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المؤلفون: Ying Han, Xintong Zhang, Wei Huang, Zhonggao Gao, Mingji Jin
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1789-1812 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: SLC, solute carrier, Bioavailability, AMI, amiodarone, MPA, mycophenolic acid, TLCA, taurolithocholate, ASP, amisulpride, RA, rheumatoid arthritis, Review, NRs, nitroreductases, MDR1, multidrug resistance gene 1, NaGC, sodium glycholate, MATEs, multidrug and toxin extrusion proteins, NMEs, new molecular entities, 0302 clinical medicine, HFD, high fat diet, P-gp, P-glycoprotein, ACS, amphipathic chitosan derivative, Medicine, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, 0303 health sciences, Gastrointestinal tract, IBD, inflammatory bowel disease, pKa, dissociation constant, RBC, red blood cell, FA, folate, OATs, organic anion transporters, 030220 oncology & carcinogenesis, MKC, monoketocholic acid, the GI tract, the gastrointestinal tract, AQP4, aquaporin 4, OCTNs, organic zwitterion/cation, T2D, type 2 diabetes, Gut microbiota, RM1-950, WHO, World Health Organization, 03 medical and health sciences, EcN, Escherichia coli Nissle 1917, Drug Transport Process, BDEPT, the bacteria-directed enzyme prodrug therapy, BCS, biopharmaceutics classification system, NEC, necrotizing enterocolitis, DRPs, digoxin reduction products, NaDC, sodium deoxycholate, Probiotics, CPP, cell-penetrating peptide, OCTs, organic cation transporters, TDCA, taurodeoxycholate, cgr operon, cardiac glycoside reductase operon, RA - Rheumatoid arthritis, DCA, deoxycholic acid, AA, ascorbic acid, BBR, berberine, Personalized medicine, BDDCS, the biopharmaceutics drug disposition classification system, SSZ, sulfasalazine, UDC, ursodeoxycholic acid, PPIs, proton pump inhibitors, BCRP, breast cancer resistance protein, CS, chitosan, Gut flora, Bioinformatics, PD, Parkinson's disease, SLN, solid lipid nanoparticle, SGLT-1, sodium-coupled glucose transporter 1, Oral administration, MRP2, multidrug resistance-associated protein 2, FAO, Food and Agriculture Organization of the United Nations, SVCT-1/2, the sodium-dependent vitamin C transporter-1/2, an OTC drug, an over-the-counter drug, CA, cholic acid, biology, ABC, ATP-binding cassette, T1DM, type 1 diabetes mellitus, NSAIDs, non-steroidal anti-inflammatory drugs, AR, azoreductase, GCDC, glycochenodeoxycholate, Drug delivery, GL, glycyrrhizic acid, PT, pectin, LPS, lipopolysaccharide, TME, the tumor microenvironment, T1D, type 1 diabetes, TCDC, taurochenodeoxycholate, Oral drugs, MDR1a, multidrug resistance protein-1a, SCFAs, short-chain fatty acids, CDCA, chenodeoxycholic acid, 030304 developmental biology, business.industry, dhBBR, dihydroberberine, biology.organism_classification, HTC, hematocrit, PWSDs, poorly water-soluble drugs, Colon-specific drug delivery system, stomatognathic diseases, SP, sulfapyridine, 5-ASA, 5-aminosalicylic acid, BSH, bile salt hydrolase, TCA, taurocholate, Therapeutics. Pharmacology, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d001e27a816f9de7d75ff16dd2143ecTest
http://www.sciencedirect.com/science/article/pii/S2211383520307279Test -
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المؤلفون: Ranchen Xu, Xin Liu, Rui Geng, Yong Zhang, Shuqian Zhang, Yunwei Wei, Xue Bai, Hui Chen, Xia Li, Yang Liu, Heng Liu, Tong Zhao, Lei Wang, Mingqi Li, Huimin Li, Hao Cui, Baofeng Yang
