المؤلفون: ODonoghue, Anthony, Gerwick, William, Almaliti, Jehad, Alhindy, Momen, Yoon, Michael, Hook, Vivian, Molinski, Tadeusz

المصدر: ACS Omega. 9(3)

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4sv8s9jkTest

المؤلفون: Almaliti, Jehad, Fajtová, Pavla, Calla, Jaeson, LaMonte, Gregory M, Feng, Mudong, Rocamora, Frances, Ottilie, Sabine, Glukhov, Evgenia, Boura, Evzen, Suhandynata, Raymond T, Momper, Jeremiah D, Gilson, Michael K, Winzeler, Elizabeth A, Gerwick, William H, O'Donoghue, Anthony J

المصدر: Chemistry - A European Journal. 29(20)

مصطلحات موضوعية: Chemical Sciences, Orphan Drug, Rare Diseases, Vector-Borne Diseases, Infectious Diseases, Malaria, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Mice, Animals, Humans, Proteasome Inhibitors, Proteasome Endopeptidase Complex, Plasmodium, Plasmodium falciparum, Antimalarials, epoxyketone, inhibition, malaria, plasmodium, proteasome, General Chemistry, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6x99c667Test

المؤلفون: Spiwoková, Petra, Horn, Martin, Fanfrlík, Jindřich, Jílková, Adéla, Fajtová, Pavla, Leontovyč, Adrian, Houštecká, Radka, Bieliková, Lucia, Brynda, Jiří, Chanová, Marta, Mertlíková-Kaiserová, Helena, Caro-Diaz, Eduardo J. E., Almaliti, Jehad, El-Sakkary, Nelly, Gerwick, William H., Caffrey, Conor R., Mareš, Michael

المساهمون: Ministerstvo Školství, Mládeže a Telovýchovy, National Institute of Allergy and Infectious Diseases, Akademie Ved Ceské Republiky, Ministerstvo Zdravotnictví Ceské Republiky, Univerzita Karlova v Praze

المصدر: ACS Infectious Diseases ; volume 10, issue 6, page 1935-1948 ; ISSN 2373-8227 2373-8227

الإتاحة: https://doi.org/10.1021/acsinfecdis.3c00589Test

المؤلفون: Almaliti, Jehad, Alhindy, Momen, Yoon, Michael C., Hook, Vivian, Molinski, Tadeusz F., O’Donoghue, Anthony J., Gerwick, William H.

المساهمون: National Institute of Neurological Disorders and Stroke, St. Baldrick's Foundation

المصدر: ACS Omega ; ISSN 2470-1343 2470-1343

مصطلحات موضوعية: General Chemical Engineering, General Chemistry

الإتاحة: https://doi.org/10.1021/acsomega.3c08629Test

المؤلفون: Keller, Lena, Canuto, Kirley Marques, Liu, Chenxi, Suzuki, Brian M, Almaliti, Jehad, Sikandar, Asfandyar, Naman, C Benjamin, Glukhov, Evgenia, Luo, Danmeng, Duggan, Brendan M, Luesch, Hendrik, Koehnke, Jesko, O’Donoghue, Anthony J, Gerwick, William H

المصدر: ACS Chemical Biology. 15(3)

مصطلحات موضوعية: Amino Acids, Aminobutyrates, Antineoplastic Agents, Cell Line, Tumor, Cell Survival, Chromatography, High Pressure Liquid, Cyanobacteria, Depsipeptides, Drug Screening Assays, Antitumor, Enzyme Inhibitors, Humans, Lung Neoplasms, Models, Molecular, Molecular Structure, Pancreatic Elastase, Peptides, Cyclic, Piperidones, Protein Binding, Tandem Mass Spectrometry, Vinyl Chloride, Chemical Sciences, Biological Sciences, Organic Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8qs975j2Test

المؤلفون: O'Donoghue, Anthony J, Bibo-Verdugo, Betsaida, Miyamoto, Yukiko, Wang, Steven C, Yang, Justin Z, Zuill, Douglas E, Matsuka, Shoun, Jiang, Zhenze, Almaliti, Jehad, Caffrey, Conor R, Gerwick, William H, Eckmann, Lars

