المؤلفون: Johanna I. Kiiski, Mikko Neuvonen, Mika Kurkela, Päivi Hirvensalo, Kreetta Hämäläinen, E. Katriina Tarkiainen, Johanna Sistonen, Mari Korhonen, Sofia Khan, Arto Orpana, Anne M. Filppula, Marko Lehtonen, Mikko Niemi

المصدر: Human Genomics, Vol 18, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: CYP2D6, Solanidine, Drug metabolism, Biomarkers, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1479-7364Test

الوصول الحر: https://doaj.org/article/18cc2cbe5e4e47a0accb684473def9e1Test

المؤلفون: Tien Viet Tran, Kien Xuan Dang, Quynh Huong Pham, Ung Dinh Nguyen, Nhung Thi Trang Trinh, Luong Van Hoang, Son Anh Ho, Ba Van Nguyen, Duc Trong Nguyen, Dung Tuan Trinh, Dung Ngoc Tran, Arto Orpana, Ulf-Håkan Stenman, Jakob Stenman, Tho Huu Ho

المصدر: BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: Thyroid cancer, BRAF mutation, mRNA mutation assay, Diagnosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s12885-020-06862-wTest; https://doaj.org/toc/1471-2407Test

الوصول الحر: https://doaj.org/article/ba2c1835887f4f8daf13b2c8c340b522Test

المؤلفون: Johanna I. Kiiski, Mikko Neuvonen, Mika Kurkela, Päivi Hirvensalo, Kreetta Hämäläinen, E. Katriina Tarkiainen, Johanna Sistonen, Mari Korhonen, Sofia Khan, Arto Orpana, Anne M. Filppula, Marko Lehtonen, Mikko Niemi

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Physiology, Pharmacology, Cancer, Mental Health, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, CYP2D6, Solanidine, Drug metabolism, Biomarkers

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Solanidine_is_a_sensitive_and_specific_dietary_biomarker_for_CYP2D6_activity/25132101Test

الإتاحة: https://doi.org/10.6084/m9.figshare.25132101.v1Test
https://figshare.com/articles/journal_contribution/Additional_file_1_of_Solanidine_is_a_sensitive_and_specific_dietary_biomarker_for_CYP2D6_activity/25132101Test

المؤلفون: Ba Van Nguyen, Tho Huu Ho, Kien Xuan Dang, Ung Dinh Nguyen, Tien Viet Tran, Duc Trong Nguyen, Dung Tuan Trinh, Jakob Stenman, Nhung Thi Trang Trinh, Son Anh Ho, Luong Van Hoang, Ulf-Håkan Stenman, Quynh Huong Pham, Arto Orpana, Dung Ngoc Tran

المساهمون: HUSLAB, Department of Medical and Clinical Genetics, Helsinki University Hospital Area, Department of Clinical Chemistry and Hematology, Medicum

المصدر: BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: BRAF V600E MUTATION, 0301 basic medicine, Cancer Research, endocrine system diseases, 3122 Cancers, PAPILLARY CARCINOMAS, Biology, medicine.disease_cause, lcsh:RC254-282, Thyroid cancer, 03 medical and health sciences, symbols.namesake, NODULES, 0302 clinical medicine, Diagnosis, Genetics, medicine, Gene, neoplasms, Sanger sequencing, Mutation, Messenger RNA, Thyroid disease, B-RAF, Thyroid, mRNA mutation assay, AMPLIFICATION, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, digestive system diseases, ComputingMethodologies_PATTERNRECOGNITION, 030104 developmental biology, medicine.anatomical_structure, BRAF mutation, Oncology, 030220 oncology & carcinogenesis, Cancer research, Mutation testing, symbols, ALLELE-SPECIFIC PCR

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063fd39608e053532b45b339b1e37e2cTest
http://link.springer.com/article/10.1186/s12885-020-06862-wTest

المؤلفون: Lin Feng, Susanna Lintula, Tho Huu Ho, Maria Anastasina, Annukka Paju, Caj Haglund, Ulf-Håkan Stenman, Kristina Hotakainen, Arto Orpana, Denis Kainov, Jakob Stenman

المصدر: BioTechniques, Vol 52, Iss 4, Pp 263-270 (2012)

مصطلحات موضوعية: RT-PCR, primer-independent reverse transcription, proportion, Biology (General), QH301-705.5

العلاقة: https://doaj.org/toc/0736-6205Test; https://doaj.org/toc/1940-9818Test; https://doaj.org/article/5498c73ad25046a7b37a4fa82d7317d2Test

الإتاحة: https://doi.org/10.2144/0000113842Test
https://doaj.org/article/5498c73ad25046a7b37a4fa82d7317d2Test

المؤلفون: Arto Orpana, Heidi Asmundela, Lotta Joutsi-Korhonen, Tuukka Helin, Mikko Niemi, Riitta Lassila

المساهمون: HUSLAB, Department of Clinical Chemistry and Hematology, University of Helsinki, Department of Diagnostics and Therapeutics, Hematologian yksikkö, HUS Comprehensive Cancer Center, Department of Clinical Pharmacology, University Management, Department of Medical and Clinical Genetics

