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1دورية أكاديمية
المؤلفون: Giuseppe Deganutti, Yi-Lynn Liang, Xin Zhang, Maryam Khoshouei, Lachlan Clydesdale, Matthew J. Belousoff, Hari Venugopal, Tin T. Truong, Alisa Glukhova, Andrew N. Keller, Karen J. Gregory, Katie Leach, Arthur Christopoulos, Radostin Danev, Christopher A. Reynolds, Peishen Zhao, Patrick M. Sexton, Denise Wootten
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
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المؤلفون: Andrew N. Keller, Tracy M. Josephs, Karen J. Gregory, Katie Leach
المصدر: GPCRs as Therapeutic Targets. :580-630
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d474ec5c2b755b622ab0a10dbe8af361Test
https://doi.org/10.1002/9781119564782.ch17Test -
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المؤلفون: Lachlan Clydesdale, Hari Venugopal, Peishen Zhao, Patrick M. Sexton, Alisa Glukhova, Arthur Christopoulos, Christopher A. Reynolds, Yi Lynn Liang, Xin Zhang, Tin T. Truong, Andrew N. Keller, Maryam Khoshouei, Matthew J. Belousoff, Karen J. Gregory, Giuseppe Deganutti, Radostin Danev, Denise Wootten, Katie Leach
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Nature Communicationsمصطلحات موضوعية: Protein Conformation, alpha-Helical, Gene Expression, General Physics and Astronomy, Peptide, Ligands, chemistry.chemical_compound, Receptor pharmacology, G protein-coupled receptors, Glucagon-Like Peptide 1, Cloning, Molecular, Receptor, chemistry.chemical_classification, Multidisciplinary, digestive, oral, and skin physiology, Recombinant Proteins, Transmembrane domain, Oxyntomodulin, Baculoviridae, hormones, hormone substitutes, and hormone antagonists, Protein Binding, Agonist, endocrine system, medicine.drug_class, G protein, Science, Genetic Vectors, Allosteric regulation, Molecular Dynamics Simulation, Glucagon-Like Peptide-1 Receptor, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, Allosteric Regulation, Electron microscopy, medicine, Humans, Protein Interaction Domains and Motifs, Binding Sites, Cryoelectron Microscopy, Mutagenesis, General Chemistry, Kinetics, HEK293 Cells, chemistry, Mutation, Biophysics, Exenatide, Protein Conformation, beta-Strand
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5aa9dcac923a091ce55a4b69969de5Test
https://doaj.org/article/8f7e8894b23a4f8eb32f5d2c26ccefc6Test -
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المؤلفون: Tracy M. Josephs, Le Vi Dinh, Aaron DeBono, Karen J. Gregory, Ben Capuano, Katie Leach, Andrew N. Keller
المصدر: ChemMedChem. 16:3451-3462
مصطلحات موضوعية: Models, Molecular, Agonist, Cinacalcet, Allosteric modulator, medicine.drug_class, Allosteric regulation, Parathyroid hormone, Pharmacology, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Drug Discovery, medicine, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Receptor, 030304 developmental biology, 0303 health sciences, Hyperparathyroidism, Molecular Structure, business.industry, Organic Chemistry, medicine.disease, Rats, 3. Good health, Molecular Medicine, Calcium-sensing receptor, business, Receptors, Calcium-Sensing, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae6fb332a8d843eba78579a028bae17Test
https://doi.org/10.1002/cmdc.202100368Test -
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المؤلفون: Christopher S. Hofmann, Karen J. Gregory, Colleen M. Niswender, Sheridan J. S. Carrington, Andrew N. Keller
المصدر: RNA. 27:1220-1240
مصطلحات موضوعية: RNA editing, G protein, Metabotropic glutamate receptor 4, ADAR, Glutamate receptor, RNA, Biology, Heteroreceptor, Receptor, Molecular Biology, Cell biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c146cfbe89018a9aa22a22c88cd2b843Test
https://doi.org/10.1261/rna.078729.121Test -
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المؤلفون: Tracy Marie Josephs, Frankie Zhang, Le Vi Dinh, Andrew N Keller, Arthur D. Conigrave, Ben Capuano, Karen Joan Gregory, Katie Leach
المصدر: Journal of molecular endocrinology. 69(1)
مصطلحات موضوعية: Endocrinology, HEK293 Cells, Mutation, Hypercalcemia, Infant, Newborn, Humans, Calcium, Cinacalcet, Precision Medicine, Hyperparathyroidism, Primary, Molecular Biology, Receptors, Calcium-Sensing
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697b6b38d8a83940ae285af376f8ea7eTest
https://pubmed.ncbi.nlm.nih.gov/35318962Test -
