المؤلفون: Seneviratne, Anusha, Cave, Luke, Hyde, Gareth, Moestrup, Soren Kragh, Carling, David, Mason, Justin C., Haskard, Dorian O., Boyle, Joseph James

المصدر: Seneviratne , A , Cave , L , Hyde , G , Moestrup , S K , Carling , D , Mason , J C , Haskard , D O & Boyle , J J 2021 , ' Metformin directly suppresses atherosclerosis in normoglycaemic mice via haematopoietic adenosine monophosphate-activated protein kinase ' , Cardiovascular Research , vol. 117 , no. 5 , pp. 1295-1308 . https://doi.org/10.1093/cvr/cvaa171Test

مصطلحات موضوعية: AMPK, Atherosclerosis, Gene expression, Macrophage, Metformin, Transcription factor, ACCELERATED ATHEROSCLEROSIS, BONE-MARROW-TRANSPLANTATION, MACROPHAGES, TRANSCRIPTION, RECEPTOR, HEART-DISEASE, HEME, PATHWAY, MONOCYTE SUBSETS, EXPRESSION, Phosphorylation, Humans, Aortic Diseases/enzymology, Aorta/drug effects, Atherosclerosis/enzymology, Receptors, LDL/genetics, AMP-Activated Protein Kinases/genetics, Disease Models, Animal, Signal Transduction, Metformin/pharmacology, Cells, Cultured

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1093/cvr/cvaa171Test
https://pure.au.dk/portal/da/publications/metformin-directly-suppresses-atherosclerosis-in-normoglycaemic-mice-via-haematopoietic-adenosine-monophosphateactivated-protein-kinaseTest(85ce7ecf-04fc-41c3-957e-86935662d77a).html
https://pure.au.dk/ws/files/274450570/cvaa171.pdfTest
http://www.scopus.com/inward/record.url?scp=85104037249&partnerID=8YFLogxKTest

المؤلفون: Le Gal, L., Pellegrin, M., Santoro, T., Mazzolai, L., Kurtz, A., Meda, P., Wagner, C., Haefliger, J.A.

المصدر: Journal of the American Heart Association, vol. 8, no. 8, pp. e010823

مصطلحات موضوعية: Angiotensin II/pharmacology, Animals, Aorta/cytology, Aorta/drug effects, Aorta/metabolism, Blood Pressure/drug effects, Blood Pressure/genetics, Connexins/genetics, Disease Models, Animal, Endothelial Cells/metabolism, Enzyme Inhibitors/pharmacology, Extracellular Signal-Regulated MAP Kinases/metabolism, Hypertension/genetics, Hypertension/metabolism, Male, Mice, Knockout, Muscle, Smooth, Vascular/cytology, Myocytes, Smooth Muscle/metabolism, Myosin Light Chains/metabolism, NG-Nitroarginine Methyl Ester/pharmacology, Protein Tyrosine Phosphatase, Non-Receptor Type 6/genetics, Proto-Oncogene Proteins c-akt/metabolism, Receptor, Angiotensin

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30943815; info:eu-repo/semantics/altIdentifier/eissn/2047-9980; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_C1CFAC6BE88D0; https://serval.unil.ch/notice/serval:BIB_C1CFAC6BE88DTest; urn:issn:2047-9980; https://serval.unil.ch/resource/serval:BIB_C1CFAC6BE88D.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C1CFAC6BE88D0Test

الإتاحة: https://doi.org/10.1161/JAHA.118.010823Test
https://serval.unil.ch/notice/serval:BIB_C1CFAC6BE88DTest
https://serval.unil.ch/resource/serval:BIB_C1CFAC6BE88D.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C1CFAC6BE88D0Test

المؤلفون: Yang, Guliang, Lin, Chi-Chen, Yang, Yiwen, Yuan, Li, Wang, Peilei, Wen, Xiang, Pan, Min-Hsiung, Zhao, Hui, Ho, Chi-Tang, Li, Shiming

المصدر: Journal of Agricultural and Food Chemistry, 67 (22), 6169 - 6176 (2019-06-05)

