المؤلفون: Steven J. Fliesler, Sriganesh Ramachandra Rao, Sithara Raju Ponny, Ned A. Porter, Shailendra B. Patel, Vincent Fong, Babu Nageswararao Kanuri, Keri A. Tallman

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100002-(2021)
Journal of Lipid Research

مصطلحات موضوعية: 0301 basic medicine, LC-MS, liquid chromatography-mass spectrometry, dHLan, 24-dihydrolanosterol, 14d-Zyme, 14-dehydrozymostenol, 7-DHC, 7-dehydrocholesterol, 030204 cardiovascular system & hematology, SREBF1/2, sterol regulatory element binding transcription factor half, PPARA, peroxisome proliferator activated receptor alpha, Biochemistry, LKO, liver-specific knockout, LDLR, low density lipoprotein receptor, 0302 clinical medicine, Endocrinology, CYP27A1, Conditional gene knockout, CEACAM1, carcinoembryonic antigen-related cell adhesion molecule 1, Glucose homeostasis, DMAP, 4-dimethylaminopyridine, FDFT1, Farnesyl-diphosphate farnesyl transferase 1, 7-dehydrocholesterol, GEO, Gene Expression Omnibus, SRM, selected reaction monitoring, PPh3, triphenylphosphine, NR1H2/3/4/5, nuclear receptor subfamily 1 group H member 2/3/4/5, 14d-Zym, 14-dehydrozymosterol, ESI, electrospray ionization, Chol, cholesterol, MTTP, microsomal triglyceride transfer protein, dysmorphology, SCARB1, scavenger receptor class B member 1, CYP7A1, cytochrome P450 family 7 subfamily A member 1, FAS, fatty acid synthase, HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase, Lan, lanosterol, TPM, transcript per million, 7-DHD, 7-dehydrodesmosterol, Knockout mouse, GTT, glucose tolerance test, IACUC, institutional animal care and use committee, Research Article, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, LIPC, hepatic triacylglycerol lipase, CHCl3, trichloromethane, CYP8B1, cytochrome P450 family 8 subfamily B member 1, Et3N, triethylamine, PPARG, peroxisome proliferator activated receptor gamma, ABCB11, ATP binding cassette subfamily B member 11, QD415-436, Biology, Cholesterol 7 alpha-hydroxylase, CD36, cluster of differentiation 36, CYP27A1, cytochrome P450 family 27 subfamily A member 1, ABCG1/5/8, ATP binding cassette subfamily G member 1/5/8, DHCR7, 3β-hydroxysterol-Δ7 reductase, Des, desmosterol, 03 medical and health sciences, Smith-Lemli-Opitz syndrome, Zyme, zymostenol, Internal medicine, DHCR24, 3β-hydroxysterol-Δ24 reductase, medicine, Lath, lathosterol, Liver X receptor, BHT, 2,6-di-tert-butyl-4-methylphenol, 8-DHC, 8-dehydrocholesterol, ITT, insulin tolerance test, UPLC, ultra performance liquid chromatography, ES, embryonic stem, Zym, zymosterol, Cell Biology, medicine.disease, SCARB1, 030104 developmental biology, Smith–Lemli–Opitz syndrome, ABCA1, ATP binding cassette subfamily A member 1, cholesterol synthesis, DMG, dimethylglycine, DHL, 24-dehydrolathosterol, SLOS, Smith-Lemli-Opitz syndrome, APO, apolipoprotein, LXR, liver X receptor, PCSK9, proprotein convertase subtilisin/kexin type 9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628669fe15a4d77e5ef7fd0fbdf15f34Test
http://www.sciencedirect.com/science/article/pii/S0022227520437046Test

المؤلفون: E. Neil G. Marsh, Ayesha M. Patel, James Windak, Robert T. Kennedy, Youngsoo Kim, Keerthi Sajja, Alexey I. Nesvizhskii, Timothy J. Grunkemeyer, Soumi Ghosh, Venkatesha Basrur

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, DAVID, Database for Annotation, Visualization and Integrated Discovery, Biochemistry, Cell membrane, radical SAM enzyme, Intramolecular Transferases, Lipid raft, biology, Chemistry, ddhCTP, 3’-deoxy-3’,4’-didehydro-CTP, Transfection, SAINT, Significance Analysis of INTeractome, Cell biology, Cholesterol, medicine.anatomical_structure, viperin, Virus Inhibitory Protein, Endoplasmic Reticulum-associated, Interferon iNducible, Viperin, cholesterol regulation, viperin, Research Article, FPPS, farnesyl pyrophosphate synthase, Protein Binding, Oxidoreductases Acting on CH-CH Group Donors, Cytidine Triphosphate, BIBB 515, (1-(4-chlorobenzoyl)-4-((4-(2-oxazolin-2-yl) benzylidene))piperidine), Antiviral Agents, ER, endoplasmic reticulum, 03 medical and health sciences, Downregulation and upregulation, medicine, Humans, IFN, interferon, Molecular Biology, BHT, 2,6-di-tert-butyl-4-methylphenol, PEI, polyethyleneimine, HMGR, 3-hydroxy-3-methylglutaryl CoA reductase, 030102 biochemistry & molecular biology, Endoplasmic reticulum, HEK 293 cells, LS, lanosterol synthase, Proteins, Cell Biology, squalene monooxygenase, HEK293T, human embryonic kidney 293T, Biosynthetic Pathways, TBS, Tris-buffered saline, HEK293 Cells, 030104 developmental biology, biology.protein, interactome analysis, UPLC, ultra performance LC, RSV, respiratory syncytial virus, SM, squalene monooxygenase, lanosterol synthase, TRAF6, TNF receptor–associated factor 6, Lanosterol synthase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29fc9694a264e3862b0e6cfaac455c5Test
https://doi.org/10.1016/j.jbc.2021.100824Test