المؤلفون: Silvoniemi, Antti, Laine, Jukka, Aro, Katri, Nissi, Linda, Bäck, Leif, Schildt, Jukka, Hirvonen, Jussi, Hagström, Jaana, Irjala, Heikki, Aaltonen, Leena-Maija, Seppänen, Marko

المساهمون: HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka, Clinicum, Helsinki University Hospital Area, HUS Medical Imaging Center, Department of Diagnostics and Therapeutics, HUS Diagnostic Center, HUSLAB, Medicum, Department of Pathology

مصطلحات موضوعية: Ct, Fdg-pet, cfDNA, circulating tumor DNA, ctDNA, Head and neck cancer, Liquid biopsy, Metabolic tumor volume, Next-generation sequencing, Total lesion glycolysis, Variant allele frequency, 3122 Cancers

وصف الملف: application/pdf

العلاقة: Silvoniemi , A , Laine , J , Aro , K , Nissi , L , Bäck , L , Schildt , J , Hirvonen , J , Hagström , J , Irjala , H , Aaltonen , L-M & Seppänen , M 2023 , ' Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma : Association with Metabolic Tumor Burden Determined with FDG-PET/CT ' , Cancers , vol. 15 , no. 15 , 3970 . https://doi.org/10.3390/cancers15153970Test; ORCID: /0000-0001-6079-7881/work/142004654; 7219d514-da16-4393-9462-c2a76f8fa092; http://hdl.handle.net/10138/572868Test; 001045452700001

الإتاحة: http://hdl.handle.net/10138/572868Test

المؤلفون: Silvoniemi, Antti, Laine, Jukka, Aro, Katri, Nissi, Linda, Bäck, Leif, Schildt, Jukka, Hirvonen, Jussi, Hagström, Jaana, Irjala, Heikki, Aaltonen, Leena Maija, Seppänen, Marko, Minn, Heikki

المساهمون: Tampere University, Clinical Medicine, Imaging

مصطلحات موضوعية: 3126 Surgery, anesthesiology, intensive care, radiology, 3122 Cancers

وصف الملف: fulltext

العلاقة: 3970; 15; ORCID: /0000-0002-0368-3746/work/145455878; https://trepo.tuni.fi/handle/10024/150988Test; URN:NBN:fi:tuni-202309057969

الإتاحة: https://doi.org/10.3390/cancers15153970Test
https://trepo.tuni.fi/handle/10024/150988Test

المؤلفون: Bachour, Adel, Bäck, Leif, Pietarinen, Petra

المساهمون: HUS Heart and Lung Center, Clinicum, Helsinki University Hospital Area, HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka

مصطلحات موضوعية: CPAP failure, CPAP pressure, oral appliance, pacemaker, sleep apnoea, upper airway stimulation, UPPER-AIRWAY STIMULATION, TERM COST-EFFECTIVENESS, NERVE-STIMULATION, PATIENT SELECTION, ENDOSCOPY, PRESSURE, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: Helsingin ja Uudenmaan Sairaanhoitopiiri, Grant/Award Number: Y code 2019SK003 and VY1169006; Bachour , A , Bäck , L & Pietarinen , P 2021 , ' No changes in nocturnal respiration with hypoglossal neurostimulation therapy for obstructive sleep apnoea ' , The Clinical Respiratory Journal , vol. 15 , no. 3 , pp. 329-335 . https://doi.org/10.1111/crj.13303Test; ORCID: /0000-0002-7367-6613/work/127008272; 36cbf7b4-5f53-4ff9-a881-a06c19fca5ee; http://hdl.handle.net/10138/353232Test; 000594409800001

الإتاحة: http://hdl.handle.net/10138/353232Test

المؤلفون: Rehell, Minna, Atula, Timo, Tapiovaara, Laura K., Bäck, Leif J. J., Koskinen, Anni I. M., Ruohoalho, Johanna, Aro, Katri L. S.

