المؤلفون: Jan Haviernik, Ludek Eyer, Antoine Nougairède, Marie Uhlířová, Jean-Sélim Driouich, Darina Zouharová, James Jason Valdés, Ernest Gould, Erik De Clercq, Xavier de Lamballerie, Daniel Ruzek

المصدر: Proceedings, Vol 50, Iss 12, p 12 (2020)

مصطلحات موضوعية: BCX4430, attenuation, drug resistance, galidesivir, mutation, tick-borne encephalitis virus, General Works

العلاقة: https://www.mdpi.com/2504-3900/50/1/12Test; https://doaj.org/toc/2504-3900Test; https://doaj.org/article/6e3341d7d4ed4d5187eeb0abbf4af128Test

الإتاحة: https://doi.org/10.3390/proceedings2020050012Test
https://doaj.org/article/6e3341d7d4ed4d5187eeb0abbf4af128Test

المؤلفون: Bouton, Jakob, Van Hecke, Kristof, Van Calenbergh, Serge

المصدر: TETRAHEDRON ; ISSN: 0040-4020

مصطلحات موضوعية: Chemistry, Nucleoside, Azanucleoside, Homonucleoside, Iminosugar, Transition state analogue, STATE ANALOG INHIBITORS, PROTOZOAN NUCLEOSIDE HYDROLASES, 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, HELICOBACTER-PYLORI, ANTIVIRAL ACTIVITY, PROTECTION, MITSUNOBU, BCX4430

وصف الملف: application/pdf

العلاقة: https://biblio.ugent.be/publication/8542025Test; http://hdl.handle.net/1854/LU-8542025Test; http://dx.doi.org/10.1016/j.tet.2017.05.083Test; https://biblio.ugent.be/publication/8542025/file/8542029Test

الإتاحة: https://doi.org/10.1016/j.tet.2017.05.083Test
https://biblio.ugent.be/publication/8542025Test
http://hdl.handle.net/1854/LU-8542025Test
https://biblio.ugent.be/publication/8542025/file/8542029Test

المؤلفون: Y.S. Babu, Amanda Mathis, Justin G. Julander, Brian B. Gowen, Dennis M. Walling, Ray Taylor, James F. Demarest

المصدر: Antiviral Research

مصطلحات موضوعية: RNA viruses, Adenosine, Pyrrolidines, Nucleoside analog, viruses, Drug Evaluation, Preclinical, BCX4430, Antiviral Agents, Article, Marburg virus, Marburg virus disease, Virology, medicine, Animals, Rift Valley fever, Antiviral, Pharmacology, biology, Clinical Trials, Phase I as Topic, business.industry, SARS-CoV-2, Adenine, Yellow fever, Nucleosides, medicine.disease, Marburgvirus, biology.organism_classification, Cell culture, Viral disease, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8044fd2740768fa2b3a0c64e5575495cTest
https://pubmed.ncbi.nlm.nih.gov/34551346Test

المؤلفون: Eric J. Sefing, Brady T. Hickerson, Kie-Hoon Jung, Amanda Mathis, Brian B. Gowen, Kevin W. Bailey, Luci Wandersee, William P. Sheridan, Ray Taylor, Jonna B. Westover

المصدر: Antiviral Research. 156:38-45

مصطلحات موضوعية: 0301 basic medicine, Adenosine, Pyrrolidines, Rift Valley Fever, medicine.drug_class, 030106 microbiology, Hamster, Spleen, BCX4430, Antiviral Agents, Injections, Intramuscular, Article, Viral hemorrhagic fever, 03 medical and health sciences, Virology, Animals, Medicine, Pathogen, Virus classification, Pharmacology, Mesocricetus, biology, business.industry, Adenine, Purine Nucleosides, Rift Valley fever virus, biology.organism_classification, medicine.disease, Survival Analysis, Disease Models, Animal, Treatment Outcome, 030104 developmental biology, medicine.anatomical_structure, Liver, Phlebovirus, Antiviral drug, business, Injections, Intraperitoneal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018c3c81857b55e37bb8c63f196f82c5Test
https://doi.org/10.1016/j.antiviral.2018.05.013Test

