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1دورية أكاديمية
المؤلفون: Creus, Edgar, FERNÁNDEZ RODRÍGUEZ, JUANA, Magallon-Lorenz, Miriam, Ortega Bertran, Sara, Navas-Rutete, Susana, Romagosa Pérez-Portabell, Cleofé, Silva, Tulio M.
المساهمون: Institut Català de la Salut, Creus-Bachiller E, Ortega-Bertran S Hereditary Cancer Program, Catalan Institute of Oncology, ICO-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain. Program in Molecular Mechanisms and Experimental Therapy in Oncology (Oncobell), IDIBELL, Hospitalet de Llobregat, Barcelona, Spain. Fernández-Rodríguez JF Hereditary Cancer Program, Catalan Institute of Oncology, ICO-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain. Program in Molecular Mechanisms and Experimental Therapy in Oncology (Oncobell), IDIBELL, Hospitalet de Llobregat, Barcelona, Spain. Mouse Lab, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Magallón-Lorenz M Hereditary Cancer Group, Germans Trias i Pujol Research Institute (IGTP), Barcelona, Spain. Navas-Rutete S Hereditary Cancer Program, Catalan Institute of Oncology, ICO-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain. Romagosa C, Silva TM Servei de d’Anatomia Patològica, Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus
المصدر: Scientia
مصطلحات موضوعية: Medicina personalitzada, Cultiu cel·lular, Nervis perifèrics - Tumors, Tumors de parts toves, DISEASES::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Nerve Tissue::Nerve Sheath Neoplasms, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Precision Medicine, ANATOMY::Body Regions::Transplants::Heterografts, ANATOMY::Cells::Cells, Cultured::Cell Line, ENFERMEDADES::neoplasias::neoplasias por tipo histológico::neoplasias de tejido nervioso::neoplasias de las vainas nerviosas, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::medicina de precisión, ANATOMÍA::regiones corporales::trasplantes::heteroinjertos, ANATOMÍA::células::células cultivadas::línea celular
وصف الملف: application/pdf
العلاقة: Molecular Oncology;18(4); https://doi.org/10.1002/1878-0261.13534Test; Creus-Bachiller E, Fernández-Rodríguez J, Magallón-Lorenz M, Ortega-Bertran S, Navas-Rutete S, Romagosa C, et al. Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: new patient-derived orthotopic xenografts, cell lines and tumor entities. Mol Oncol. 2024 Apr;18(4):895–917.; https://hdl.handle.net/11351/11308Test; 001087354800001
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2دورية أكاديمية
المؤلفون: Torrents, Sílvia, Escudero del Moral, Andrés, Codinach, Margarita, Rodríguez Gómez, Luciano, Querol, Sergio, Vives, Joaquim
المساهمون: Institut Català de la Salut, Torrents S, Codinach M, Rodríguez L, Querol S Banc de Sang i Teixits, Edifci Dr. Frederic Duran i Jordà, Barcelona, Spain. Grup de Recerca de Medicina Transfusional, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Escudero Del Moral A Banc de Sang i Teixits, Edifci Dr. Frederic Duran i Jordà, Barcelona, Spain. Vives J Banc de Sang i Teixits, Edifci Dr. Frederic Duran i Jordà, Barcelona, Spain. Grup de Recerca d’Enginyeria Tissular Musculoesquelètica, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain, Vall d'Hebron Barcelona Hospital Campus
المصدر: Scientia
مصطلحات موضوعية: Cèl·lules mare mesenquimàtiques, Cultiu cel·lular, Resposta immunitària - Regulació, ANATOMY::Cells::Cells::Stem Cells::Multipotent Stem Cells::Mesenchymal Stem Cells, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::In Vitro Techniques::Culture Techniques::Coculture Techniques, ANATOMY::Cells::Cells, Cultured, AND EQUIPMENT::Therapeutics::Biological Therapy::Immunomodulation, ANATOMÍA::células::células::células madre::células madre multipotentes::células madre mesenquimatosas, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::técnicas in vitro::técnicas de cultivo::técnicas de cocultivo, ANATOMÍA::células::células cultivadas, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapia biológica::inmunomodulación
