المؤلفون: Miho Waga, Akihiko Nakano, Auxiliadora Aguilera-Romero, Alejandro Cortes-Gomez, Sergio López, Sofia Rodriguez-Gallardo, Manuel Muñiz, Kazuo Kurokawa, Susana Sabido-Bozo, Ana Maria Perez-Linero

المساهمون: [Rodriguez-Gallardo,S, Sabido-Bozo,S, Cortes-Gomez,A, Perez-Linero,AM, Aguilera-Romero,A, Lopez,S, Muñiz,M] Department of Cell Biology, University of Seville and Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain. [Kurokawa,K, Waga,M, Nakano,A] Live Cell Super-Resolution Imaging Research Team, RIKEN Center for Advanced Photonics, Saitama, Japan., MM, BFU2017-89700-P, FEDER/Ministerio de Ciencia, Innovación y Universidades-Agencia Estatal de Investigación, https://www.ciencia.gob.es/portal/site/MICINN/aeiTest AN and KK, JP25221103, JP17H06420 and JP18H05275, Japan Society for the Promotion of Science (JSPS), https://www.jsps.go.jp/english/index.htmlTest, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Japan Society for the Promotion of Science, Universidad de Sevilla. Departamento de Biología Celular

المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258111 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC

مصطلحات موضوعية: Fluorescence-lifetime imaging microscopy, Cell Membranes, Golgi Apparatus, Endoplasmic Reticulum, Biochemistry, Anatomy::Cells::Cellular Structures::Cell Membrane::Intracellular Membranes [Medical Subject Headings], Ceramide, Fluorescence Microscopy, Lab Protocol, Cargo Proteins, Microscopía, Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum [Medical Subject Headings], ERES, COPII, Microscopy, Multidisciplinary, Secretory Pathway, Microscopy, Confocal, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Imaging, Three-Dimensional [Medical Subject Headings], Chemistry, Phenomena and Processes::Metabolic Phenomena::Metabolism::Biological Transport::Protein Transport [Medical Subject Headings], Membrane, Eukaryota, Light Microscopy, ER retention, Lipids, Cell biology, Protein Transport, Cell Processes, symbols, Medicine, Phenomena and Processes::Metabolic Phenomena::Metabolism::Biological Transport [Medical Subject Headings], Cellular Structures and Organelles, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Microscopy::Microscopy, Confocal [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Golgi Apparatus [Medical Subject Headings], Imaging Techniques, Science, Research and Analysis Methods, Retículo endoplásmico, symbols.namesake, Imaging, Three-Dimensional, Live cell imaging, Fluorescence Imaging, Secretory pathway, Endoplasmic reticulum, Protein, Organisms, Fungi, Biology and Life Sciences, Proteins, Membrane Proteins, Biological Transport, Cell Biology, Intracellular Membranes, Golgi apparatus, Yeast, Membranas, Ceramidas, Secretory protein, Proteína

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59320712b058d18e251534ae6e08dd3Test
https://hdl.handle.net/10668/3822Test

المؤلفون: Kouichi Funato, Manuel Muñiz, Miyako Nakano, Kouta Okazaki, Atsuko Ikeda, Alejandro Cortes-Gomez, Auxiliadora Aguilera-Romero, Susana Sabido-Bozo, Sofia Rodriguez-Gallardo, Sergio López

المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Japan Society for the Promotion of Science, [Nakano,M, Okazaki,K, Ikeda,A, Funato,K] Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan. [Sabido-Bozo,S, Aguilera-Romero,A, Rodriguez-Gallardo,S, Cortes-Gomez,A, Lopez,S, Muñiz,M] Facultad de Biologia, Departamento de Biologia Celular, Hospital Universitario Virgen del Rocio/CSIC/Universidad de Sevilla, Universidad de Sevilla e Instituto de Biomedicina de Sevilla (IBiS), Sevilla, Spain., MM. BFU2017-89700-P. FEDER/Ministerio de Ciencia, Innovación y Universidades—Agencia Estatal de Investigación. http://www.aei.gob.esTest/. MN and KF. JP19H02922. Japan Society for the Promotion of Science. https://www.jsps.go.jp/englishTest/. The funders had and will not have a role in study design, data collection and analysis, decision to publish, or preparation of the manuscript., Universidad de Sevilla. Departamento de Biología Celular, Ministerio de Ciencia, Innovación y Universidades (MICINN). España, European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER)

