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1

دورية أكاديمية

MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

المؤلفون: Mikami Y., Philips R. L., Sciumè Giuseppe, Petermann F., Meylan F., Nagashima H., Yao C., Davis F. P., Brooks S. R., Sun H. -W., Takahashi H., Poholek A. C., Shih H. -Y., Afzali B., Muljo S. A., Hafner M., Kanno Y., O'Shea J. J.

المساهمون: Mikami, Y., Philips, R. L., Sciumè, Giuseppe, Petermann, F., Meylan, F., Nagashima, H., Yao, C., Davis, F. P., Brooks, S. R., Sun, H. -W., Takahashi, H., Poholek, A. C., Shih, H. -Y., Afzali, B., Muljo, S. A., Hafner, M., Kanno, Y., O'Shea, J. J.

مصطلحات موضوعية: helper T cell, IL23r, intestine, Maf, miR-221, miR-222, miRNA, mucosal barrier damage, negative feedback, Th17

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33657395; info:eu-repo/semantics/altIdentifier/wos/WOS:000627409300017; volume:54; issue:3; firstpage:514; lastpage:525.e6; numberofpages:19; journal:IMMUNITY; http://hdl.handle.net/11573/1533902Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85101966909

الإتاحة: https://doi.org/10.1016/j.immuni.2021.02.015Test
http://hdl.handle.net/11573/1533902Test

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2

دورية أكاديمية

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

المؤلفون: Kolev, M, West, EE, Kunz, N, Chauss, D, Moseman, EA, Rahman, J, Freiwald, T, Balmer, ML, Lotscher, J, Dimeloe, S, Rosser, EC, Wedderburn, LR, Mayer-Barber, KD, Bohrer, A, Lavender, P, Cope, A, Wang, L, Kaplan, MJ, Moutsopoulos, NM, McGavern, D, Holland, SM, Hess, C, Kazemian, M, Afzali, B, Kemper, C

المصدر: Immunity , 52 (3) 513-527.e8. (2020)

مصطلحات موضوعية: Intracellular complement, complosome, T cells, LFA-1, ICAM-1, integrins, metabolism, Th1 cells, lymphocyte adhesion deficiency type 1, LAD-1, biomarker

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10095008/3/Wedderburn_Kolev%20et%20al_Final%20LFA1_R2.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10095008Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10095008/3/Wedderburn_Kolev%20et%20al_Final%20LFA1_R2.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10095008Test/

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3

دورية أكاديمية

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

المؤلفون: Powell, N, Pantazi, E, Pavlidis, P, Tsakmaki, A, Li, K, Yang, F, Parker, A, Pin, C, Cozzetto, D, Minns, D, Stolarczyk, E, Saveljeva, S, Mohamed, R, Lavender, P, Afzali, B, Digby-Bell, J, Tjir-Li, T, Kaser, A, Friedman, J, MacDonald, TT, Bewick, GA, Lord, GM

وصف الملف: 578 - 590

العلاقة: GUT; https://qmro.qmul.ac.uk/xmlui/handle/123456789/68048Test

الإتاحة: https://doi.org/10.1136/gutjnl-2019-318483Test
https://qmro.qmul.ac.uk/xmlui/handle/123456789/68048Test

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4

دورية أكاديمية

HNRNPC haploinsufficiency affects alternative splicing of intellectual disability-associated genes and causes a neurodevelopmental disorder

