المؤلفون: Zhang Zheng, Liu Yuxin, Xu Yaolin, Xu Zijin, Jia Jinbin, Jin Yun, Wang Wenquan, Liu Liang

المصدر: Acta Biochimica et Biophysica Sinica, Vol 56, Pp 576-585 (2024)

مصطلحات موضوعية: pancreatic cancer, wild-type BRCA, BRCAness, KLF5, BRCA1, Biochemistry, QD415-436, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1672-9145Test

الوصول الحر: https://doaj.org/article/9fd6357d291e4d788b1a10b4f86109a7Test

المؤلفون: Martina Arcieri, Veronica Tius, Claudia Andreetta, Stefano Restaino, Anna Biasioli, Elena Poletto, Giuseppe Damante, Alfredo Ercoli, Lorenza Driul, Anna Fagotti, Domenica Lorusso, Giovanni Scambia, Giuseppe Vizzielli

المصدر: Frontiers in Oncology, Vol 14 (2024)

مصطلحات موضوعية: ovarian cancer, homologous recombination deficiency, BRCA protein, BRCAness, HRD testing, PARP inhibitors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fonc.2024.1335196/fullTest; https://doaj.org/toc/2234-943XTest

الوصول الحر: https://doaj.org/article/3d1bed078930434ca0103b78ab067442Test

المؤلفون: Orhan, Esin, Velazquez, Carolina, Tabet, Imene, Fenou, Lise, Rodier, Geneviève, Orsetti, Béatrice, Jacot, William, Sardet, Claude, Theillet, Charles

المساهمون: Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), This work benefited from the following financial support: Astra-Zeneca contract # 2018-02069, Institut National du Cancer PRTK-2017 MODUREPOIS, Ligue Nationale Contre le Cancer ‘Comité régional Occitanie-Est’ 2021-R22031FF and the SIRIC Montpellier Cancer Grant INCa-DGOS-Inserm_12553.

المصدر: ISSN: 0304-3835 ; Cancer Letters ; https://hal.umontpellier.fr/hal-04535765Test ; Cancer Letters, 2024, 589, pp.216820. ⟨10.1016/j.canlet.2024.216820⟩.

مصطلحات موضوعية: BRCA1, TNBC, HRD, CDK9/12-inhibitor, pharmacologic-BRCAness, pharmacologic-BRCAness. Highlights BRCA1-WT, BRCA1 wild type gene BRCAness, BRCA-deficiency CDK, Cyclin Dependent Kinase CDKi, CDK inhibitors CDDP, cisplatin CTD, carboxy terminal domain DSB, double strand DNA break HRD, homologous recombination deficient or deficiency IC50, median inhibitory concentration PARPi, PARP inhibitor PDX, patient derived tumor xenograft TNBC, Triple Negative Breast Cancer, BRCA1 wild type gene, BRCAness, BRCA-deficiency, CDK, Cyclin Dependent Kinase, CDKi, CDK inhibitors, CDDP, cisplatin, CTD, carboxy terminal domain, DSB

العلاقة: hal-04535765; https://hal.umontpellier.fr/hal-04535765Test; https://hal.umontpellier.fr/hal-04535765/documentTest; https://hal.umontpellier.fr/hal-04535765/file/MS%20CDKi_ola-cancer%20280324-unmarked.pdfTest

الإتاحة: https://doi.org/10.1016/j.canlet.2024.216820Test
https://hal.umontpellier.fr/hal-04535765Test
https://hal.umontpellier.fr/hal-04535765/documentTest
https://hal.umontpellier.fr/hal-04535765/file/MS%20CDKi_ola-cancer%20280324-unmarked.pdfTest

المؤلفون: Yuting Qu, Sisi Qin, Zhihui Yang, Zhuolin Li, Qinhao Liang, Ting Long, Weiyun Wang, Dan Zeng, Qing Zhao, Zehua Dai, Qing Ni, Fei Zhao, Wootae Kim, Jing Hou

المصدر: Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115877- (2023)

مصطلحات موضوعية: Breast cancer, DNA damage, BRCA1/2 mutation, PARP inhibitor, BRCAness, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S075333222301675XTest; https://doaj.org/toc/0753-3322Test

