Effects of Armolipid Plus on small dense LDL particles in a sample of patients affected by familial combined hyperlipidemia
| العنوان: | Effects of Armolipid Plus on small dense LDL particles in a sample of patients affected by familial combined hyperlipidemia |
|---|---|
| المؤلفون: | Carmen Pagano, Gennaro Marotta, Paolo Rubba, Marco Gentile, E. Speranza, Ilenia Calcaterra, Alfonso Strazzullo, Delia Pacioni |
| المساهمون: | Gentile, M, Calcaterra, I, Strazzullo, A, Pagano, C, Pacioni, Delia, Speranza, E, Rubba, PAOLO OSVALDO FEDERICO, Marotta, G. |
| المصدر: | Clinical Lipidology. 10:475-480 |
| بيانات النشر: | Informa UK Limited, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | medicine.medical_specialty, Small dense ldl, business.industry, Endocrinology, Diabetes and Metabolism, Placebo, Placebo group, Gastroenterology, Article, Familial combined hyperlipidemia, Endocrinology, Internal medicine, Particle diameter, medicine, Standard diet, In patient, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Aim: The aim of this study was to test small dense LDL changes with Armolipid Plus treatment in patients with familial combined hyperlipidemia (FCHL). Methods: After 4 weeks, 30 patients with FCHL were included in an 8-week, randomized, double-blind study and were taking, in addition to the standard diet, either placebo or Armolipid Plus. Results: The placebo group showed no statistically significant differences in the studied parameters; instead, in the Armolipid Plus group, statistically significant reduction differences were detected in BMI (p = 0.010), LDL score (p = 0.035) and an increase in mean LDL particle diameter (p = 0.040). Conclusion: The combination of a standard diet with Armolipid Plus is able to reduce LDL score and increase LDL particle diameter in a group of FCHL after 8 weeks of treatment. |
| تدمد: | 1758-4302 1758-4299 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ce57c531564ad28699e1e81d700eafTest https://doi.org/10.2217/clp.15.37Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....86ce57c531564ad28699e1e81d700eaf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17584302 17584299 |
|---|