المؤلفون: Niggl, E., Bouman, A., Briere, L.C., Hoogenboezem, R.M., Wallaard, I., Park, J., Admard, J., Wilke, M., Harris-Mostert, E.D.R.O., Elgersma, M., Bain, J., Balasubramanian, M., Banka, S., Benke, P.J., Bertrand, M., Blesson, A.E., Clayton-Smith, J., Ellingford, J.M., Gillentine, M.A., Goodloe, D.H., Haack, T.B., Jain, M., Krantz, I., Luu, S.M., McPheron, M., Muss, C.L., Raible, S.E., Robin, N.H., Spiller, M., Starling, S., Sweetser, D.A., Thiffault, I., Vetrini, F., Witt, D., Woods, E., Zhou, D., Elgersma, Y., van Esbroeck, A.C.M., Ambrose, J.C., Arumugam, P., Bevers, R., Bleda, M., Boardman-Pretty, F., Boustred, C.R., Brittain, H., Brown, M.A., Caulfield, M.J., Chan, G.C., Giess, A., Griffin, J.N., Hamblin, A., Henderson, S., Hubbard, T.J.P., Jackson, R., Jones, L.J., Kasperaviciute, D., Kayikci, M., Kousathanas, A., Lahnstein, L., Lakey, A., Leigh, S.E.A., Leong, I.U.S., Lopez, F.J., Maleady-Crowe, F., McEntagart, M., Minneci, F., Mitchell, J., Moutsianas, L., Mueller, M., Murugaesu, N., Need, A.C., O‘Donovan, P., Odhams, C.A., Patch, C., Perez-Gil, D., Pereira, M.B., Pullinger, J., Rahim, T., Rendon, A., Rogers, T., Savage, K., Sawant, K., Scott, R.H., Siddiq, A., Sieghart, A., Smith, S.C., Sosinsky, A., Stuckey, A., Tanguy, M., Taylor Tavares, A.L., Thomas, E.R.A., Thompson, S.R., Tucci, A., Welland, M.J., Williams, E., Witkowska, K., Wood, S.M., Zarowiecki, M., Acosta, M.T., Adams, D.R., Alvarez, R.L., Alvey, J., Allworth, A., Andrews, A., Ashley, E.A., Afzali, B., Bacino, C.A., Bademci, G., Balasubramanyam, A., Baldridge, D., Bale, J., Bamshad, M., Barbouth, D., Bayrak-Toydemir, P., Beck, A., Beggs, A.H., Behrens, E., Bejerano, G., Bellen, H.J., Bennet, J., Bernstein, J.A., Berry, G.T., Bican, A., Bivona, S., Blue, E., Bohnsack, J., Bonner, D., Botto, L., Brown, G., Burke, E.A., Burrage, L.C., Butte, M.J., Byers, P., Byrd, W.E., Carey, J., Carrasquillo, O., Cassini, T., Chang, T.C., Chanprasert, S., Chao, H.-T., Chinn, I., Clark, G.D., Coakley, T.R., Cobban, L.A., Cogan, J.D., Coggins, M., Cole, F.S., Colley, H.A., Cope, H., Corona, R., Craigen, W.J., Crouse, A.B., Cunningham, M., D'Souza, P., Dai, H., Dasari, S., Davis, J., Dayal, J.G., Delgado, M., Dell'Angelica, E.C., Dipple, K., Doherty, D., Dorrani, N., Doss, A.L., Douine, E.D., Earl, D., Eckstein, D.J., Emrick, L.T., Eng, C