المؤلفون: Valente A., Mariani J., Seminara S., Tettamanti M., Pignataro G., Perego C., Sironi L., Pedata F., Amantea D., Bacigaluppi M., Vinciguerra A., Diamanti S., Viganò M., Santangelo F., Zoia C. P., Rodriguez-Menendez V., Castiglioni L., Rzemieniec J., Dettori I., Bulli I., Coppi E., Di Santo C., Cuomo O., Gullotta G. S., Butti E., Bagetta G., Martino G., De Simoni M. G., Ferrarese C., Fumagalli S., Beretta S.

المساهمون: Valente, A., Mariani, J., Seminara, S., Tettamanti, M., Pignataro, G., Perego, C., Sironi, L., Pedata, F., Amantea, D., Bacigaluppi, M., Vinciguerra, A., Diamanti, S., Viganò, M., Santangelo, F., Zoia, C. P., Rodriguez-Menendez, V., Castiglioni, L., Rzemieniec, J., Dettori, I., Bulli, I., Coppi, E., Di Santo, C., Cuomo, O., Gullotta, G. S., Butti, E., Bagetta, G., Martino, G., De Simoni, M. G., Ferrarese, C., Fumagalli, S., Beretta, S.

مصطلحات موضوعية: Multicentre preclinical randomized controlled trials (pRCTs) are a valuable tool to improve experimental stroke research, but are challenging and therefore underused. A common challenge regards the standardization of procedures across centres. We here present the harmonization phase for the quantification of sensorimotor deficits by composite neuroscore, which was the primary outcome of two multicentre pRCTs assessing remote ischemic conditioning in rodent models of ischemic stroke. Ischemic stroke was induced by middle cerebral artery occlusion for 30, 45 or 60 min in mice and 50, 75 or 100 min in rats, allowing sufficient variability. Eleven animals per species were video recorded during neurobehavioural tasks and evaluated with neuroscore by eight independent raters, remotely and blindly. We aimed at reaching an intraclass correlation coefficient (ICC) ≥0.60 as satisfactory interrater agreement. After a first remote training we obtained ICC = 0.50 for mice and ICC = 0.49 for rats. Errors were identified in animal handling and test execution. After a second remote training, we reached the target interrater agreement for mice (ICC = 0.64) and rats (ICC = 0.69). In conclusion, a multi-step, online harmonization phase proved to be feasible, easy to implement and highly effective to align each centre’s behavioral evaluations before project’s interventional phase

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36823998; info:eu-repo/semantics/altIdentifier/wos/WOS:000935025100001; volume:43; issue:7; firstpage:1077; lastpage:1088; numberofpages:12; journal:JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM; https://hdl.handle.net/20.500.11768/158496Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85148756950

الإتاحة: https://doi.org/20.500.11768/158496Test
https://doi.org/10.1177/0271678X231159958Test
https://hdl.handle.net/20.500.11768/158496Test

المؤلفون: Rivellini, C., Porrello, E., Dina, G., Mrakic-Sposta, S., Vezzoli, A., Bacigaluppi, M., Gullotta, G., Chaabane, L., Leocani, L., Marenna, S., Colombo, E., Farina, C., Newcombe, J., Nave, K., Pardi, R., Quattrini, A., Previtali, S.

المصدر: Journal of Clinical Investigation

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/21.11116/0000-000A-6942-6Test; http://hdl.handle.net/21.11116/0000-000A-6947-1Test

الإتاحة: https://doi.org/10.1172/JCI145071Test
http://hdl.handle.net/21.11116/0000-000A-6942-6Test
http://hdl.handle.net/21.11116/0000-000A-6947-1Test

