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1دورية أكاديمية
المؤلفون: Daqi Tu, Zehua Zhu, Alicia Y. Zhou, Cai-hong Yun, Kyung-Eun Lee, Angela V. Toms, Yiqun Li, Gavin P. Dunn, Edmond Chan, Tran Thai, Shenghong Yang, Scott B. Ficarro, Jarrod A. Marto, Hyesung Jeon, William C. Hahn, David A. Barbie, Michael J. Eck
المصدر: Cell Reports, Vol 3, Iss 3, Pp 747-758 (2013)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124713000570Test; https://doaj.org/toc/2211-1247Test
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المؤلفون: Silvana Leit, Jeremy R. Greenwood, Sayan Mondal, Samantha Carriero, Markus Dahlgren, Geraldine C. Harriman, Joshua J. Kennedy-Smith, Rosana Kapeller, Jon P. Lawson, Donna L. Romero, Angela V. Toms, Mee Shelley, Ronald T. Wester, William Westlin, Joshua J. McElwee, Wenyan Miao, Scott D. Edmondson, Craig E. Masse
المصدر: Bioorganicmedicinal chemistry letters. 73
مصطلحات موضوعية: TYK2 Kinase, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Rodentia, Biochemistry, Mice, Drug Discovery, Molecular Medicine, Animals, Humans, Psoriasis, Molecular Biology, Protein Kinase Inhibitors, Janus Kinases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437201685fd71738ea69d006bd5f028bTest
https://pubmed.ncbi.nlm.nih.gov/35842205Test -
3دورية أكاديمية
المؤلفون: Randall McNally, Angela V Toms, Michael J Eck
المصدر: PLoS ONE, Vol 11, Iss 5, p e0156218 (2016)
العلاقة: http://europepmc.org/articles/PMC4881981?pdf=renderTest; https://doaj.org/toc/1932-6203Test; https://doaj.org/article/89656fd5c0c64810a6a79f194c029f46Test
الإتاحة: https://doi.org/10.1371/journal.pone.0156218Test
https://doaj.org/article/89656fd5c0c64810a6a79f194c029f46Test -
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المؤلفون: Jian Lin, M. Katz, S. Ashwell, A.M. Campbell, K.J. Barr, Mark T. Kershaw, Wei Lu, D. Walker, Zhongguo Wang, Angela V. Toms, L. Yao, A. Clarke, R.B. Diebold, H.R. Josephine, Deepali Gotur, A. Ericsson, Christopher J. Dinsmore, G.R. Gustafson, Caravella Justin Andrew, Jennifer Castro
المصدر: Journal of Medicinal Chemistry. 63:1612-1623
مصطلحات موضوعية: IDH1, Pyridines, Mutant, Antineoplastic Agents, Quinolones, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, Structure–activity relationship, Enzyme Inhibitors, 030304 developmental biology, ADME, Mice, Inbred BALB C, 0303 health sciences, Molecular Structure, Chemistry, Quinoline, Oxidoreductase inhibitor, Xenograft Model Antitumor Assays, Isocitrate Dehydrogenase, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Cell culture, Drug Design, Quinolines, Cancer research, Molecular Medicine, Female, Drug Screening Assays, Antitumor, Penetrant (biochemical), Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0965a9edfde187ce8dfcfe433ff8a562Test
https://doi.org/10.1021/acs.jmedchem.9b01423Test -
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المؤلفون: Jesse M Hansen, Joshua J McElwee, Eric M. Lynch, Kevin D Kreutter, Gydo C. P. van Zundert, Michael A. DiMattia, Joel Quispe, Andreas Verras, Steven K. Albanese, Neelu Kaila, Justin M. Kollman, Angela V. Toms, Madison Arza Kennedy, Kenneth W. Borrelli
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: Gene isoform, Cytidine triphosphate, T-Lymphocytes, enzymes, Biochemistry, Nucleoside salvage, chemistry.chemical_compound, immune disorders, Humans, Protein Isoforms, Carbon-Nitrogen Ligases, CTP binding, CTP synthase, Cell Proliferation, chemistry.chemical_classification, Multidisciplinary, ATP synthase, biology, Drug discovery, Immunologic Deficiency Syndromes, Biological Sciences, small molecules, Enzyme, chemistry, biology.protein, Nucleic acid, cryo-EM
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e970023a4f204df8bc5bb1e49ba04c6Test
https://doi.org/10.1073/pnas.2107968118Test -