المصدر: PLoS ONE, Vol 16, Iss 9, p e0257435 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC

مصطلحات موضوعية: Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::GPI-Linked Proteins [Medical Subject Headings], Cell Membranes, Cell, Electrophoretic techniques, Endoplasmic Reticulum, Biochemistry, Phenomena and Processes::Digestive System and Oral Physiological Phenomena::Digestive System Physiological Phenomena::Digestive System Processes::Digestion [Medical Subject Headings], Green fluorescent protein, Lab Protocol, Tandem Mass Spectrometry, Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum [Medical Subject Headings], Trypsin, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Electrophoresis [Medical Subject Headings], Organisms::Eukaryota::Fungi::Ascomycota::Saccharomycetales::Saccharomyces::Saccharomyces cerevisiae [Medical Subject Headings], Staining, Secretory Pathway, Multidisciplinary, biology, Chemistry, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Protein Modification, Translational::Protein Processing, Post-Translational [Medical Subject Headings], Eukaryota, Proteases, Specimen preparation and treatment, Enzyme structure, Precipitation Techniques, Enzymes, Cell biology, medicine.anatomical_structure, Chemicals and Drugs::Carbohydrates::Glycoconjugates::Glycolipids::Glycosylphosphatidylinositols [Medical Subject Headings], Cell Processes, Digestión, Medicine, Digestion, lipids (amino acids, peptides, and proteins), Cellular Structures and Organelles, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry::Tandem Mass Spectrometry [Medical Subject Headings], Electrophoresis, Glycan, Immunoprecipitation, Science, Saccharomyces cerevisiae, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Endopeptidases::Serine Endopeptidases::Trypsin [Medical Subject Headings], Research and Analysis Methods, GPI-Linked Proteins, Retículo endoplásmico, Coomassie Blue staining, Polysaccharides, medicine, Electroforesis, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Biosynthetic Pathways [Medical Subject Headings], Mass spectrometry, Endoplasmic reticulum, Glicosilfosfatidilinositoles, Organisms, Fungi, Biology and Life Sciences, Membrane Proteins, Proteins, Péptidos, Cell Biology, Gel electrophoresis, Yeast, Tripsina, carbohydrates (lipids), Glycosylphosphatidylinositol, Membrane protein, Electrophoretic staining, Enzyme Structure, Enzymology, biology.protein, Espectrometría de masas, Serine Proteases, Peptides, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry [Medical Subject Headings]

وصف الملف: application/pdf; image/tiff

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5c1065017d1909699c37b92d2a8e02Test
http://hdl.handle.net/10261/261951Test

المؤلفون: Villanueva-Paz, Marina, Morán, Laura, López-Alcántara, Nuria, Freixo, Cristiana, Andrade, Raúl J., Lucena, M Isabel, Cubero, Francisco Javier

