نتائج البحث - "Arachidonyl trifluoromethyl ketone"

1

Perilla Leaf Extract Attenuates Asthma Airway Inflammation by Blocking the Syk Pathway

المؤلفون: Hui Yang, Wei Sun, Jiqiao Yuan, Shuyi Li, Xuyu Li, Qi Hou, Fan Yannan, Mingbao Lin, Ziqian Zhang

المصدر: Mediators of Inflammation
Mediators of Inflammation, Vol 2021 (2021)

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29841066661dfcd9d0a0e69054bba82Test
https://doi.org/10.1155/2021/6611219Test

2

Inhibition of Cytosolic Phospholipase A2 Has Neuroprotective Effects on Motoneuron and Muscle Atrophy after Spinal Cord Injury

المؤلفون: Nai-Kui Liu, Qingbo Lu, James S. Byers, Dale R. Sengelaub, Xiao Ming Xu, Thomas Lam

المصدر: Journal of Neurotrauma. 38:1327-1337

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c6b8d685d6cd49a9250f058431c0c04fTest
https://doi.org/10.1089/neu.2014.3690Test

3

A Multiplex CRISPR-Screen Identifies PLA2G4A as Prognostic Marker and Druggable Target for HOXA9 and MEIS1 Dependent AML

المؤلفون: Axel Schambach, Adrian Schwarzer, Anna Lieske, Denise Klatt, Nicole Dörpmund, Olga S. Kustikova, Maike Stahlhut, Marc-Jens Kleppa, Dirk Hoffmann, Tobias Maetzig, Jacob Jalil Hassan

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 9411, p 9411 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 17

مصطلحات موضوعية: Pla2g4a, Candidate gene, Krebsrisiko, Apoptosis, Small hairpin RNA, shRNA, hemic and lymphatic diseases, Gene expression, Tumor Cells, Cultured, CRISPR, Biology (General), Myeloid Ecotropic Viral Integration Site 1 Protein, Meis1, Spectroscopy, multiplexing, Myeloid leukemia, General Medicine, leukemic stem cell, Computer Science Applications, Gene Expression Regulation, Neoplastic, Leukemia, Myeloid, Acute, Chemistry, Akute myeloische Leukämie, QH301-705.5, Biology, acute myeloid leukemia, Article, Catalysis, Viral vector, Inorganic Chemistry, Biomarkers, Tumor, Hoxa9, Humans, ddc:610, Physical and Theoretical Chemistry, Molecular Biology, neoplasms, QD1-999, Cell Proliferation, Homeodomain Proteins, Arachidonyl trifluoromethyl ketone, CRISPR/Cas-Methode, Group IV Phospholipases A2, fluorescent genetic barcoding, lentiviral vector, Organic Chemistry, PLA2G4A, High-Throughput Screening Assays, 610 Medizin, Gesundheit, Genexpression, Cancer research, biology.protein, CRISPR-Cas Systems

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cab0238ea386bce838a0397176b23cTest
https://www.mdpi.com/1422-0067/22/17/9411Test

4

تقرير

Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats

المؤلفون: Khan, Mushfiquddin, Shunmugavel, Anandakumar, Dhammu, Tajinder S, Matsuda, Fumiyo, Singh, Avtar K, Singh, Inderjit

مصطلحات موضوعية: Lumbar spinal canal stenosis, Cauda equina compression, Cytosolic phospholipase A2, Neuroinflammation, Arachidonyl trifluoromethyl ketone, Pain, Motor function

العلاقة: http://www.jneuroinflammation.com/content/12/1/94Test

الإتاحة: http://www.jneuroinflammation.com/content/12/1/94Test

View record in BASE

5

Unique regulation of Na-glutamine cotransporter SN2/SNAT5 in rabbit intestinal crypt cells during chronic enteritis

المؤلفون: Subha Arthur, Uma Sundaram, Soudamani Singh

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Leukotrienes, Indoles, Glutamine, Lipoxygenase, SN2/SNAT5, Crypt, Glutamine transport, Stimulation, Arachidonic Acids, Pharmacology, 03 medical and health sciences, 0302 clinical medicine, Ileum, Animals, Lipoxygenase Inhibitors, Enzyme Inhibitors, Arachidonyl trifluoromethyl ketone, Leukotriene, Arachidonic Acid, biology, Coccidiosis, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Sodium, Original Articles, Cell Biology, Enteritis, prostaglandins and crypt cells, 3. Good health, Amino Acid Transport Systems, Neutral, 030104 developmental biology, Gene Expression Regulation, Prostaglandin-Endoperoxide Synthases, Chronic Disease, biology.protein, Molecular Medicine, Eimeria, Original Article, 030211 gastroenterology & hepatology, Rabbits, Cyclooxygenase, Cotransporter