المؤلفون: Altmann A., Ryten M., Di Nunzio M., Ravizza T., Tolomeo D., Reynolds R. H., Somani A., Bacigaluppi M., Iori V., Micotti E., Di Sapia R., Cerovic M., Palma E., Ruffolo G., Botia J. A., Absil J., Alhusaini S., Alvim M. K. M., Auvinen P., Bargallo N., Bartolini E., Bender B., Bergo F. P. G., Bernardes T., Bernasconi A., Bernasconi N., Bernhardt B. C., Blackmon K., Braga B., Caligiuri M. E., Calvo A., Carlson C., Carr S. J. A., Cavalleri G. L., Cendes F., Chen J., Chen S., Cherubini A., Concha L., David P., Delanty N., Depondt C., Devinsky O., Doherty C. P., Domin M., Focke N. K., Foley S., Franca W., Gambardella A., Guerrini R., Hamandi K., Hibar D. P., Isaev D., Jackson G. D., Jahanshad N., Kalviainen R., Keller S. S., Kochunov P., Kotikalapudi R., Kowalczyk M. A., Kuzniecky R., Kwan P., Labate A., Langner S., Lenge M., Liu M., Martin P., Mascalchi M., Meletti S., Morita-Sherman M. E., O'Brien T. J., Pariente J. C., Richardson M. P., Rodriguez-Cruces R., Rummel C., Saavalainen T., Semmelroch M. K., Severino M., Striano P., Thesen T., Thomas R. H., Tondelli M., Tortora D., Vaudano A. E., Vivash L., von Podewils F., Wagner J., Weber B., Wiest R., Yasuda C. L., Zhang G., Zhang J., Leu C., Avbersek A., Thom M., Whelan C. D., Thompson P., McDonald C. R., Vezzani A., Sisodiya S. M.

المساهمون: Altmann, A., Ryten, M., Di Nunzio, M., Ravizza, T., Tolomeo, D., Reynolds, R. H., Somani, A., Bacigaluppi, M., Iori, V., Micotti, E., Di Sapia, R., Cerovic, M., Palma, E., Ruffolo, G., Botia, J. A., Absil, J., Alhusaini, S., Alvim, M. K. M., Auvinen, P., Bargallo, N., Bartolini, E., Bender, B., Bergo, F. P. G., Bernardes, T., Bernasconi, A., Bernasconi, N., Bernhardt, B. C., Blackmon, K., Braga, B., Caligiuri, M. E., Calvo, A., Carlson, C., Carr, S. J. A., Cavalleri, G. L., Cendes, F., Chen, J., Chen, S., Cherubini, A., Concha, L., David, P., Delanty, N., Depondt, C., Devinsky, O., Doherty, C. P., Domin, M., Focke, N. K., Foley, S., Franca, W., Gambardella, A., Guerrini, R., Hamandi, K., Hibar, D. P., Isaev, D., Jackson, G. D., Jahanshad, N., Kalviainen, R., Keller, S. S., Kochunov, P., Kotikalapudi, R., Kowalczyk, M. A., Kuzniecky, R., Kwan, P., Labate, A., Langner, S., Lenge, M., Liu, M., Martin, P., Mascalchi, M., Meletti, S., Morita-Sherman, M. E., O'Brien, T. J., Pariente, J. C., Richardson, M. P., Rodriguez-Cruces, R., Rummel, C., Saavalainen, T., Semmelroch, M. K., Severino, M., Striano, P., Thesen, T., Thomas, R. H., Tondelli, M., Tortora, D., Vaudano, A. E., Vivash, L., von Podewils, F., Wagner, J., Weber, B., Wiest, R., Yasuda, C. L., Zhang, G., Zhang, J., Leu, C., Avbersek, A., Thom, M., Whelan, C. D., Thompson, P., Mcdonald, C. R., Vezzani, A., Sisodiya, S. M.

مصطلحات موضوعية: cortical thinning, gene expression, MRI, post mortem

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34388852; info:eu-repo/semantics/altIdentifier/wos/WOS:000692612900001; firstpage:N/A; lastpage:N/A; journal:NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY; http://hdl.handle.net/11380/1255664Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85114315833

الإتاحة: https://doi.org/10.1111/nan.12758Test
http://hdl.handle.net/11380/1255664Test

المؤلفون: Reitmeir, R., Kilic, E., Kilic, U., Bacigaluppi, M., Elali, A., Salani, G., Hermann, D.M.

