دورية أكاديمية
Frequency and Risk Factors of Diabetic Ketoacidosis in a Specialized Children’s Hospital, Riyadh: A Cross-sectional Study
| العنوان: | Frequency and Risk Factors of Diabetic Ketoacidosis in a Specialized Children’s Hospital, Riyadh: A Cross-sectional Study |
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| المؤلفون: | Amir Babiker, Ghadeer L. Aljahdali, Mohammed K. Alsaeed, Abdulrahman F. Almunif, Mohamud S. Mohamud, Angham Al Mutair, Fahad Al Juraibah, Ibrahim Al Alwan |
| المصدر: | Oman Medical Journal, Vol 37, Iss 1, Pp e341-e341 (2022) |
| بيانات النشر: | Oman Medical Specialty Board, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | diabetic ketoacidosis, diabetes mellitus, type 1, risk factors, saudi arabia, Medicine |
| الوصف: | Objectives: Diabetic ketoacidosis (DKA) is a life-threatening complication and a leading cause of hospitalization in patients with type 1 diabetes mellitus (T1DM). We aimed to assess the risk factors of admissions of children with DKA in a specialized children’s hospital to reduce morbidity and inform appropriate prevention and intervention strategies. Methods: We conducted a retrospective review of all DKA admissions at King Abdullah Specialized Children’s Hospital, Riyadh (March 2015–December 2017). Data were gathered from newly diagnosed patients with T1DM and known patients ≤ 14 years old with DKA criteria. The main variables were frequency, precipitating factors, and other characteristics of DKA admissions in both groups. Results: A total of 116/562 patients with T1DM (mean age 8.9±3.0 years) had 146 DKA episodes, of which 42/116 (36.2%) were newly diagnosed. The frequency of DKA admissions were 146/562 (26.0%), of which 42/141 (29.8%) were newly diagnosed versus 104/421 (24.7%) known T1DM patients. The majority were 10–14 years old (p ≤ 0.001), and 77.8% were females. Missing insulin was the main cause of DKA (p =0.001) among known patients with T1DM. Recurrent episodes (n = 30/146, 20.5%) occurred in 15/116 patients and were more common in children ≥ 10 years of age (p =0.024). The mean length of stay was 2.6±2.0 days and increased with DKA severity (p =0.008). Conclusions: Most DKA episodes were in patients with known T1DM and missing insulin was the leading cause of DKA. In addition to awareness campaigns to prevent DKA as an initial presen tation, intervention strategies should also target high-risk groups of known patients of T1DM such as adolescents and patients with recurrent episodes. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1999-768X 2070-5204 |
| العلاقة: | https://omjournal.org/articleDetails.aspx?coType=1&aId=3083Test; https://doaj.org/toc/1999-768XTest; https://doaj.org/toc/2070-5204Test |
| DOI: | 10.5001/omj.2021.124 |
| الوصول الحر: | https://doaj.org/article/cd4f93daa1e04d14b7144399dd489e7dTest |
| رقم الانضمام: | edsdoj.4f93daa1e04d14b7144399dd489e7d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1999768X 20705204 |
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| DOI: | 10.5001/omj.2021.124 |