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 812-824 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: MMP-8, matrix metallopeptidase 8, Original article, Berberine, medicine.medical_treatment, Intraperitoneal injection, SPR, surface plasmon resonance, Matrix metalloproteinase, Peritoneal adhesions, Peritoneal adhesion, ICAM-1, intercellular cell adhesion molecule-1, 03 medical and health sciences, Cecum, chemistry.chemical_compound, 0302 clinical medicine, TIMP-1, H&E, hemotoxylin and eosin, TIMP-1, tissue inhibitor of metalloproteinases 1, Vegfα, vascular endothelial growth factor α, MMP-3, matrix metallopeptidase 3, medicine, In patient, EDC, 1-ethyl-3-(3-dimethylpropyl)-carbodiimide, General Pharmacology, Toxicology and Pharmaceutics, NMR, nuclear magnetic resonance, PEG, polyethylene glycol, 030304 developmental biology, 0303 health sciences, lcsh:RM1-950, ABSO, adhesive small bowel obstruction, HPX, hemopexin-like, Adhesion, NHS, N-hydroxysuccinimide, ECM, extracellular matrix, medicine.anatomical_structure, lcsh:Therapeutics. Pharmacology, chemistry, 030220 oncology & carcinogenesis, Cancer research, BBR, berberine, Adhesion reformation, FSP-1, fibroblasts specific protein 1, LSPR, localized surface plasmon resonance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d7100468582649dad77af3c406e89fTest
http://www.sciencedirect.com/science/article/pii/S221138351930841XTest -
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المؤلفون: Jiang Wang, Hualiang Jiang, Hong Liu, Chenglin Wu, Zhao Jing, Wang Yiping, Junhua Tong, Xi Cong
المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1216-1230 (2019)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: Tetrahydroprotoberberine derivatives, HFD, high-fat diet, POCl3, phosphoryl trichloride, Pharmacology, CHD, coronary heart disease, DiI-LDL, low-density lipoprotein, labeled with 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl-indocarbocyanine perchlorate, PCSK9, t1/2, half-life, chemistry.chemical_compound, 0302 clinical medicine, Berberine, Hyperlipidemia, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, hERG, human ether-à-go-go related gene, LDLR, low-density lipoprotein receptor, 030220 oncology & carcinogenesis, Low-density lipoprotein, AUC, area under the plasma concentration−time curve, Kexin, lipids (amino acids, peptides, and proteins), MRT, mean residence time, CVDs, cardiovascular diseases, mAbs, monoclonal antibodies, Original article, PK, pharmacokinetic, 03 medical and health sciences, medicine, Cmax, maximum concentration, Low-density lipoprotein cholesterol, LDL-C, low-density lipoprotein-cholesterol, Low-density lipoprotein receptor, Total cholesterol, THPBs, tetrahydroprotoberberine derivatives, ADH, autosomal dominant hypercholesterolemia, 030304 developmental biology, Lipid-lowering, Hyperlipidemia hamster, lcsh:RM1-950, Proprotein convertase, medicine.disease, PCSK9 expression, TC, total cholesterol, lcsh:Therapeutics. Pharmacology, FDA, food and drug administration, chemistry, LDL receptor, BBR, berberine, PCSK9, proprotein convertase subtilisin/kexin type 9, CL, clearance, F, oral bioavailability, Lipoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320ead47ecd96b8853bf0cb6e07e3c6fTest
https://doi.org/10.1016/j.apsb.2019.06.006Test -
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المؤلفون: Qing, Zhang, Jia, Liu, Huxinyue, Duan, Ruolan, Li, Wei, Peng, Chunjie, Wu
المصدر: Journal of Advanced Research
