دورية أكاديمية
Orexins cause epileptic activity
العنوان: | Orexins cause epileptic activity |
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المؤلفون: | Erken, Haydar Ali, Erken, Gülten, Gen, Osman, Kortunay, Selim, Ahiner, Melike, Turgut, Günfer, Turgut, Sebahat |
سنة النشر: | 2012 |
المجموعة: | Kütahya Dumlupınar University Institutional Repository |
مصطلحات موضوعية: | EEG, Epilepsy, Hypocretin, Orexin, Power spectrum, Seizure |
الوصف: | Orexins have been implicated in the regulation of sleep-wake cycle, energy homeostasis, drinking behavior, analgesia, attention, learning and memory but their effects on epileptic activity are controversial. We investigated whether intracortical injections of orexin A (100 pmol) and B (100 pmol) cause epileptic activity in rats. We observed epileptic seizure findings on these two groups rats. Orexin A and B also significantly increased total EEG power spectrum. Our findings indicate that orexins cause epileptic activity. © 2012 Elsevier Inc. ; This study was supported by Pamukkale University Research Fund . |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 0196-9781 |
العلاقة: | Peptides; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://dx.doi.org/10.1016/j.peptides.2012.06.012Test; https://hdl.handle.net/20.500.12438/5154Test; 37; 161; 164 |
DOI: | 10.1016/j.peptides.2012.06.012 |
الإتاحة: | https://doi.org/20.500.12438/5154Test https://doi.org/10.1016/j.peptides.2012.06.012Test https://hdl.handle.net/20.500.12438/5154Test |
حقوق: | info:eu-repo/semantics/closedAccess |
رقم الانضمام: | edsbas.EDAFCE89 |
قاعدة البيانات: | BASE |
تدمد: | 01969781 |
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DOI: | 10.1016/j.peptides.2012.06.012 |