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1دورية أكاديمية
المؤلفون: Ryan P. Staupe, Kenneth E. Lodge, Nithya Thambi, David Toole, Alex M. Tamburino, Dan Chang, Bonnie J. Howell, Daria J. Hazuda, Kalpit A. Vora, Nicole L. Sullivan
المصدر: Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2399-3642Test
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المؤلفون: Sam V Machotka, Frank D. Sistare, Amy G. Aslamkhan, Alex M Tamburino, Todd Pippert, Raymond Evers, Kaushik Mitra, Keith Q. Tanis, Timothy E. Johnson, Donna Lynch, Wen Kang, Truyen Nguyen, Randy R. Miller, James J Monroe, Tamara D. Cabalu, Alexei A. Podtelezhnikov, Nancy G. B. Agrawal, Jairam Palamanda
المصدر: Toxicological Sciences
مصطلحات موضوعية: Male, 0301 basic medicine, Drug, Pharmaceutical drug, AcademicSubjects/SCI01040, drug safety, NF-E2-Related Factor 2, media_common.quotation_subject, medicine.medical_treatment, Pharmacology, lead optimization, Toxicology, 030226 pharmacology & pharmacy, NRF1, NRF2, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Drug Development, In vivo, Animals, Medicine, transcriptional biomarkers, Rats, Wistar, Regulatory Science, Risk Assessment, and Decision Making, media_common, Liver injury, bioactivation, drug candidate attrition, Kelch-Like ECH-Associated Protein 1, AcademicSubjects/MED00305, business.industry, medicine.disease, KEAP1, Rats, rat liver, 030104 developmental biology, Pharmaceutical Preparations, Drug development, Biomarker (medicine), Chemical and Drug Induced Liver Injury, business, drug-induced liver injury, chemically reactive metabolites
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2892a55e03df13402f0ef50b67f49d4bTest
https://doi.org/10.1093/toxsci/kfaa088Test -
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المؤلفون: Alex M. Tamburino, Weilong Zhao, Ashmita Saigal, Peyvand Amini, Sunhwa Kim, Maarten Hoek, Subharekha Raghavan
المصدر: Archives of Proteomics and Bioinformatics. 1
مصطلحات موضوعية: Anti fibrotic, medicine.anatomical_structure, Fibrosis, Activator (genetics), Chemistry, medicine, Cancer research, medicine.disease, Fibroblast, Human lung, Guanylate cyclase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0fed36a89cfdc4a66de767c7be42ed58Test
https://doi.org/10.33696/proteomics.1.003Test -
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المؤلفون: Subharekha Raghavan, Ashmita Saigal, Peyvand Amini, Alex M. Tamburino, Sunhwa Kim, Maarten Hoek, Weilong Zhao
مصطلحات موضوعية: Lung, Activator (genetics), business.industry, medicine.disease, Pulmonary hypertension, Idiopathic pulmonary fibrosis, medicine.anatomical_structure, Fibrosis, Pulmonary fibrosis, medicine, Cancer research, Phosphorylation, business, Transforming growth factor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ab298bb2c71dba195bbf60bbe99673b7Test
https://doi.org/10.1101/2020.06.12.148908Test -
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المؤلفون: José A. Lebrón, Donna Lynch, Kristin Geddes, Stephen Pacchione, Hong Duong, Yutai Li, Warren E. Glaab, Alema Galijatovic-Idrizbegovic, Frank D. Sistare, Wen Kang, Raymond J. Gonzalez, Daniel J. Holder, Kyeongmi Cheon, Kara Pearson, Nanyan Rena Zhang, Alex M Tamburino, Michael J. Hafey, Raymond Evers, Keith Q. Tanis, Lisa LaFranco-Scheuch
المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 170(1)
مصطلحات موضوعية: 0301 basic medicine, Male, Taurine, Bilirubin, medicine.drug_class, Glycocholic acid, Pharmacology, Toxicology, Taurochenodeoxycholic Acid, 03 medical and health sciences, Benzbromarone, chemistry.chemical_compound, 0302 clinical medicine, medicine, Animals, RNA, Small Interfering, Rats, Wistar, ATP Binding Cassette Transporter, Subfamily B, Member 11, Transaminases, Liver injury, Bile acid, medicine.disease, Bile Salt Export Pump, Acetaminophen, Rats, Disease Models, Animal, 030104 developmental biology, chemistry, Pharmaceutical Preparations, Gene Knockdown Techniques, Chemical and Drug Induced Liver Injury, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0bf4d9d28084bd888d7572b62cf84eTest
https://pubmed.ncbi.nlm.nih.gov/30903168Test -