وصف الملف: application/pdf
العلاقة: Immunologic Research;71; https://doi.org/10.1007/s12026-023-09385-1Test; info:eu-repo/grantAgreement/ES/PEICTI2021-2023/RD21%2F0017%2F0022; Torrents S, Escudero del Moral A, Codinach M, Rodríguez L, Querol S, Vives J. Optimized reagents for immunopotency assays on mesenchymal stromal cells for clinical use. Immunol Res. 2023 Oct;71:725–734.; https://hdl.handle.net/11351/10401Test; 000980448600001
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3دورية أكاديمية
المؤلفون: Botta, Cirino, Pérez Ruiz, Cristina, Larrayoz, Marta, Puig, Noemi, CEDENA, M TERESA, Termini , Rosalinda, Gironella, Mercedes
المساهمون: Institut Català de la Salut, Botta C Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy. Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), CCUN, Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC numbers CB16/12/00369, CB16/12/00489, Pamplona, Spain. Perez C, Larrayoz M, Termini R Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), CCUN, Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC numbers CB16/12/00369, CB16/12/00489, Pamplona, Spain. Puig N Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), Centro de Investigación del Cancer (IBMCC-USAL, CSIC), CIBER-ONC number CB16/12/00233, Salamanca, Spain. Cedena MT Hospital Universitario 12 de Octubre, CIBER-ONC number CB16/12/00369, Madrid, Spain. Gironella M Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus
المصدر: Scientia
مصطلحات موضوعية: Mieloma múltiple - Tractament, Medicaments immunosupressors - Ús terapèutic, Cèl·lules T, DISEASES::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Plasma Cell::Multiple Myeloma, Other subheadings::Other subheadings::Other subheadings::/drug therapy, ANATOMY::Cells::Cells, Cultured::Clone Cells, CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Immunosuppressive Agents, Other subheadings::Other subheadings::/therapeutic use, ENFERMEDADES::neoplasias::neoplasias por tipo histológico::neoplasias de células plasmáticas::mieloma múltiple, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, ANATOMÍA::células::células cultivadas::células clonales, COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::efectos fisiológicos de los fármacos::factores inmunitarios::inmunosupresores, Otros calificadores::Otros calificadores::/uso terapéutico
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
العلاقة: Nature Communications;14; https://doi.org/10.1038/s41467-023-41562-6Test; Botta C, Perez C, Larrayoz M, Puig N, Cedena MT, Termini R, et al. Large T cell clones expressing immune checkpoints increase during multiple myeloma evolution and predict treatment resistance. Nat Commun. 2023 Sep 20;14:5825.; https://hdl.handle.net/11351/10359Test
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4دورية أكاديمية
المؤلفون: Juliachs, Mercè, Pujals-Pruneda, Mireia, Meo-Evoli, Nathalie, Duran, Juan M, Parés, Mireia, Suñol, Anna, Mendez Fernández, Olga, Sánchez Pla, Alex, Canals Suris, Francesc, Bellio, Chiara, Zamora, Esther, Saura, Cristina, Villanueva Cardús, Josep
المساهمون: Institut Català de la Salut, Juliachs M, Pujals M, Bellio C, Meo-Evoli N, Duran JM, Parés M, Suñol A, Méndez O, Canals F Vall d’Hebron Institut of Oncology (VHIO), Barcelona, Spain. Zamora E, Saura C Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Sánchez-Pla A Genetics Microbiology and Statistics Department, Universitat de Barcelona, Barcelona, Spain. Unitat d'Estadística i Bioinformàtica, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Villanueva J Vall d’Hebron Institut of Oncology (VHIO), Barcelona, Spain. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain, Vall d'Hebron Barcelona Hospital Campus
المصدر: Scientia