مصطلحات موضوعية: NF-κB/MAPK pathways, TMAO, cell proliferation, nobiletin, vascular inflammation, Flavones, Methylamines, Transcription Factor RelA, Mitogen-Activated Protein Kinase Kinases, trimethyloxamine, Animals, Aorta/drug effects, Aorta/immunology, Female, Flavones/administration & dosage, Human Umbilical Vein Endothelial Cells, Humans, Liver/drug effects, Liver/immunology, Male, Methylamines/adverse effects, Mitogen-Activated Protein Kinase Kinases/genetics, Mitogen-Activated Protein Kinase Kinases/immunology, Rats, Rats, Sprague-Dawley, Transcription Factor RelA/genetics, Transcription Factor RelA/immunology, Vascular Diseases/chemically induced, Vascular Diseases/genetics, Vascular Diseases/immunology, Vascular Diseases/prevention & control, General Agricultural and Biological Sciences, General Chemistry, Life sciences, Food science, Sciences du vivant, Sciences des denrées alimentaires

العلاقة: https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.9b01270Test; urn:issn:0021-8561; urn:issn:1520-5118

الوصول الحر: https://orbi.uliege.be/handle/2268/316051Test

المؤلفون: Gravesen, Eva, Lerche Mace, Maria, Nordholm, Anders, Hofman-Bang, Jacob, Hruska, Keith, Haagen Nielsen, Carsten, Kjær, Andreas, Olgaard, Klaus, Lewin, Ewa

المصدر: Gravesen , E , Lerche Mace , M , Nordholm , A , Hofman-Bang , J , Hruska , K , Haagen Nielsen , C , Kjær , A , Olgaard , K & Lewin , E 2018 , ' Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification ' , PLOS ONE , vol. 13 , no. 1 , e0190820 . https://doi.org/10.1371/journal.pone.0190820Test

مصطلحات موضوعية: Animals, Aorta/drug effects, Bone Morphogenetic Protein 7/pharmacology, Chronic Disease, Fibrosis, Gene Expression Regulation/drug effects, Male, Phosphates/blood, Rats, Real-Time Polymerase Chain Reaction, Uremia/drug therapy, Vascular Calcification/drug therapy, X-Ray Microtomography

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1371/journal.pone.0190820Test
https://curis.ku.dk/portal/da/publications/exogenous-bmp7-in-aortae-of-rats-with-chronic-uremia-ameliorates-expression-of-profibrotic-genes-but-does-not-reverse-established-vascular-calcificationTest(ac6d3279-f25d-4685-8a4f-5d1c8571db42).html
https://curis.ku.dk/ws/files/213000598/journal.pone.0190820.pdfTest

المساهمون: College of Medicine, Dept. of Anesthesiology and Pain Medicine, Hyo-Jin Byon, Seong-Ho Ok, Soo Hee Lee, Sebin Kang, Youngil Cho, Jeong Yeol Han, Ju-Tae Sohn, Byon, Hyo Jin

مصطلحات موضوعية: Adrenergic Agonists/pharmacology, Animals, Aorta/drug effects, Aorta/metabolism, Dexmedetomidine/pharmacology, In Vitro Techniques, Male, Muscle Contraction/drug effects, Nitric Oxide/metabolism, Phenoxybenzamine/pharmacology, Phenylephrine/pharmacology, Rats, Receptors, Adrenergic/metabolism, Serotonin/pharmacology, alpha-1 adrenoceptor, alpha-2 adrenoceptor agonist, aorta, contraction, dexmedetomidine, nitric oxide, phenoxybenzamine, phentolamine, phenylephrine

العلاقة: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES; J02917; OAK-2017-04428; https://ir.ymlib.yonsei.ac.kr/handle/22282913/160686Test; T201703052; INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, Vol.14(2) : 143-149, 2017

الإتاحة: https://doi.org/10.7150/ijms.17456Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160686Test

المؤلفون: David Carling, Dorian O. Haskard, Søren K. Moestrup, Justin C. Mason, L. Cave, Joseph J. Boyle, A. Seneviratne, Gareth Hyde