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3094ffb3273d2a6ff095ab1feaf6bfTest
https://doi.org/10.1111/jcmm.13257Test

6

A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A2

المؤلفون: Wee Yong Ong, Yulin Lam, Mei-Lin Go, Yong Jun Chen, Francis Chee Kuan Tan, Chandra S. Verma, Chian-Ming Low, Srinivasaraghavan Kannan, Cheng Yang Ng

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01798ee664b60960be748a5d1326f3b2Test
http://link.springer.com/article/10.1038/s41598-017-13996-8Test

7

Reactive oxygen species facilitate the EDH response in arterioles by potentiating intracellular endothelial Ca2+ release

المؤلفون: Chidgey, James, Fraser, Paul A., Aaronson, Philip I.

المصدر: Chidgey, J, Fraser, P A & Aaronson, P I 2016, ' Reactive oxygen species facilitate the EDH response in arterioles by potentiating intracellular endothelial Ca2+ release ', Free Radical Biology and Medicine . https://doi.org/10.1016/j.freeradbiomed.2016.06.010Test
Free Radical Biology & Medicine

مصطلحات موضوعية: Male, H2O2, PGI2, prostacyclin, L-NNA, Nω-Nitro-l-arginine, IP3R, IP3 receptor, arteriole, Biochemistry, VSMC, vascular smooth muscle cell, IBTx, Iberiotoxin, Membrane Potentials, Biological Factors, AACOCF3, arachidonyl trifluoromethyl ketone, EDHR, EDH response, IL-1⍰, interleukin-1β, Arteriole, vasodilation, CPA, Cyclopiazonic Acid, reactive oxygen species, EDH, endothelial dependent hyperpolarization, Endothelium dependent hyperpolarization, cPLA2, cytoplasmic PLA2, Vasodilation, CP85, Na-1-ethylsulfoxide-2-methyl-3-hyroxypyridin-4-one, Arterioles, Ca2+, ODYA, 17-octadecynoic acid, S&C, SOD and catalase, sEH, epoxide hydrolase, EDHF, EDH factor, Muscarinic Agonists, PPOH, 2-(2-propynyloxy)-benzenehexanoic acid, Article, DFO, Desferrioxamine, PLC, phospholipase C, ROS, reactive oxygen species, SOD, superoxide dismutase, Physiology (medical), Animals, Calcium Signaling, Rats, Wistar, NO, nitric oxide, EETs, epoxyeicosatrienoic acids, EEZE, 4, 15-epoxyeicosa-5(Z)-enoic acid, PE, phenylephrine, EC, endothelial cell, PSS, physiological salt solution, PLA2, phospholipase A2, CP94, 1,2-diethyl-3-hyroxypyridin-4-one, HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid, Hydrogen Peroxide, AUDA, 12-(3-adamantan-1-yl-ureido)dodecanoic acid, PKG, protein kinase G, Carbachol, EGTA, ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid, Endothelium, Vascular, Reactive oxygen species, L-NAME, N(G)-nitro-l-arginine methyl ester, SERCA, sarcoplasmic reticulum Ca2+-ATPase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::738f934f8eafceecdae9bc503def72ebTest

