نتائج البحث - "Aichinger, Georg"

1

دورية أكاديمية

Physiologically based kinetic (PBK) modeling as a new approach methodology (NAM) for predicting systemic levels of gut microbial metabolites

المؤلفون: Stevanoska, Maja, Folz, Jacob, id_orcid:0 000-0001-5763-2963, Beekmann, Karsten, Aichinger, Georg, id_orcid:0 000-0003-1691-7609

المصدر: Toxicology Letters, 396

مصطلحات موضوعية: Biotransformation, Kinetic modeling, New approach methodologies, Gut microbial metabolism, Ex vivo/in vitro models, Gut microbiome

وصف الملف: application/application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/wos/001239941800001; info:eu-repo/grantAgreement/SBFI/HE/101057014/22.00417; http://hdl.handle.net/20.500.11850/672338Test

الإتاحة: https://doi.org/20.500.11850/67233810.3929/ethz-b-00067233810.1016/j.toxlet.2024.04.013Test
https://hdl.handle.net/20.500.11850/672338Test

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2

دورية أكاديمية

Baricitinib and tofacitinib off-target profile, with a focus on Alzheimer's disease

المؤلفون: Faquetti, Maria L., Slappendel, Laura, Bigonne, Hélène, Grisoni, Francesca, Schneider, Petra, Aichinger, Georg, Schneider, Gisbert, Sturla, Shana J., Burden, Andrea M.

المصدر: Faquetti , M L , Slappendel , L , Bigonne , H , Grisoni , F , Schneider , P , Aichinger , G , Schneider , G , Sturla , S J & Burden , A M 2024 , ' Baricitinib and tofacitinib off-target profile, with a focus on Alzheimer's disease ' , Alzheimer's and Dementia: Translational Research & Clinical Interventions , vol. 10 , no. 1 , e12445 . https://doi.org/10.1002/trc2.12445Test

مصطلحات موضوعية: Alzheimer's disease, Janus kinase inhibitors, machine learning, off-target, physiological based pharmacokinetic modeling, target prediction, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://research.tue.nl/en/publications/85d72640-2c5b-470a-afd4-f9dbdfa1874eTest

الإتاحة: https://doi.org/10.1002/trc2.12445Test
https://research.tue.nl/en/publications/85d72640-2c5b-470a-afd4-f9dbdfa1874eTest
https://pure.tue.nl/ws/files/318470618/A_D_Transl_Res_Clin_Interv_-_2024_-_Faquetti_-_Baricitinib_and_tofacitinib_off_target_profile_with_a_focus_on_Alzheimer.pdfTest
http://www.scopus.com/inward/record.url?scp=85183420999&partnerID=8YFLogxKTest

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3

دورية أكاديمية

Physiologically-Based Pharmacokinetic Modeling of the Postbiotic Supplement Urolithin A Predicts its Bioavailability Is Orders of Magnitude Lower than Concentrations that Induce Toxicity, but also Neuroprotective Effects

المؤلفون: Aichinger, Georg, Stevanoska, Maja, Beekmann, Karsten, Sturla, Shana J.

المصدر: Molecular Nutrition and Food Research 67 (2023) 15 ; ISSN: 1613-4125

مصطلحات موضوعية: ADME, PBPK, QIVIVE, nutraceutical, polyphenol

وصف الملف: application/pdf

العلاقة: https://edepot.wur.nl/635692Test; https://research.wur.nl/en/publications/physiologically-based-pharmacokinetic-modeling-of-the-postbioticTest-

الإتاحة: https://doi.org/10.1002/mnfr.202300009Test
https://research.wur.nl/en/publications/physiologically-based-pharmacokinetic-modeling-of-the-postbioticTest-

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4

دورية أكاديمية

New hemisynthetic derivatives of sphaeropsidin phytotoxins triggering severe endoplasmic reticulum swelling in cancer cells

المؤلفون: Ingels, Aude, Scott, Robert, Hooper, Annie R., van der Westhuyzen, Aletta E., Wagh, Sachin B., de Meester, Joséphine, Maddau, Lucia, Marko, Doris, Aichinger, Georg, Berger, Walter, Vermeersch, Marjorie, Pérez-Morga, David, Maslivetc, Vladimir A., Evidente, Antonio, van Otterlo, Willem A. L., Kornienko, Alexander, Mathieu, Véronique

المساهمون: Ingels, Aude, Scott, Robert, Hooper, Annie R., van der Westhuyzen, Aletta E., Wagh, Sachin B., de Meester, Joséphine, Maddau, Lucia, Marko, Dori, Aichinger, Georg, Berger, Walter, Vermeersch, Marjorie, Pérez-Morga, David, Maslivetc, Vladimir A., Evidente, Antonio, van Otterlo, Willem A. L., Kornienko, Alexander, Mathieu, Véronique

مصطلحات موضوعية: Cancer, Diterpene, ER stre, Endoplasmic reticulum swelling, Iso-pimarane, Natural product, Sphaeropsidin

العلاقة: volume:14; issue:1; journal:SCIENTIFIC REPORTS; https://hdl.handle.net/11388/336689Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85196804162

الإتاحة: https://doi.org/10.1038/s41598-024-65335-3Test
https://hdl.handle.net/11388/336689Test

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5

دورية أكاديمية

Persistence of the antagonistic effects of a natural mixture of Alternaria mycotoxins on the estrogen-like activity of human feces after anaerobic incubation

المؤلفون: Crudo, Francesco, Aichinger, Georg, Dellafiora, Luca, Kiss, Endre, Mihajlovic, Jovana, Del Favero, Giorgia, Berry, David, Dall'Asta, Chiara, Marko, Doris

المساهمون: Crudo, Francesco, Aichinger, Georg, Dellafiora, Luca, Kiss, Endre, Mihajlovic, Jovana, Del Favero, Giorgia, Berry, David, Dall'Asta, Chiara, Marko, Doris

مصطلحات موضوعية: Alternaria, Mycotoxin, estrogen receptor, food contaminant, mycoestrogen, tenuazonic acid

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000791560100010; volume:358; firstpage:88; lastpage:99; numberofpages:12; journal:TOXICOLOGY LETTERS; https://hdl.handle.net/11381/2915493Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85123958201

الإتاحة: https://doi.org/10.1016/j.toxlet.2022.01.015Test
https://hdl.handle.net/11381/2915493Test

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