المساهمون: [Villanueva-Paz,M, Andrade,RJ, Lucena,MI] Unidad de Gestión Clínica de Gastroenterología, Servicio de Farmacología Clínica, Instituto de Investigación Biomédica de Málaga-IBIMA, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, CIBERehd, Málaga, Spain. [Morán,L, López-Alcántara,N, Cubero,FJ] Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine, Madrid, Spain. [Morán,L] Health Research Institute Gregorio Marañón (IiSGM), Madrid, Spain. [Freixo,C] CINTESIS, Center for Health Technology and Services Research, do Porto University School of Medicine, Porto, Portugal. [Cubero,FJ] 12 de Octubre Health Research Institute (imas12), Madrid, Spain., This work was supported by the MINECO Retos SAF2016-78711, EXOHEP-CM S2017/BMD-3727, NanoLiver-CM Y2018/NMT-4949, ERAB Ref. EA 18/14, AMMF 2018/117, FIS-FEDER PI16_01748, PI19-00883, UMA18-FEDERJA-194, PY18-3364_PY19 and UCM-25-2019. FJC is a Ramón y Cajal Researcher RYC-2014-15242 and a Gilead Liver Research 2018. The research group belongs to the validated Research Groups Ref. 970935 'Liver Pathophysiology' and 920631 'Lymphocyte immunobiology' and IBL-6 (imas12-associated). This article/publication is based upon work from COST Action 'CA17112—Prospective European Drug-Induced Liver Injury Network' supported by COST (European Cooperation in Science and Technology), accessed 4 March 2021. CIBERehd is funded by ISCiii.

مصطلحات موضوعية: Diseases::Digestive System Diseases::Liver Diseases::Hepatic Insufficiency::Liver Failure::Liver Failure, Acute [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum [Medical Subject Headings], Mechanisms, Chemicals and Drugs::Biological Factors::Biological Markers [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Acid Anhydride Hydrolases::GTP Phosphohydrolases::GTP-Binding Proteins [Medical Subject Headings], Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria [Medical Subject Headings], Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Laboratories [Medical Subject Headings], Phenomena and Processes::Immune System Phenomena::Immunity::Adaptive Immunity [Medical Subject Headings], Estrés oxidativo, Anatomy::Cells::Epithelial Cells::Hepatocytes [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Noxae::Oxidants [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Superoxide Dismutase [Medical Subject Headings], Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Oligopeptides::Glutathione [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Antisense Elements (Genetics)::RNA, Antisense::MicroRNAs [Medical Subject Headings], Biomarcadores, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Glutathione Peroxidase [Medical Subject Headings], Risk factors, Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes::Inflammasomes [Medical Subject Headings], Oxidative stress, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Catalase [Medical Subject Headings], DILI, Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Histocompatibility Antigens::HLA Antigens [Medical Subject Headings], Biomarkers, Factores de riesgo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______2636::bdd9638b821bda900adbd7cfa53d20f9Test
https://hdl.handle.net/10668/3663Test

المؤلفون: Miguel Navarro-Alarcón, Lazhar Zourgui, Ahmad Agil, Marwa Ncir, Pablo Alarcón-Guijo, Diego Salagre, Samira Aouichat

المساهمون: [Aouichat.S, Alarcón-Guijo,P, Salagre.D, Agil,A] Department of Pharmacology, Biohealth Institute and Neurosciences Institute, School of Medicine, University of Granada, Granada, Spain. [Aouichat.S] Team of Cellular and Molecular Physiopathology, Faculty of Biological Sciences, University of Sciences and Technology Houari Boumediene, El Alia, Algiers, Algeria. [Navarro-Alarcon,M] Department of Nutrition and Bromatology, School of Pharmacy, University of Granada, Granada, Spain. [Ncir.M, Zourgui,L] Bioactive Molecule Valorization Research Unit, Higher Institute of Applied Biology of Medenine, University of Gabes, Gabes, Tunisia. [Agil,A] Biosanitary Research Institute of Granada (ibs. GRANADA), University Hospital of Granada, Granada, Spain., This work was supported by grant SAF2016-79794-R from the Ministerio de Ciencia e Innovación (Spain) and European Regional Development Fund (ERDF).