6
المؤلفون: Fred Csibi-Levin, Silvana Leit, David L. Laughton, Tom Baker, Suzanne L. Jacques, Beth Browning, Angela V. Toms, Samantha Garside, Simon D'Archivio, Katarzyna Kopycka, Xiaohua Zhu, Allan M. Jordan, Stuart Thomson, Christine Loh, Peter Tummino, David N. Ciccone
المصدر: Cancer Research. 82:589-589
مصطلحات موضوعية: Cancer Research, Oncology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::53a52ecbb63015d93d013097f6369635Test
https://doi.org/10.1158/1538-7445.am2022-589Test -
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المؤلفون: Zhongguo Wang, Goss Stryker Kauffman, Stephen Hubbs, Shawn Fessler, Lili Yao, Jennifer Castro, George P. Luke, Lu Wei, Mark T. Kershaw, Matthew W. Martin, Shawn Schiller, Crystal McKinnon, Angela V. Toms, Kenneth W. Bair, David S. Millan, David R. Lancia, Deepali Gotur, Li Hongbin
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:1001-1006
مصطلحات موضوعية: Cellular activity, High-throughput screening, Clinical Biochemistry, Drug Evaluation, Preclinical, Administration, Oral, Mice, Nude, Pharmaceutical Science, 01 natural sciences, Biochemistry, Piperazines, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, Transferase, Binding site, Molecular Biology, Cell Proliferation, Binding Sites, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Protein Structure, Tertiary, Rats, 0104 chemical sciences, Malonyl Coenzyme A, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Fatty acid synthase, Lipogenesis, biology.protein, Molecular Medicine, Fatty Acid Synthases, Half-Life
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e1607021e1e0b594aba77304e55e00Test
https://doi.org/10.1016/j.bmcl.2019.02.012Test -
8دورية أكاديمية
المؤلفون: Daqi Tu, Yiqun Li, Hyun Kyu Song, Angela V Toms, Christopher J Gould, Scott B Ficarro, Jarrod A Marto, Bruce L Goode, Michael J Eck
المصدر: PLoS ONE, Vol 6, Iss 3, p e18080 (2011)
العلاقة: http://europepmc.org/articles/PMC3061879?pdf=renderTest; https://doaj.org/toc/1932-6203Test; https://doaj.org/article/3e1213b7b7234af680f68a6be46937f2Test
الإتاحة: https://doi.org/10.1371/journal.pone.0018080Test
https://doaj.org/article/3e1213b7b7234af680f68a6be46937f2Test -
9دورية أكاديمية
المؤلفون: Rock I, Daqi Tu, Yiqun Li, Hyun Kyu Song, Angela V. Toms, Christopher J. Gould, Scott B. Ficarro, Jarrod A. Marto, Bruce L. Goode, Michael J. Eck
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/34/36/PLoS_One_2011_Mar_21_6(3)_e18080.tar.gz
وصف الملف: application/zip
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المؤلفون: K.J. Barr, A. Ericsson, Zhongguo Wang, David R. Lancia, A. Clarke, R.B. Diebold, S. Ashwell, George P. Luke, Deepali Gotur, Wei Lu, Jian Lin, H.R. Josephine, M. Katz, D. Walker, A.M. Campbell, Goss Stryker Kauffman, L. Yao, Angela V. Toms, Caravella Justin Andrew, H. Diep, Jennifer Castro, Kenneth W. Bair, E. Fritzen, Christopher J. Dinsmore, Stephen Hubbs, Le Wang, G.R. Gustafson, Tatiana E. Shelekhin, Mark T. Kershaw
المصدر: Journal of medicinal chemistry. 62(14)
مصطلحات موضوعية: Models, Molecular, IDH1, Allosteric regulation, Biological Availability, Pharmacology, Quinolones, Crystallography, X-Ray, 01 natural sciences, Madin Darby Canine Kidney Cells, 03 medical and health sciences, Mice, Dogs, Cell Line, Tumor, Drug Discovery, Animals, Humans, Point Mutation, Enzyme Inhibitors, 030304 developmental biology, ADME, 0303 health sciences, Mice, Inbred BALB C, Chemistry, Drug discovery, Myeloid leukemia, Oxidoreductase inhibitor, Small molecule, Isocitrate Dehydrogenase, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Isocitrate dehydrogenase, Molecular Medicine, Female, Allosteric Site
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74eee5a37b35c08111cdd42f3f0e0830Test
https://pubmed.ncbi.nlm.nih.gov/31199148Test