مصطلحات موضوعية: SMT, Samul-Tang Tang, ICAM, intercellular adhesion molecule, TrxR1, thioredoxin reductase-1, HG, high glucose, SchB, Schisandrin B, Z-Lig, Z-ligustilide, CINM, Cinnamaldehyde, PA, Palmitate, ET, endothelin, OA, Oleanolic acid, ApoE, apolipoprotein E, LWDH, Liuwei-Dihuang pill, PEITC, phenethyl isocyanate, DMY, Dihydromyricetin, 7-HMR, (−)-7(S)-hydroxymatairesinol, APV, aqueous extracts of Prunella Vulgaris, KGRE, extracts of KGR, AGE, advanced glycation end product, MA, maslinic acid, NAF, Nepeta Angustifolia, OMT, Oxymatrine, MCP-1, monocyte chemotactic protein 1, PT, Pterostilbene, HXC, Huoxue capsule, CVDs, cardiovascular diseases, Vascular endothelial cells, ECs, endothelial cells, NF-E2-Related Factor 2, CNC, Cap'n'collar, VA, Vanillic acid, Article, BITC, benzyl isothiocyanate, Molecular mechanism, FFA, Fatty Acids, ASD-IV, Astragaloside IV, KRG, Korean red ginseng, OX-LDL, oxidized low density lipoprotein, VEC, vascular endothelial cells, PI3K, phosphatidylinositol 3 kinase, PKC, protein kinase C, Humans, MCGA3, 3-O-caffeoyl-1-methylquinic acid, EXS, Xanthoceras sorbifolia, HIF-1, Hypoxia-inducible factor 1, SAL, Salidroside, ERK, extracellular regulated protein kinases, IL, interleukin, Oxidative stress, Akt, protein kinase B, Nrf2/HO-1 signaling, TXA2, Thromboxane A2, MMPs, matrix metalloproteinases, RBPC, phenolic extracts derived from rice bran, NG, naringenin, Heme Oxygenase-1, VEI, vascular endothelial injury, ADH, andrographolide, ARE, antioxidant reaction elements, US, uraemic serum, XAG, xanthoangelol, Keap1, kelch-like epichlorohydrin-related proteins, MAPKs, mitogen-activated protein kinases, Hcy, Homocysteine, NQO1, NAD(P)H: quinone oxidoreductase, SFN, sulforaphane, ASP, Angelica sinensis polysaccharide, TNF, tumor necrosis factor, PAA, Pachymic acid, eNOS, endothelial NO synthase, ASTP, Astragalus polysacharin, MAPKK, mitogen-activated protein kinase kinase, Pharmaceutical Preparations, HO-1, heme oxygenase, GPx, Glutathione peroxidase, CVRF, cardiovascular risk factors, EGCG, epigallocatechin-3-O-gallate, Herbal medicine, TCM, traditional Chinese medicine, AS, atherosclerosis, Gau A, Glaucocalyxin A, XXT, Xueshuan Xinmaining Tablet, HAMS, human anthocyanin medicated serum, GTE, Ganoderma tsugae extracts, HUVECs, human umbilical vein endothelial cells, CREB, cAMP-response element binding protein, BBR, Berberine, ROS, reactive oxygen species, SOD, superoxide dismutase, Nrf2, nuclear factor erythroid-2 related factor 2, ComputingMethodologies_COMPUTERGRAPHICS, C3G, Cyanidin-3-O-glucoside, Sal B, salvianolic acid B, Endothelial Cells, Atherosclerosis, BAECs, bovine artery endothelial cells, NF-κB, nuclear factor kappa-B, AMP, Athyrium Multidentatum, GSD Rg1, Ginsenoside Rg1, ECC, (−)-Epicatechin, PAI-1, plasminogen activator Inhibitor-1, Ang, Angiotensin, VCAM, vascular cell adhesion molecule
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::9de6be7acea23fd93887832ef07452a1Test
https://pubmed.ncbi.nlm.nih.gov/35024180Test -
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المؤلفون: Yang, Liu, Xiaojia, Liu, Na, Zhang, Mingxiao, Yin, Jingwen, Dong, Qingxuan, Zeng, Genxiang, Mao, Danqing, Song, Lu, Liu, Hongbin, Deng
المصدر: Acta Pharmaceutica Sinica. B
