المؤلفون: Rabia Johnson, Ebrahim Samodien, Lawrence Mabasa, Johan Louw, Nireshni Chellan, Carmen Pheiffer, Melisse Erasmus

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 27, Iss, Pp 1-10 (2019)

مصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Antioxidant, SOCS-3, suppressor of cytokine signaling-3, medicine.medical_treatment, Metabolic disease, Review, Pharmacology, medicine.disease_cause, 0302 clinical medicine, IR, insulin resistance, 2. Zero hunger, chemistry.chemical_classification, Neurodegeneration, food and beverages, IKκB, inhibitor of nuclear factor kappa-B kinase subunit beta, Neural mitochondrial dysfunction, 3. Good health, TLR4, Toll Like Receptor 4, medicine.symptom, lcsh:Internal medicine, Longevity, Hypothalamus, 030209 endocrinology & metabolism, Inflammation, POMC, pro-opiomelanocortin, NRF2, nuclear factor (erythroid-derived 2)-like 2 factor, STAT-3, signal transducer and activator of transcription 3, ARC, arcuate nucleus, 03 medical and health sciences, ROS, reactive oxygen species, Nutraceutical, Metabolic Diseases, medicine, Animals, Humans, Obesity, lcsh:RC31-1245, BBB, blood-brain-barrier, Molecular Biology, Nutrition, Reactive oxygen species, business.industry, Polyphenols, Cell Biology, PPs, polyphenols, medicine.disease, Diet, Hypothalamic inflammation, 030104 developmental biology, GTE, green tea extract, Mitochondrial biogenesis, chemistry, Dietary Supplements, NFκB, nuclear factor kappa B, SFAs, saturated fatty acids, business, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6d98bcfc10148c74cc22deffc56547Test
https://doi.org/10.1016/j.molmet.2019.06.022Test

المؤلفون: Chakera, Ali J., Hurst, Paul S., Spyer, Gill, Ogunnowo-Bada, Emmanuel O., Marsh, William J., Riches, Christine H., Yueh, Chen-Yu, Markkula, S. Pauliina, Dalley, Jeffrey W., Cox, Roger D., Macdonald, Ian A., Amiel, Stephanie A., MacLeod, Kenneth M., Heisler, Lora K., Hattersley, Andrew T., Evans, Mark L.

المساهمون: Dalley, Jeffrey [0000-0002-2282-3660], Evans, Mark [0000-0001-8122-8987], Apollo - University of Cambridge Repository

المصدر: Molecular Metabolism, Vol 17, Iss, Pp 17-27 (2018)
Chakera, A J, Hurst, P S, Spyer, G, Ogunnowo-Bada, E O, Marsh, W J, Riches, C H, Yueh, C Y, Markkula, S P, Dalley, J W, Cox, R D, Macdonald, I A, Amiel, S A, MacLeod, K M, Heisler, L K, Hattersley, A T & Evans, M L 2018, ' Molecular reductions in glucokinase activity increase counter-regulatory responses to hypoglycemia in mice and humans with diabetes ', Molecular Metabolism . https://doi.org/10.1016/j.molmet.2018.08.001Test
Molecular Metabolism

مصطلحات موضوعية: Adult, Blood Glucose, Male, lcsh:Internal medicine, ARC, Arcuate nucleus, Epinephrine, β-cells, HET, Heterozygous, HOM, Homozygous, Mice, Hyperinsulinism, Insulin-Secreting Cells, Glucokinase, Diabetes Mellitus, Animals, Humans, Hypoglycemic Agents, Insulin, Insulin clamp, lcsh:RC31-1245, VMN, Ventromedial hypothalamus, GE, Glucose excited, Mice, Inbred BALB C, SF1, steroidogenic factor 1, Counter-regulation, GI, Glucose inhibited, STZ, Streptozotocin, Middle Aged, Glucagon, Hypoglycemia, GCK, Glucokinase, Disease Models, Animal, Glucose, Glucose Clamp Technique, Original Article, Female, Maturity onset diabetes of young (MODY), WT, Wild type

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3790757ba77e77647b9ef28458dabd9aTest
http://www.sciencedirect.com/science/article/pii/S2212877818307506Test

المؤلفون: Michael M. Swarbrick, Sylvia J. Gasparini, Mark S. Cooper, Holger Henneicke, Jingbao Li, Lauryn L. Cavanagh, Hong Zhou, Colette Fong-Yee, Markus J. Seibel, Elisabeth Karsten, Sarah Kim, Daphne Foong, Ruby C.Y. Lin, Joanne Thai