المساهمون: British Heart Foundation

المصدر: Seneviratne, A, Cave, L, Hyde, G, Moestrup, S K, Carling, D, Mason, J C, Haskard, D O & Boyle, J J 2021, ' Metformin directly suppresses atherosclerosis in normoglycaemic mice via haematopoietic adenosine monophosphate-activated protein kinase ', Cardiovascular Research, vol. 117, no. 5, pp. 1295-1308 . https://doi.org/10.1093/cvr/cvaa171Test
Cardiovascular Research

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, AMPK, HMOX1, endocrine system diseases, Physiology, Macrophage, 030204 cardiovascular system & hematology, AMP-Activated Protein Kinases, PATHWAY, 0302 clinical medicine, Macrophages/drug effects, Metformin/pharmacology, Receptors, LDL/genetics, AcademicSubjects/MED00200, Aorta/drug effects, TRANSCRIPTION, MACROPHAGES, Phosphorylation, AMP-Activated Protein Kinases/genetics, 1102 Cardiorespiratory Medicine and Haematology, Aorta, Cells, Cultured, Mice, Knockout, Gene knockdown, biology, Chemistry, HEME, Metformin, Plaque, Atherosclerotic, Haematopoiesis, Phenotype, Cardiology and Cardiovascular Medicine, Platelet-derived growth factor receptor, medicine.drug, Signal Transduction, EXPRESSION, Activating Transcription Factor 1/genetics, Aortic Diseases/enzymology, Aortic Diseases, HEART-DISEASE, 03 medical and health sciences, Physiology (medical), medicine, Atherosclerosis and Lipid Biology, Humans, Animals, Activating Transcription Factor 1, RECEPTOR, Macrophages, nutritional and metabolic diseases, Original Articles, Atherosclerosis, Atherosclerosis/enzymology, BONE-MARROW-TRANSPLANTATION, Disease Models, Animal, 030104 developmental biology, Cardiovascular System & Hematology, Receptors, LDL, Gene Expression Regulation, ABCA1, biology.protein, Cancer research, Gene expression, Transcription factor, MONOCYTE SUBSETS, ACCELERATED ATHEROSCLEROSIS

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2da685d70a2d1fb7b288da50784ff2aTest
https://pure.au.dk/portal/da/publications/metformin-directly-suppresses-atherosclerosis-in-normoglycaemic-mice-via-haematopoietic-adenosine-monophosphateactivated-protein-kinaseTest(85ce7ecf-04fc-41c3-957e-86935662d77a).html

المساهمون: College of Medicine, Dept. of Thoracic & Cardiovascular Surgery, Chang Kuk Choi, Kang Ju Lee, Young Nam Youn, Eui Hwa Jang, Woong Kim, Byung-Kwon Min, WonHyoung Ryu, Youn, Young Nam

مصطلحات موضوعية: Animals, Aorta/drug effects, Dogs, Drug Delivery Systems/instrumentation, Drug Delivery Systems/methods, Microinjections/instrumentation, Microinjections/methods, Needles, Polymers/administration & dosage, Temperature, Biodegradable polymers, Drug delivery, Microneedles, Thermal drawing, Vascular tissue

العلاقة: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS; J00841; OAK-2012-03231; https://ir.ymlib.yonsei.ac.kr/handle/22282913/158251Test; https://www.sciencedirect.com/science/article/pii/S0939641112003463Test; T201204988; EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, Vol.83(2) : 224-233, 2013

الإتاحة: https://doi.org/10.1016/j.ejpb.2012.10.020Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/158251Test
https://www.sciencedirect.com/science/article/pii/S0939641112003463Test

المساهمون: Jae-Hoon Choi, Cheolho Cheong, Durga B. Dandamudi, Chae Gyu Park, Anthony Rodriguez, Saurabh Mehandru, Klara Velinzon, In-Hyuk Jung, Ji-Young Yoo, Goo Taeg Oh, Ralph M. Steinman, Park, Chae Gyu

