المؤلفون: Amaara Marzook, Alejandra Tomas, Ben Jones

المصدر: Frontiers in Endocrinology, Vol 12 (2021)

مصطلحات موضوعية: GLP-1, GLP-1R, biased agonism, receptor trafficking, pancreatic beta cells, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2021.678055/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/1662f3d7b80d43989facd5835cab39aaTest

المؤلفون: Johannes Broichhagen, James Minnion, Stephen J. Briddon, Joelle Goulding, Yuval Elani, Alejandra Tomas, David J. Hodson, Maria Lucey, Atsuro Oishi, Tanyel Ashik, Ben Jones, Stephen R. Bloom, Ralf Jockers, Amaara Marzook, Yifan Wang

المساهمون: Imperial College London, University of Birmingham [Birmingham], Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Kyorin University School of Medicine [Tokyo, Japan], Kyorin University [Tokyo, Japan], Leibniz Forschungsinstitut für Molekulare Pharmakolgie = Leibniz Institute for Molecular Pharmacology [Berlin, Allemagne] (FMP), Leibniz Association, Department of Chemical Engineering [London], ANR-15-CE14-0025,GlioShuttles4Metabolism,Les tanycytes transportent la leptine dans le cerveau: identification des mécanismes et rôle dans la physiopathologie de l'obésité et du diabète(2015), ANR-19-CE16-0025,mitoGPCR,Les récepteurs couplés aux protéines G mitochondriaux en neuroprotection(2019), Université Paris Cité, Equipe HAL, Les tanycytes transportent la leptine dans le cerveau: identification des mécanismes et rôle dans la physiopathologie de l'obésité et du diabète - - GlioShuttles4Metabolism2015 - ANR-15-CE14-0025 - AAPG2015 - VALID, Les récepteurs couplés aux protéines G mitochondriaux en neuroprotection - - mitoGPCR2019 - ANR-19-CE16-0025 - AAPG2019 - VALID

المصدر: Molecular Pharmacology
Molecular Pharmacology, 2021, 100 (4), pp.319-334. ⟨10.1124/molpharm.121.000270⟩

مصطلحات موضوعية: Male, endocrine system, G protein, Acylation, Endocytic cycle, Incretin, Pharmacology, Endocytosis, Inbred C57BL, Incretins, Glucagon-Like Peptide-1 Receptor, chemistry.chemical_compound, Mice, Downregulation and upregulation, Insulin Secretion, Functional selectivity, Animals, Humans, Cyclic adenosine monophosphate, Receptor, digestive, oral, and skin physiology, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, Mice, Inbred C57BL, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Protein Transport, HEK293 Cells, chemistry, Molecular Medicine, Exenatide, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34511d92a804b7931f16427b2792ca71Test
https://hal.science/hal-03535615/file/319.full.pdfTest

المؤلفون: Ben Jones, Amaara Marzook, Alejandra Tomas

المساهمون: Imperial College Healthcare NHS Trust- BRC Funding, Medical Research Council (MRC), The Academy of Medical Sciences, Society for Endocrinology, European Foundation for the Study of Diabetes, British Society for Neuroendocrinology

المصدر: Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology

مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_treatment, Endocrinology, Diabetes and Metabolism, Review, Biology, pancreatic beta cells, Glucagon-Like Peptide-1 Receptor, Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Glucagon-Like Peptide 1, Insulin-Secreting Cells, medicine, Functional selectivity, Animals, Humans, Endomembrane system, Receptor, G protein-coupled receptor, GLP-1R, Effector, Insulin, digestive, oral, and skin physiology, 1103 Clinical Sciences, receptor trafficking, RC648-665, Glucagon-like peptide-1, Cell biology, Protein Transport, 030104 developmental biology, biased agonism, 1111 Nutrition and Dietetics, GLP-1, 030217 neurology & neurosurgery, Intracellular, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08aa9bfaa4f8fb606abffe77d322e7f6Test
https://www.frontiersin.org/articles/10.3389/fendo.2021.678055/fullTest

المؤلفون: Johannes Broichhagen, Guy A. Rutter, Shiqian Chen, Victoria Salem, Alejandra Tomas, David J. Hodson, Amaara Marzook, Phil Pickford, Ivan R. Corrêa, Ben Jones, Maria Lucey, Tricia Tan, Stephen R. Bloom, Yifan Wang

مصطلحات موضوعية: endocrine system, G protein-coupled receptor kinase, Downregulation and upregulation, Endosome, Kinase, Chemistry, G protein, In vivo, digestive, oral, and skin physiology, Glucose homeostasis, Pharmacology, Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::27acc82a0ed497e3a25f3a2d81b698afTest
https://doi.org/10.1101/2021.04.01.438033Test

المؤلفون: Stephen R. Bloom, Alejandra Tomas, Yifan Wang, James Minnion, Ralf Jockers, David J. Hodson, Stephen J. Briddon, Yuval Elani, Ben Jones, Atsuro Oishi, Joelle Goulding, Johannes Broichhagen, Amaara Marzook, Maria Lucey, Tanyel Ashik

مصطلحات موضوعية: endocrine system, G protein, digestive, oral, and skin physiology, Endocytic cycle, Pharmacology, Endocytosis, chemistry.chemical_compound, chemistry, Downregulation and upregulation, Functional selectivity, Cyclic adenosine monophosphate, Receptor, hormones, hormone substitutes, and hormone antagonists, Glucagon-like peptide 1 receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::bad8725786d001417989336251cf9413Test
https://doi.org/10.1101/2021.04.01.438030Test

المؤلفون: Victoria Salem, Tricia Tan, Alejandra Tomas, David J. Hodson, Johannes Broichhagen, Ben Jones, Shiqian Chen, Ivan R. Corrêa, Stephen R. Bloom, Phil Pickford, Guy A. Rutter, Amaara Marzook, Maria Lucey, Yifan Wang

المساهمون: Imperial College Healthcare NHS Trust- BRC Funding, Medical Research Council (MRC), The Academy of Medical Sciences, Society for Endocrinology, European Foundation for the Study of Diabetes, British Society for Neuroendocrinology, MRC Programme Grant, Wellcome Trust

المصدر: Biochemical Pharmacology

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, Pyridines, G protein, Pharmacology, 0601 Biochemistry and Cell Biology, Biased agonism, Biochemistry, Glucagon-Like Peptide-1 Receptor, Article, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, In vivo, Insulin-Secreting Cells, Functional selectivity, Animals, Humans, Glucose homeostasis, Pharmacology & Pharmacy, Receptor, ComputingMethodologies_COMPUTERGRAPHICS, GLP-1R, G protein-coupled receptor kinase, β-arrestin, Exendin-4, Chemistry, Kinase, digestive, oral, and skin physiology, beta-Arrestin 2, Endocytosis, Mice, Inbred C57BL, 030104 developmental biology, Gene Expression Regulation, 030220 oncology & carcinogenesis, Exenatide, 1115 Pharmacology and Pharmaceutical Sciences, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e995d0e785028d64d373f01df2a61358Test
https://doi.org/10.1016/j.bcp.2021.114656Test