المصدر: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Pharmaceuticals, Vol 14, Iss 232, p 232 (2021)
Pharmaceuticals
Volume 14
Issue 3
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

مصطلحات موضوعية: 0301 basic medicine, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases [Medical Subject Headings], Anatomy::Urogenital System::Urinary Tract::Kidney [Medical Subject Headings], Obesidad, lcsh:Medicine, lcsh:RS1-441, Pharmaceutical Science, Estrés del retículo endoplásmico, Riñón, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cysteine Proteases::Cysteine Endopeptidases::Caspases::Caspases, Effector::Caspase 3 [Medical Subject Headings], melatonin, Kidney, Melatonina, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Proto-Oncogene Proteins c-bcl-2::bcl-2-Associated X Protein [Medical Subject Headings], 0302 clinical medicine, Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum [Medical Subject Headings], Drug Discovery, Organisms::Eukaryota::Animals [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence [Medical Subject Headings], Melatonin, Chemistry, Kinase, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Molecular Probe Techniques::Blotting, Western [Medical Subject Headings], Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases [Medical Subject Headings], Diabesity, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Mitogen-Activated Protein Kinases::JNK Mitogen-Activated Protein Kinases [Medical Subject Headings], medicine.anatomical_structure, Caspase-3, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Mitochondrial Turnover::Mitochondrial Dynamics [Medical Subject Headings], Technology and Food and Beverages::Food and Beverages::Food::Dietary Supplements [Medical Subject Headings], endoplasmic reticulum stress, Endoplasmic reticulum stress, Molecular Medicine, Mitochondrial fission, medicine.drug, kidney, medicine.medical_specialty, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction::MAP Kinase Signaling System [Medical Subject Headings], Article, lcsh:Pharmacy and materia medica, 03 medical and health sciences, Diseases::Neoplasms::Neoplasms by Histologic Type::Lymphoma::Lymphoma, Non-Hodgkin::Lymphoma, B-Cell [Medical Subject Headings], Downregulation and upregulation, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Peptide Biosynthesis::Protein Biosynthesis::Protein Modification, Translational::Protein Processing, Post-Translational::Unfolded Protein Response [Medical Subject Headings], Internal medicine, medicine, Caspasa 3, Obesity, Proteínas quinasas JNK activadas por mitógenos, Phenomena and Processes::Cell Physiological Phenomena::Endoplasmic Reticulum Stress [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation [Medical Subject Headings], Diseases::Endocrine System Diseases::Diabetes Mellitus [Medical Subject Headings], ATF6, Endoplasmic reticulum, lcsh:R, JNK Mitogen-Activated Protein Kinases, Kidneys, Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Indoles::Tryptamines::Melatonin [Medical Subject Headings], B cell lymphoma, Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings], 030104 developmental biology, Endocrinology, Linfoma de células B, diabesity, Unfolded protein response, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f5d2a183f2f853b3a7a5364448919eTest

المؤلفون: Stefano Vanni, Miyako Nakano, Misako Araki, Alejandro Cortes-Gomez, Sofia Rodriguez-Gallardo, Auxiliadora Aguilera-Romero, Valeria Zoni, Atsuko Ikeda, Sergio López, Susana Sabido-Bozo, Howard Riezman, Kazuo Kurokawa, Manuel Muñiz, Miho Waga, Kouichi Funato, Akihiko Nakano, Ana Maria Perez-Linero

المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Universidad de Sevilla, Japan Society for the Promotion of Science, Swiss National Science Foundation, Swiss National Supercomputing Centre, National Centres of Competence in Research (Switzerland), Ministerio de Educación, Cultura y Deporte (España), [Rodriguez-Gallardo,S, Sabido-Bozo,S, Cortes-Gomez,A, Aguilera-Romero,A, Perez-Linero,AM, Lopez,S, Muñiz,M] Department of Cell Biology, Faculty of Biology, University of Seville and Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain. [Kurokawa,K, Waga,M, Nakano,A] Live Cell Super-Resolution Imaging Research Team, RIKEN Center for Advanced Photonics, Saitama, Japan. [Zoni,V, Vanni, S] Department of Biology, University of Fribourg, Fribourg, Switzerland. [Ikeda,A, Araki,M, Nakano,M, Funato,K] Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, Japan. [Riezman,H] NCCR Chemical Biology, Department of Biochemistry, University of Geneva, Geneva, Switzerland., This research was funded by the Spanish Ministry of Economy and Competitiveness (MINECO, grant number BFU2017-89700-P to M.M.), 'VI Own Research Plan' of the University of Seville (VIPPIT-2020-I.5 to M.M.), and Grants-in-Aid for Scientific Research from Japan Society for the Promotion of Science (JP25221103, JP17H06420, and JP18H05275 to A.N. and K. K., and JP19H02922 to M.N. and K.F.). S.V. and V.Z. acknowledge support from the Swiss National Science Foundation (grant no. 163966) and from the Swiss National Supercomputing Centre (CSCS) under project IDs s726 and s842. H.R. is supported by the Swiss National Science Foundation and the NCCR Chemical Biology (grants 184949 and 185898). This research was funded by the 'VI Own Research Plan 'of the University of Seville (VIPPIT-2020-I.5), 'V Own Research Plan' of the University of Seville (VPPI-US) contract (cofounded by the European Social Fund) to S.L., University of Seville fellowship to S.R.-G., Ministry of Education, Culture, and Sport (MECD) fellowship to S.S.-B., and contract from the University of Seville by the Youth Employment Initiative to A.C.-G., Universidad de Sevilla. Departamento de Biología Celular, Ministerio de Economía y Competitividad (MINECO). España, Swiss National Science Foundation (SNFS), Swiss National Supercomputing Centre (CSCS)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Fundacion Sancho el Sabio Fundazioa (FSS)
Science Advances

مصطلحات موضوعية: Vías secretorias, Endoplasmic Reticulum, medicine.disease_cause, Biochemistry, Chemicals and Drugs::Organic Chemicals::Amides::Ceramides [Medical Subject Headings], chemistry.chemical_compound, 0302 clinical medicine, Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum [Medical Subject Headings], Protein targeting, Research Articles, 0303 health sciences, Secretory Pathway, Multidisciplinary, Phenomena and Processes::Metabolic Phenomena::Metabolism::Biological Transport::Protein Transport [Medical Subject Headings], Chemistry, SciAdv r-articles, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins [Medical Subject Headings], Compartmentalization (psychology), Lipids, Anatomy::Tissues::Membranes [Medical Subject Headings], Transmembrane protein, Cell biology, Protein Transport, Lípidos, Proteínas, Reticulum, Research Article, Anatomy::Animal Structures::Stomach, Ruminant::Reticulum [Medical Subject Headings], Ceramide, Cell signaling, Chemicals and Drugs::Lipids [Medical Subject Headings], Ceramides, Retículo endoplásmico, Chemicals and Drugs::Lipids::Glycolipids::Glycosylphosphatidylinositols [Medical Subject Headings], 03 medical and health sciences, Live cell imaging, medicine, Secretory pathway, 030304 developmental biology, Membranes, Endoplasmic reticulum, Glicosilfosfatidilinositoles, Proteins, Membrane Proteins, Membranas, Ceramidas, Glycosylphosphatidylinositol, Phenomena and Processes::Metabolic Phenomena::Metabolism::Biological Transport::Secretory Pathway [Medical Subject Headings], Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis [Medical Subject Headings], 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a1b0089882cfe7683dbc4bdb32bbc7Test
http://hdl.handle.net/10261/237777Test

المؤلفون: Joan Vendrell, Elsa Maymó-Masip, Matilde R. Chacón, Ana Megia, Francisco J. Tinahones, Antonio Garcia-España, Enric Caubet, Eduardo García-Fuentes

