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1دورية أكاديمية
المؤلفون: Mark S. Moehle (11217998), Aaron M. Bender (5155397), Jonathan W. Dickerson (3628004), Daniel J. Foster (4760043), Aidong Qi (2204728), Hyekyung P. Cho (59088), Yuping Donsante (11218001), Weimin Peng (2649190), Zoey Bryant (11218004), Kaylee J. Stillwell (11218007), Thomas M. Bridges (1336731), Sichen Chang (1475053), Katherine J. Watson (11218010), Jordan C. O’Neill (3778144), Julie L. Engers (1475044), Li Peng (83452), Alice L. Rodriguez (1270236), Colleen M. Niswender (353419), Craig W. Lindsley (203380), Ellen J. Hess (11218013), P. Jeffrey Conn (1270239), Jerri M. Rook (1315593)
مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Molecular Biology, Neuroscience, Pharmacology, Evolutionary Biology, Cancer, Science Policy, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, nonselective mAChR antagonists, mAChR knockout animals, M 4 receptor activation, subtype, movement disorders, nonselective antimuscarinic therape., muscarinic acetylcholine receptors, M 4 Muscarinic Acetylcholine Recept., M 4, antiparkinsonian, M 4 muscarinic acetylcholine receptor, role, VU, antidystonic efficacy, Antidystonic Efficacy Nonselective ., model
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2دورية أكاديمية
المؤلفون: Matthew Spock (11219123), Trever R. Carter (11219126), Katrina A. Bollinger (4375849), Changho Han (1309563), Logan A. Baker (11219129), Alice L. Rodriguez (1270236), Li Peng (83452), Jonathan W. Dickerson (3628004), Aidong Qi (2204728), Jerri M. Rook (1315593), Jordan C. O’Neill (3778144), Katherine J. Watson (11218010), Sichen Chang (1475053), Thomas M. Bridges (1336731), Julie L. Engers (1475044), Darren W. Engers (655505), Colleen M. Niswender (353419), P. Jeffrey Conn (1270239), Craig W. Lindsley (203380), Aaron M. Bender (5155397)
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Evolutionary Biology, Sociology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, novel use, DMPK properties, movement disorders, Orally Bioavailable M 4 Muscarinic ., CYP inhibition, deuterium incorporation, SAR, M 4 mAChR antagonist, VU 6028418
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المؤلفون: Sichen Chang, Jonathan W. Dickerson, Baker Logan A, Thomas M. Bridges, Craig W. Lindsley, Darren W. Engers, Aidong Qi, Jerri M. Rook, Aaron M. Bender, P. Jeffrey Conn, Katrina A. Bollinger, Colleen M. Niswender, Changho Han, Alice L. Rodriguez, Trever R Carter, Li Peng, Julie L. Engers, Jordan C. O’Neill, Matthew Spock, Katherine J. Watson
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Dystonia, Movement disorders, Chemistry, Organic Chemistry, Antagonist, Pharmacology, medicine.disease, Highly selective, Biochemistry, In vitro, Bioavailability, In vivo, Drug Discovery, Muscarinic acetylcholine receptor, medicine, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388290e5061b99e6a85f95357b9a3b32Test
https://doi.org/10.1021/acsmedchemlett.1c00363Test -
4
المؤلفون: Jerri M. Rook, Aaron M. Bender, Colleen M. Niswender, Yuping Donsante, P. Jeffrey Conn, Hyekyung P. Cho, Li Peng, Julie L. Engers, Jonathan W. Dickerson, Thomas M. Bridges, Craig W. Lindsley, Ellen J. Hess, Sichen Chang, Aidong Qi, Weimin Peng, Mark S. Moehle, Jordan C. O’Neill, Daniel J. Foster, Alice L. Rodriguez, Zoey Bryant, Katherine J. Watson, Kaylee J. Stillwell
المصدر: ACS Pharmacology & Translational Science. 4:1306-1321
مصطلحات موضوعية: Pharmacology, Dystonia, Movement disorders, business.industry, Central nervous system, medicine.disease, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Tolerability, In vivo, Muscarinic acetylcholine receptor, Genetic model, Medicine, Pharmacology (medical), medicine.symptom, business, Neurotransmitter
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f5425dfe0a6fb74da410878130ec6660Test
https://doi.org/10.1021/acsptsci.0c00162Test -
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المؤلفون: Aaron M, Bender, Trever R, Carter, Matthew, Spock, Alice L, Rodriguez, Jonathan W, Dickerson, Jerri M, Rook, Sichen, Chang, Aidong, Qi, Christopher C, Presley, Darren W, Engers, Joel M, Harp, Thomas M, Bridges, Colleen M, Niswender, P Jeffrey, Conn, Craig W, Lindsley
