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1دورية أكاديمية
المؤلفون: Lisa Barbaro, Alice L. Rodriguez, Ashlyn N. Blevins, Jonathan W. Dickerson, Natasha Billard, Olivier Boutaud, Jerri L. Rook, Colleen M. Niswender, P.Jeffrey Conn, Darren W. Engers, Craig W. Lindsley
المصدر: ACS Bio & Med Chem Au, Vol 1, Iss 1, Pp 21-30 (2021)
مصطلحات موضوعية: Biology (General), QH301-705.5, Biochemistry, QD415-436
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2694-2437Test
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2دورية أكاديمية
المؤلفون: Christopher C. Presley, Charles K. Perry, Elizabeth S. Childress, Matthew J. Mulder, Vincent B. Luscombe, Alice L. Rodriguez, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley
المصدر: ACS Omega, Vol 4, Iss 7, Pp 12782-12789 (2019)
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2470-1343Test
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3دورية أكاديمية
المؤلفون: Mark S. Moehle (11217998), Aaron M. Bender (5155397), Jonathan W. Dickerson (3628004), Daniel J. Foster (4760043), Aidong Qi (2204728), Hyekyung P. Cho (59088), Yuping Donsante (11218001), Weimin Peng (2649190), Zoey Bryant (11218004), Kaylee J. Stillwell (11218007), Thomas M. Bridges (1336731), Sichen Chang (1475053), Katherine J. Watson (11218010), Jordan C. O’Neill (3778144), Julie L. Engers (1475044), Li Peng (83452), Alice L. Rodriguez (1270236), Colleen M. Niswender (353419), Craig W. Lindsley (203380), Ellen J. Hess (11218013), P. Jeffrey Conn (1270239), Jerri M. Rook (1315593)
مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Molecular Biology, Neuroscience, Pharmacology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, nonselective mAChR antagonists, mAChR knockout animals, M 4 receptor activation, subtype, movement disorders, nonselective antimuscarinic therape., muscarinic acetylcholine receptors, M 4 Muscarinic Acetylcholine Recept., M 4, antiparkinsonian, M 4 muscarinic acetylcholine receptor, role, VU, antidystonic efficacy, Antidystonic Efficacy Nonselective ., model
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4دورية أكاديمية
المؤلفون: Matthew Spock (11219123), Trever R. Carter (11219126), Katrina A. Bollinger (4375849), Changho Han (1309563), Logan A. Baker (11219129), Alice L. Rodriguez (1270236), Li Peng (83452), Jonathan W. Dickerson (3628004), Aidong Qi (2204728), Jerri M. Rook (1315593), Jordan C. O’Neill (3778144), Katherine J. Watson (11218010), Sichen Chang (1475053), Thomas M. Bridges (1336731), Julie L. Engers (1475044), Darren W. Engers (655505), Colleen M. Niswender (353419), P. Jeffrey Conn (1270239), Craig W. Lindsley (203380), Aaron M. Bender (5155397)
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Evolutionary Biology, Sociology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, novel use, DMPK properties, movement disorders, Orally Bioavailable M 4 Muscarinic ., CYP inhibition, deuterium incorporation, SAR, M 4 mAChR antagonist, VU 6028418
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5دورية أكاديمية
المؤلفون: Lisa Barbaro (1801921), Alice L. Rodriguez (1270236), Ashlyn N. Blevins (11569318), Jonathan W. Dickerson (3628004), Natasha Billard (11569321), Olivier Boutaud (1340007), Jerri L. Rook (11569324), Colleen M. Niswender (353419), P.Jeffrey Conn (11569327), Darren W. Engers (655505), Craig W. Lindsley (203380)
مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, site binding nam, regioisomeric methyl congener, allosteric privileged structures, allosteric ligands driven, 94 ), mpep, 83 ), p sub, 50 sub, 5 sub, 1 sub, 28d b, 17a b, site binding mglu, displayed anxiolytic activity, vivo <, reversed amphetamine, pure mglu, literature concerning, induced hyperlocomotion, growing body