المساهمون: Korva-, nenä- ja kurkkutautien klinikka, HUS Head and Neck Center, Clinicum, Faculty Common Matters (Faculty of Medicine)

مصطلحات موضوعية: Lymphadenopathy, open neck biopsy, fine needle aspiration cytology, core needle biopsy, CORE-NEEDLE-BIOPSY, CLASSIFICATION, CANCER, MASS, 3125 Otorhinolaryngology, ophthalmology

وصف الملف: application/pdf

العلاقة: This work was supported by the Helsinki University Hospital Research Fund.; Rehell , M , Atula , T , Tapiovaara , L K , Bäck , L J J , Koskinen , A I M , Ruohoalho , J & Aro , K L S 2022 , ' Complications in lymph node excision in the head and neck area ' , Acta Oto-Laryngologica , vol. 142 , pp. 738-742 . https://doi.org/10.1080/00016489.2022.2115551Test; ORCID: /0000-0002-6560-1128/work/127504048; 875dc986-c99c-4191-b8d9-90b2a0570f60; http://hdl.handle.net/10138/353571Test; 000854139200001

الإتاحة: http://hdl.handle.net/10138/353571Test

المؤلفون: Mäkitie, Antti, Kamali, Alexander, Mroueh, Rayan, Lindford, Andrew, Koivunen, Petri, Autio, Timo, Lassus, Patrik, Halle, Martin, Bäck, Leif, Palmgren, Björn, Hammarstedt-Nordenvall, Lalle

المساهمون: HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka, Research Program in Systems Oncology, Faculty of Medicine, Clinicum, HUS Musculoskeletal and Plastic Surgery, Plastiikkakirurgian yksikkö

مصطلحات موضوعية: Tongue cancer, reconstruction, outcome, recurrence, SQUAMOUS-CELL CARCINOMA, QUALITY-OF-LIFE, LYMPH-NODES, DETERMINANTS, RESECTION, SURVIVAL, BIOPSY, HEAD, 3125 Otorhinolaryngology, ophthalmology

وصف الملف: application/pdf

العلاقة: Financial support provided by The Laryngeal Foundation, Karolinska Institutet and the Stiftelsen Acta Oto-Laryngologica Foundation in Sweden and the Helsinki University Hospital Research Fund and the Finska Lakaresallskapet in Finland.; Mäkitie , A , Kamali , A , Mroueh , R , Lindford , A , Koivunen , P , Autio , T , Lassus , P , Halle , M , Bäck , L , Palmgren , B & Hammarstedt-Nordenvall , L 2020 , ' A descriptive study highlighting the differences in the treatment protocol for oral tongue cancer in Sweden and Finland ' , Acta Oto-Laryngologica , vol. 140 , no. 2 , pp. 188-194 . https://doi.org/10.1080/00016489.2019.1699663Test; 55c8731d-44ce-4f35-97f0-83c2f9eb8ef2; http://hdl.handle.net/10138/563407Test; 000503623200001

الإتاحة: http://hdl.handle.net/10138/563407Test

المؤلفون: Nieminen, Teija, Tapiovaara, Laura, Bäck, Leif, Lindford, Andrew, Lassus, Patrik, Lehtonen, Lasse, Mäkitie, Antti, Keski-Säntti, Harri

المساهمون: Helsingin ja Uudenmaan Sairaanhoitopiiri, University of Helsinki

المصدر: European Archives of Oto-Rhino-Laryngology ; volume 281, issue 2, page 907-914 ; ISSN 0937-4477 1434-4726

مصطلحات موضوعية: General Medicine, Otorhinolaryngology

الإتاحة: https://doi.org/10.1007/s00405-023-08292-3Test

المؤلفون: Nieminen, Teija, Tapiovaara, Laura, Bäck, Leif, Lindford, Andrew, Lassus, Patrik, Lehtonen, Lasse, Mäkitie, Antti, Keski-Säntti, Harri