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المؤلفون: Alexandra J. Corbett, Ligong Liu, Jamie Rossjohn, Weijun Xu, Jeffrey Y. W. Mak, James McCluskey, Wael Awad, Xin Yi Lim, Jérôme Le Nours, David P. Fairlie, Geraldine J. M. Ler, Andrew N. Keller, Sidonia B G Eckle
المصدر: Nature Immunology. 21:400-411
مصطلحات موضوعية: 0301 basic medicine, Cellular immunity, Receptors, Antigen, T-Cell, alpha-beta, Riboflavin, T cell, Immunology, Mucosal associated invariant T cell, Ligands, Lymphocyte Activation, Major histocompatibility complex, Mucosal-Associated Invariant T Cells, Jurkat Cells, 03 medical and health sciences, 0302 clinical medicine, Antigen, Cell Line, Tumor, medicine, Humans, Immunology and Allergy, Antigens, biology, Chemistry, Antigen processing, T-cell receptor, Cell biology, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Cell activation, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94e8dfe909998ceedf8a1bb45c258e3Test
https://doi.org/10.1038/s41590-020-0616-6Test -
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المؤلفون: Arthur D. Conigrave, Thor C. Møller, Hans Bräuner-Osborne, Andrew N. Keller, Daniela Riccardi, Katie Leach, Donald T. Ward, Enikö Kállay, Fadil M. Hannan, Rebecca S. Mason, Tracy M. Josephs, Rajesh V. Thakker
المصدر: Leach, K, Hannan, F M, Josephs, T M, Keller, A N, Møller, T C, Ward, D T, Kallay, E, Mason, R S, Thakker, R V, Riccardi, D, Conigrave, A D & Bräuner-Osborne, H 2020, ' International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function ', Pharmacological Reviews, vol. 72, no. 3, pp. 558-604 . https://doi.org/10.1124/pr.119.018531Test
Pharmacological Reviews
Pharmacol Revمصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Agonist, G protein, medicine.drug_class, Allosteric regulation, Article, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, GTP-Binding Proteins, Small Molecule Libraries/pharmacology, medicine, Functional selectivity, Animals, Humans, Receptor, Pharmacology, Binding Sites, Drug discovery, Chemistry, 3. Good health, Cell biology, 030104 developmental biology, Receptors, Calcium-Sensing/agonists, Molecular Medicine, GTP-Binding Proteins/metabolism, Signal transduction, Calcium-sensing receptor, Receptors, Calcium-Sensing, 030217 neurology & neurosurgery, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172ef793c4bcbce0c405d4a538a416f0Test
https://ora.ox.ac.uk/objects/uuid:36ba0adf-bb2b-4474-a8fa-928bf788b385Test -
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المؤلفون: Rebecca S. Mason, Irina Kufareva, Katie Leach, Hee-Chang Mun, Elham Khajehali, Karen J. Gregory, Mahvash Ayesha Goolam, Arthur D. Conigrave, Arthur Christopoulos, Ben Capuano, Andrew N. Keller
المصدر: ACS pharmacology & translational science, vol 1, iss 2
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, calhex231, Allosteric modulator, calcium-sensing receptor, Chemistry, Drug discovery, Allosteric regulation, allosteric modulator, Endogeny, 3. Good health, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 5.1 Pharmaceuticals, Dual action, Mode switching, Pharmacology (medical), Development of treatments and therapeutic interventions, Calcium-sensing receptor, Receptor, Lung, Neuroscience, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db8247e4d4b471b64944973f8e446e7Test
https://doi.org/10.1021/acsptsci.8b00021Test -
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المؤلفون: Elham Khajehali, Aaron DeBono, Christopher J. Langmead, Arthur D. Conigrave, Ben Capuano, Tracy M. Josephs, Karen J. Gregory, Katie Leach, Irina Kufareva, Andrew N. Keller
المصدر: British journal of pharmacology, vol 177, iss 8
Br J Pharmacolمصطلحات موضوعية: 0301 basic medicine, 1.1 Normal biological development and functioning, Allosteric regulation, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Underpinning research, Receptors, Humans, Pharmacology & Pharmacy, Binding site, Receptor, Pharmacology, Binding Sites, Chemistry, Mutagenesis, HEK 293 cells, Pharmacology and Pharmaceutical Sciences, Research Papers, 3. Good health, Cell biology, Transmembrane domain, 030104 developmental biology, HEK293 Cells, Parathyroid hormone secretion, Calcium-Sensing, Calcium-sensing receptor, Receptors, Calcium-Sensing, 030217 neurology & neurosurgery, Allosteric Site
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9600bc6fa0ab8e4daccda0683b1a0cTest
https://escholarship.org/uc/item/9kc638dmTest