التفاصيل البيبلوغرافية
العنوان:
Novel advances in biotransformation and bioactivation research – 2020 year in review
المؤلفون:
Khojasteh, S Cyrus , Argikar, Upendra A , Driscoll, James P , Heck, Carley JS , King, Lloyd , Jackson, Klarissa D , Jian, Wenying , Kalgutkar, Amit S , Miller, Grover P , Kramlinger, Valerie , Rietjens, Ivonne MCM , Teitelbaum, Aaron M , Wang, Kai , Wei, Cong , Johnson, Benjamin M , Shu, Yue-Zhong , Zhuo, Xiaoliang , Meanwell, Nicholas A , Cerny, Matthew A , Obach, R Scott , Sharma, Raman , Spracklin, Douglas K , Walker, Gregory S , Goracci, Laura , Desantis, Jenny , Valeri, Aurora , Castellani, Beatrice , Eleuteri, Michela , Cruciani, Gabriele , Lall, Manjinder S , Bassyouni, Asser , Bradow, James , Brown, Maria , Bundesmann, Mark , Chen, Jinshan , Ciszewski, Gregory , Hagen, Anne E , Hyek, Dennis , Jenkinson, Stephen , Liu, Bo , Pan, Senliang , Reilly, Usa , Sach, Neal , Smaltz, Daniel J , Starr, Jeremy , Wagenaar, Melissa , de Bruyn Kops, Christina , Sicho, Martin , Mazzolari, Angelica , Kirchmair, Johannes , Korprasertthaworn, Porntipa , Chau, Nuy , Nair, Pramod C , Rowland, Andrew , Miners, John O , Wrobleski, Stephen T , Moslin, Ryan , Lin, Shuqun , Zhang, Yanlei , Spergel, Steven , Kempson, James , Tokarski, John S , Strnad, Joann , Zupa-Fernandez, Adriana , Cheng, Lihong , Shuster, David , Gillooly, Kathleen , Yang, Xiaoxia , Heimrich, Elizabeth , McIntyre, Kim W , Chaudhry, Charu , Khan, Javed , Ruzanov, Max , Tredup, Jeffrey , Mulligan, Dawn , Xie, Dianlin , Sun, Huadong , Huang, Christine , D'Arienzo, Celia , Aranibar, Nelly , Chiney, Manoj , Chimalakonda, Anjaneya , Pitts, William J , Lombardo, Louis , Carter, Percy H , Burke, James R , Weinstein, David S , Li, Jing , Liu, Ju , Enders, Jennifer , Arciprete, Michael , Tran, Chris , Aluri, Krishna , Guan, Li-Hua , O'Shea, Jonathan , Bisbe, Anna , Charisse, Klaus , Zlatev, Ivan , Najarian, Diana , Xu, Yuanxin , Kim, Jaeah , El Zahar, Noha M , Bartlett, Michael G , Katyayan, Kishore , Yi, Ping , Monk, Scott , Cassidy, Kenneth , Takahashi, Ryan H , Grandner, Jessica M , Bobba, Sudheer , Liu, Yanzhou , Beroza, Paul , Zhang, Donglu , Ma, Shuguang , Post, Noah , Yu, Rosie , Greenlee, Sarah , Gaus, Hans , Hurh, Eunju , Matson, John , Wang, Yanfeng , Tajima, Yuya , Toyoda, Takeshi , Hirayama, Yuichiro , Matsushita, Kohei , Yamada, Takanori , Ogawa, Kumiko , Watanabe, Kenji , Takamura-Enya, Takeji , Totsuka, Yukari , Wakabayashi, Keiji , Miyoshi, Noriyuki , Zhang, Jiayin , Chan, Chi-Kong , Ham, Yat-Hing , Chan, Wan , Schleiff, Mary Alexandra , Flynn, Noah R , Payakachat, Sasin , Schleiff, Benjamin Mark , Pinson, Anna O , Province, Dennis W , Swamidass, S Joshua , Boysen, Gunnar , Nardone-White, Dasean T , Bissada, Jennifer E , Abouda, Arsany A , Zhang, Zhuming , Connolly, Peter J , Lim, Heng Keang , Pande, Vineet , Meerpoel, Lieven , Teleha, Christopher , Branch, Jonathan R , Ondrus, Janine , Hickson, Ian , Bush, Tammy , Luistro, Leopoldo , Packman, Kathryn , Bischoff, James R , Ibrahim, Salam , Parrett, Christopher , Chong, Yolanda , Gottardis, Marco M , Bignan, Gilles , Mulder, Teresa , Bobba, Sudder , Johnson, Kevin M , Wang, Wei , Zhang, Chenghong , Cai, Jingwei , Choo, Edna F , Crawford, James J , Landry, Matthew L , Chen, Huifen , Kenny, Jane R , Lee, Wendy , Young, Wendy B , Geib, Timon , Thulasingam, Madhuranayaki , Haeggstrom, Jesper Z , Sleno, Lekha , Monroe, James J , Tanis, Keith Q , Podtelezhnikov, Alexei A , Nguyen, Truyen , Machotka, Sam V , Lynch, Donna , Evers, Raymond , Palamanda, Jairam , Miller, Randy R , Pippert, Todd , Cabalu, Tamara D , Johnson, Timothy E , Aslamkhan, Amy G , Kang, Wen , Tamburino, Alex M , Mitra, Kaushik , Agrawal, Nancy GB , Sistare, Frank D
المصدر:
Drug Metabolism Reviews 53 (2021) 3
بيانات النشر:
Informa UK Limited, 2021.
سنة النشر:
2021
مصطلحات موضوعية:
METABOLISM , Toxicology , 030226 pharmacology & pharmacy , 03 medical and health sciences , nonp450 enzymes , 0302 clinical medicine , p450 enzymes , Biotransformation , INTRINSIC CLEARANCE , Political science , MASS-BALANCE , Humans , Pharmacology (medical) , Pharmacology & Pharmacy , P450 Enzymes , General Pharmacology, Toxicology and Pharmaceutics , ANTISENSE OLIGONUCLEOTIDE , Toxicologie , VLAG , ARISTOLOCHIC ACID , Drug metabolism , Science & Technology , WIMEK , bioactivation , IDENTIFICATION , Year in review , IN-VITRO , NONHEPATOTOXIC DRUGS , Drug metabolizing enzymes , Drug development , 030220 oncology & carcinogenesis , COVALENT BINDING DATA , Engineering ethics , biotransformation , LIVER-MICROSOMES , Life Sciences & Biomedicine
الوصف:
This annual review is the sixth of its kind since 2016 (see references). Our objective is to explore and share articles which we deem influential and significant in the field of biotransformation and bioactivation. These fields are constantly evolving with new molecular structures and discoveries of corresponding pathways for metabolism that impact relevant drug development with respect to efficacy and safety. Based on the selected articles, we created three sections: (1) drug design, (2) metabolites and drug metabolizing enzymes, and (3) bioactivation and safety (Table 1). Unlike in years past, more biotransformation experts have joined and contributed to this effort while striving to maintain a balance of authors from academic and industry settings.[Table: see text]. ispartof: DRUG METABOLISM REVIEWS vol:53 issue:3 pages:384-433 ispartof: location:England status: published
وصف الملف:
application/pdf; Print-Electronic
تدمد:
1097-9883
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a22a3073b1b8be7c5621703d8a65f67Test https://doi.org/10.1080/03602532.2021.1916028Test
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....9a22a3073b1b8be7c5621703d8a65f67
قاعدة البيانات:
OpenAIRE
