In this cross-sectional study, we explored the relationship between loneliness and problematic mobile phone use among Chinese adolescents during the COVID-19 pandemic, considering the effects of escape motivation and self-control. We recruited 1034 adolescents (mean age 15.76 ± 1.20 years) from China. The results showed that loneliness was positively associated with escape motivation and adolescent problematic mobile phone use. Furthermore, when controlling for gender, escape motivation mediated the relationship between loneliness and problematic mobile phone use, and self-control moderated the relationship between escape motivation and problematic mobile phone use. Specifically, as self-control increased, escape motivation was less likely to induce problematic mobile phone use. Thus, loneliness and escape motivation may be factors that increase the risk of problematic mobile phone use, and self-control should be considered in prevention and intervention strategies aimed at attenuating adolescent problematic mobile phone use.
