دورية أكاديمية
A nationwide retrospective study in Turkish children with nephrocalcinosis
| العنوان: | A nationwide retrospective study in Turkish children with nephrocalcinosis |
|---|---|
| المؤلفون: | Nalcacıoğlu, Hülya, Döven, Serra Sürmeli, Tülpar, Sabahat, Baştuğ, Funda, Yıldırım, Zeynep Yürük, Karabağ, Esra Yılmaz, Çiçek, Neslihan, Küçük, Nuran, Çomak, Elif, Yazıcıoğlu, Burcu, Delibaş, Ali, Uysal, Berfin, Ağbaş, Ayşe, Gemici, Atilla, Günay, Neslihan, Ertan, Pelin, Bıyıklı, Neşe, Hacıhamdioğlu, Duygu Övünç, Elmacı, Ahmet Midhat, Delebe, Emine Özlem Çam, Atikel, Yeşim Özdemir, Sever, Lale, Gökçe, İbrahim, Öner, Nimet, Akman, Sema, Aksu, Bağdegül, Atmış, Bahriye, Yel, Sibel, Yılmaz, Alev, Çelik, Binnaz, Dursun, İsmail, Alpay, Harika |
| المساهمون: | OMÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, orcid:0000-0002-0686-9714, Nalcacıoğlu, Hülya |
| بيانات النشر: | TÜBİTAK |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | bartter syndrome, hypercalciuria, nephrocalcinosis, renal tubular acidosis |
| الوصف: | Tam Metin / Full Text ; Q4 ; PMID: 34174796 ; WOS:000724833600003 ; SCI-Expanded ; Nephrocalcinosis (NC) is defined as calcium deposition in the kidney parenchyma and tubules. This study aims to determine the etiology, risk factors, and follow-up results of patients with NC in Turkey. Materials and methods: Patients diagnosed with NC in the pediatric nephrology Department Units of 19 centers from all geographical regions of Turkey over a 10-year period (2010–2019) were included in the study. The medical records from the centers were reviewed and demographic data, admission complaints, medical history, systemic and genetic disorders, risk factors for NC, treatment details, and presence of NC after one-year follow-up, were recorded retrospectively. Results: The study sample included 195 patients (88 females, 107 males). The mean age at diagnosis was 39.44 ± 47.25 (0.5–208) months; 82/190 patients (43.2%) were diagnosed incidentally; 46/195 patients (23.6%) had an underlying disease; idiopathic hypercalciuria was detected in 75/195 (38.4%) patients. The most common systemic diseases were distal renal tubular acidosis in 11/46 patients (23.9%), primary hyperoxaluria in 9/46 patients (19.6%) and Bartter syndrome in 7/46 patients (15.3%). After one year of follow-up, NC resolved in 56/159 patients (35.2%) and they all did not have an underlying systemic disease. Conclusion: The most common presentation of NC was incidental. Distal renal tubular acidosis and primary hyperoxaluria were the main systemic diseases leading to NC, while hypercalciuria was the most common metabolic risk factor. Nephrocalcinosis was found to remain in most of the patients at a one-year follow-up. It may resolve particularly in patients with no underlying systemic disease. Keywords: Bartter syndrome, hypercalciuria, nephrocalcinosis, renal tubular acidosis |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Turkish Journal of Medical Sciences; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; DÖVEN S. S,TÜLPAR S,BAŞTUĞ F,YILDIRIM Z. Y,YILMAZ E. K,ÇİÇEK N,KÜÇÜK N,ÇOMAK E,YAZICIOĞLU B,NALCACIOĞLU H,DELİBAŞ A,UYSAL B,AĞBAŞ A,GEMİCİ A,GÜNAY N,ERTAN P,BIYIKLI N,HACIHAMDİOĞLU D. Ö,ELMACI A. M,ATİKEL Y. Ö,DELEBE E. Ö. Ç,SEVER L,GOKCE I,ÖNER N,AKMAN S,AKSU B,ATMIŞ B,YEL S,YILMAZ A,ÇELİK B,DURSUN İ,ALPAY H (2021). A nationwide retrospective study in Turkish children with nephrocalcinosis. Turkish Journal of Medical Sciences, 51(5), 2564 - 2569. Doi:10.3906/sag-2103-347; 1300-0144 / 1303-6165; https://doi.org/10.3906/sag-2103-347Test; https://hdl.handle.net/20.500.12712/33093Test; https://pubmed.ncbi.nlm.nih.gov/34174796Test/; 51; 2564; 2569 |
| DOI: | 10.3906/sag-2103-347 |
| الإتاحة: | https://doi.org/20.500.12712/33093Test https://doi.org/10.3906/sag-2103-347Test https://hdl.handle.net/20.500.12712/33093Test https://pubmed.ncbi.nlm.nih.gov/34174796Test/ |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.C2F34DEB |
| قاعدة البيانات: | BASE |
| DOI: | 10.3906/sag-2103-347 |
|---|