مصطلحات موضوعية: Mama - Càncer - Tractament, Marcadors tumorals, Medicaments antineoplàstics - Ús terapèutic, DISEASES::Neoplasms::Neoplasms by Site::Breast Neoplasms, Other subheadings::Other subheadings::Other subheadings::/drug therapy, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Combined Modality Therapy::Neoadjuvant Therapy, ANATOMY::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor, CHEMICALS AND DRUGS::Biological Factors::Biomarkers::Biomarkers, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de la mama, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::tratamiento combinado::tratamiento neoadyuvante, ANATOMÍA::células::células cultivadas::línea celular::línea celular tumoral, COMPUESTOS QUÍMICOS Y DROGAS::factores biológicos::biomarcadores::marcadores tumorales
وصف الملف: application/pdf
العلاقة: Cancers;14(16); https://doi.org/10.3390/cancers14163858Test; Juliachs M, Pujals M, Bellio C, Meo-Evoli N, Duran JM, Zamora E, et al. Circulating SOD2 Is a Candidate Response Biomarker for Neoadjuvant Therapy in Breast Cancer. Cancers. 2022 Aug 10;14(16):3858.; https://hdl.handle.net/11351/9662Test; 000847022400001
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5دورية أكاديمية
المؤلفون: Fernández Montes, Ana, Elez Fernandez, Mª Elena, Vivancos Prellezo, Ana, Martínez, N., González, P., Covela, M.
المساهمون: Institut Català de la Salut, Fernández Montes A Medical Oncology Department, Complexo Hospitalario Universitario de Ourense, Ourense, Spain. Élez E Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Vivancos A Cancer Genomics Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Martínez N Medical Oncology Department, Hospital Universitario A Coruña, A Coruña, Spain. González P Medical Oncology Department, Hospital Universitario Álvaro Cunqueiro, Vigo, Spain. Covela M Medical Oncology Department, Hospital Universitario Lucus Augusti, Lugo, Spain, Vall d'Hebron Barcelona Hospital Campus
المصدر: Scientia
مصطلحات موضوعية: Còlon - Càncer, Recte - Càncer, Clonatge molecular, DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms, ANATOMY::Cells::Cells, Cultured::Clone Cells, PHENOMENA AND PROCESSES::Genetic Phenomena::Genetic Variation::Mutation, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales, ANATOMÍA::células::células cultivadas::células clonales, FENÓMENOS Y PROCESOS::fenómenos genéticos::variación genética::mutación
وصف الملف: application/pdf
العلاقة: Clinical and Translational Oncology;24; https://doi.org/10.1007/s12094-021-02767-7Test; Fernández Montes A, Élez E, Vivancos A, Martínez N, González P, Covela M, et al. Monitoring of RAS mutant clones in plasma of patients with RAS mutant metastatic colorectal cancer. Clin Transl Oncol. 2022 Jun;24:1209–14.; https://hdl.handle.net/11351/8037Test; 000740217300002
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6دورية أكاديمية
المؤلفون: Calucho Prim, Maite, Gartner Tizzano, Silvia, Barranco Bartolomé, Paula, Fernández Álvarez, Paula, García Pérez, Raquel, Tizzano Ferrari, Eduardo Fidel
المساهمون: Institut Català de la Salut, Calucho M, Barranco P, Fernández-Álvarez P, Tizzano EF Grup de Recerca en Medicina Genètica, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Genètica Clínica i Molecular, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Gartner S Unitat de Fibrosi Quística, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Pérez RG Universitat Autònoma de Barcelona, Bellaterra, Spain, Vall d'Hebron Barcelona Hospital Campus
المصدر: Scientia
مصطلحات موضوعية: Fibrosi quística - Fisiologia patològica, Cultiu cel·lular - Investigació, Fibrosi quística - Tractament, ANATOMY::Cells::Cells, Cultured::Spheroids, Cellular, Other subheadings::Other subheadings::Other subheadings::/metabolism, DISEASES::Respiratory Tract Diseases::Lung Diseases::Cystic Fibrosis, Other subheadings::Other subheadings::Other subheadings::/pathology, ANATOMÍA::células::células cultivadas::esferoides celulares, Otros calificadores::Otros calificadores::Otros calificadores::/metabolismo, ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::fibrosis quística, Otros calificadores::Otros calificadores::Otros calificadores::/patología
