المؤلفون: Meijboom, Katharina E, Abdallah, Abbas, Fordham, Nicholas P, Nagase, Hiroko, Rodriguez, Tomás, Kraus, Carolyn, Gendron, Tania F, Krishnan, Gopinath, Esanov, Rustam, Andrade, Nadja S, Rybin, Matthew J, Ramic, Melina, Stephens, Zachary D, Edraki, Alireza, Blackwood, Meghan T, Kahriman, Aydan, Henninger, Nils, Kocher, Jean-Pierre A, Benatar, Michael, Brodsky, Michael H, Petrucelli, Leonard, Gao, Fen-Biao, Sontheimer, Erik J, Brown, Robert H, Zeier, Zane, Mueller, Christian

المساهمون: Horae Gene Therapy Center, Molecular, Cell and Cancer Biology, Morningside Graduate School of Biomedical Sciences, Neurology, Program in Molecular Medicine, RNA Therapeutics Institute

المصدر: Nature communications ; 13 ; 1 ; 6286 ; United States ; England

مصطلحات موضوعية: Amyotrophic lateral sclerosis, CRISPR-Cas9 genome editing

العلاقة: Nature Communications; https://doi.org/10.1038/s41467-022-33332-7Test; Meijboom KE, Abdallah A, Fordham NP, Nagase H, Rodriguez T, Kraus C, Gendron TF, Krishnan G, Esanov R, Andrade NS, Rybin MJ, Ramic M, Stephens ZD, Edraki A, Blackwood MT, Kahriman A, Henninger N, Kocher JA, Benatar M, Brodsky MH, Petrucelli L, Gao FB, Sontheimer EJ, Brown RH, Zeier Z, Mueller C. CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro. Nat Commun. 2022 Oct 21;13(1):6286. doi:10.1038/s41467-022-33332-7. PMID: 36271076; PMCID: PMC9587249.; http://hdl.handle.net/20.500.14038/51610Test

الإتاحة: https://doi.org/10.1038/s41467-022-33332-7Test
https://doi.org/20.500.14038/51610Test
https://hdl.handle.net/20.500.14038/51610Test

المؤلفون: Ricciardi, Natalie R., Modarresi, Farzaneh, Lohse, Ines, Andrade, Nadja S., Newman, Ian R., Brown, Jonathan M., Borja, Caroline, Marples, Brian, Wahlestedt, Claes R., Volmar, Claude-Henry

المصدر: Molecular Neurobiology ; volume 60, issue 8, page 4811-4827 ; ISSN 0893-7648 1559-1182

مصطلحات موضوعية: Neuroscience (miscellaneous), Cellular and Molecular Neuroscience, Neurology

الإتاحة: https://doi.org/10.1007/s12035-023-03373-0Test

المؤلفون: Poukalov, Kiril K., Valero, M. Carmen, Muscato, Derek R., Adams, Leanne M., Heejae Chun, Young il Lee, Andrade, Nadja S., Zeier, Zane, Sweeney, H. Lee, Wang, Eric T.

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 5/7/2024, Vol. 121 Issue 19, p1-9, 21p

مصطلحات موضوعية: GENOME editing, SKELETAL muscle, GENE therapy, DUCHENNE muscular dystrophy, CRISPRS

المؤلفون: Esanov, Rustam, Toro Cabrera, Gabriela, Andrade, Nadja S., Gendron, Tania F., Brown, Robert H. Jr., Benatar, Michael, Wahlestedt, Claes, Mueller, Christian, Zeier, Zane

المساهمون: Department of Neurology, Horae Gene Therapy Center, Department of Pediatrics, Division of Pulmonology

المصدر: Molecular neurodegeneration ; 12 ; 1 ; 46

مصطلحات موضوعية: Amyotrophic lateral sclerosis, C9ORF72 BAC mouse DNA methylation, Hydroxymethylation, Induced pluripotent stem cells, R-loops, Genetics and Genomics, Molecular and Cellular Neuroscience, Nervous System Diseases

العلاقة: Link to Article in PubMed; Mol Neurodegener. 2017 Jun 12;12(1):46. doi:10.1186/s13024-017-0185-9. Link to article on publisher's site; 1750-1326 (Linking); http://hdl.handle.net/20.500.14038/43583Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1152&context=peds_pp&unstamped=1Test; https://escholarship.umassmed.edu/peds_pp/153Test; peds_pp/153

الإتاحة: https://doi.org/10.1186/s13024-017-0185-9Test
https://doi.org/20.500.14038/43583Test
https://hdl.handle.net/20.500.14038/43583Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1152&context=peds_pp&unstamped=1Test
https://escholarship.umassmed.edu/peds_pp/153Test

المؤلفون: Andrade, Nadja S., Abdallah, Abbas, Mueller, Christian, Zeier, Zane

المساهمون: Horae Gene Therapy Center, Department of Pediatrics, Department of Neurology

