A clinical overview of paediatric sarcoidosis: multicenter experience from Turkey
| العنوان: | A clinical overview of paediatric sarcoidosis: multicenter experience from Turkey |
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| المؤلفون: | Vafa Guliyeva, Fatma Gul Demirkan, Ramazan Emre Yiğit, Esra Esen, Yagmur Bayındır, Ruya Torun, Gulsah Kılbas, Deniz Gezgin Yıldırım, Gulcin Otar Yener, Mustafa Cakan, Ferhat Demir, Kübra Özturk, Esra Baglan, Selcuk Yuksel, Sevcan A Bakkaloglu, Balahan Bora Makay, Ayşenur Pac Kısaaslan, Merih Oray, Yelda Bilginer, Rukiye Eker Ömeroğlu, Seza Ozen, Betul Sozeri, Nuray Aktay Ayaz |
| المصدر: | Modern Rheumatology. |
| بيانات النشر: | Oxford University Press (OUP), 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Rheumatology |
| الوصف: | Objectives We aimed to outline the demographic data, clinical spectrum, treatment approach of sarcoidosis in a large group of patients and sought to figure out the variations of early-onset (EOS) and late-onset pediatric sarcoidosis (LOS). Methods The study followed a retrospective-descriptive design, with the analysis of medical records of cases diagnosed as pediatric sarcoidosis. Results Fifty-two patients were included in the study. The median age at disease onset and follow-up duration were 83 (28.2-119) and 24 (6-48) months, respectively. Ten (19.2%) cases had EOS (before 5th birthday) and 42 (80.7%) patients had LOS. The most common clinical findings at the time of the disease onset were ocular symptoms (40.4%) followed by joint manifestation (25%), dermatologic symptoms (13.5%), and features related to multi-organ involvement (11.5%). Anterior uveitis was the most common (55%) one among ocular manifestations. Patients with EOS displayed joint, eye, and dermatological findings more commonly than patients with LOS. The recurrence rate of disease in patients with EOS (5.7%) and LOS (21.1%) were not statistically different (p=0.7). Conclusions Patients with EOS and LOS may present with variable clinical features and studies addressing pediatric sarcoidosis cases in collaboration between disciplines will enhance the awareness of this rare disease among physicians and assist early diagnosis with lesser complications. |
| تدمد: | 1439-7609 1439-7595 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::64d5d403ea6188d2d4ea7f83c4c92142Test https://doi.org/10.1093/mr/road050Test |
| حقوق: | EMBARGO |
| رقم الانضمام: | edsair.doi...........64d5d403ea6188d2d4ea7f83c4c92142 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14397609 14397595 |
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