.M., Falk, M., Fieg, E.L., Fisher, P.G., Fogel, B.L., Forghani, I., Fu, J., Gahl, W.A., Glass, I., Goddard, P.C., Godfrey, R.A., Grajewski, A., Halley, M.C., Hamid, R., Hanchard, N., Hassey, K., Hayes, N., High, F., Hing, A., Hisama, F.M., Holm, I.A., Hom, J., Horike-Pyne, M., Huang, A., Huang, Y., Hutchison, S., Introne, W., Isasi, R., Izumi, K., Jarvik, G.P., Jarvik, J., Jayadev, S., Jean-Marie, O., Jobanputra, V., Kaitryn, E., Ketkar, S., Kiley, D., Kilich, G., Kobren, S.N., Kohane, I.S., Kohler, J.N., Korrick, S., Krakow, D., Krasnewich, D.M., Kravets, E., Lalani, S.R., Lam, B., Lam, C., Lanpher, B.C., Lanza, I.R., LeBlanc, K., Lee, B.H., Levitt, R., Lewis, R.A., Liu, P., Liu, X.Z., Longo, N., Loo, S.K., Loscalzo, J., Maas, R.L., Macnamara, E.F., MacRae, C.A., Maduro, V.V., Maghiro, A., Mahoney, R., Malicdan, M.C., Mamounas, L.A., Manolio, T.A., Mao, R., Marom, R., Marth, G., Martin, B.A., Martin, M.G., Martínez-Agosto, J.A., Marwaha, S., McCauley, J., McConkie-Rosell, A., McCray, A.T., McGee, E., Might, M., Miller, D., Mirzaa, G., Morava, E., Moretti, P., Morimoto, M., Mulvihill, J.J., Nakano-Okuno, M., Nelson, S.F., Nieves-Rodriguez, S., Novacic, D., Oglesbee, D., Orengo, J.P., Pace, L., Pak, S., Pallais, J.C., Papp, J.C., Parker, N.H., Petcharet, L., Phillips, J.A., Posey, J.E., Potocki, L., Swerdzewski, B.N., Quinlan, A., Rao, D.A., Raper, A., Raskind, W., Renteria, G., Reuter, C., Rives, L., Robertson, A.K., Rodan, L.H., Rosenfeld, J.A., Rosenthal, E., Rossignol, F., Ruzhnikov, M., Sabaii, M., Sacco, R., Sampson, J.B., Saporta, M., Schaechter, J., Schedl, T., Schoch, K., Scott, D.A., Seto, E., Sharma, P., Shashi, V., Shelkowitz, E., Sheppeard, S., Shin, J., Silverman, E., Sinsheimer, J., Sisco, K., Smith, E., Smith, K., Solnica-Krezel, L., Solomon, B., Spillmann, R., Stergachis, A., Stoler, J., Sullivan, K., Sullivan, J., Sutton, S., Sybert, V., Tabor, H.K., Tan, Q.K.-G., Tan, A.L., Tarakad, A., Tekin, M., Telischi, F., Thorson, W., Tifft, C., Toro, C., Tran, A.A., Ungar, R.A., Urv, T.K., Vanderver, A., Velinder, M., Viskochil, D., Vogel, T.P., Wahl, C.E., Walker, M., Walley, N.M., Wambach, J., Wan, J., Wang, L.-K., Wangler, M.F., Ward, P.A., Wegner, D., Weisz, M., Wener, M., Wenger, T., Westerfield, M., Wheeler, M.T., Whitlock, J., Wolfe, L.A., Yamamoto, S., Zhang, Z., Zuchner, S.