8

Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment

المساهمون: Saulnier-Blache, Jean Sébastien, Systems Biology to Identify Molecular Targets for Vascular Disease Treatment - SYSVASC - - EC:FP7:HEALTH2014-02-01 - 2018-01-31 - 603288 - VALID, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Biomedical Research Foundation of the Academy of Athens, German Center for Cardiovascular Research (DZHK), Berlin Institute of Health (BIH), Mosaiques Diagnostics GmbH, Johannes Kepler University Linz [Linz] (JKU), Karl-Franzens-Universität Graz, University of Glasgow, University of Tübingen, Diabète athérothrombose et thérapies Réunion Océan Indien (DéTROI), Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by the European Union Seventh Framework Program (FP7/2007-2013–603288- SysVasc, to JPS, VL, SVL, CD, FL, BP, JLP, HM, JSSB, JV, AV, and JL), the European Union ERA CVD JTC2017 PROACT (ANR-17-ECVD-0006 to JK, GF, CD, JSSB, and JPS, 01KL1805 via the Federal Ministry of Education and Research to HM), INSERM, the 'Fondation pour la Recherche Médicale' (grant DEQ20170336759 to JK, GF, CD, JSSB and JPS), the British Heart Foundation Centre of Research Excellence Award (RE/13/5/30177), the Deutsche Forschungsgemeinschaft (AL2054/1-1, VO2259/2-1), the Berlin Institute of Health, and the Else Kröner-Fresenius-Stiftung to TTDL, JV, IA, BB, and NS. Immunopathological analysis of cPLA2 was provided by the iPATH.Berlin – Core Unit Immunopathology for Experimental Models of the Charité – Universitätsmedizin Berlin (Berlin, Germany)., European Project: 603288,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,SYSVASC(2014), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Karl-Franzens-Universität [Graz, Autriche], Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de La Réunion (UR), Charité - Universitätsmedizin Berlin / Charite - University Medicine Berlin, Academy of Athens, University of Graz, BHF Glasgow Cardiovascular Research Centre, University of Glasgow-Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre (BHF GCRC), Department of Physiology, Eberhard Karls Universität Tübingen, Charité Campus Virchow-Klinikum (CVK), Institute of Cardiovascular and Medical Sciences [Glasgow], Institut de médecine moléculaire de Rangueil (I2MR), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IFR150-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Fédérale Toulouse Midi-Pyrénées, Biomedical Research Foundation of the Academy of Athens (BRFAA), Mosaiques Diagnostics GmbH [Hannover, Germany], Mosaiques Diagnostics and Therapeutics AG [Hannover, Germany], Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Johannes Kepler Universität Linz - Johannes Kepler University Linz [Autriche] (JKU)

المصدر: JCI Insight
JCI Insight, 2019, 4 (10), pp.125638. ⟨10.1172/jci.insight.125638⟩
JCI Insight, American Society for Clinical Investigation, 2019, 4 (10), pp.125638. ⟨10.1172/jci.insight.125638⟩
JCI Insight, American Society for Clinical Investigation, 2019, 4 (10), pp.e125638. ⟨10.1172/jci.insight.125638⟩

مصطلحات موضوعية: 0301 basic medicine, Male, [SDV]Life Sciences [q-bio], Mice, [SCCO]Cognitive science, 0302 clinical medicine, Cytosol, Medicine, media_common, Mice, Knockout, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, biology, Systems Biology, General Medicine, Middle Aged, Cardiovascular disease, 3. Good health, Up-Regulation, Cardiovascular Diseases, 030220 oncology & carcinogenesis, Proteome, Female, Research Article, Drug, Adult, Systems biology, media_common.quotation_subject, Myocytes, Smooth Muscle, Arachidonic Acids, 03 medical and health sciences, Phospholipase A2, Apolipoproteins E, Downregulation and upregulation, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, In vivo, Vascular Biology, Animals, Humans, Antigens, Human Platelet, Atherosclerosis, Cardiovascular disease, Vascular Biology, Vascular Calcification, Arachidonyl trifluoromethyl ketone, business.industry, [SCCO] Cognitive science, Atherosclerosis, In vitro, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, biology.protein, Cancer research, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362498f808f165d0218c5a057d0801d4Test
https://www.hal.inserm.fr/inserm-02444365Test

9

Inhibition of PLA2G4A Reduces the Expression of Lung Cancer-Related Cytokines

المؤلفون: Xiumei Wang, Minghua Sui, Xuan Zhao, Weiwei Zhang, Liangming Zhang, Dengjun Sun, Jing Jiang, Chunxia Xin, Yanchun Wang, Ping Sui, Dongmei Geng

المصدر: DNA and cell biology.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a572209044a3e202c509c5f95bdec27bTest
https://pubmed.ncbi.nlm.nih.gov/30328712Test

10

Effects of Phospholipase A2 Inhibitors on Bilayer Lipid Membranes

المؤلفون: Mikhail V. Dubinin, Igor A. Dyachenko, Konstantin N. Belosludtsev, Maxim E. Astashev, Nikita V. Penkov, Victor N. Samartsev, Sergey V. Gudkov

المصدر: The Journal of Membrane Biology. 249:339-347

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7255d2047a5759cabc2b9d31ceef307Test
https://doi.org/10.1007/s00232-016-9872-7Test

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