مصطلحات موضوعية: PD-L1, Berberine, MDSCs, myeloid-derived suppressor cells, CQ, chloroquine, SPR, surface plasmon resonance, TNF-α, tumor necrosis factor-α, T-cell immunity, CHX, cycloheximide, NSCLC, non-small cell lung cancer, Tregs, regulatory T-lymphocytes, COP9 signalosome 5, ICB, immune checkpoint blockade, AMC, 7-amino-4-methylcoumarin, IB, immunoblotting, Ub, ubiquitin, IFN-γ, interferon-gamma, PD-1/PD-L1 axis, qRT-PCR, quantitative real-time polymerase chain reaction, PD-1, programmed cell death-1, PD-L1, programmed cell death ligand-1, NFAT, nuclear factor of activated T-cells, Baf, bafilomycin, TILs, tumor-infiltrating lymphocytes, Original Article, BBR, berberine, CSN5, COP9 signalosome 5, TCM, traditional Chinese medicine, Immune checkpoint blockade, IHC, immunohistochemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::406d19472a869bf112c9ffacba5b29bcTest
https://pubmed.ncbi.nlm.nih.gov/33354502Test -
6دورية أكاديمية
المؤلفون: Zhang,Haitao
المساهمون: TULANE UNIV NEW ORLEANS LA NEW ORLEANS United States
مصطلحات موضوعية: Prostate cancer, androgens, resistance, therapeutics, inhibition, ar(Androgen receptor), bbr(Berberine), natural compounds, castration resistant, AR splice variants, steroidogenesis, AR protein, AKT, mRNA, splice variants, therapeutic concepts, cancer cells, isoquinoline alkaloids, gene transcription
وصف الملف: text/html
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7دورية أكاديمية
المؤلفون: Zhang,Haitao
المساهمون: Tulane University New Orleans United States
مصطلحات موضوعية: MEDICAL RESEARCH, prostate cancer, ANDROGEN RECEPTORs, BBR(BERBERINE), CRPC(CASTRATION RESISTANT PROSTATE CANCER), SPLICE VARIANTS, taxane chemotherapy, microtubules, dimerization, natural compounds, LuCaP86.2
وصف الملف: text/html
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المؤلفون: Jian-Bo Wan, Xuejing Jia, Chuwen Li, Peng Li, Shenghui Chen, Kai Wang, Xiaotong Wang, Kechun Liu, Jiaolin Bao, Huanxing Su, Yeer Liang, Chao Zhang, Zhiping Li, Simon Ming-Yuen Lee, Chengwei He, Meiwan Chen
المصدر: Redox Biology, Vol 11, Iss, Pp 1-11 (2017)
Redox Biologyمصطلحات موضوعية: 0301 basic medicine, MTT, thiazolyl blue tetrazolium bromide, Berberine, Clinical Biochemistry, Apoptosis, TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling, Pharmacology, DMSO, dimethyl sulfoxide, medicine.disease_cause, Biochemistry, PD, Parkinson's disease, Antioxidants, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, HD, Huntington's disease, lcsh:QH301-705.5, Zebrafish, HO-1, heme oxygenase-1, lcsh:R5-920, 6-OHDA, 6-hydroxydopamine, Chemistry, DA, dopaminergic, FCM, flow cytometry, Neuroprotection, Oncogene Protein v-akt, Neuroprotective Agents, Proto-Oncogene Proteins c-bcl-2, HS, horse serum, dpf, day post fertilization, JNK, c-Jun N-terminal kinase, AD, Alzheimer's disease, FITC, fluorescein isothiocyanate, lcsh:Medicine (General), PI3K, phosphoinositide 3-kinase, Signal Transduction, Research Paper, Nom, nomifensine, Cell Survival, NF-E2-Related Factor 2, TH, tyrosine hydroxylase, ZnPP, zinc protoporphyrin IX, AKT, protein kinase B, PI, propidium iodide, 03 medical and health sciences, Hormesis, PBS, phosphate buffered saline, FBS, fetal bovine serum, medicine, Animals, Humans, Viability assay, Parkinson Disease, Secondary, Oxidopamine, Protein kinase B, PI3K/AKT/mTOR pathway, PS, penicillin-streptomycin, Dopaminergic Neurons, Organic Chemistry, NDD, neurodegenerative disorders, Neurotoxicity, PC12 cells, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, lcsh:Biology (General), MAPK, mitogen-activated protein kinases, sMaf, small Maf, BBR, berberine, Reactive Oxygen Species, Nrf2, nuclear factor-E2-related factor 2, 030217 neurology & neurosurgery, Oxidative stress, Heme Oxygenase-1
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86874b4a4ccaf6d0a6a5994e64939db1Test