المؤلفون: Marlous Kamp, Jakub Surmacki, Marc Segarra Mondejar, Tim Young, Karolina Chrabaszcz, Fadwa Joud, Vincent Zecchini, Alyson Speed, Christian Frezza, Sarah E. Bohndiek

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/8659ea9da0fc40959c45b06746f55cb7Test

المؤلفون: Lorea Valcarcel-Jimenez, Connor Rogerson, Cissy Yong, Christina Schmidt, Ming Yang, Monica Cremades-Rodelgo, Victoria Harle, Victoria Offord, Kim Wong, Ariane Mora, Alyson Speed, Veronica Caraffini, Maxine Gia Binh Tran, Eamonn R. Maher, Grant D. Stewart, Sakari Vanharanta, David J. Adams, Christian Frezza

المصدر: Science Advances. 8

مصطلحات موضوعية: Multidisciplinary

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e25b92f275d4c9db74028e103d2d9b90Test
https://doi.org/10.1126/sciadv.abq8297Test

المؤلفون: Meiling Gao, Emma M. Kerr, Alyson Speed, Jake Cridge, David Shorthouse, Carla P. Martins, Gary J. Doherty, Benjamin A. Hall, Meryl Griffiths, Shamith A. Samarajiwa, Frances K. Turrell, Hannah Thorpe

المساهمون: Doherty, Gary [0000-0002-8158-8111], Shorthouse, David [0000-0002-3207-3584], Samarajiwa, Shamith [0000-0003-1046-0601], Hall, Benjamin [0000-0003-0355-2946], Apollo - University of Cambridge Repository

المصدر: Turrell, F K, Kerr, E M, Gao, M, Thorpe, H, Doherty, G J, Cridge, J, Shorthouse, D, Speed, A, Samarajiwa, S, Hall, B A, Griffiths, M & Martins, C P 2017, ' Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity ', Genes & development, vol. 31, no. 13, pp. 1339-1353 . https://doi.org/10.1101/gad.298463.117Test

مصطلحات موضوعية: 0301 basic medicine, Simvastatin, Lung Neoplasms, medicine.medical_treatment, Mutant, p53 restoration, medicine.disease_cause, Piperazines, Targeted therapy, Loss of heterozygosity, Mice, 0302 clinical medicine, transcriptome analysis, Genotype, Molecular Targeted Therapy, Mutation, Cell Death, mutant p53, Imidazoles, Phenotype, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Adenocarcinoma, Research Paper, Adenocarcinoma of Lung, Antineoplastic Agents, Biology, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Genetics, medicine, Animals, Lung cancer, therapy, mevalonate pathway, Cell Cycle Checkpoints, medicine.disease, Disease Models, Animal, 030104 developmental biology, Drug Resistance, Neoplasm, Immunology, Cancer research, lung tumors, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Tumor Suppressor Protein p53, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3777114bdf1f64bef7952eb1b2e9f5dTest