الوصول الحر: https://doaj.org/article/36a25e3c4bb440cfb9fbea8bddf4f416Test

المؤلفون: Jay, Ash, Reitz, Diedre, Namekawa, Satoshi H, Heyer, Wolf-Dietrich

مصطلحات موضوعية: Biological Sciences, Genetics, Human Genome, Cancer, Biotechnology, DNA Breaks, Double-Stranded, DNA Repair, Genomic Instability, Homologous Recombination, Humans, Male, Neoplasms, Testis, BRCAness, Homologous recombination, Meiosis, Poly (ADP-ribose) polymerase inhibition, Replication fork protection, Biochemistry and Cell Biology, Developmental Biology, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4rf6627kTest
https://escholarship.org/content/qt4rf6627k/qt4rf6627k.pdfTest

المؤلفون: Masanori Oshi, Shipra Gandhi, Rongrong Wu, Mariko Asaoka, Li Yan, Akimitsu Yamada, Shinya Yamamoto, Kazutaka Narui, Takashi Chishima, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe

المصدر: Biomarker Research, Vol 10, Iss 1, Pp 1-11 (2022)

مصطلحات موضوعية: Breast cancer, BRCAness, Gene expression, Signaling, Biomarker, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2050-7771Test

الوصول الحر: https://doaj.org/article/5017b9300635441caab79d7ab54c3fe7Test

المؤلفون: Farzaneh Darbeheshti, Sepideh Kadkhoda, Mahsa Keshavarz-Fathi, Sepideh Razi, Afshin Bahramy, Yaser Mansoori, Nima Rezaei

المصدر: BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Breast cancer, Triple-negative, BRCAness, miRNAs, Cell-free biomarker, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1471-2407Test

الوصول الحر: https://doaj.org/article/804416d74d9948aea4860378b970df2cTest

المؤلفون: Keung, Man Yee T, Wu, Yanyuan, Vadgama, Jaydutt V

المصدر: Journal of clinical medicine. 8(4)

مصطلحات موضوعية: BRCA, BRCAness, PARP, PARP inhibitors, biomarkers, breast cancer, resistance, Clinical Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8442h008Test

المؤلفون: O'Sullivan Coyne G, Karlovich C, Wilsker D, Voth AR, Parchment RE, Chen AP, Doroshow JH

المصدر: OncoTargets and Therapy, Vol Volume 15, Pp 165-180 (2022)

مصطلحات موضوعية: next-generation sequencing, genomic scar, mutational signature, rad51, brcaness, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/parp-inhibitor-applicability-detailed-assays-for-homologous-recombinat-peer-reviewed-fulltext-article-OTTTest; https://doaj.org/toc/1178-6930Test

الوصول الحر: https://doaj.org/article/3be61c77e444446294bde147fd416febTest

المؤلفون: Andersen, Lars V B, Larsen, Martin J, Davies, Helen, Degasperi, Andrea, Nielsen, Henriette Roed, Jensen, Louise A, Kroeldrup, Lone, Gerdes, Anne-Marie, Lænkholm, Anne-Vibeke, Kruse, Torben A, Nik-Zainal, Serena, Thomassen, Mads

المصدر: Andersen , L V B , Larsen , M J , Davies , H , Degasperi , A , Nielsen , H R , Jensen , L A , Kroeldrup , L , Gerdes , A-M , Lænkholm , A-V , Kruse , T A , Nik-Zainal , S & Thomassen , M 2023 , ' Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness ' , Breast Cancer Research , vol. 25 , 69 . https://doi.org/10.1186/s13058-023-01655-yTest

مصطلحات موضوعية: Humans, Female, Genes, BRCA2, Breast Neoplasms/epidemiology, Prevalence, Mutation, BRCA2 Protein/genetics, Whole genome sequencing, Breast cancer, Hereditary breast cancer, BRCAness, HRDetect, Non-BRCA1/BRCA2, Mutational signatures

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/e42eae56-b6d8-4d54-9906-771fdf50a082Test

الإتاحة: https://doi.org/10.1186/s13058-023-01655-yTest
https://portal.findresearcher.sdu.dk/da/publications/e42eae56-b6d8-4d54-9906-771fdf50a082Test
https://findresearcher.sdu.dk/ws/files/233416755/s13058_023_01655_y.pdfTest