المساهمون: [Vendrell,J, Maymó-Masip,E, Megía,A, Chacón,MR] Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas, Hospital Universitari de Tarragona Joan XXIII, Spain. [Vendrell,J, Chacón,MR, García-España,A] IISPV (Institut d’Investigació Sanitaria 'Pere Virgili'), Universitat Rovira i Virgili, Tarragona, Spain. [Tinahones Madueño,FJ, García-Fuentes,E] Centro de Investigación Biomédica en Red de Fisiopatología, Obesidad y Nutrición, Department of Obesity and Nutrition, Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Caubet,E] Department of Surgery, Hospital St. Pau i Sta Tecla, Tarragona, Spain., This work was supported by Grants from Fondo de Investigacion Sanitaria PI 08/0733 and CP06/00119 cofinanced by the European Regional Development Fund. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas de Diabetes y Enfermedades Metabólicas Asociadas (CB07/08/ 0012) is an initiative of the Instituto de Salud Carlos III (ISCIII).A.G.-E. is supported by the Research Stabilization Program of the ISCIII-Institut Català de Salut in Catalonia. M.R.C. is supported by a fellowship from the Fondo de Investigación Sanitaria (CP06/00119).

مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biopsy, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Tumor Necrosis Factors [Medical Subject Headings], Clinical Biochemistry, Gene Expression, Adipose tissue, Type 2 diabetes, Diabetes Mellitus Tipo 2, Endoplasmic Reticulum, Biochemistry, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression [Medical Subject Headings], Receptors, Tumor Necrosis Factor, Cohort Studies, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], chemistry.chemical_compound, Endocrinology, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Surgical::Biopsy [Medical Subject Headings], Anoxia, Anatomy::Cells::Cells, Cultured::Cell Line [Medical Subject Headings], Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum [Medical Subject Headings], Adipocyte, Adipocytes, Tejido Adiposo, Hypoxia, Endoplasmic Reticulum Chaperone BiP, Cytokine TWEAK, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Cytokine::Receptors, Tumor Necrosis Factor [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction [Medical Subject Headings], Citocinas, General Medicine, TNFSF12 protein, human, TWEAK receptor, Anatomy::Tissues::Connective Tissue::Adipose Tissue [Medical Subject Headings], Obesity, Morbid, Up-Regulation, Cytokine, Adipose Tissue, TWEAK Receptor, Anatomy::Cells::Connective Tissue Cells::Adipocytes [Medical Subject Headings], Tumor Necrosis Factors, Cytokines, Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2 [Medical Subject Headings], Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid [Medical Subject Headings], Tumor necrosis factor alpha, medicine.symptom, Signal Transduction, medicine.medical_specialty, Western Blotting, Línea Celular, Obesidad Mórbida, Expresión Génica, Blotting, Western, Inflammation, Context (language use), Biology, Cell Line, Proinflammatory cytokine, Translational Highlights from Jcem, Internal medicine, Anatomy::Cells::Connective Tissue Cells::Macrophages [Medical Subject Headings], Adipocitos, medicine, Humans, Macrófagos, Molecular Biology, Regulación hacia Arriba, Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Signs and Symptoms, Respiratory::Anoxia [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines [Medical Subject Headings], Inflamación, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation [Medical Subject Headings], Factores de Necrosis Tumoral, Macrophages, Biochemistry (medical), Transducción de Señal, Hypoxia (medical), medicine.disease, Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings], Biopsia, Diabetes Mellitus, Type 2, chemistry, Immunology, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Electrophoresis::Blotting, Western [Medical Subject Headings], Tumor Necrosis Factor Inhibitors, Retículo Endoplásmico, Receptores del Factor de Necrosis Tumoral, Estudios de Cohortes, Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation [Medical Subject Headings]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6134d68e0308c3e598d458456341c604Test
https://hdl.handle.net/10668/750Test

المؤلفون: Francisco Gracia-Navarro, Gema Frühbeck, Yolanda Jimenez-Gomez, Francisco J. Tinahones, María M. Malagón, Alberto Diaz-Ruiz, Socorro García-Navarro, Marina R. Pulido, Jose Lopez-Miranda, Rafael Vázquez-Martínez