المؤلفون: Eyer, Ludek, Nougairede, Antoine, Uhlířová, Marie, Driouich, Jean-Sélim, Zouharová, Darina, Valdés, James, Haviernik, Jan, Gould, Ernest, Andrew, de Clercq, Erik, de Lamballerie, Xavier, Ruzek, Daniel

المساهمون: Department of Virology Brno, Czech Republic, Veterinary Research Institute Brno (VRI), Institute of Parasitology Ceske Budejovice, Czech Republic, Biology Centre of the Czech Academy of Sciences (BIOLOGY CENTRE CAS), Czech Academy of Sciences Prague (CAS)-Czech Academy of Sciences Prague (CAS), Unité des Virus Emergents (UVE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rega Institute of Medical Research Leuven, Belgium, Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), This study was supported by a grant from the Ministry of Education, Youth, and Sports of the Czech Republic (grant LTAUSA18016) (to L.E.), by a grant from the Ministry of Health of the Czech Republic (grant 16-34238A), and by Project FIT (Pharmacology, Immunotherapy, Nanotoxicology, CZ.02.1.01/0.0/0.0/15_003/0000495) from the Ministry of Education, Youth, and Sports of the Czech Republic and the Ministry of Agriculture of the Czech Republic (RO0518) (both to D.R.).

المصدر: ISSN: 0022-538X.

مصطلحات موضوعية: BCX4430, attenuation, drug resistance, galidesivir, mutation, tick-borne encephalitis virus, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31142664; inserm-02315654; https://inserm.hal.science/inserm-02315654Test; https://inserm.hal.science/inserm-02315654/documentTest; https://inserm.hal.science/inserm-02315654/file/Journal%20of%20Virology-2019-Eyer-e00367-19.full.pdfTest; PUBMED: 31142664; PUBMEDCENTRAL: PMC6675905

الإتاحة: https://doi.org/10.1128/JVI.00367-19Test
https://inserm.hal.science/inserm-02315654Test
https://inserm.hal.science/inserm-02315654/documentTest
https://inserm.hal.science/inserm-02315654/file/Journal%20of%20Virology-2019-Eyer-e00367-19.full.pdfTest

المؤلفون: Serge Van Calenbergh, Jakob Bouton, Kristof Van Hecke

المصدر: Tetrahedron
TETRAHEDRON

مصطلحات موضوعية: 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, Transition state analogue, Stereochemistry, Homonucleoside, Iminosugar, 010402 general chemistry, Ring (chemistry), 01 natural sciences, Biochemistry, Article, Pyrrolidine, Nucleobase, chemistry.chemical_compound, Ring-closing metathesis, PROTOZOAN NUCLEOSIDE HYDROLASES, HELICOBACTER-PYLORI, Drug Discovery, BCX4430, Nucleoside, PROTECTION, 010405 organic chemistry, Organic Chemistry, ANTIVIRAL ACTIVITY, 0104 chemical sciences, Chemistry, STATE ANALOG INHIBITORS, chemistry, Dihydroxylation, Azanucleoside, Mitsunobu reaction, MITSUNOBU

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4f7096c6c4d8bba6919d54edd115beTest
https://doi.org/10.1016/j.tet.2017.05.083Test

المؤلفون: Travis K. Warren, Karen A. Martins, Sina Bavari, Ronald B. Reisler, Anthony P. Cardile