المساهمون: Reitmeir, R., Kilic, E., Kilic, U., Bacigaluppi, M., Elali, A., Salani, G., Hermann, D.M., Yeditepe Üniversitesi

مصطلحات موضوعية: axonal growth, focal cerebral ischaemia, hematopoietic growth factor, inflammation

العلاقة: Brain; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; PubMed ID: 21186263; 84; 99; 134; https://hdl.handle.net/20.500.11831/651Test

الإتاحة: https://doi.org/20.500.11831/651Test
https://hdl.handle.net/20.500.11831/651Test

المؤلفون: Altmann, A, Ryten, M, Di Nunzio, M, Ravizza, T, Tolomeo, D, Reynolds, RH, Somani, A, Bacigaluppi, M, Iori, V, Micotti, E, Di Sapia, R, Cerovic, M, Palma, E, Ruffolo, G, Botia, JA, Absil, J, Alhusaini, S, Alvim, MKM, Auvinen, P, Bargallo, N, Bartolini, E, Bender, B, Bergo, FPG, Bernardes, T, Bernasconi, A, Bernasconi, N, Bernhardt, BC, Blackmon, K, Braga, B, Caligiuri, ME, Calvo, A, Carlson, C, Carr, SJA, Cavalleri, GL, Cendes, F, Chen, J, Chen, S, Cherubini, A, Concha, L, David, P, Delanty, N, Depondt, C, Devinsky, O, Doherty, CP, Domin, M, Focke, NK, Foley, S, Franca, W, Gambardella, A, Guerrini, R, Hamandi, K, Hibar, DP, Isaev, D, Jackson, GD, Jahanshad, N, Kalviainen, R, Keller, SS, Kochunov, P, Kotikalapudi, R, Kowalczyk, MA, Kuzniecky, R, Kwan, P, Labate, A, Langner, S, Lenge, M, Liu, M, Martin, P, Mascalchi, M, Meletti, S, Morita-Sherman, ME, O'Brien, TJ, Pariente, JC, Richardson, MP, Rodriguez-Cruces, R, Rummel, C, Saavalainen, T, Semmelroch, MK, Severino, M, Striano, P, Thesen, T, Thomas, RH, Tondelli, M, Tortora, D, Vaudano, AE, Vivash, L, Podewils, F, Wagner, J, Weber, B, Wiest, R, Yasuda, CL, Zhang, G, Zhang, J, Leu, C, Avbersek, A, Thom, M, Whelan, CD, Thompson, P, McDonald, CR, Vezzani, A, Sisodiya, SM

العلاقة: Altmann, A., Ryten, M., Di Nunzio, M., Ravizza, T., Tolomeo, D., Reynolds, R. H., Somani, A., Bacigaluppi, M., Iori, V., Micotti, E., Di Sapia, R., Cerovic, M., Palma, E., Ruffolo, G., Botia, J. A., Absil, J., Alhusaini, S., Alvim, M. K. M., Auvinen, P. ,. Sisodiya, S. M. (2021). A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 48 (1), https://doi.org/10.1111/nan.12758Test.; http://hdl.handle.net/11343/289532Test

الإتاحة: https://doi.org/10.1111/nan.12758Test
http://hdl.handle.net/11343/289532Test

المؤلفون: Gullotta G. S., De Feo D., Friebel E., Semerano A., Scotti G. M., Bergamaschi A., Butti E., Brambilla E., Genchi A., Capotondo A., Gallizioli M., Coviello S., Piccoli M., Vigo T., Della Valle P., Ronchi P., Comi G., D'Angelo A., Maugeri N., Roveri L., Uccelli A., Becher B., Martino G., Bacigaluppi M.

