hutt, Darren M, Loguercio, Salvatore, Roth, Daniela Martino, Su, Andrew I, Balch, William E
المصدر: Journal of Biological Chemistry. 293(35)
مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Rare Diseases, Genetics, Lung, Human Genome, Cystic Fibrosis, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Aetiology, Underpinning research, Generic health relevance, Cell Line, Cystic Fibrosis Transmembrane Conductance Regulator, Eukaryotic Initiation Factor-3, Humans, Mutation, Peptide Chain Initiation, Translational, Phenylalanine, Protein Folding, Protein Interaction Maps, Protein Transport, RNA Interference, RNA, Small Interfering, F508del-CFTR, cystic fibrosis, cystic fibrosis transmembrane conductance regulator, eIF3a, eukaryotic translation initiation, eukaryotic translation initiation factor 3, network hub, protein misfolding, protein translation, proteostasis, translation initiation factor, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/4kr9v5p0Test
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6دورية أكاديمية
المؤلفون: Wang, Chao, Balch, William E
المصدر: Cell Reports. 24(8)
مصطلحات موضوعية: Biological Sciences, Genetics, Biotechnology, Human Genome, Aetiology, 2.1 Biological and endogenous factors, Generic health relevance, Good Health and Well Being, Genomics, Humans, Phenotype, Spatial Analysis, AD, APP, Alzheimer's disease, CFTR, ML, PS1, SCV, VSP, amyloid precursor protein, cystic fibrosis transmembrane conductance regulator, genetic diversity, machine learning, natural selection, phenotype landscape, presenilin 1, spatial covariance, variation spatial profiling, Biochemistry and Cell Biology, Medical Physiology, Biological sciences
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/3x3434nmTest
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7دورية أكاديميةUnderstanding the host-pathogen evolutionary balance through Gaussian process modeling of SARS-CoV-2
المؤلفون: Loguercio, Salvatore, Calverley, Ben C., Wang, Chao, Shak, Daniel, Zhao, Pei, Sun, Shuhong, Budinger, G.R. Scott, Balch, William E.
المساهمون: National Institutes of Health
المصدر: Patterns ; volume 4, issue 8, page 100800 ; ISSN 2666-3899
مصطلحات موضوعية: General Decision Sciences
الإتاحة: https://doi.org/10.1016/j.patter.2023.100800Test
https://api.elsevier.com/content/article/PII:S2666389923001551?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2666389923001551?httpAccept=text/plainTest -
8دورية أكاديمية
المؤلفون: Sun, Shuhong, Wang, Chao, Zhao, Pei, Kline, Gabe M., Grandjean, Julia M.D., Jiang, Xin, Labaudiniere, Richard, Wiseman, R. Luke, Kelly, Jeffery W., Balch, William E.
المصدر: Cell Chemical Biology ; volume 30, issue 1, page 22-42.e5 ; ISSN 2451-9456
مصطلحات موضوعية: Clinical Biochemistry, Drug Discovery, Pharmacology, Molecular Biology, Molecular Medicine, Biochemistry
الإتاحة: https://doi.org/10.1016/j.chembiol.2022.12.004Test
https://api.elsevier.com/content/article/PII:S2451945622004548?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2451945622004548?httpAccept=text/plainTest -
9دورية أكاديمية
المؤلفون: Anglès, Frédéric, Gupta, Vijay, Wang, Chao, Balch, William E.
المصدر: Scientific Reports; 5/2/2024, Vol. 14 Issue 1, p1-17, 17p
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10دورية أكاديمية
المؤلفون: Budinger, GR Scott, Kohanski, Ronald A, Gan, Weiniu, Kobor, Michael S, Amaral, Luis A, Armanios, Mary, Kelsey, Karl T, Pardo, Annie, Tuder, Rubin, Macian, Fernando, Chandel, Navdeep, Vaughan, Douglas, Rojas, Mauricio, Mora, Ana L, Kovacs, Elizabeth, Duncan, Steven R, Finkel, Toren, Choi, Augustine, Eickelberg, Oliver, Chen, Danica, Agusti, Alvar, Selman, Moises, Balch, William E, Busse, Paula, Lin, Anning, Morimoto, Richard, Sznajder, Jacob I, Thannickal, Victor J
المصدر: The Journals of Gerontology Series A. 72(11)
مصطلحات موضوعية: Aging, Lung, Respiratory, Good Health and Well Being, Humans, Lung Diseases, Metabolomics, National Heart, Lung, and Blood Institute (U.S.), United States, Lungs/pulmonary, Biology of aging, Age, related pathology, Age-related pathology, Clinical Sciences, Gerontology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/54m7639dTest