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المؤلفون: Sichen Chang, Jonathan W. Dickerson, Baker Logan A, Thomas M. Bridges, Craig W. Lindsley, Darren W. Engers, Aidong Qi, Jerri M. Rook, Aaron M. Bender, P. Jeffrey Conn, Katrina A. Bollinger, Colleen M. Niswender, Changho Han, Alice L. Rodriguez, Trever R Carter, Li Peng, Julie L. Engers, Jordan C. O’Neill, Matthew Spock, Katherine J. Watson
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Dystonia, Movement disorders, Chemistry, Organic Chemistry, Antagonist, Pharmacology, medicine.disease, Highly selective, Biochemistry, In vitro, Bioavailability, In vivo, Drug Discovery, Muscarinic acetylcholine receptor, medicine, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388290e5061b99e6a85f95357b9a3b32Test
https://doi.org/10.1021/acsmedchemlett.1c00363Test -
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المؤلفون: Jerri M. Rook, Aaron M. Bender, Colleen M. Niswender, Yuping Donsante, P. Jeffrey Conn, Hyekyung P. Cho, Li Peng, Julie L. Engers, Jonathan W. Dickerson, Thomas M. Bridges, Craig W. Lindsley, Ellen J. Hess, Sichen Chang, Aidong Qi, Weimin Peng, Mark S. Moehle, Jordan C. O’Neill, Daniel J. Foster, Alice L. Rodriguez, Zoey Bryant, Katherine J. Watson, Kaylee J. Stillwell
المصدر: ACS Pharmacology & Translational Science. 4:1306-1321
مصطلحات موضوعية: Pharmacology, Dystonia, Movement disorders, business.industry, Central nervous system, medicine.disease, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Tolerability, In vivo, Muscarinic acetylcholine receptor, Genetic model, Medicine, Pharmacology (medical), medicine.symptom, business, Neurotransmitter
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f5425dfe0a6fb74da410878130ec6660Test
https://doi.org/10.1021/acsptsci.0c00162Test -
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المؤلفون: Darren W. Engers, Natasha Billard, Colleen M. Niswender, Ashlyn N. Blevins, Olivier Boutaud, Jonathan W. Dickerson, P. Jeffrey Conn, Jerri L. Rook, Craig W. Lindsley, Alice L. Rodriguez, Lisa Barbaro
المصدر: ACS Bio & Med Chem Au, Vol 1, Iss 1, Pp 21-30 (2021)
مصطلحات موضوعية: Molecular switch, Chemotype, Chemistry, Stereochemistry, QH301-705.5, Allosteric regulation, Magic (programming), Pharmaceutical Science, QD415-436, Biochemistry, In vivo, Drug Discovery, Biology (General), Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6207100701021f062c871e381bbd20fTest
https://doaj.org/article/a1962d9086d84ecabe40eff8d58cb02fTest -
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المؤلفون: Jacob J, Kalbfleisch, Alice L, Rodriguez, Xia, Lei, Kelly, Weiss, Annie L, Blobaum, Olivier, Boutaud, Colleen M, Niswender, Craig W, Lindsley
المصدر: Bioorganicmedicinal chemistry letters. 80
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::cecb28e2b56f8278abdd8546cdd49441Test
https://pubmed.ncbi.nlm.nih.gov/36528230Test -
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المؤلفون: Douglas L, Orsi, Andrew S, Felts, Alice L, Rodriguez, Paige N, Vinson, Hyekyung P, Cho, Sichen, Chang, Anna L, Blobaum, Colleen M, Niswender, P Jeffrey, Conn, Carrie K, Jones, Craig W, Lindsley, Changho, Han
المصدر: Bioorganicmedicinal chemistry letters. 78
مصطلحات موضوعية: Kinetics, Pyrrolidines, Muscarinic Antagonists, Amides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::ba1ae3207bee2690b73570a55f8a56c4Test
https://pubmed.ncbi.nlm.nih.gov/36228968Test