المؤلفون: Ghatak, Swagata, Dolatabadi, Nima, Gao, Richard, Wu, Yin, Scott, Henry, Trudler, Dorit, Sultan, Abdullah, Ambasudhan, Rajesh, Nakamura, Tomohiro, Masliah, Eliezer, Talantova, Maria, Voytek, Bradley, Lipton, Stuart A

المصدر: Molecular Psychiatry. 26(10)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Dementia, Alzheimer's Disease, Brain Disorders, Aging, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Stem Cell Research, Stem Cell Research - Induced Pluripotent Stem Cell, Neurodegenerative, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Aetiology, Neurological, Action Potentials, Alzheimer Disease, Animals, Disease Models, Animal, Induced Pluripotent Stem Cells, Mice, Neural Networks, Computer, Neurons, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry, Clinical sciences, Biological psychology, Clinical and health psychology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7m63w1d3Test

المؤلفون: Trudler, Dorit, Nazor, Kristopher L, Eisele, Yvonne S, Grabauskas, Titas, Dolatabadi, Nima, Parker, James, Sultan, Abdullah, Zhong, Zhenyu, Goodwin, Marshall S, Levites, Yona, Golde, Todd E, Kelly, Jeffery W, Sierks, Michael R, Schork, Nicholas J, Karin, Michael, Ambasudhan, Rajesh, Lipton, Stuart A

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(15)

مصطلحات موضوعية: Stem Cell Research, Stem Cell Research - Induced Pluripotent Stem Cell, Brain Disorders, Biotechnology, Neurosciences, Neurodegenerative, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Aetiology, 2.1 Biological and endogenous factors, Neurological, Amyloid beta-Peptides, Antibodies, Cell Differentiation, Cells, Cultured, Humans, Induced Pluripotent Stem Cells, Inflammasomes, Microglia, NLR Family, Pyrin Domain-Containing 3 Protein, Parkinson Disease, Toll-Like Receptor 2, alpha-Synuclein, neuroinflammation, Parkinson's disease, Lewy body dementia, Alzheimer's disease, antibody therapies, Alzheimer’s disease, Parkinson’s disease

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6w28067sTest

المؤلفون: Ghatak, Swagata, Dolatabadi, Nima, Trudler, Dorit, Zhang, XiaoTong, Wu, Yin, Mohata, Madhav, Ambasudhan, Rajesh, Talantova, Maria, Lipton, Stuart A

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Neurosciences, Biological Sciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Stem Cell Research - Induced Pluripotent Stem Cell - Human, Dementia, Aging, Stem Cell Research - Induced Pluripotent Stem Cell, Acquired Cognitive Impairment, Neurodegenerative, Stem Cell Research, Alzheimer's Disease, Brain Disorders, Aetiology, 2.1 Biological and endogenous factors, Neurological, Action Potentials, Alzheimer Disease, Amyloid beta-Protein Precursor, Animals, Cell Size, Cells, Cultured, Cerebrum, Cortical Excitability, Electrophysiological Phenomena, Fluorescent Antibody Technique, Humans, Induced Pluripotent Stem Cells, Mice, Models, Theoretical, Mutant Proteins, Neurons, Organoids, Presenilin-1, Alzheimer's disease, cerebral organoids, hiPSC derived neuronal cultures, human, hyperexcitability, neuroscience, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1bt2p40sTest
https://escholarship.org/content/qt1bt2p40s/qt1bt2p40s.pdfTest

المؤلفون: Ryan, Tammy, Bamm, Vladimir V, Stykel, Morgan G, Coackley, Carla L, Humphries, Kayla M, Jamieson-Williams, Rhiannon, Ambasudhan, Rajesh, Mosser, Dick D, Lipton, Stuart A, Harauz, George, Ryan, Scott D

المصدر: Nature Communications. 9(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Stem Cell Research - Induced Pluripotent Stem Cell, Parkinson's Disease, Neurodegenerative, Brain Disorders, Neurosciences, Stem Cell Research, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Neurological, Animals, Antibodies, Monoclonal, Cardiolipins, Cell Communication, Cell Differentiation, Cell Line, Embryonic Stem Cells, Female, Gene Expression, Humans, Induced Pluripotent Stem Cells, Male, Mice, Mice, Transgenic, Microtubule-Associated Proteins, Mitochondria, Mitochondrial Membranes, Mitophagy, Mutation, Neurons, Parkinson Disease, Secondary, Protein Folding, Protein Transport, alpha-Synuclein

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7tn8n9rwTest

المؤلفون: Mann, Aman P, Scodeller, Pablo, Hussain, Sazid, Braun, Gary B, Mölder, Tarmo, Toome, Kadri, Ambasudhan, Rajesh, Teesalu, Tambet, Lipton, Stuart A, Ruoslahti, Erkki

المصدر: Nature Communications. 9(1)

مصطلحات موضوعية: Mathematical Sciences, Statistics, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, Acquired Cognitive Impairment, Brain Disorders, Aging, Neurosciences, Alzheimer's Disease, Dementia

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1q7940ggTest

المؤلفون: Tu, Shichun, Akhtar, Mohd Waseem, Escorihuela, Rosa Maria, Amador-Arjona, Alejandro, Swarup, Vivek, Parker, James, Zaremba, Jeffrey D, Holland, Timothy, Bansal, Neha, Holohan, Daniel R, Lopez, Kevin, Ryan, Scott D, Chan, Shing Fai, Yan, Li, Zhang, Xiaofei, Huang, Xiayu, Sultan, Abdullah, McKercher, Scott R, Ambasudhan, Rajesh, Xu, Huaxi, Wang, Yuqiang, Geschwind, Daniel H, Roberts, Amanda J, Terskikh, Alexey V, Rissman, Robert A, Masliah, Eliezer, Lipton, Stuart A, Nakanishi, Nobuki