المصدر: Antimicrobial Agents and Chemotherapy. 63(11)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Infectious Diseases, Sexually Transmitted Infections, Biotechnology, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Amino Acid Sequence, Animals, Anti-Infective Agents, Antitrichomonal Agents, Cytoplasm, Drug Resistance, Female, Humans, Mice, Mice, Inbred BALB C, Parasitic Sensitivity Tests, Proteasome Endopeptidase Complex, Proteomics, Sexually Transmitted Diseases, Trichomonas Infections, Trichomonas Vaginitis, Trichomonas vaginalis, proteasome, protozoa, Trichomonas vaginalis, Microbiology, Medical Microbiology, Pharmacology and Pharmaceutical Sciences, Medical microbiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2bk3t711Test

المؤلفون: Boudreau, Paul D, Miller, Bailey W, McCall, Laura-Isobel, Almaliti, Jehad, Reher, Raphael, Hirata, Ken, Le, Thu, Siqueira-Neto, Jair L, Hook, Vivian, Gerwick, William H

المصدر: Journal of Medicinal Chemistry. 62(20)

مصطلحات موضوعية: Rare Diseases, Vector-Borne Diseases, Orphan Drug, Infectious Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Good Health and Well Being, Antimicrobial Cationic Peptides, Cathepsin L, Cysteine Endopeptidases, Cysteine Proteinase Inhibitors, Drug Design, Humans, Kinetics, Molecular Docking Simulation, Protozoan Proteins, Trypanosoma cruzi, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6cf074w4Test

المؤلفون: Bibo-Verdugo, Betsaida, Wang, Steven C, Almaliti, Jehad, Ta, Anh P, Jiang, Zhenze, Wong, Derek A, Lietz, Christopher B, Suzuki, Brian M, El-Sakkary, Nelly, Hook, Vivian, Salvesen, Guy S, Gerwick, William H, Caffrey, Conor R, O’Donoghue, Anthony J

المصدر: ACS Infectious Diseases. 5(10)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Rare Diseases, Infectious Diseases, Vector-Borne Diseases, Digestive Diseases, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Good Health and Well Being, Animals, Antineoplastic Agents, Bortezomib, Caspases, Cysteine Proteinase Inhibitors, Drug Delivery Systems, Hep G2 Cells, Humans, Leupeptins, Oligopeptides, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Schistosoma mansoni, proteasome, Schistosoma, schistosomiasis, bortezomib, catfilzomib, carmaphycin, MG132, carfilzomib, Medical microbiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/15g414twTest

المؤلفون: Almaliti, Jehad, Miller, Bailey, Pietraszkiewicz, Halina, Glukhov, Evgenia, Naman, C Benjamin, Kline, Toni, Hanson, Jeffrey, Li, Xiaofan, Zhou, Sihong, Valeriote, Frederick A, Gerwick, William H

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Biotechnology, Cancer, Orphan Drug, Rare Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Amines, Aniline Compounds, Antibodies, Monoclonal, Antineoplastic Agents, Cell Line, Tumor, Cell Proliferation, Cell Survival, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Humans, Molecular Structure, Oligopeptides, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Structure-Activity Relationship, Anticancer drugs, Proteasome inhibitors, Antibody-drug conjugate, Amine basicity optimization, 4-Sulfonylaniline, Carmaphycins, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/68n297qnTest

المؤلفون: Deni, Ioanna, Stokes, Barbara H., Ward, Kurt E., Fairhurst, Kate J., Pasaje, Charisse Flerida A., Yeo, Tomas, Akbar, Shirin, Park, Heekuk, Muir, Ryan, Bick, Daniella S., Zhan, Wenhu, Zhang, Hao, Liu, Yi Jing, Ng, Caroline L., Kirkman, Laura A., Almaliti, Jehad, Gould, Alexandra E., Duffey, Maëlle, O'Donoghue, Anthony J., Uhlemann, Anne-Catrin, Niles, Jacquin C., da Fonseca, Paula C. A., Gerwick, William H., Lin, Gang, Bogyo, Matthew, Fidock, David A.

وصف الملف: text

العلاقة: https://eprints.gla.ac.uk/296042/1/296042.pdfTest; Deni, I. et al. (2023) Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chemical Biology , 30(5), 470-485.e6. (doi:10.1016/j.chembiol.2023.03.002 ) (PMID:36963402) (PMCID:PMC10198959)

الإتاحة: https://doi.org/10.1016/j.chembiol.2023.03.002Test
https://eprints.gla.ac.uk/296042Test/
https://eprints.gla.ac.uk/296042/1/296042.pdfTest