المصدر: Molecular neurodegeneration ; 15 ; 1 ; 13

مصطلحات موضوعية: Amyotrophic lateral sclerosis, CRISPR, DNA damage, DNA double strand break repair, Homology-directed repair, Induced pluripotent stem cells, RAD52, Single-strand annealing, Biochemical Phenomena, Metabolism, and Nutrition, Cell Biology, Genetics and Genomics, Molecular Biology, Nervous System, Nervous System Diseases, Neurology, Neuroscience and Neurobiology

العلاقة: Link to Article in PubMed; Andrade NS, Ramic M, Esanov R, Liu W, Rybin MJ, Gaidosh G, Abdallah A, Del'Olio S, Huff TC, Chee NT, Anatha S, Gendron TF, Wahlestedt C, Zhang Y, Benatar M, Mueller C, Zeier Z. Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD. Mol Neurodegener. 2020 Feb 24;15(1):13. doi:10.1186/s13024-020-00365-9. PMID: 32093728; PMCID: PMC7041170. Link to article on publisher's site; 1750-1326 (Linking); http://hdl.handle.net/20.500.14038/41384Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5184&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/4165Test; oapubs/4165

الإتاحة: https://doi.org/10.1186/s13024-020-00365-9Test
https://doi.org/20.500.14038/41384Test
https://hdl.handle.net/20.500.14038/41384Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5184&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/4165Test

المؤلفون: Meijboom, Katharina E., Abdallah, Abbas, Fordham, Nicholas P., Nagase, Hiroko, Rodriguez, Tomás, Kraus, Carolyn, Gendron, Tania F., Krishnan, Gopinath, Esanov, Rustam, Andrade, Nadja S., Rybin, Matthew J., Ramic, Melina, Stephens, Zachary D., Edraki, Alireza, Blackwood, Meghan T., Kahriman, Aydan, Henninger, Nils, Kocher, Jean-Pierre A., Benatar, Michael, Brodsky, Michael H., Petrucelli, Leonard, Gao, Fen-Biao, Sontheimer, Erik J., Brown, Robert H., Zeier, Zane, Mueller, Christian

المساهمون: U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

المصدر: Nature Communications ; volume 13, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-022-33332-7Test
https://www.nature.com/articles/s41467-022-33332-7.pdfTest
https://www.nature.com/articles/s41467-022-33332-7Test

المؤلفون: Johnstone, Andrea L., Andrade, Nadja S., Barbier, Estelle, Khomtchouk, Bohdan B., Rienas, Christopher A., Lowe, Kenneth, Van Booven, Derek J., Domi, Esi, 1985, Esanov, Rustam, Vilca, Samara, Tapocik, Jenica D., Rodriguez, Keli, Maryanski, Danielle, Keogh, Michael Christopher, Meinhardt, Marcus W., Sommer, Wolfgang H., Heilig, Markus, 1959, Zeier, Zane, Wahlestedt, Claes

المصدر: Addiction Biology. 26(1)

مصطلحات موضوعية: alcoholism, epigenetics, inflammation, JMJD3, KDM6B, nucleus accumbens, prefrontal cortex

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-159869Test
https://liu.diva-portal.org/smash/get/diva2:1346271/FULLTEXT01.pdfTest

المؤلفون: Andrade, Nadja S., Ramic, Melina, Esanov, Rustam, Liu, Wenjun, Rybin, Mathew J., Gaidosh, Gabriel, Abdallah, Abbas, Del’Olio, Samuel, Huff, Tyler C., Chee, Nancy T., Anatha, Sadhana, Gendron, Tania F., Wahlestedt, Claes, Zhang, Yanbin, Benatar, Michael, Mueller, Christian, Zeier, Zane

المساهمون: National Institute of Neurological Disorders and Stroke, U.S. Department of Defense, National Institutes of Health

المصدر: Molecular Neurodegeneration ; volume 15, issue 1 ; ISSN 1750-1326

مصطلحات موضوعية: Cellular and Molecular Neuroscience, Neurology (clinical), Molecular Biology

الإتاحة: https://doi.org/10.1186/s13024-020-00365-9Test

المؤلفون: Volmar, Claude‐Henry, Ricciardi, Natalie R, Modarresi, Farzaneh, Lohse, Ines, Andrade, Nadja S, Newman, Ian R, Brown, Jonathan M, Borja, Caroline, Marples, Brian, Wahlestedt, Claes

المصدر: Alzheimer's & Dementia ; volume 19, issue S21 ; ISSN 1552-5260 1552-5279

الإتاحة: https://doi.org/10.1002/alz.074900Test

المؤلفون: Johnstone, Andrea L., Andrade, Nadja S., Barbier, Estelle, Khomtchouk, Bohdan B., Rienas, Christopher A., Lowe, Kenneth, Van Booven, Derek J., Domi, Esi, Esanov, Rustam, Vilca, Samara, Tapocik, Jenica D., Rodriguez, Keli, Maryanski, Danielle, Keogh, Michael Christopher, Meinhardt, Marcus W., Sommer, Wolfgang H., Heilig, Markus, Zeier, Zane, Wahlestedt, Claes

المساهمون: National Institute of Mental Health, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, U.S. Department of Defense

المصدر: Addiction Biology ; volume 26, issue 1 ; ISSN 1355-6215 1369-1600

الإتاحة: https://doi.org/10.1111/adb.12816Test