المصدر: Br J Clin Pharmacol

مصطلحات موضوعية: Male, Severity of Illness Index, 030226 pharmacology & pharmacy, ANTITHROMBIN, 0302 clinical medicine, Pharmacology (medical), 030212 general & internal medicine, RISK, Aspirin, Maintenance dose, Thrombin, Middle Aged, Thrombosis, 3. Good health, GENOTYPE, VKORC1, 317 Pharmacy, ANTICOAGULATION CONTROL, Female, Algorithms, medicine.drug, Adult, medicine.medical_specialty, Thrombophilia, Young Adult, 03 medical and health sciences, Vitamin K Epoxide Reductases, Internal medicine, medicine, Humans, Dosing, ALGORITHM, Blood Coagulation, Alleles, thrombosis, Aged, Cytochrome P-450 CYP2C9, Retrospective Studies, thrombophilia, Pharmacology, VENOUS THROMBOEMBOLISM, Polymorphism, Genetic, Dose-Response Relationship, Drug, business.industry, Warfarin, Anticoagulants, Original Articles, medicine.disease, POLYMORPHISM, warfarin, Biological Variation, Population, Pharmacodynamics, INTERNATIONAL NORMALIZED RATIO, dosing algorithm, business, GENERATION

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43e5afce8fc51649955ae934d4c209cTest
http://hdl.handle.net/10138/313832Test

المؤلفون: Terhi Jokilehto, Milja Kaare, Olli Carpén, Reetta Vainionpää, Jari Sundström, Ari Ristimäki, Minnamaija Lintunen, Arto Orpana, Pia Österlund, Raija Ristamäki, Annika Ålgars, Soili Kytölä

المصدر: International Journal of Cancer. 140:922-929

مصطلحات موضوعية: 0301 basic medicine, Oncology, Neuroblastoma RAS viral oncogene homolog, Cancer Research, medicine.medical_specialty, Colorectal cancer, medicine.disease_cause, Gene dosage, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, PIK3CA Gene Mutation, Medicine, Panitumumab, Progression-free survival, neoplasms, business.industry, Wild type, medicine.disease, digestive system diseases, 3. Good health, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, KRAS, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::6f74844755619d9879bb5b34527c1931Test
https://doi.org/10.1002/ijc.30507Test

المؤلفون: Tho Huu Ho, Mikko P. Pakarinen, Kien Xuan Dang, Arto Orpana, Antti Koivusalo, Risto Rintala, Saara J. Sistonen, Jakob Stenman, Ulf-Håkan Stenman

المساهمون: Clinicum, Children's Hospital, Lastenkirurgian yksikkö, University of Helsinki, Department of Clinical Chemistry and Hematology, Medicum, HUSLAB, Department of Medical and Clinical Genetics, Institute for Molecular Medicine Finland, HUS Children and Adolescents

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system diseases, Colorectal cancer, Biopsy, medicine.disease_cause, TRACHEOESOPHAGEAL FISTULA, Malignant transformation, COLORECTAL-CANCER, GASTROESOPHAGEAL-REFLUX, 0302 clinical medicine, 3123 Gynaecology and paediatrics, PRIMARY REPAIR, medicine.diagnostic_test, Middle Aged, medicine.anatomical_structure, Real-time polymerase chain reaction, RAS MUTATIONS, 030220 oncology & carcinogenesis, BARRETTS-ESOPHAGUS, Adenocarcinoma, Female, KRAS, Adult, Genetic Markers, Proto-Oncogene Proteins B-raf, extendable blocking probe, BRAF, Proto-Oncogene Proteins p21(ras), EVENTS, 03 medical and health sciences, Esophagus, medicine, Humans, esophageal atresia, neoplasms, TERM-FOLLOW-UP, Retrospective Studies, business.industry, ADENOCARCINOMA, medicine.disease, 3126 Surgery, anesthesiology, intensive care, radiology, digestive system diseases, 030104 developmental biology, SQUAMOUS-CELL-CARCINOMA, Atresia, Mutation, Pediatrics, Perinatology and Child Health, Cancer research, Surgery, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09930d16978c5be4fdd4d03b24f79134Test
http://hdl.handle.net/10138/311469Test

المؤلفون: Alexandra Thiel, Micaela Hernberg, Soili Kytölä, Monica Moza, Tiina Jahkola, Arto Orpana, Susanna Virolainen, Ari Ristimäki

المصدر: Human Pathology. 46:169-175

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, endocrine system diseases, Colorectal cancer, DNA Mutational Analysis, Pathology and Forensic Medicine, Biomarkers, Tumor, Humans, Medicine, Prospective Studies, Melanoma, neoplasms, business.industry, Sentinel node, medicine.disease, Immunohistochemistry, digestive system diseases, 3. Good health, Mutation, Cutaneous melanoma, Mutation (genetic algorithm), Mutation testing, Cancer research, business, V600E

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f18275f534cb8eb441b7f9b9d6f8c53Test
https://doi.org/10.1016/j.humpath.2014.08.018Test

المؤلفون: Katariina Alagrund, Arto Orpana

المصدر: Scandinavian Journal of Clinical and Laboratory Investigation. 74:44-52

مصطلحات موضوعية: Hospital information system, Genotyping Techniques, Computer science, DNA Mutational Analysis, Clinical Biochemistry, Population, Sensitivity and Specificity, Epigenesis, Genetic, Data processing system, medicine, Humans, Genetic Testing, education, Genetic testing, Automation, Laboratory, education.field_of_study, medicine.diagnostic_test, business.industry, Nucleic acid test, Robotics, General Medicine, Automation, Biotechnology, Genes, Molecular Diagnostic Techniques, Embedded system, Laboratory automation, business, Random access

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1c042cd6762f954886d3cdb19820e6Test
https://doi.org/10.3109/00365513.2013.857040Test