المصدر: Bioorganicmedicinal chemistry letters. 56
مصطلحات موضوعية: Structure-Activity Relationship, Dose-Response Relationship, Drug, Molecular Structure, Receptor, Muscarinic M4, Humans, Muscarinic Antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::15d71c45fc9259c6cf1b62b08759c9b1Test
https://pubmed.ncbi.nlm.nih.gov/34838649Test -
6دورية أكاديمية
المؤلفون: Zhannan Wang, Yingkai He, Wenfeng Wang, Yawen Tian, Chongbo Ge, Futing Jia, Tongyu Zhang, Gerui Zhang, Mingyue Wang, Jinshuo Gong, Haibin Huang, Jianzhong Wang, Chunwei Shi, Wentao Yang, Xin Cao, Yan Zeng, Nan Wang, Aidong Qian, Yanlong Jiang, Guilian Yang, Chunfeng Wang
المصدر: Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-25 (2023)
مصطلحات موضوعية: Influenza virus, Nanoparticle vaccine, DC targeting, Sequential immunization, TRM cell, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1477-3155Test
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7
المؤلفون: Mark S, Moehle, Aaron M, Bender, Jonathan W, Dickerson, Daniel J, Foster, Aidong, Qi, Hyekyung P, Cho, Yuping, Donsante, Weimin, Peng, Zoey, Bryant, Kaylee J, Stillwell, Thomas M, Bridges, Sichen, Chang, Katherine J, Watson, Jordan C, O'Neill, Julie L, Engers, Li, Peng, Alice L, Rodriguez, Colleen M, Niswender, Craig W, Lindsley, Ellen J, Hess, P Jeffrey, Conn, Jerri M, Rook
المصدر: ACS Pharmacol Transl Sci
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::201a9605778eafcb97e04614395cae35Test
https://pubmed.ncbi.nlm.nih.gov/34423268Test -
8
المؤلفون: Jerri M. Rook, P. Jeffrey Conn, Aidong Qi, Aaron M. Bender, Matthew Spock, Colleen M. Niswender, Thomas M. Bridges, Sichen Chang, Trever R Carter, Craig W. Lindsley, Joel M. Harp, Christopher C Presley, Alice L. Rodriguez, Darren W. Engers, Jonathan W. Dickerson
المصدر: Bioorganic & Medicinal Chemistry Letters. 56:128479
مصطلحات موضوعية: Early generation, biology, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Cytochrome P450, Multiple species, Biochemistry, Drug Discovery, Aqueous solubility, Muscarinic acetylcholine receptor, biology.protein, Molecular Medicine, Potency, Enantiomer, Selectivity, Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8e9bcf50b4cdb04cbbd84852b4ecd42fTest
https://doi.org/10.1016/j.bmcl.2021.128479Test -
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المؤلفون: Ping Wang, Susan H. Guttentag, Shufang Meng, Seunghyi Kook, Peter M. Gulleman, Aidong Qi, Lisa R. Young
المصدر: American Journal of Respiratory Cell and Molecular Biology. 58:566-574
مصطلحات موضوعية: Genetic Markers, 0301 basic medicine, Pulmonary and Respiratory Medicine, Clinical Biochemistry, Mice, Transgenic, Biology, Lamellar granule, medicine.disease_cause, Cell Line, 03 medical and health sciences, CRISPR-Associated Protein 9, Protein targeting, medicine, Animals, Humans, Macrophage, Clustered Regularly Interspaced Short Palindromic Repeats, Genetic Predisposition to Disease, Molecular Biology, Gene, Gene Editing, Mutation, Cell Biology, respiratory system, medicine.disease, Phenotype, eye diseases, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, Major Technical Advances, 030104 developmental biology, Hermanski-Pudlak Syndrome, Cell culture, Alveolar Epithelial Cells, CRISPR-Cas Systems, Hermansky–Pudlak syndrome
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0709820b4ddcc0f8b4b21e7d9bc0c729Test
https://doi.org/10.1165/rcmb.2017-0324maTest -
10
المؤلفون: Galina I. Lepesheva, F. Peter Guengerich, Tatiana Y. Hargrove, Zdzislaw Wawrzak, Robert J. Schotzinger, William J. Hoekstra, John D. York, Laura Friggeri, Aidong Qi
المصدر: Journal of Biological Chemistry. 292:6728-6743
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Posaconazole, biology, Candida glabrata, Itraconazole, 030106 microbiology, Cell Biology, Pharmacology, biology.organism_classification, Biochemistry, Microbiology, 03 medical and health sciences, 030104 developmental biology, chemistry, Candida krusei, medicine, Azole, Ketoconazole, Candida albicans, Molecular Biology, Fluconazole, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1ecddb095b33c10a5e57cdb61c5c01cdTest
https://doi.org/10.1074/jbc.m117.778308Test