المصدر: Molecular Metabolism, Vol 42, Iss, Pp 101098-(2020)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Leptin, Aging, STAT3, signal transducer and activator of transcription 3, Glucose uptake, Mice, Obese, Appetite, Adipose tissue, Mice, 0302 clinical medicine, Glucocorticoid, Insulin, OCR, oxygen consumption rate, media_common, Osteoblast, Age Factors, Brain, Osteocyte, Thermogenesis, medicine.anatomical_structure, Adipose Tissue, Hypothalamus, Body Composition, GTT, glucose tolerance test, Female, Original Article, Signal Transduction, medicine.drug, medicine.medical_specialty, lcsh:Internal medicine, TH, tyrosine hydroxylase, media_common.quotation_subject, Mice, Transgenic, 030209 endocrinology & metabolism, Bone and Bones, ARC, arcuate nucleus, 03 medical and health sciences, Insulin resistance, 11β-HSD, 11β-hydroxy-steroid dehydrogenase, Internal medicine, medicine, Animals, Obesity, IGF-1, insulin-like growth factor 1, lcsh:RC31-1245, Glucocorticoids, Molecular Biology, ITT, insulin tolerance test, business.industry, Body Weight, Arcuate Nucleus of Hypothalamus, UCP1, uncoupling protein-1, Cell Biology, medicine.disease, Mice, Inbred C57BL, BAT, brown adipose tissue, Glucose, 030104 developmental biology, Endocrinology, Insulin Resistance, business, PVN, paraventricular nucleus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2601bf9b23b0ab2ba1c9168d567906Test
http://www.sciencedirect.com/science/article/pii/S2212877820301721Test

المؤلفون: Estefanía P. Bello, Ramiro Alsina, Viviana Florencia Bumaschny, María B. Tavella, Milagros Trotta, José Luis Ferran, Marcelo Rubinstein

المصدر: Molecular Metabolism, Vol 37, Iss, Pp 100985-(2020)
Molecular Metabolism
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: Leptin, Male, 0301 basic medicine, Pro-Opiomelanocortin, Gene Expression, Mice, Obese, Arc, Arcuate nucleus, Eating, Mice, chemistry.chemical_compound, GABA, 0302 clinical medicine, Dorsomedial hypothalamic nucleus, Glucose homeostasis, Neuropeptide Y, GABAergic Neurons, Neurotransmitter, Arcuate hypothalamic nucleus, GABA, Gamma-aminobutyric acid, GLU, Glutamate, POMC, Proopiomelanocortin, digestive, oral, and skin physiology, purl.org/becyt/ford/3.1 [https], NPY, Neuropeptide Y, Neuropeptide Y receptor, DORSOMEDIAL HYPOTHALAMIC NUCLEUS, OBESITY, GABAergic, purl.org/becyt/ford/3 [https], Female, Original Article, hormones, hormone substitutes, and hormone antagonists, medicine.drug, medicine.medical_specialty, endocrine system, lcsh:Internal medicine, Hypothalamus, TAM, Tamoxifen, 030209 endocrinology & metabolism, In situ hybridization, Energy balance, Biology, ARCUATE HYPOTHALAMIC NUCLEUS, PROOPIOMELANOCORTIN, 03 medical and health sciences, Proopiomelanocortin, Orexigenic, Internal medicine, medicine, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, Body Weight, ENERGY BALANCE, Arcuate Nucleus of Hypothalamus, Cell Biology, DMH, Dorsomedial hypothalamic nucleus, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, nervous system, PVH, Paraventricular hypothalamic nucleus, biology.protein, Energy Metabolism, LH, Lateral hypothalamic nucleus

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed00f6a11823c774341490a25507dc2Test
http://www.sciencedirect.com/science/article/pii/S2212877820300594Test

المؤلفون: Henrik Oster, Mareike Bernau, Steffen E. Storck, Claus U. Pietrzik, Riccardo Dore, Alessandro Di Spiezio, Elvira Sonia Sandin, Hendrik Lehnert, Olaf Jöhren, Helge Müller-Fielitz, Walter Mier, Markus Schwaninger