مصطلحات موضوعية: Animals, Antigens, CD/metabolism, Aorta/drug effects, Aorta/immunology, Atherosclerosis/genetics, Atherosclerosis/immunology, Atherosclerosis/pathology, Dendritic Cells/drug effects, Dendritic Cells/immunology, Dendritic Cells/metabolism, Gene Expression Regulation/immunology, Leukocyte Reduction Procedures, Macrophage Colony-Stimulating Factor/metabolism, Macrophages/immunology, Membrane Proteins/pharmacology, Mice, Inbred BALB C, Inbred C57BL, Knockout, Monocytes/immunology, Signal Transduction, fms-Like Tyrosine Kinase 3/genetics, fms-Like Tyrosine Kinase 3/metabolism

وصف الملف: 819~831

العلاقة: IMMUNITY; J01034; OAK-2011-02888; https://ir.ymlib.yonsei.ac.kr/handle/22282913/95414Test; http://www.sciencedirect.com/science/article/pii/S1074761311004560Test; T201194239; IMMUNITY, Vol.35(5) : 819-831, 2011

الإتاحة: https://doi.org/10.1016/j.immuni.2011.09.014Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95414Test
http://www.sciencedirect.com/science/article/pii/S1074761311004560Test

المساهمون: Kevin G. Soucy, Hyun Kyo Lim, Jae Hyung Kim, Young Oh, David O. Attarzadeh, Baris Sevinc, Maggie M. Kuo, Artin A. Shoukas, Marcelo E. Vazquez, Dan E. Berkowitz, Oh, Young Jun

مصطلحات موضوعية: Animals, Aorta/drug effects, Aorta/pathology, Aorta/radiation effects, Biomechanical Phenomena, Endothelium, Vascular/drug effects, Vascular/enzymology, Vascular/metabolism, Vascular/radiation effects, Enzyme Inhibitors/pharmacology, Iron/adverse effects, Male, Nitric Oxide/biosynthesis, Oxypurinol/pharmacology, Rats, Wistar, Reactive Oxygen Species/metabolism, Time Factors, Whole-Body Irradiation/adverse effects, Xanthine Oxidase/antagonists & inhibitors, Xanthine Oxidase/metabolism

وصف الملف: 474~485

العلاقة: RADIATION RESEARCH; J02593; OAK-2011-01918; https://ir.ymlib.yonsei.ac.kr/handle/22282913/94444Test; T201103610; RADIATION RESEARCH, Vol.176(4) : 474-485, 2011

الإتاحة: https://doi.org/10.1667/RR2598.1Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94444Test

المؤلفون: Alonso, F., Krattinger, N., Mazzolai, L., Simon, A., Waeber, G., Meda, P., Haefliger, J.A.

المصدر: Cardiovascular Research, vol. 87, no. 1, pp. 166-176

مصطلحات موضوعية: Angiotensin II/metabolism, Angiotensin II Type 1 Receptor Blockers/pharmacology, Angiotensin-Converting Enzyme Inhibitors/pharmacology, Animals, Antihypertensive Agents/pharmacology, Aorta/drug effects, Aorta/metabolism, Binding Sites, Blood Pressure, Carotid Arteries/metabolism, Carotid Arteries/physiopathology, Cell Line, Connexin 43/genetics, Connexin 43/metabolism, Connexins/deficiency, Connexins/genetics, Disease Models, Animal, Endothelial Cells/metabolism, Extracellular Signal-Regulated MAP Kinases/metabolism, Genes, Reporter, Hypertension, Renovascular/drug therapy, Renovascular/etiology, Mesenteric Arteries/metabolism, Mesenteric Arteries/physiopathology, Mice, Inbred C57BL, Knockout

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/20110337; info:eu-repo/semantics/altIdentifier/pissn/1755-3245[electronic], 0008-6363[linking]; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_C5BA88DA7FAC4; https://serval.unil.ch/notice/serval:BIB_C5BA88DA7FACTest; https://serval.unil.ch/resource/serval:BIB_C5BA88DA7FAC.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C5BA88DA7FAC4Test

الإتاحة: https://doi.org/10.1093/cvr/cvq031Test
https://serval.unil.ch/notice/serval:BIB_C5BA88DA7FACTest
https://serval.unil.ch/resource/serval:BIB_C5BA88DA7FAC.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C5BA88DA7FAC4Test