المؤلفون: Ginny G. Farías, Juan A. Godoy, Félix Hernández, Jesús Avila, Abraham Fisher, Nibaldo C. Inestrosa

المصدر: Neurobiology of Disease, Vol 17, Iss 2, Pp 337-348 (2004)

مصطلحات موضوعية: M1 mAChR, Aβ neurotoxicity, GSK-3β transgenic mice, Wnt Signaling, Alzheimer's disease, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0969996104001536Test; https://doaj.org/toc/1095-953XTest

الوصول الحر: https://doaj.org/article/200d5f7b1eab430e853d5a6c92815ceaTest

المؤلفون: Abraham Fisher

المصدر: The Japanese Journal of Pharmacology. 2000, 84(2):101

المؤلفون: Ezio Giacobini, A Claudio Cuello, Abraham Fisher

المصدر: Brain. 145:2250-2275

مصطلحات موضوعية: Alzheimer Disease, Receptor, Muscarinic M1, Acetylcholinesterase, Cholinergic Agents, Humans, Cholinesterase Inhibitors, Neurology (clinical)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1cc080697decd093cb19cecffc5597Test
https://doi.org/10.1093/brain/awac096Test

المؤلفون: A.C. Cuello, Maria Florencia Iulita, Palma Gubert, Adriana Ducatenzeiler, Abraham Fisher, Lisi Flores Aguilar, Hélène Hall

المصدر: Alzheimer'sdementia : the journal of the Alzheimer's Association. 14(6)

مصطلحات موضوعية: 0301 basic medicine, Agonist, Amyloid, Epidemiology, medicine.drug_class, Administration, Oral, Neuropathology, Pharmacology, 03 medical and health sciences, Cellular and Molecular Neuroscience, Amyloid beta-Protein Precursor, 0302 clinical medicine, Developmental Neuroscience, Alzheimer Disease, Muscarinic acetylcholine receptor, medicine, Animals, Receptors, sigma, Spiro Compounds, Receptor, Neuroinflammation, Sigma-1 receptor, business.industry, Health Policy, Brain, 3. Good health, Rats, Psychiatry and Mental health, Disease Models, Animal, 030104 developmental biology, Cholinergic, Thiazolidines, Neurology (clinical), Geriatrics and Gerontology, Rats, Transgenic, business, Cognition Disorders, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f13948f1f4e9df1216c1c0aff2ee16Test
https://pubmed.ncbi.nlm.nih.gov/29291374Test

المؤلفون: Maria Florencia Iulita, Hélène Hall, Abraham Fisher, A. Claudio Cuello, Adriana Ducatenzeiler

المصدر: Alzheimer's & Dementia. 12

مصطلحات موضوعية: Agonist, Sigma-1 receptor, Epidemiology, business.industry, medicine.drug_class, Health Policy, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M1, Pharmacology, Anti-inflammatory, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, Medicine, Neurology (clinical), Geriatrics and Gerontology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cc7094f221d15f2e7bd37a9e8b4b395dTest
https://doi.org/10.1016/j.jalz.2016.06.2102Test

المؤلفون: Niva Natan, Lili Wu, Victoria Nahum, Abraham Fisher, Eitan Gershonov, Nira Bar-Ner, Hanoch Elkon, Rodrigo Medeiros, Frank M. LaFerla, Ilya Bezprozvanny, Daniel A. Ryskamp, Rachel Brandeis

المصدر: Fisher, Abraham; Bezprozvanny, Ilya; Wu, Lili; Ryskamp, Daniel A; Bar-Ner, Nira; Natan, Niva; et al.(2016). AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease.. Neuro-degenerative diseases, 16(1-2), 95-110. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/0rm238hcTest

