يعرض 1 - 10 نتائج من 20 نتيجة بحث عن '"BCL-XL, B-cell lymphoma extra-large"', وقت الاستعلام: 1.31s تنقيح النتائج
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    دورية أكاديمية
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    دورية أكاديمية

    المساهمون: Jawaharlal Nehru Technological University, Hyderabad 500085, India (JNTU), Osmania University, Plate-forme ImPACcell (ImPACcell), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre de Recherche en Cancérologie Nantes-Angers (CRCNA), Université d'Angers (UA)-Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), CRLCC René Gauducheau, CSIR Indian Institute of Chemical Technology (IICT), Institut des Sciences Chimiques de Rennes (ISCR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Bioprojet-Biotech, Financial support by the “Ligue contre le Cancer, Conseil Interrégional Grand Ouest” is gratefully acknowledged.

    المصدر: ISSN: 0960-894X ; Bioorganic and Medicinal Chemistry Letters ; https://hal.science/hal-03414697Test ; Bioorganic and Medicinal Chemistry Letters, 2021, 52, pp.128390. ⟨10.1016/j.bmcl.2021.128390⟩.

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    المصدر: Acta Pharmaceutica Sinica. B
    Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)

    مصطلحات موضوعية: LOX1, lectin-like oxidized LDL receptor 1, BUN, blood urea nitrogen, TGBM, thickness of glomerular basement membrane, NQO1, NAD(P)H:quinone oxidoreductase 1, STAT, signal transducers and activators of transcription, N/O, not observed, p62, sequestosome 1 protein, p-IRS1, phospho-IRS1, Review, NOX-4, nicotinamide adenine dinucleotide phosphate-oxidase-4, OCP, oxidative carbonyl protein, Traditional Chinese medicine, AGEs, advanced glycation end-products, N/A, not applicable, TRAF5, tumor-necrosis factor receptor-associated factor 5, Health problems, 0302 clinical medicine, ESRD, end-stage renal disease, LDL, low-density lipoprotein, BMP-7, bone morphogenetic protein-7, TGFβR-I/II, TGF-β receptor I/II, Medicine, P70S6K, 70-kDa ribosomal protein S6 kinase, General Pharmacology, Toxicology and Pharmaceutics, SOCS, suppressor of cytokine signaling proteins, HO-1, heme oxygenase-1, 0303 health sciences, TG, triglyceride, BW, body weight, HDL-C, high density lipoprotein-cholesterol, RASI, renin-angiotensin system inhibitor, ATK, protein kinase B, TBARS, thiobarbituric acid-reactive substance, BCL-XL, B-cell lymphoma-extra large, Gαq, Gq protein alpha subunit, GCK, glucokinase, PI3K, phosphatidylinositol 3 kinases, Systematic review, TLR-2/4, toll-like receptor 2/4, IR, insulin receptor, PERK, protein kinase RNA-like eukaryotic initiation factor 2A kinase, 030220 oncology & carcinogenesis, CRP, C-reactive protein, IRS, insulin receptor substrate, AM, mesangial area, JAK, Janus kinase, FBG, fasting blood glucose, ETAR, endothelium A receptor, LDL-C, low density lipoprotein-cholesterol, CD2AP, CD2-associated protein, eIF2α, eukaryotic initiation factor 2α, RM1-950, mTOR, mammalian target of rapamycin, CHOP, C/EBP homologous protein, STZ, streptozotocin, 03 medical and health sciences, ADE, adverse event, PKC, protein kinase C, LC3, microtubule-associated protein light chain 3, ORP150, 150-kDa oxygen-regulated protein, PGE2, prostaglandin E2, IL-1β/6, interleukin 1β/6, Diabetic kidney disease, IGF-1, insulin-like growth factor 1, EP, E-prostanoid receptor, FN, fibronectin, eGFR, estimated GFR, MDA, malondialdehyde, Chinese medicine, MMP-2, matrix metallopeptidase 2, XBP-1, spliced X box-binding protein 1, TGF-β, tumor growth factor β, GRB 10, growth factor receptor-bound protein 10, medicine.disease, Clinical trial, GRP78, glucose-regulated protein 78, UP, urinary protein, IGF-1R, insulin-like growth factor 1 receptor, ACEI, angiotensin-converting enzyme inhibitor, BCL-2, B-cell lymphoma 2, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase, MYD88, myeloid differentiation primary response 88, PBG, postprandial blood glucose, RCT, randomized clinical trial, N/R, not reported, COL-I/IV, collagen I/IV, PINK1, PTEN-induced putative kinase 1, UACR, urinary albumin to creatinine ratio, C, control group, Diabetic nephropathy, GPX, glutathione peroxidase, ICAM-1, intercellular adhesion molecule-1, Bioinformatics, VCAM-1, vascular cell adhesion molecule-1, AMPKα, adenosine monophosphate-activated protein kinase α, DM, diabetes mellitus, TFEB, transcription factor EB, TNF-α, tumor necrosis factor α, Molecular target, IKK-β, IκB kinase β, Signaling pathway, GLUT4, glucose transporter type 4, BAX, BCL-2-associated X protein, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, PARP, poly(ADP-Ribose) polymerase, SMURF-2, SMAD ubiquitination regulatory factor 2, AREs, antioxidant response elements, MD, mean difference, SMAD, small mothers against decapentaplegic, MCP-1, monocyte chemotactic protein-1, VEGF, vascular endothelial growth factor, cAMP, cyclic adenosine monophosphate, ARB, angiotensin receptor blocker, PAI-1, plasminogen activator inhibitor-1, SMD, standard mean difference, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, IκB-α, inhibitory protein α, Herbal medicine, TCM, traditional Chinese medicine, DG, glomerular diameter, GSK-3, glycogen synthase kinase 3, SIRT1, sirtuin 1, D, duration, HbA1c, glycosylated hemoglobin, WMD, weight mean difference, CTGF, connective tissue growth factor, ER, endoplasmic reticulum, DN, diabetic nephropathy, ROS, reactive oxygen species, CCR, creatinine clearance rate, SOD, superoxide dismutase, Diabetes mellitus, PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1α, ET-1, endothelin-1, UMA, urinary microalbumin, SCr, serum creatinine, IRE-1α, inositol-requiring enzyme-1α, 030304 developmental biology, TII, tubulointerstitial injury index, RAGE, receptors of AGE, business.industry, GFR, glomerular filtration rate, PTEN, phosphatase and tensin homolog, CI, confidence interval, TC, total cholesterol, SD-rat, Sprague–Dawley rat, UAER, urinary albumin excretion rate, DKD, diabetic kidney disease, T, treatment group, Molecular targets, Therapeutics. Pharmacology, α-SMA, α smooth muscle actin, SD, standard deviation, business, DAG, diacylglycerol, GCLC, glutamate-cysteine ligase catalytic subunit, Kidney disease

