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1دورية أكاديمية
المؤلفون: Melanie Berry, Amy Gustafson, Maya Wai, Alex J. Luli
المصدر: INNOVATIONS in Pharmacy, Vol 12, Iss 2 (2021)
مصطلحات موضوعية: Pharmacists, Referral and Consultation, Electronic Health Records, Humans, Community Pharmacy Services/organization & administration, Outpatients, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
العلاقة: https://pubs.lib.umn.edu/index.php/innovations/article/view/3238Test; https://doaj.org/toc/2155-0417Test
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2دورية أكاديمية
المؤلفون: Christian Nilewski, Sharada Labadie, Binqing Wei, Sushant Malhotra, Steven Do, Lewis Gazzard, Li Liu, Cheng Shao, Jeremy Murray, Yevgeniy Izrayelit, Amy Gustafson, Nicholas F. Endres, Fang Ma, Xin Ye, Jun Zou, Marie Evangelista
مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, targeting certain p, switch ii pocket, loop mutant proteins, identified decades ago, gdp state via, clinically validated strategy, selective reversible inhibitors, particular kras g12c, kras mutant proteins, d13 side chain, d13 residue relative, wt kras, kras g13d, kras <, selective inhibition, target selectively, subnanomolar binding, solvent exposure, salt bridge, recent progress, ongoing challenge, conformational flexibility
الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00478.s001Test
https://figshare.com/articles/journal_contribution/Structure-Based_Design_and_Evaluation_of_Reversible_KRAS_G13D_Inhibitors/24755604Test -
3دورية أكاديمية
المؤلفون: Ke Sherry Li (3113457), John G. Quinn (5348849), Matthew J. Saabye (11914533), Jesus F. Salcido Guerrero (11914536), Jim Nonomiya (1551319), Qihui Lian (11914539), Wilson Phung (6079235), Yevgeniy Izrayelit (276259), Benjamin T. Walters (2370577), Amy Gustafson (1503166), Nicholas F. Endres (2946417), Maureen H. Beresini (1443865), Melinda M. Mulvihill (1319328)
مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, several drugs designed, rapid ms analysis, providing tremendous flexibility, order rate constant, intact protein ms, intact protein analysis, bimolecular reaction model, automated sample preparation, 3 × 10, rapid kinetic analysis, studying covalent inhibitors, characterize covalent inhibitors, g12c sup, 5 sup, throughput kinetic characterization, irreversible covalent inhibitors, kinetic characterization, covalent inhibitors, irreversible inhibitors, covalent inhibition, k <
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المؤلفون: Ke Sherry Li, John G. Quinn, Matthew J. Saabye, Jesus F. Salcido Guerrero, Jim Nonomiya, Qihui Lian, Wilson Phung, Yevgeniy Izrayelit, Benjamin T. Walters, Amy Gustafson, Nicholas F. Endres, Maureen H. Beresini, Melinda M. Mulvihill
المصدر: Analytical Chemistry. 94:1230-1239
مصطلحات موضوعية: Analytical Chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::29bfe968fd4881356fdca488b3f19009Test
https://doi.org/10.1021/acs.analchem.1c04463Test -
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المؤلفون: Wen Liu, Amy Gustafson, Firoz Jaipuri, Erica VanderPorten, Leanne Goon, Yamin Zhang, Guosheng Wu, Zuhui Zhang, Antonio G. DiPasquale, Xiaokai Li, Angela J. Oh, Lewis J. Gazzard, Seth F. Harris, Jesse Waldo, Roheeth Kumar Pavana, Yichin Liu, Venkata Velvadapu, Cheng Shao, Yuen Po-Wai, Mario R. Mautino, Zhonghua Pei, Hank La, Hima Potturi, Georgette Castanedo, Benjamin D. Sellers, Kevin DeMent, Sanjeev Kumar, Richard Pastor, Rohan Mendonca, Brendan T. Parr
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Kynurenine pathway, biology, CYP3A4, 010405 organic chemistry, Organic Chemistry, Cytochrome P450, Oxidoreductase inhibitor, 01 natural sciences, Biochemistry, Small molecule, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, biology.protein, Indoleamine 2,3-dioxygenase, Heme
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701dd22f186bad66eefde1770830d8d6Test
https://doi.org/10.1021/acsmedchemlett.0c00004Test -
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المؤلفون: Alex J. Luli, Amy Gustafson, Melanie Berry, Maya Wai
المصدر: Innovations in Pharmacy
INNOVATIONS in Pharmacy, Vol 12, Iss 2 (2021)مصطلحات موضوعية: health care facilities, manpower, and services, education, Community Pharmacy Services/organization & administration, Pharmacist, Pharmacy, Pharmacists, Type of service, Pharmacy and materia medica, health services administration, Outpatients, medicine, Electronic Health Records, Humans, Duration (project management), Pharmacists, Referral and Consultation, Electronic Health Records, Humans, Community Pharmacy Services/organization & administration, Outpatients, Referral and Consultation, health care economics and organizations, Original Research, Polypharmacy, Service (business), Descriptive statistics, business.industry, Electronic medical record, Pharmacy Practice & Practice-Based Research, medicine.disease, RS1-441, Medical emergency, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e5668dedd05c54f1972fe997798133Test