العلاقة: Niggl, E. orcid.org/0000-0002-5654-8425 , Bouman, A., Briere, L.C. et al. (345 more authors) (2023) HNRNPC haploinsufficiency affects alternative splicing of intellectual disability-associated genes and causes a neurodevelopmental disorder. The American Journal of Human Genetics, 110 (8). pp. 1414-1435. ISSN 0002-9297

الإتاحة: https://eprints.whiterose.ac.uk/208871Test/

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5

دورية أكاديمية

Interleukin 22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

المؤلفون: Powell, N, Pantazi, E, Tsamaki, A, Pavlidis, P, Li, K, Yang, F, Parker, A, Pin, C, Cozzetto, D, Minns, DH, Stolarczyk, E, Savelijeva, S, Mohamed, R, Lavender, P, Afzali, B, Digby-Bell, J, Tsui, T, Kaser, A, Friedman, J, MacDonald, TT, Bewick, GA, Lord, GM

المساهمون: Wellcome Trust

المصدر: 490 ; 478

العلاقة: Gut; http://hdl.handle.net/10044/1/75217Test; WT101159

الإتاحة: https://doi.org/10.1136/gutjnl-2019-318483Test
http://hdl.handle.net/10044/1/75217Test

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6

دورية أكاديمية

Complement receptor CD46 co-stimulates optimal human CD8(+) T cell effector function via fatty acid metabolism

المؤلفون: Arbore, G, West, EE, Rahman, J, Le Friec, G, Niyonzima, N, Pirooznia, M, Tunc, I, Pavlidis, P, Powell, N, Li, Y, Liu, P, Servais, A, Couzi, L, Fremeaux-Bacchi, V, Placais, L, Ferraro, A, Walsh, PR, Kavanagh, D, Afzali, B, Lavender, P, Lachmann, HJ, Kemper, C

المصدر: Nature Communications , 9 , Article 4186. (2018)

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10060941/1/Arbore_s41467-018-06706-z.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10060941Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10060941/1/Arbore_s41467-018-06706-z.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10060941Test/

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7

تقرير

RNF144A shapes the hierarchy of cytokine signaling to provide protective immunity against influenza

المؤلفون: Afzali, B., Kim, S., West, E., Nova-Lamperti, E., Cheru, N., Nagashima, H., Yan, B., Freiwald, T., Merle, N., Chauss, D., Bijlmakers, M., Weitsman, G., Yu, Z., Jankovic, D., Mitra, S., Villarino, A., Kemper, C., Laurence, A., Kazemian, M., O'Shea, J.J., John, S.

المصدر: Afzali , B , Kim , S , West , E , Nova-Lamperti , E , Cheru , N , Nagashima , H , Yan , B , Freiwald , T , Merle , N , Chauss , D , Bijlmakers , M , Weitsman , G , Yu , Z , Jankovic , D , Mitra , S , Villarino , A , Kemper , C , Laurence , A , Kazemian , M , O'Shea , J J & John , S 2019 ' RNF144A shapes the hierarchy of cytokine signaling to provide protective immunity against influenza ....

مصطلحات موضوعية: RNF144A, T cells, IL-2, STAT5, E3 Ubiquitin Ligase, RAF1, ERK-MAPK, influenza, human, mouse

الإتاحة: https://doi.org/10.1101/782680Test
https://kclpure.kcl.ac.uk/portal/en/publications/rnf144a-shapes-the-hierarchy-of-cytokine-signaling-to-provide-protective-immunity-against-influenzaTest(f941be2e-9361-4b53-abff-bfdf86fea8aa).html

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8

دورية أكاديمية

Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells

المؤلفون: Scotta C., Fanelli G., Hoong S. J., Romano M., Lamperti E. N., Sukthankar M., Guggino G., Fazekasova H., Ratnasothy K., Becker P. D., Afzali B., Lechler R. I., Lombardi G.

المساهمون: Scotta C., Fanelli G., Hoong S.J., Romano M., Lamperti E.N., Sukthankar M., Guggino G., Fazekasova H., Ratnasothy K., Becker P.D., Afzali B., Lechler R.I., Lombardi G.

مصطلحات موضوعية: Animal, Cells, Cultured, Female, Gene Expression Regulation, Human, Immunosuppressive Agent, Interleukin-10, Male, Mice, Inbred BALB C, Knockout, Receptors, Chemokine, T-Lymphocytes, Regulatory, Adoptive Transfer, Settore MED/16 - Reumatologia

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26471483; info:eu-repo/semantics/altIdentifier/wos/WOS:000371220700024; volume:101; issue:1; firstpage:91; lastpage:100; numberofpages:10; journal:HAEMATOLOGICA; http://hdl.handle.net/10447/399898Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84952880456; http://www.haematologica.org/content/haematol/101/1/91.full.pdfTest

الإتاحة: https://doi.org/10.3324/haematol.2015.128934Test
http://hdl.handle.net/10447/399898Test
http://www.haematologica.org/content/haematol/101/1/91.full.pdfTest

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