Epidemiology and etiology of influenza-like-illness in households in Vietnam; it’s not all about the kids!
| العنوان: | Epidemiology and etiology of influenza-like-illness in households in Vietnam; it’s not all about the kids! |
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| المؤلفون: | H. Rogier van Doorn, Tran Nhu Duong, Juliet E. Bryant, Behzad Nadjm, Peter Horby, Le Nguyen Minh Hoa, Nguyen Le Khanh Hang, Le Quynh Mai, Heiman F. L. Wertheim, Pham Quang Thai, Diep N. Nguyen, Annette Fox, Dang Duc Anh |
| المصدر: | Journal of Clinical Virology Journal of Clinical Virology, 82, 126-32 Journal of Clinical Virology, 82, pp. 126-32 |
| بيانات النشر: | Elsevier BV, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, viruses, Virus diseases, Adeno, adenoviruses, ILI, influenza like illness, Boca, bocavirus, 0302 clinical medicine, Influenza-like-illness, PIV, parainfluenza viruses, Epidemiology, Medicine, 030212 general & internal medicine, Child, Respiratory Tract Infections, Aged, 80 and over, Family Characteristics, Reverse Transcriptase Polymerase Chain Reaction, Transmission (medicine), Corona, coronaviruses, Cohort, virus diseases, Middle Aged, 3. Good health, Infectious Diseases, Vietnam, Virus Diseases, Child, Preschool, Viruses, Female, Nasal Cavity, Adult, medicine.medical_specialty, Adolescent, Entero, enteroviruses, Developing country, Real-Time Polymerase Chain Reaction, Article, Household transmission, Young Adult, 03 medical and health sciences, MPV, human metapneumovirus, Virology, Environmental health, Humans, ARI, acute respiratory illness, Intensive care medicine, Aged, Family Health, Respiratory viruses, Influenza-like illness, business.industry, Family characteristics, Infant, Newborn, Infant, Active case finding, 030112 virology, respiratory tract diseases, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], Etiology, Pharynx, RSV, respiratory syncytial virus, Rhino, rhinoviruses, business, Multiplex Polymerase Chain Reaction, Inf, influenza virus |
| الوصف: | Highlights • Rhino, Influenza and Corona viruses caused ∼50% of ILI in Vietnam households. • There was no clear seasonality for ILI, or for individual viruses causing ILI. • Children did not contribute substantially to ILI burden or transmission. • Seasonality and the contribution of children were unlike temporal settings. • Seasonality and social factors may affect the involvement of children in ILI. Background Household studies provide opportunities to understand influenza-like-illness (ILI) transmission, but data from (sub)tropical developing countries are scarce. Objective To determine the viral etiology and epidemiology of ILI in households. Study design ILI was detected by active case finding amongst a cohort of 263 northern Vietnam households between 2008 and 2013. Health workers collected nose and throat swabs for virus detection by multiplex real-time RT-PCR. Results ILI was detected at least once in 219 (23.7%) of 945 household members. 271 (62.3%) of 435 nose/throat swabs were positive for at least one of the 15 viruses tested. Six viruses predominated amongst positive swabs: Rhinovirus (28%), Influenza virus (17%), Coronavirus (8%), Enterovirus (5%), Respiratory syncytial virus (3%), Metapneumovirus virus (2.5%) and Parainfluenza virus 3 (1.8%). There was no clear seasonality, but 78% of episodes occurred in Winter/Spring for Influenza compared to 32% for Rhinovirus. Participants, on average, suffered 0.49 ILI, and 0.29 virus-positive ILI episodes, with no significant effects of gender, age, or household size. In contrast to US and Australian community studies, the frequency of ILI decreased as the number of household members aged below 5 years increased (p = 0.006). Conclusion The findings indicate the need for tailored ILI control strategies, and for better understanding of how local childcare practices and seasonality may influence transmission and the role of children. |
| وصف الملف: | application/pdf |
| تدمد: | 1386-6532 |
| DOI: | 10.1016/j.jcv.2016.07.014 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabe12a4fb0b8d79264aac4f7917c46dTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....dabe12a4fb0b8d79264aac4f7917c46d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13866532 |
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| DOI: | 10.1016/j.jcv.2016.07.014 |