المساهمون: Gullotta, G. S., De Feo, D., Friebel, E., Semerano, A., Scotti, G. M., Bergamaschi, A., Butti, E., Brambilla, E., Genchi, A., Capotondo, A., Gallizioli, M., Coviello, S., Piccoli, M., Vigo, T., Della Valle, P., Ronchi, P., Comi, G., D'Angelo, A., Maugeri, N., Roveri, L., Uccelli, A., Becher, B., Martino, G., Bacigaluppi, M.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37188941; info:eu-repo/semantics/altIdentifier/wos/WOS:000987977400003; volume:24; issue:6; firstpage:925; lastpage:940; numberofpages:16; journal:NATURE IMMUNOLOGY; https://hdl.handle.net/20.500.11768/159579Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85159377050; https://www.nature.com/articles/s41590-023-01505-1Test

الإتاحة: https://doi.org/20.500.11768/159579Test
https://doi.org/10.1038/s41590-023-01505-1Test
https://hdl.handle.net/20.500.11768/159579Test
https://www.nature.com/articles/s41590-023-01505-1Test

المؤلفون: Semerano, A., Strambo, D., Martino, G., Comi, G., Filippi, M., Roveri, L., Bacigaluppi, M.

المصدر: Frontiers in neurology, vol. 11, pp. 201

مصطلحات موضوعية: infection, ischemic stroke, leukocytes, neutrophil to lymphocyte ratio, outcome

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32308640; info:eu-repo/semantics/altIdentifier/pissn/1664-2295; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_E80C34CDDA093; https://serval.unil.ch/notice/serval:BIB_E80C34CDDA09Test; urn:issn:1664-2295; https://serval.unil.ch/resource/serval:BIB_E80C34CDDA09.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E80C34CDDA093Test

الإتاحة: https://doi.org/10.3389/fneur.2020.00201Test
https://serval.unil.ch/notice/serval:BIB_E80C34CDDA09Test
https://serval.unil.ch/resource/serval:BIB_E80C34CDDA09.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E80C34CDDA093Test

المؤلفون: Ministrini, S, Puspitasari, Y M, Beer, G, Schwarz, L, Niederberger, R, Kraler, S, Akhmedov, A, Katan, M, Bacigaluppi, M, Montecucco, F, Luescher, T F, Camici, G, Liberale, L

المصدر: European Heart Journal ; volume 44, issue Supplement_2 ; ISSN 0195-668X 1522-9645

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1093/eurheartj/ehad655.3274Test
https://academic.oup.com/eurheartj/article-pdf/44/Supplement_2/ehad655.3274/53590965/ehad655.3274.pdfTest

المؤلفون: Genchi A., Semerano A., Schwarz G., Dell'Acqua B., Gullotta G. S., Sampaolo M., Boeri E., Quattrini A., Sanvito F., Diamanti S., Bergamaschi A., Grassi S., Podini P., Panni P., Michelozzi C., Simionato F., Scomazzoni F., Remida P., Valvassori L., Falini A., Ferrarese C., Michel P., Saliou G., Hajdu S., Beretta S., Roveri L., Filippi M., Strambo D., Martino G., Bacigaluppi M.

المساهمون: Genchi, A, Semerano, A, Schwarz, G, Dell'Acqua, B, Gullotta, G, Sampaolo, M, Boeri, E, Quattrini, A, Sanvito, F, Diamanti, S, Bergamaschi, A, Grassi, S, Podini, P, Panni, P, Michelozzi, C, Simionato, F, Scomazzoni, F, Remida, P, Valvassori, L, Falini, A, Ferrarese, C, Michel, P, Saliou, G, Hajdu, S, Beretta, S, Roveri, L, Filippi, M, Strambo, D, Martino, G, Bacigaluppi, M

مصطلحات موضوعية: COVID-19, Endovascular treatment, Ischemic stroke, Neutrophil, SARS-CoV2, Thrombosi

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35105380; info:eu-repo/semantics/altIdentifier/wos/WOS:000749526200001; volume:10; issue:1 (December 2022); journal:ACTA NEUROPATHOLOGICA COMMUNICATIONS; http://hdl.handle.net/10281/362595Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85123973471

الإتاحة: https://doi.org/10.1186/s40478-022-01313-yTest
http://hdl.handle.net/10281/362595Test