المساهمون: [Pulido,MR, Díaz-Ruiz,A, Jiménez-Gómez,Y, García-Navarro,S, Gracia-Navarro,F, Vázquez-Martínez,R, Malagón,MM] Department of Cell Biology, Physiology and Immunology, University of Córdoba, Córdoba, Spain. [Pulido,MR, Tinahones,F, López-Miranda,J, Frühbeck,G, Malagón,MM] Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición, Córdoba, Spain. [Pulido,MR, Malagón,MM] Instituto Maimónides de Investigación Biomédica (IMIBIC), Córdoba, Spain. [Tinahones,J] Servicio de Endocrinología y Nutrición, Hospital Clínico Virgen de la Victoria, Málaga, Spain. [López-Miranda,J] Lipids and Atherosclerosis Unit, Hospital Universitario Reina Sofía, Córdoba, Spain. [Frühbeck,G] Metabolic Research Laboratory, University of Navarra, Pamplona, Spain., This work has been supported by Ministerio de Ciencia e Innovación (MICINN)/FEDER (BFU2007-60180, BFU2010-17116, AGL2009-12270, FPU AP2005-3348, FPI BES-2005-7405, and Acción Integrada HF2007-0002), Junta de Andalucía (BIO-139, CTS-03039), and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Spain.

المصدر: PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e22931 (2011)
PLoS ONE 6 (7) (2011)
Helvia. Repositorio Institucional de la Universidad de Córdoba
instname

مصطلحات موضوعية: Male, Obesidad, Biochemistry, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Immunoenzyme Techniques, Mice, Endocrinology, Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism [Medical Subject Headings], Insulin Signaling Cascade, Hipoglucemiantes, Adipocyte, Organisms::Eukaryota::Animals [Medical Subject Headings], Insulin, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Acid Anhydride Hydrolases::GTP Phosphohydrolases::GTP-Binding Proteins [Medical Subject Headings], lcsh:Science, Cells, Cultured, Lipids, Cellular Structures, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction::Reverse Transcriptase Polymerase Chain Reaction [Medical Subject Headings], Medicine, Adiponectin, Adiponectina, Cell Physiology, medicine.medical_specialty, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Adipokines::Adiponectin [Medical Subject Headings], Lipolysis, Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipogenesis [Medical Subject Headings], Blotting, Western, Check Tags::Male [Medical Subject Headings], Endocrine System, Humans, RNA, Messenger, Biology, Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Insulins [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Endoplasmic reticulum, lcsh:R, Metabolismo de los Lípidos, Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger [Medical Subject Headings], Lipid droplets, Lipid Metabolism, Hormones, Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings], Reacción en Cadena de la Polimerasa de Transcriptasa Inversa, Check Tags::Female [Medical Subject Headings], chemistry, rab GTP-Binding Proteins, Anatomy::Cells::Cells, Cultured [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents [Medical Subject Headings], lcsh:Q, Anatomy and Physiology, lcsh:Medicine, Adipose tissue, Endoplasmic Reticulum, Fats, chemistry.chemical_compound, Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum [Medical Subject Headings], Insulina, Lipid droplet, Molecular Cell Biology, Adipocytes, Multidisciplinary, Reverse Transcriptase Polymerase Chain Reaction, Signaling Cascades, Células Cultivadas, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunoassay::Immunoenzyme Techniques [Medical Subject Headings], Adipogenesis, Anatomy::Cells::Connective Tissue Cells::Adipocytes [Medical Subject Headings], Lipogenesis, Células 3T3-L1, Female, Research Article, Signal Transduction, Técnicas para Inmunoenzimas, Western Blotting, Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipolysis [Medical Subject Headings], 3T3-L1 Cells, Internal medicine, Adipocitos, medicine, Animals, Hypoglycemic Agents, Obesity, Nutrition, Diabetic Endocrinology, Endocrine Physiology, Anatomy::Cells::Cells, Cultured::Cell Line::3T3 Cells [Medical Subject Headings], Lipid metabolism, Diabetes Mellitus Type 2, Subcellular Organelles, Rab 18, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Electrophoresis::Blotting, Western [Medical Subject Headings], Rab18 protein, mouse, Retículo Endoplásmico

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الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97545b3b7c2994c48a93c892b628fd2Test
https://doi.org/10.1371/journal.pone.0022931Test