المصدر: Molecular Metabolism, Vol 8, Iss, Pp 13-22 (2018)
Molecular Metabolism

مصطلحات موضوعية: Male, 0301 basic medicine, Leptin, HFD, high-fat diet, Endothelial cells, White adipose tissue, CSF, cerebrospinal fluid, Mice, 0302 clinical medicine, CPP, conditioned place preference, BBB, blood–brain barrier, Cells, Cultured, media_common, digestive, oral, and skin physiology, i.p., intraperitoneal, medicine.anatomical_structure, LepR, Blood-Brain Barrier, Blood–brain barrier, Obesity, Reward, Median eminence, qPCR, quantitative polymerase chain reaction, Receptors, Leptin, Original Article, Choroid plexus, medicine.medical_specialty, lcsh:Internal medicine, media_common.quotation_subject, Hyperphagia, Biology, VTA, ventral tegmental area, BC, bottle choice test, Capillary Permeability, ARC, arcuate nucleus, 03 medical and health sciences, PBS, phosphate buffered saline, Internal medicine, medicine, Animals, lcsh:RC31-1245, Molecular Biology, Circumventricular organs, Blood-Nerve Barrier, Leptin receptor, NCD, normal chow diet, Appetite, Cell Biology, 030104 developmental biology, Endocrinology, LepR, leptin receptor, Choroid Plexus, BSA, bovine serum albumin, PFA, paraformaldehyde, 030217 neurology & neurosurgery, DAPI, 4′,6-diamidino-2-phenylindole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb44b93448048edc0c6f47f7d2037f7Test
http://www.sciencedirect.com/science/article/pii/S2212877817308621Test

المؤلفون: Dadak, Selma, Beall, Craig, Vlachaki Walker, Julia M., Soutar, Marc P.M., McCrimmon, Rory J., Ashford, Michael L.J.

المصدر: Neuroscience

مصطلحات موضوعية: endocrine system, Neuroscience(all), CPT1, carnitine palmitolytransferase-1, Hypothalamus, ACC, acetyl-CoA carboxylase, GE, glucose-excited, AMP-Activated Protein Kinases, AMP-PNP, 5′-adenylylimidodiphosphate, CSF, cerebrospinal fluid, Article, VMN, ventromedial nucleus, Cell Line, Membrane Potentials, ARC, arcuate nucleus, oleate, Mice, POMC, proopiomelanocortin, Adenosine Triphosphate, KATP Channels, Animals, fatty acid oxidation, Membrane Potential, Mitochondrial, Neurons, AMPK, adenosine 5′-monophophate-activated protein kinase, GI, glucose-inhibited, glucose sensing, Arcuate Nucleus of Hypothalamus, KATP, mitochondria, KATP, ATP-sensitive potassium channel, oleate, Glucose, UCP, uncoupling protein, hormones, hormone substitutes, and hormone antagonists, Oleic Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::043a44e3df356df15b12f001d010c97cTest

المؤلفون: Joshua P. Thaler, Rachael Fasnacht, Mauricio D. Dorfman, L.D. Shaffer, John D. Douglass

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 4, Pp 366-373 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, MBH, mediobasal hypothalamus, Energy homeostasis, Pomc, proopiomelanocortin, VMN, ventromedial nucleus, Mice, Gliosis, NF-κB, nuclear factor kappa B, RER, respiratory exchange ratio, Cells, Cultured, 2. Zero hunger, Bdnf, brain-derived neurotrophic factor, Cart, cocaine- and amphetamine-regulated transcript, TMX, tamoxifen, digestive, oral, and skin physiology, NF-kappa B, food and beverages, 3. Good health, I-kappa B Kinase, medicine.anatomical_structure, GTT, glucose tolerance test, LPS, lipopolysaccharide, Tumor necrosis factor alpha, medicine.symptom, hormones, hormone substitutes, and hormone antagonists, IHC, immunohistochemistry, Astrocyte, Signal Transduction, Ccl2, C–C motif chemokine ligand 2, lcsh:Internal medicine, medicine.medical_specialty, Hypothalamus, Inflammation, Il, interleukin, CCL2, Biology, Brief Communication, Diet, High-Fat, Cocaine and amphetamine regulated transcript, ir, immunoreactivity, GSIS, glucose-stimulated insulin secretion, 03 medical and health sciences, ARC, arcuate nucleus, Internal medicine, medicine, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, Agrp, Agouti-related peptide, ITT, insulin tolerance test, Npy, neuropeptide Y, Brain-derived neurotrophic factor, Iba1, ionized calcium binding adaptor molecule 1, Tnfa, tumor necrosis factor α, DMH, dorsomedial hypothalamus, GFAP, glial fibrillary acidic protein, nutritional and metabolic diseases, Cell Biology, DIO, diet-induced obesity, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Metabolism, Astrocytes, Agouti-related peptide, IKKβ, inhibitor of kappa B kinase beta

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7a654f63e74ce9688a8fb5b5462534Test
http://europepmc.org/articles/PMC5369266Test