المصدر: Nature communications. 8(1)

مصطلحات موضوعية: Brain, Neurons, Synapses, Animals, Mice, Inbred C57BL, Humans, Disease Models, Animal, Memantine, Receptors, N-Methyl-D-Aspartate, Excitatory Amino Acid Antagonists, Gene Expression Profiling, Behavior, Animal, Autistic Disorder, Cell Death, Synaptic Transmission, Down-Regulation, Long-Term Potentiation, Phenotype, Neurogenesis, Haploinsufficiency, MEF2 Transcription Factors, Biomarkers, Mice, Inbred C57BL, Disease Models, Animal, Receptors, N-Methyl-D-Aspartate, Behavior, Autism, Genetics, Mental Health, Stem Cell Research, Intellectual and Developmental Disabilities, Neurosciences, Pediatric, Behavioral and Social Science, Brain Disorders, Stem Cell Research - Nonembryonic - Non-Human, Biotechnology, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Neurological, MD Multidisciplinary

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5127z2zdTest

المؤلفون: Oh, Chang-Ki, Sultan, Abdullah, Platzer, Joseph, Dolatabadi, Nima, Soldner, Frank, McClatchy, Daniel B, Diedrich, Jolene K, Yates, John R, Ambasudhan, Rajesh, Nakamura, Tomohiro, Jaenisch, Rudolf, Lipton, Stuart A

المصدر: Cell Reports. 21(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Brain Disorders, Stem Cell Research - Induced Pluripotent Stem Cell, Aging, Parkinson's Disease, Stem Cell Research, Neurosciences, Neurodegenerative, Genetics, Stem Cell Research - Induced Pluripotent Stem Cell - Human, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Humans, Induced Pluripotent Stem Cells, Mice, Mitochondria, Mitophagy, Mutation, Neurons, Parkinson Disease, Protein Kinases, Ubiquitin-Protein Ligases, PARK2, PARK6, PINK1, Parkin, Parkinson’s disease, S-nitrosylation, mitophagy, Medical Physiology, Biological sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3cq4006fTest

المؤلفون: Mann, Aman P, Scodeller, Pablo, Hussain, Sazid, Braun, Gary B, Mölder, Tarmo, Toome, Kadri, Ambasudhan, Rajesh, Teesalu, Tambet, Lipton, Stuart A, Ruoslahti, Erkki

المصدر: Nature Communications. 8(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Alzheimer's Disease, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Acquired Cognitive Impairment, Neurosciences, Neurodegenerative, Aging, Dementia, 2.1 Biological and endogenous factors, Aetiology, Neurological, Alzheimer Disease, Amyloid beta-Protein Precursor, Animals, Astrocytes, Brain, Connective Tissue Growth Factor, Disease Models, Animal, Hippocampus, Humans, Male, Mice, Mice, Inbred C57BL, Mice, Nude, Mice, Transgenic, Peptide Library, Peptides, Cyclic, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0vv9j75rTest
https://escholarship.org/content/qt0vv9j75r/qt0vv9j75r.pdfTest

المؤلفون: Sunico, Carmen R, Sultan, Abdullah, Nakamura, Tomohiro, Dolatabadi, Nima, Parker, James, Shan, Bing, Han, Xuemei, Yates, John R, Masliah, Eliezer, Ambasudhan, Rajesh, Nakanishi, Nobuki, Lipton, Stuart A

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(47)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Neurodegenerative, Stem Cell Research - Embryonic - Human, Parkinson's Disease, Stem Cell Research, Neurosciences, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Aging, Brain Disorders, Stem Cell Research - Induced Pluripotent Stem Cell, 2.1 Biological and endogenous factors, Aetiology, Neurological, Adenosine Triphosphate, Animals, Brain, Cells, Cultured, Disease Models, Animal, Dopaminergic Neurons, Humans, Hydrolysis, Induced Pluripotent Stem Cells, Mice, Nitric Oxide, Oxidative Stress, Oxidoreductases Acting on Sulfur Group Donors, Parkinson Disease, Peroxiredoxins, Phosphorylation, sulfiredoxin, peroxiredoxin, denitrosylase, iPSC-derived dopaminergic neuron, S-nitrosylation

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/53h1q3qqTest
https://escholarship.org/content/qt53h1q3qq/qt53h1q3qq.pdfTest

المؤلفون: Jiang, Jingjing, Chan, Adriano, Ali, Sameh, Saha, Arindam, Haushalter, Kristofer J, Lam, Wai-Ling Macrina, Glasheen, Megan, Parker, James, Brenner, Matthew, Mahon, Sari B, Patel, Hemal H, Ambasudhan, Rajesh, Lipton, Stuart A, Pilz, Renate B, Boss, Gerry R

المصدر: Scientific reports. 6(1)

مصطلحات موضوعية: Myocardium, Brain, Neurons, Mitochondria, Heart, Fibroblasts, Animals, Mice, Inbred C57BL, Humans, Mice, Rats, Drosophila melanogaster, Hydrogen Sulfide, Hydroxyl Radical, Sulfides, Potassium Cyanide, Cobamides, Electron Transport Complex IV, F2-Isoprostanes, Antidotes, Apoptosis, Cell Differentiation, Oxidative Stress, Male, Induced Pluripotent Stem Cells, Mitochondria, Heart, Inbred C57BL, Nutrition, Stem Cell Research, Neurosciences, Biochemistry and Cell Biology, Other Physical Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9k95f0s4Test