المصدر: European Archives of Oto-Rhino-Laryngology; Feb2024, Vol. 281 Issue 2, p907-914, 8p

مصطلحات موضوعية: FREE flaps, ENHANCED recovery after surgery protocol, HEAD & neck cancer, SURGICAL complications, POSTOPERATIVE care, INTENSIVE care units

المؤلفون: Clubb, James H. A., Kudling, Tatiana V., Heinioe, Camilla, Basnet, Saru, Pakola, Santeri, Cervera Carrascon, Victor, Santos, Joao Manuel, Quixabeira, Dafne C. A., Havunen, Riikka, Sorsa, Suvi, Zheng, Vincent, Salo, Tuula, Bäck, Leif, Aro, Katri, Tulokas, Sanni, Loimu, Venla, Hemminki, Akseli

المساهمون: Medicum, TRIMM - Translational Immunology Research Program, Research Programs Unit, Faculty of Medicine, HUS Comprehensive Cancer Center, HUSLAB, Department of Oral and Maxillofacial Diseases, Clinicum, Department of Oncology, HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka

مصطلحات موضوعية: adenovirus, immune checkpoint inhibitor, head and neck cancer, immunotherapy, tertiary lymphoid neogenesis, TNFa, IL2, oncolytic virotherapy, SQUAMOUS-CELL CARCINOMA, INTRAEPITHELIAL NEOPLASIA GRADE-2, TNF-ALPHA, THERAPY, RECURRENT, RESISTANCE, SURVIVAL, RISK, 3111 Biomedicine, 3122 Cancers

وصف الملف: application/pdf

العلاقة: This study received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 813453. This study was supported by Jane and Aatos Erkko Foundation, HUCH Research Funds (VTR), Finnish Cancer Organizations, University of Helsinki, Novo Nordisk Foundation, Paivikki and Sakari Sohlberg Foundation, TILT Biotherapeutics Ltd. We thank Albert Ehrnrooth and Karl Fazer for research support. The funders were not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication.; Clubb , J H A , Kudling , T V , Heinioe , C , Basnet , S , Pakola , S , Cervera Carrascon , V , Santos , J M , Quixabeira , D C A , Havunen , R , Sorsa , S , Zheng , V , Salo , T , Bäck , L , Aro , K , Tulokas , S , Loimu , V & Hemminki , A 2022 , ' Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer ' , Frontiers in Immunology , vol. 13 , 794251 . https://doi.org/10.3389/fimmu.2022.794251Test; ORCID: /0000-0001-6039-0088/work/112288101; ORCID: /0000-0001-6235-8612/work/113990064; ORCID: /0009-0009-8379-1584/work/134969188; ORCID: /0000-0001-7103-8530/work/156151436; http://hdl.handle.net/10138/352146Test; 656f4466-22fe-4ab0-9bc5-dae704b6e895; 000773608000001

الإتاحة: http://hdl.handle.net/10138/352146Test

المؤلفون: Kudling, Tatiana V., Clubb, James H. A., Quixabeira, Dafne C. A., Santos, Joao M., Havunen, Riikka, Kononov, Alexander, Heiniö, Camilla, Cervera-Carrascon, Victor, Pakola, Santeri, Basnet, Saru, Grönberg-Vähä-Koskela, Susanna, Arias, Victor, Gladwyn-Ng, Ivan, Aro, Katri, Bäck, Leif, Räsänen, Jari, Ilonen, Ilkka, Borenius, Kristian, Räsänen, Mikko, Hemminki, Otto, Rannikko, Antti, Kanerva, Anna, Tapper, Johanna, Hemminki, Akseli

المساهمون: TRIMM - Translational Immunology Research Program, Research Programs Unit, HUS Comprehensive Cancer Center, Department of Oncology, HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka, Clinicum, HUS Heart and Lung Center, III kirurgian klinikka, Department of Surgery, HUS Abdominal Center, Urologian yksikkö, HUS Gynecology and Obstetrics, Akseli Eetu Hemminki / Principal Investigator, Department of Obstetrics and Gynecology