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المؤلفون: Frank D. Sistare, Warren E. Glaab, Lisa LaFranco-Scheuch, Kyeongmi Cheon, Alex M Tamburino, Michael J. Hafey, Raymond Evers, Hong Duong, Yutai Li, Kara Pearson, José A. Lebrón
المصدر: Drug Metabolism and Pharmacokinetics. 35:S93
مصطلحات موضوعية: Pharmacology, Drug, Gene knockdown, Liver toxicity, Chemistry, Mechanism (biology), media_common.quotation_subject, Pharmaceutical Science, Pharmacology (medical), Bile Salt Export Pump, media_common
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::60b6c04083f0281e512be6217e2daea5Test
https://doi.org/10.1016/j.dmpk.2020.04.235Test -
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المؤلفون: Albertha J.M. Walhout, Alex M. Tamburino, Ebru Kaymak, Shaleen Shrestha, Amy D. Holdorf, Sean P. Ryder
مصطلحات موضوعية: 0301 basic medicine, endocrine system, RNA-binding protein, Computational biology, Biology, Biochemistry, Interactome, chemistry.chemical_compound, 03 medical and health sciences, 0302 clinical medicine, Methods Article, Molecular Biology, Transcription factor, Gene, 030304 developmental biology, Regulation of gene expression, 0303 health sciences, Messenger RNA, Rna protein, Chemistry, 030302 biochemistry & molecular biology, RNA, Cell Biology, humanities, 030104 developmental biology, 030217 neurology & neurosurgery, DNA, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cc77d7eb4d4226b498e1a6bf396ab6Test
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المؤلفون: Juan I. Fuxman Bass, Alex M. Tamburino, John S. Reece-Hoyes, Albertha J.M. Walhout, Akihiro Mori, Nathan Beittel, Matthew T. Weirauch
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Regulation of gene expression, Genetics, Intron, Promoter, Gene Regulation, Chromatin and Epigenetics, Biology, biology.organism_classification, Introns, Gene Expression Regulation, Regulatory sequence, Multigene Family, Animals, Gene Regulatory Networks, Caenorhabditis elegans, Promoter Regions, Genetic, Gene, Transcription factor, Chromatin immunoprecipitation, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b251f2ffa9b2a703b68a769ce1490bTest
https://doi.org/10.1093/nar/gkt858Test -
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المؤلفون: Zining Wu, Sibongile Mataruse, Alex M. Tamburino, Gang Yao, Jeffrey A. Messer, Yun Ding, Jean Zhang, G Joseph Franklin, Jianghe Deng, Todd L. Graybill, Xin Zeng, David D. Wisnoski, Frank T. Coppo, David I. Israel, Genaro S. Scavello, Jennifer Summerfield, Andrew J. Pope, Michael Platchek, Vera Q. Bodmer, Paolo A. Centrella, Jing Chai, Katie L Sargent Bedard
المصدر: ACS combinatorial science. 17(12)
مصطلحات موضوعية: Cell, Computational biology, Acetates, Ligands, Small Molecule Libraries, Structure-Activity Relationship, medicine, Humans, Receptor, Integral membrane protein, G protein-coupled receptor, Dose-Response Relationship, Drug, Molecular Structure, Drug discovery, DNA-encoded chemical library, Chemistry, Receptors, Neurokinin-3, General Chemistry, General Medicine, DNA, Combinatorial chemistry, Small molecule, medicine.anatomical_structure, HEK293 Cells, Quinolines, Tachykinin receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662cc2aa88e33f6c57ffd2c4564e3e69Test
https://pubmed.ncbi.nlm.nih.gov/26562224Test -
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المؤلفون: Yosuf Yassin, Toshiyuki Araki, Benjamin G. Neel, Alex M. Tamburino, Kenneth D. Swanson, Amy E. Roberts, Kate Montgomery, Li Li, Taryn A. Schiripo, Raju Kucherlapati, Victoria A. Joshi
المصدر: Nature Genetics. 39:70-74
مصطلحات موضوعية: musculoskeletal diseases, Genetics, congenital, hereditary, and neonatal diseases and abnormalities, animal structures, biology, Son of Sevenless, medicine.disease, Cardiofaciocutaneous syndrome, LEOPARD Syndrome, PTPN11, Costello syndrome, SOS1, medicine, biology.protein, Noonan syndrome, skin and connective tissue diseases, Noonan Syndrome with Multiple Lentigines
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4bdbb5f3b21b90197917cbed80569c36Test
https://doi.org/10.1038/ng1926Test