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المؤلفون: Robert S. T. Charles, Alexander Tulinsky, Kaillathe Padmanabhan, R. V. Arni, K.P. Padmanabhan
المساهمون: Michigan State University, Universidade Estadual Paulista (Unesp)
المصدر: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESPمصطلحات موضوعية: Protein Conformation, Lysine, Crystal structure, anticoagulant agent, Crystallography, X-Ray, Biochemistry, Ticks, Protein structure, Native state, peptide analysis, Acari, Peptide sequence, Factor Xa, tick anticoagulant peptide, Hydrogen bond, Chemistry, tick, priority journal, Factor Xa, Intercellular Signaling Peptides and Proteins, Research Article, Conformational changes, aprotinin, blood clotting factor 10a, crystal structure, Macromolecular Substances, Stereochemistry, Static Electricity, Molecular Sequence Data, In Vitro Techniques, blood clotting, Bovinae, Arthropod Proteins, Aprotinin, Electrostatics, Animals, Molecule, tetrapeptide, Amino Acid Sequence, Molecular Biology, hydrogen bond, nonhuman, Tetrapeptide, Hydrogen Bonding, X ray crystallography, Crystallography, molecular interaction, Bovine pancreatic trypsin inhibitor, Cattle, Peptides, Factor Xa Inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fb29b1683ff8f984460536c13d29b6Test
https://doi.org/10.1110/ps.9.2.265Test -
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المصدر: Journal of Molecular Biology. 371:774-786
مصطلحات موضوعية: Models, Molecular, Ancylostoma, Stereochemistry, Lipoproteins, Molecular Sequence Data, Protein Structure, Secondary, Tissue factor pathway inhibitor, Structural Biology, Catalytic Domain, Hydrolase, Catalytic triad, medicine, Animals, Humans, Amino Acid Sequence, Molecular Biology, Binding Sites, Pancreatic Elastase, biology, Chemistry, Hydrogen bond, Anticoagulants, Active site, Helminth Proteins, biology.organism_classification, Trypsin, Protein Structure, Tertiary, Nematode, Biochemistry, Factor Xa, biology.protein, Ancylostoma caninum, 1-Carboxyglutamic Acid, Sequence Alignment, Factor Xa Inhibitors, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc03bdaeb337dcca26f84493de859bf7Test
https://doi.org/10.1016/j.jmb.2007.05.042Test -
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المؤلفون: B. J. Bell, Leandra Watanabe, Lukasz Lebioda, J. L. Rios-Steiner, Raghuvir K. Arni, Alexander Tulinsky
المصدر: Acta Crystallographica Section D Biological Crystallography. 59:1454-1458
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Trimer, Biology, Crystallography, X-Ray, Cleavage (embryo), Protein Structure, Secondary, Phosphates, Structural Biology, Escherichia coli, Organic chemistry, Aldehyde-Lyases, chemistry.chemical_classification, Binding Sites, Pseudomonas putida, Lysine, Aldolase A, Active site, General Medicine, Lyase, biology.organism_classification, Protein Structure, Tertiary, Enzyme, chemistry, Helix, biology.protein, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b048b04f7a3144d92223f21d655378beTest
https://doi.org/10.1107/s0907444903013192Test -
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المؤلفون: Mark Warnock, Raman Krishnan, Fakhri Mahdi, Alvin H. Schmaier, Ahmed A. K. Hasan, Alexander Tulinsky, Marvin T. Nieman, Sujata Srikanth
المصدر: American Journal of Physiology-Heart and Circulatory Physiology. 285:H183-H193
مصطلحات موضوعية: Blood Platelets, Models, Molecular, DNA, Complementary, Physiology, Molecular Conformation, Bradykinin, Peptide, In Vitro Techniques, Hemostatics, chemistry.chemical_compound, Thrombin, Physiology (medical), Crotalid Venoms, Thrombin receptor, medicine, Humans, Receptor, PAR-1, Platelet activation, chemistry.chemical_classification, biology, Chemistry, Serine Endopeptidases, Anticoagulants, Biological activity, Peptide Fragments, Kinetics, Mechanism of action, Biochemistry, Enzyme inhibitor, Mutagenesis, Site-Directed, biology.protein, Receptors, Thrombin, medicine.symptom, Peptides, Cardiology and Cardiovascular Medicine, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c248c30d79f3a1cd795f3cb872dcddbdTest
https://doi.org/10.1152/ajpheart.00490.2002Test -
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المؤلفون: Francis J. Castellino, James H. Geiger, Raghuvir K. Arni, Marta C. Abad, Davida K. Grella, Alexander Tulinsky