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    المساهمون: Jawaharlal Nehru Technological University, Hyderabad 500085, India (JNTU), Osmania University, Plate-forme ImPACcell (ImPACcell), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre de Recherche en Cancérologie Nantes-Angers (CRCNA), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Hôtel-Dieu de Nantes-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Laennec-Centre National de la Recherche Scientifique (CNRS)-Faculté de Médecine d'Angers-Centre hospitalier universitaire de Nantes (CHU Nantes), CRLCC René Gauducheau, CSIR Indian Institute of Chemical Technology (IICT), Institut des Sciences Chimiques de Rennes (ISCR), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), Bioprojet-Biotech, Financial support by the 'Ligue contre le Cancer, Conseil Interrégional Grand Ouest' is gratefully acknowledged., Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Bioorganic & Medicinal Chemistry Letters
    Bioorganic & Medicinal Chemistry Letters, 2021, 52, pp.128390. ⟨10.1016/j.bmcl.2021.128390⟩

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    المصدر: JHEP Reports, Vol 3, Iss 3, Pp 100250-(2021)
    JHEP Reports

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    المساهمون: Universidad de Cantabria

    المصدر: JHEP Reports, Vol 3, Iss 3, Pp 100276-(2021)
    JHEP Reports Volume 3, Issue 3, June 2021, 100276
    UCrea Repositorio Abierto de la Universidad de Cantabria
    Universidad de Cantabria (UC)
    JHEP Reports

    مصطلحات موضوعية: Mitochondrial ROS, MMP, mitochondrial membrane potential, LSM, liver stiffness, MPO, myeloperoxidase, AST, aspartate aminotransferase, Pgc1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha, RC799-869, Pharmacology, p-JNK, phosphor-JNK, TNF, tumour necrosis factor, Tfam, transcription factor A mitochondrial, Ccr5, C-C motif chemokine receptor 5, Immunology and Allergy, CLD, cholestatic liver disease, MLKL, mixed-lineage kinase domain-like pseudokinase, shRNA, small hairpin RNA, ANA, antinuclear antibodies, Hif-1α, hypoxia-inducible factor 1-alpha, Liver injury, GCDCA, glycochenodeoxycholic acid, Cholestasis, Bile acid, MCJ, methylation-controlled J, SDH2, succinate dehydrogenase, Gastroenterology, α-SMA, alpha-smooth muscle actin, Pgc1β, peroxisome proliferator-activated receptor gamma coactivator 1-beta, ROS, Bile duct ligation, Diseases of the digestive system. Gastroenterology, Mitochondria, Ccr2, C-C motif chemokine receptor 2, Ezh2, enhancer of zeste homolog 2, Mitochondrial respiratory chain, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, JNK, c-Jun N-terminal kinase, BA, bile acid, BAX, BCL2 associated X, RT, room temperature, VCTE, vibration-controlled transient elastography, HSC, hepatic stellate cells, Research Article, PARP, poly (ADP-ribose) polymerase, Cxcl1, C-X-C motif chemokine ligand 1, p-MLKL, phosphor-MLKL, medicine.drug_class, mRNA, messenger ribonucleic acid, ETC, electron transport chain, Nrf1, nuclear respiratory factor 1, APRI, AST to platelet ratio index, BDL, bile duct ligation, Ccl2, C-C motif chemokine ligand 2, MPT, mitochondrial permeability transition, UDCA, ursodeoxycholic acid, Primary sclerosing cholangitis, AMA-M2, antimitochondrial M2 antibody, ROS, reactive oxygen species, BCL-Xl, B-cell lymphoma-extra large, ALT, alanine aminotransferase, Internal Medicine, medicine, Trail, TNF-related apoptosis-inducing ligand, tBIL, total bilirubin, KO, knockout, ALP, alkaline phosphatase, Hepatology, business.industry, medicine.disease, WT, wild-type, MCJ, PSC, primary sclerosing cholangitis, DCA, deoxycholic acid, Mitochondrial permeability transition pore, siRNA, small interfering RNA, Ucp2, uncoupling protein 2, Fxr, farnesoid X receptor, Hepatic stellate cell, PBC, primary biliary cholangitis, business, Cyp7α1, cholesterol 7 alpha-hydroxylase, BCL-2, B-cell lymphoma 2, MAPK, mitogen-activated protein kinase, Abs, antibodies

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    المصدر: JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 187-199 (2018)
    JACC: Basic to Translational Science

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