المصدر: Annual Review of Pharmacology and Toxicology. 57:329-348

مصطلحات موضوعية: 0301 basic medicine, Adenosine, Pyrrolidines, Convalescent plasma, viruses, Brincidofovir, BCX4430, Favipiravir, ZMapp, Toxicology, medicine.disease_cause, Antiviral Agents, Disease Outbreaks, Food and drug administration, 03 medical and health sciences, medicine, Animals, Humans, Pharmacology, Alanine, Ebola virus, business.industry, Adenine, virus diseases, Outbreak, Purine Nucleosides, Hemorrhagic Fever, Ebola, Ribonucleotides, Ebolavirus, Virology, Adenosine Monophosphate, Africa, Western, 030104 developmental biology, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f04c3b32f18b8d875dd4f1e16031a47Test
https://doi.org/10.1146/annurev-pharmtox-010716-105055Test

المؤلفون: Venkatraman Siddharthan, Justin G. Julander, Makda S. Gebre, Preston A. Collins, William P. Sheridan, Y.S. Babu, Young-Min Lee, Jason Stewart, Skot Neilson, Kelsey Tolbert, John D. Morrey, Ray Taylor, Chad Apuli, Joe Evans, Arnaud J. Van Wettere

المصدر: Antiviral Research. 137:14-22

مصطلحات موضوعية: Male, 0301 basic medicine, Adenosine, Pyrrolidines, viruses, 030106 microbiology, Viremia, BCX4430, Biology, Virus Replication, Antiviral Agents, Article, Virus, Cell Line, Zika virus, Mice, 03 medical and health sciences, Virology, Testis, medicine, Animals, Humans, Cytopathic effect, Pharmacology, Zika Virus Infection, Adenine, Brain, Purine Nucleosides, Zika Virus, Viral Load, biology.organism_classification, medicine.disease, Disease Models, Animal, Flavivirus, 030104 developmental biology, Viral replication, Immunology, RNA, Viral, Viral load

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0fe08af59e2b527ba2b7481911496Test
https://doi.org/10.1016/j.antiviral.2016.11.003Test

المؤلفون: Sandra E. Reznik, Amit K. Tiwari, Charles R. Ashby

المصدر: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)

مصطلحات موضوعية: Pharmacology, Opinion, RNA virus, biology, Sofosbuvir, Chemistry, lcsh:RM1-950, RNA-dependent RNA polymerase, BCX4430, biology.organism_classification, Virology, sofosbuvir, RNA dependent RNA polymerase, 03 medical and health sciences, 0302 clinical medicine, lcsh:Therapeutics. Pharmacology, Ebola, medicine, 030211 gastroenterology & hepatology, Pharmacology (medical), 030212 general & internal medicine, triphosphate metabolite, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c409c84fdda8efdae956b7cef469079Test
http://europepmc.org/articles/PMC6192451Test

المؤلفون: Erik De Clercq

المصدر: Biochemical Pharmacology

مصطلحات موضوعية: Chloroquine (PubChem CID: 2719), VSV (vesicular stomatitis virus), 3-Deazaneplanocin A, viruses, Filoviridae, BCX4430, Favipiravir, medicine.disease_cause, Biochemistry, 3-Deazaneplanocin A (PubChem CID: 73087), Antiviral Agents, Virus, Article, Sierra leone, Clomifene (PubChem CID: 1548953), Viral entry, NSC62914 (PubChem CID: 66662), medicine, Animals, Humans, Favipiravir (PubChem CID: 492405), Verapamil (PubChem CID: 2520), Dronedarone (PubChem CID: 208898), ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, dUY11 (PubChem CID: 24771429), Ebola virus, biology, Chemistry, Hemorrhagic Fever, Ebola, biology.organism_classification, Ebolavirus, Virology, Africa, Western, Vesicular stomatitis virus, Ebola, LJ 001 (PubChem CID: 49777349), Amiodarone (PubChem CID: 2157), BCX4430 (PubChem CID: 69211190), BCX-1777 (PubChem CID: 11493192), FGI-103 (PubChem CID: 5477931)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51394a54405c7b2f347c815bc74ac32bTest
http://europepmc.org/articles/PMC7110990Test