المصدر: Journal of Molecular Biology. 318:1009-1017
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Angiogenesis, Stereochemistry, Bicine, Molecular Sequence Data, Angiogenesis Inhibitors, Peptide, Crystallography, X-Ray, Pichia, Kringle domain, chemistry.chemical_compound, Kringles, Structural Biology, Hydrolase, Humans, Amino Acid Sequence, Binding site, Angiostatins, Molecular Biology, chemistry.chemical_classification, Angiostatin, Sequence Homology, Amino Acid, Plasminogen, Peptide Fragments, Angiogenesis inhibitor, chemistry, Mutation, Crystallization
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa018126762529840344688034931caTest
https://doi.org/10.1016/s0022-2836Test(02)00211-5 -
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المؤلفون: Alexander Tulinsky, Raman Krishnan, J E Sadler
المصدر: Acta Crystallographica Section D Biological Crystallography. 56:406-410
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Proteolysis, Mutant, Crystallography, X-Ray, Cleavage (embryo), Catalysis, Thrombin, Structural Biology, Hydrolase, Serine, medicine, Humans, Point Mutation, Peptide bond, Fibrinopeptide A, Alanine, Binding Sites, biology, medicine.diagnostic_test, Chemistry, Active site, General Medicine, Hirudins, Peptide Fragments, Amino Acid Substitution, biology.protein, Software, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2950b620b4c25d8b223f56b3b6c1950cTest
https://doi.org/10.1107/s0907444900001487Test -
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المؤلفون: Irene M. Mavridis, Alexander Tulinsky, Stella Makedonopoulou
المصدر: Supramolecular Chemistry. 11:73-81
مصطلحات موضوعية: chemistry.chemical_classification, Solvent, chemistry.chemical_compound, Crystallography, Tridecanedioic acid, chemistry, Cyclodextrin, Stereochemistry, Dimer, Carboxylic acid, Molecule, General Chemistry, Beta (finance)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0b109839d82be660907dfaedcb53f72aTest
https://doi.org/10.1080/10610279908048718Test -
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المؤلفون: J.H. Matthews, E. Zhang, R St Charles, Alexander Tulinsky
المصدر: Journal of Medicinal Chemistry. 42:1376-1383
مصطلحات موضوعية: Models, Molecular, Serine Proteinase Inhibitors, Molecular model, Stereochemistry, Beta sheet, Crystallography, X-Ray, Protein Structure, Secondary, Scissile bond, Thrombin, Drug Discovery, medicine, Binding site, Aza Compounds, Binding Sites, biology, Chemistry, Molecular Mimicry, Active site, Bridged Bicyclo Compounds, Heterocyclic, Enzyme inhibitor, biology.protein, Molecular Medicine, Peptides, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26996ad446b820ebd80d055492ea9ff9Test
https://doi.org/10.1021/jm980052nTest -
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المؤلفون: Robert S. T. Charles, Erli Zhang, Alexander Tulinsky
المصدر: Journal of Molecular Biology. 285:2089-2104
مصطلحات موضوعية: biology, Chemistry, Mutant, Active site, macromolecular substances, Small molecule, Tissue factor, Tissue factor pathway inhibitor, Coagulation, Biochemistry, Structural Biology, otorhinolaryngologic diseases, biology.protein, sense organs, Salt bridge, Kunitz domain, Molecular Biology, circulatory and respiratory physiology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::49f26c811a6e818b2c7740e27b18f620Test
https://doi.org/10.1006/jmbi.1998.2452Test -
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المؤلفون: K. Hakansson, Alexander Tulinsky, J. E. Semple, Raman Krishnan, O. E. Levy, E. Zhang, Terence K. Brunck, Raghuvir K. Arni, M. S. L. Lim-Wilby
المصدر: Biochemistry. 37:12094-12103
مصطلحات موضوعية: Models, Molecular, Serine Proteinase Inhibitors, Macromolecular Substances, Stereochemistry, Kinetics, Glycine, Molecular Conformation, Guanidines, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Thrombin, Piperidines, medicine, Animals, Humans, Moiety, Trypsin, Binding site, Aldehydes, Binding Sites, Chemistry, Lactam, Cattle, Trypsin Inhibitors, Selectivity, medicine.drug, Discovery and development of direct thrombin inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0732b7de9baad587a518c7a6f625817bTest
https://doi.org/10.1021/bi980840eTest