المؤلفون: Deborah J. Clegg, Ammy M. Santiago, Vanessa H. Routh

المصدر: Molecular Metabolism, Vol 5, Iss 10, Pp 823-833 (2016)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, ER, estrogen receptor, AMP-activated kinase, Estrogen receptor, Energy homeostasis, AICAR, aminoimidazole-4-carboxamide-1-β-d-ribofuranoside, PVDF, polyvinylidene difluoride, 0302 clinical medicine, AMP-activated protein kinase, Glucose homeostasis, HRP, horse radish peroxidase, Arc (protein), GI, glucose-inhibited, IR, input resistance, VMN, ventromedial hypothalamic nucleus, NGS, non-glucose sensing, CC, compound C, Glucose excited neurons, 17βE, 17β-estradiol, Original Article, VL-VMN, ventrolateral VMN, medicine.medical_specialty, lcsh:Internal medicine, Vm, membrane potential, Glucose inhibited neurons, GE, glucose-excited, POMC, pro-opiomelanocortin, Biology, PHTPP, phenyltrifluoromethylpyrazolophenol, 03 medical and health sciences, Sexual dimorphism, ARC, arcuate nucleus, Arcuate nucleus, Internal medicine, medicine, TTX, tetrodotoxin, lcsh:RC31-1245, Molecular Biology, VMH, ventromedial hypothalamus, 17β-estradiol, Cell Biology, SF-1, steroidogenic factor, Electrophysiology, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, Ventromedial hypothalamic nucleus, biology.protein, MPP, methylphenolpyrazole, GABA, γ-aminobutyric acid, 030217 neurology & neurosurgery, BSA-17βE, bovine serum albumin-conjugated 17βE, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0792f1b078bdfb0a0b5d66dfb61d08faTest
http://www.sciencedirect.com/science/article/pii/S2212877816301168Test

المؤلفون: Miguel López

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 8, Iss C, Pp 211-213 (2018)

مصطلحات موضوعية: Leptin, endocrine system, lcsh:Internal medicine, Pro-Opiomelanocortin, PSNA, parasympathetic nerve activity, STAT3, signal transducer and activator of transcription 3, SNA, parasympathetic nerve activity, Autonomic regulation, POMC, proopiomelanocortin, HFD, high fat diet, Autonomic nervous system, Medicine, Autonomic Pathways, lcsh:RC31-1245, MC3/4R, melanocortin 3 or 4 receptor, Molecular Biology, GFP, green fluorescent protein, Melanocortins, Neurons, ICV, intracerebroventricular, PI3K, phosphatidylinositol-3 kinase, AgRP, agouti-related peptide, business.industry, digestive, oral, and skin physiology, Cardiovascular regulation, WAT, white adipose tissue, Cell Biology, ARC, arcuate nucleus of the hypothalamus, BAT, brown adipose tissue, nervous system, LepR, leptin receptor, Commentary, α–MSH, α–melanocyte-stimulating hormone, Original Article, Energy homeostasis, Melanocortin, business, GABA, γ-aminobutyric acid, PRV, pseudorabies virus, Neuroscience, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5a0a87f8237986496f3035956a7f14Test
http://europepmc.org/articles/PMC5985046Test

المؤلفون: Paul T. Pfluger, Sonja C. Schriever, Katrin Pfuhlmann, Luke Harrison

المصدر: Mol. Metab. 24, 149-155 (2019)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Male, Weight loss, HFD, high-fat diet, ARC, Arcuate nucleus, RG, reactive gliosis, Mice, 0302 clinical medicine, EX4, exendin-4, Gliosis, Glial fibrillary acidic protein, biology, Chemistry, NEFA, non-esterified fatty acid, Microfilament Proteins, Astrogliosis, medicine.anatomical_structure, Hypothalamus, Reactive Gliosis, Obesity, Astrocyte, Weight Loss, Inflammation, medicine.symptom, Iba1, ionized calcium-binding adapter molecule 1, Agonist, medicine.medical_specialty, medicine.drug_class, HC, diet switch, Calorie restriction, AgRP, agouti related neuropeptide, 030209 endocrinology & metabolism, Brief Communication, CNS, central nervous system, 03 medical and health sciences, POMC, proopiomelanocortin, Internal medicine, Glial Fibrillary Acidic Protein, medicine, CR, calorie restriction, Animals, Molecular Biology, Caloric Restriction, FA, fatty acid, Calcium-Binding Proteins, GFAP, glial fibrillary acidic protein, Arcuate Nucleus of Hypothalamus, Cell Biology, DIO, diet-induced obesity, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Astrocytes, biology.protein, Exenatide, Anti-Obesity Agents, Reactive gliosis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97e351f03c31308275630423c838c97Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=55847Test