https://doi.org/10.24926/iip.v12i2.3238Test -
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المؤلفون: Yichin Liu, Peter S. Dragovich, Daniel F. Ortwine, Birong Zhang, Richard D. Cummings, Jun Liang, Yingqing Ran, Marie Classon, Sharada Labadie, Tommy Lai, Weifeng Mao, Victor S. Gehling, Bianca M. Liederer, Erica Van der Porten, Jean-Christophe Harmange, Till Mauer, Le An, Xiaoping Zheng, Jiangpeng Liao, James R. Kiefer, Maia Vinogradova, Snahel Patel, Patrick Trojer, Gauri Deshmukh, Amy Gustafson, Lesley J. Murray
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:2974-2981
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Cmax, Administration, Oral, Biological Availability, Pharmaceutical Science, Plasma protein binding, Pharmacology, Pyrazole, 01 natural sciences, Biochemistry, Pyrrolidine, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Humans, Potency, Enzyme Inhibitors, Molecular Biology, Cell potency, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, High-Throughput Screening Assays, Rats, 0104 chemical sciences, Molecular Docking Simulation, 030104 developmental biology, Lipophilicity, Microsomes, Liver, Pyrazoles, Molecular Medicine, Retinoblastoma-Binding Protein 2
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55347996293ce1a7c7b826ca989d0efTest
https://doi.org/10.1016/j.bmcl.2017.05.016Test -
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المؤلفون: Yichin Liu, Xiaoping Zheng, Lesley J. Murray, Marie Classon, Birong Zhang, Erica Van der Porten, Amy Gustafson, Jiangpeng Liao, Maia Vinogradova, Jean-Christophe Harmange, Weifeng Mao, Bianca M. Liederer, Tommy Lai, Sharada Labadie, Patrick Trojer, Richard D. Cummings, Victor S. Gehling, Gauri Deshmukh, James R. Kiefer, Peter S. Dragovich, Daniel F. Ortwine, Jun Liang
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:4036-4041
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Cell, Cmax, Administration, Oral, Pharmaceutical Science, Pyrimidinones, Molecular Dynamics Simulation, Pharmacology, Crystallography, X-Ray, Biochemistry, Histones, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Binding site, Molecular Biology, EC50, Binding Sites, Chemistry, Organic Chemistry, Rats, Bioavailability, 030104 developmental biology, medicine.anatomical_structure, Liver, 030220 oncology & carcinogenesis, Microsomes, Liver, Pyrazoles, Molecular Medicine, Female, Retinoblastoma-Binding Protein 2, Half-Life
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca2fc00b367f08650c72962e0d79153Test
https://doi.org/10.1016/j.bmcl.2016.06.078Test -
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المؤلفون: Dhireshan Gadiagellan, Amy Gustafson, Daniel P. Gross, Timothy D. Dawes, Till Maurer, Peter Thana, Linda Orren, Rebecca Turincio, Richard A. Rodriguez, Marya Liimatta, Maureen Beresini, Steven W. Jones, Kevin R Clark
المصدر: SLAS Technology. 21:64-75
مصطلحات موضوعية: Engineering, High-throughput screening, media_common.quotation_subject, Biomedical Technology, Drug Evaluation, Preclinical, 01 natural sciences, Small Molecule Libraries, Disk formatting, Transfer (computing), Quality (business), Instrumentation (computer programming), Process engineering, Acoustic droplet ejection, Simulation, media_common, business.industry, 010401 analytical chemistry, Acoustics, High-Throughput Screening Assays, 0104 chemical sciences, Computer Science Applications, Solutions, 010404 medicinal & biomolecular chemistry, Medical Laboratory Technology, Data Interpretation, Statistical, Custom software, business, Software, Primary screening
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d658af8557ba7ebd5063d796846694daTest
https://doi.org/10.1177/2211068215590588Test -
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المؤلفون: Fabien Vincent, Michelle Dourado, Daniel Emerling, Luna Liu, Victor Yip, Margaret Nguyen, Zhi-Liang Wei, Zipfel Sheila, Candace Chi, Amy Gustafson, Jeff DeFalco, Michael G. Kelly, John Kincaid, Qingling Zhang, Donogh J R O'Mahony, Matthew A.J. Duncton, Alejandra Acevedo
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:4011-4015
مصطلحات موضوعية: TRPV4, TRPV3, Stereochemistry, Clinical Biochemistry, TRPV1, Administration, Oral, Biological Availability, TRPV Cation Channels, Pharmaceutical Science, Pharmacology, Biochemistry, Piperazines, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, TRPM8, Animals, Humans, Rats, Wistar, Receptor, Molecular Biology, Ion channel, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Rats, Bioavailability, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53256b218e4196c4d5f87c151a03f04Test
https://doi.org/10.1016/j.bmcl.2015.06.098Test