المؤلفون: Altmann A., Ryten M., Di Nunzio M., Ravizza T., Tolomeo D., Reynolds R. H., Somani A., Bacigaluppi M., Iori V., Micotti E., Di Sapia R., Cerovic M., Palma E., Ruffolo G., Botia J. A., Absil J., Alhusaini S., Alvim M. K. M., Auvinen P., Bargallo N., Bartolini E., Bender B., Bergo F. P. G., Bernardes T., Bernasconi A., Bernasconi N., Bernhardt B. C., Blackmon K., Braga B., Caligiuri M. E., Calvo A., Carlson C., Carr S. J. A., Cavalleri G. L., Cendes F., Chen J., Chen S., Cherubini A., Concha L., David P., Delanty N., Depondt C., Devinsky O., Doherty C. P., Domin M., Focke N. K., Foley S., Franca W., Gambardella A., Guerrini R., Hamandi K., Hibar D. P., Isaev D., Jackson G. D., Jahanshad N., Kalviainen R., Keller S. S., Kochunov P., Kotikalapudi R., Kowalczyk M. A., Kuzniecky R., Kwan P., Labate A., Langner S., Lenge M., Liu M., Martin P., Mascalchi M., Meletti S., Morita-Sherman M. E., O'Brien T. J., Pariente J. C., Richardson M. P., Rodriguez-Cruces R., Rummel C., Saavalainen T., Semmelroch M. K., Severino M., Striano P., Thesen T., Thomas R. H., Tondelli M., Tortora D., Vaudano A. E., Vivash L., von Podewils F., Wagner J., Weber B., Wiest R., Yasuda C. L., Zhang G., Zhang J., Leu C., Avbersek A., Thom M., Whelan C. D., Thompson P., McDonald C. R., Vezzani A., Sisodiya S. M.

المساهمون: Altmann, A., Ryten, M., Di Nunzio, M., Ravizza, T., Tolomeo, D., Reynolds, R. H., Somani, A., Bacigaluppi, M., Iori, V., Micotti, E., Di Sapia, R., Cerovic, M., Palma, E., Ruffolo, G., Botia, J. A., Absil, J., Alhusaini, S., Alvim, M. K. M., Auvinen, P., Bargallo, N., Bartolini, E., Bender, B., Bergo, F. P. G., Bernardes, T., Bernasconi, A., Bernasconi, N., Bernhardt, B. C., Blackmon, K., Braga, B., Caligiuri, M. E., Calvo, A., Carlson, C., Carr, S. J. A., Cavalleri, G. L., Cendes, F., Chen, J., Chen, S., Cherubini, A., Concha, L., David, P., Delanty, N., Depondt, C., Devinsky, O., Doherty, C. P., Domin, M., Focke, N. K., Foley, S., Franca, W., Gambardella, A., Guerrini, R., Hamandi, K., Hibar, D. P., Isaev, D., Jackson, G. D., Jahanshad, N., Kalviainen, R., Keller, S. S., Kochunov, P., Kotikalapudi, R., Kowalczyk, M. A., Kuzniecky, R., Kwan, P., Labate, A., Langner, S., Lenge, M., Liu, M., Martin, P., Mascalchi, M., Meletti, S., Morita-Sherman, M. E., O'Brien, T. J., Pariente, J. C., Richardson, M. P., Rodriguez-Cruces, R., Rummel, C., Saavalainen, T., Semmelroch, M. K., Severino, M., Striano, P., Thesen, T., Thomas, R. H., Tondelli, M., Tortora, D., Vaudano, A. E., Vivash, L., von Podewils, F., Wagner, J., Weber, B., Wiest, R., Yasuda, C. L., Zhang, G., Zhang, J., Leu, C., Avbersek, A., Thom, M., Whelan, C. D., Thompson, P., Mcdonald, C. R., Vezzani, A., Sisodiya, S. M.

مصطلحات موضوعية: cortical thinning, gene expression, MRI, post mortem

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000692612900001; volume:48; issue:1; firstpage:1; lastpage:15; numberofpages:15; journal:NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY; http://hdl.handle.net/11570/3231637Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85114315833

الإتاحة: https://doi.org/10.1111/nan.12758Test
http://hdl.handle.net/11570/3231637Test