مصطلحات موضوعية: 0301 basic medicine, Male, drug effects, physiology [Avoidance Learning], Drug Evaluation, Preclinical, Morris water navigation task, chemistry, pharmacology [Thiazolidines], Pharmacology, Hippocampus, PC12 Cells, Rats, Sprague-Dawley, 0302 clinical medicine, Muscarinic acetylcholine receptor, Medicine and Health Sciences, Receptor, Nootropic Agents, Cerebral Cortex, Chemistry, Muscarinic acetylcholine receptor M1, agonists, metabolism [Receptors, sigma], drug therapy, metabolism, pathology [Alzheimer Disease], pathology [Cerebral Cortex], 3. Good health, Neurology, Thiazolidines, Female, Alzheimer's disease, pharmacology [Nootropic Agents], medicine.drug, Agonist, medicine.medical_specialty, Carbachol, medicine.drug_class, pharmacology [Spiro Compounds], Allosteric regulation, Mice, Transgenic, Article, 03 medical and health sciences, Allosteric Regulation, Alzheimer Disease, Internal medicine, physiology [Maze Learning], metabolism [Receptor, Muscarinic M1], medicine, Avoidance Learning, Animals, Humans, Receptors, sigma, Spiro Compounds, pathology [Synapses], Rats, Wistar, Maze Learning, pathology [Hippocampus], Receptor, Muscarinic M1, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Endocrinology, Synapses, Neurology (clinical), 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c808f1fecaeec6a83b471e4875eadfeTest
https://europepmc.org/articles/PMC4803577Test/

المؤلفون: Hans Jc Buiter, Abraham Fisher, Albert D. Windhorst, Robert C. Schuit, Adriaan A. Lammertsma, Josée E. Leysen

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 55:264-273

مصطلحات موضوعية: Agonist, Chemistry, medicine.drug_class, Organic Chemistry, Radiosynthesis, Muscarinic acetylcholine receptor M1, Pharmacology, Ligand (biochemistry), Biochemistry, Analytical Chemistry, Drug Discovery, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, Enzyme-linked receptor, medicine, Inverse agonist, Radiology, Nuclear Medicine and imaging, Spectroscopy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::60fff267de2ff38f338cf8281e156a6dTest
https://doi.org/10.1002/jlcr.2932Test

المؤلفون: Abraham Fisher

المصدر: Journal of Neurochemistry. 120:22-33

مصطلحات موضوعية: biology, Amyloid, Disease, medicine.disease, Biochemistry, Cellular and Molecular Neuroscience, Nicotinic agonist, Muscarinic acetylcholine receptor, biology.protein, Amyloid precursor protein, medicine, Dementia, Cholinergic, Psychology, Neuroscience, Cholinesterase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2692f4bef8133d3b0b68541db7c98320Test
https://doi.org/10.1111/j.1471-4159.2011.07507.xTest

المؤلفون: Antonella Caccamo, Frank M. LaFerla, Abraham Fisher

المصدر: Current Alzheimer Research. 6:112-117

مصطلحات موضوعية: biology, Receptor, Muscarinic M1, Disease, Muscarinic Agonists, Models, Biological, Symptomatic relief, Neurology, Alzheimer Disease, Muscarinic acetylcholine receptor, biology.protein, medicine, Animals, Humans, Cholinergic, Neurology (clinical), Cognitive decline, Receptor, Psychology, Neuroscience, Acetylcholine, Antipsychotic Agents, Signal Transduction, Cholinesterase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfcc843bced72a956e4a7424718dd80Test
https://doi.org/10.2174/156720509787602915Test

المؤلفون: Abraham Fisher

المصدر: Current Alzheimer Research. 4:577-580

مصطلحات موضوعية: MAPK/ERK pathway, Pathology, medicine.medical_specialty, Hippocampus, Context (language use), Muscarinic Agonists, Pharmacology, Cevimeline, Piperidines, Alzheimer Disease, mental disorders, Muscarinic acetylcholine receptor, Animals, Humans, Medicine, Spiro Compounds, business.industry, Receptor, Muscarinic M1, Neurotoxicity, medicine.disease, Thiazoles, Neurology, Cholinergic, Neurology (clinical), Alzheimer's disease, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f913423f0a5023e09a7d6bcf3dcb53Test
https://doi.org/10.2174/156720507783018163Test