مصطلحات موضوعية: Oncolytic virus, adenovirus, interleukin 7, immunotherapy, RESECTED CUTANEOUS MELANOMA, T-CELLS, IL-7, EXPANSION, CD8(+), EXPRESSION, MODEL, 3122 Cancers

وصف الملف: application/pdf

العلاقة: This study was supported by Doctoral programme in clinical research (University of Helsinki), Jane and Aatos Erkko Foundation, HUCH Research Funds (VTR), Finnish Cancer Organizations, Novo Nordisk Foundation, Paivikki and Sakari Sohlberg Foundation and TILT Biotherapeutics Ltd;Marie Sklodowska-Curie;Doctoral programme in clinical research, University of Helsinki, Finland;Suomen Kulttuurirahasto;TILT Biotherapeutics Ltd.; Kudling , T V , Clubb , J H A , Quixabeira , D C A , Santos , J M , Havunen , R , Kononov , A , Heiniö , C , Cervera-Carrascon , V , Pakola , S , Basnet , S , Grönberg-Vähä-Koskela , S , Arias , V , Gladwyn-Ng , I , Aro , K , Bäck , L , Räsänen , J , Ilonen , I , Borenius , K , Räsänen , M , Hemminki , O , Rannikko , A , Kanerva , A , Tapper , J & Hemminki , A 2022 , ' Local delivery of interleukin 7 with an oncolytic adenovirus activates tumor-infiltrating lymphocytes and causes tumor regression ' , OncoImmunology , vol. 11 , no. 1 , 2096572 . https://doi.org/10.1080/2162402X.2022.2096572Test; ORCID: /0000-0002-4261-3484/work/116551277; ORCID: /0000-0001-6235-8612/work/116554733; ORCID: /0000-0002-8149-3550/work/116555101; ORCID: /0000-0001-7103-8530/work/156151505; http://hdl.handle.net/10138/346497Test; 4ed7cb2f-6254-4f8e-8271-6cfe623ce91f; 000823264800001

الإتاحة: http://hdl.handle.net/10138/346497Test

المؤلفون: Abolfotouh, Sherif, Bäck, Leif, Aro, Katri, Lassus, Patrik, Vuola, Jyrki, Mesimäki, Karri, Wilkman, Tommy, Vikatmaa, Pirkka

المساهمون: HUS Musculoskeletal and Plastic Surgery, Plastiikkakirurgian yksikkö, HUS Head and Neck Center, Clinicum, Korva-, nenä- ja kurkkutautien klinikka, Suu- ja leukakirurgian yksikkö, Department of Oral and Maxillofacial Diseases, HUS Abdominal Center, Verisuonikirurgian yksikkö

مصطلحات موضوعية: Carotid interposition graft, carotid artery reconstruction, head and neck cancer, surgery, ARTERY RESECTION, MANAGEMENT, REPLACEMENT, SACRIFICE, CANCER, COMMON, GRAFT, 3125 Otorhinolaryngology, ophthalmology, 3126 Surgery, anesthesiology, intensive care, radiology

وصف الملف: application/pdf

العلاقة: Abolfotouh , S , Bäck , L , Aro , K , Lassus , P , Vuola , J , Mesimäki , K , Wilkman , T & Vikatmaa , P 2022 , ' Carotid interposition in patients with head and neck tumors : clinical experience of 13 cases reconstructed with a great saphenous vein autograft ' , Acta Oto-Laryngologica , vol. 142 , no. 5 , pp. 419-424 . https://doi.org/10.1080/00016489.2022.2067356Test; 4ab8d02c-827e-4efa-b70f-bd14b4781a37; http://hdl.handle.net/10138/346072Test; 000789739400001

الإتاحة: http://hdl.handle.net/10138/346072Test