وصف الملف: application/pdf
العلاقة: Scientific Reports;11; https://doi.org/10.1038/s41598-021-94798-xTest; Calucho M, Gartner S, Barranco P, Fernández-Álvarez P, Pérez RG, Tizzano EF. Validation of nasospheroids to assay CFTR functionality and modulator responses in cystic fibrosis. Sci Rep. 2021 Jul 30;11:15511.; https://hdl.handle.net/11351/7252Test; 000683318500005
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7دورية أكاديمية
المؤلفون: Gorbatenko, Andrej, Søkilde, Rolf, Sorensen, Ester E., Newie, Inga, Persson, Helena, Morancho Armisen, Beatriz, Arribas López, Joaquin Vicente
المساهمون: Institut Català de la Salut, Gorbatenko A Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, 10029, USA. Søkilde R, Newie I, Persson H BioCare, Strategic Cancer Research Program, Lund, Sweden. Department of Clinical Sciences Lund, Oncology and Pathology, Faculty of Medicine, Lund University, Lund, Sweden. Sorensen EE Section for Cell Biology and Physiology, Department of Biology, Faculty of Science, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark. Morancho B Preclinical Research Program, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. CIBERONC. Arribas J Preclinical Research Program, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. CIBERONC. Departament de Bioquímica i de Biologia Molecular, Universitat Autònoma de Barcelona, Bellaterra, Spain. Institució Catalana de Recerca i Estudis Avançats, JA, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus
المصدر: Scientia
مصطلحات موضوعية: Mama - Càncer, Cèl·lules canceroses, DISEASES::Neoplasms::Neoplasms by Site::Breast Neoplasms, ANATOMY::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::MCF-7 Cells, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de la mama, ANATOMÍA::células::células cultivadas::línea celular::línea celular tumoral::células MCF-7
وصف الملف: application/pdf
العلاقة: Scientific Reports;9(1); https://www.nature.com/articles/s41598-019-39733-xTest; info:eu-repo/grantAgreement/ES/PE2013-2016/PI16%2F00253; Gorbatenko A, Søkilde R, Sorensen EE, Newie I, Persson H, Morancho B, et al. HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503. Sci Rep. 2019 Mar 4;9(1):3352.; https://hdl.handle.net/11351/5878Test; 000460123600024
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8
المؤلفون: Daniel Otero-Albiol, Sandra Muñoz-Galván, Eva M. Verdugo-Sivianes, Amancio Carnero, Ana M. Rojas
المساهمون: [Verdugo-Sivianes,EM, Muñoz-Galván,S, Otero-Albiol,D, Carnero,AS] Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocio, Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, Spain. [Verdugo-Sivianes,EM, Carnero,AS] CIBERONC, Instituto de Salud Carlos III, Madrid, Spain. [Rojas,AM] Centro Andaluz de Biología del Desarrollo (CABD), CSIC-Universidad Pablo de Olavide, Sevilla, Spain., This work was supported by grants from the Ministerio de Ciencia, Innovación y Universidades (MCIU) Plan Estatal de I+D+I 2018, a la Agencia Estatal de Investigación (AEI) y al Fondo Europeo de Desarrollo Regional (MCIU/AEI/FEDER, UE): RTI2018-097455-B-I00 and RTI2018-096735-B-I00grant from AEI-MICIU/FEDER (RED2018-102723-T), from CIBER de Cáncer (CB16/12/00275), co-funded by FEDER from Regional Development European Funds (European Union), from Consejeria de Salud (PI-0397-2017) and Consejeria of Economía, Conocimiento, Empresas y Universidad of the Junta de Andalucia (P18-RT-2501). Special thanks are also due to the Fundacion AECC and Fundacion Eugenio Rodriguez Pascual for supporting this work., Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Centro de Investigación Biomédica en Red Cáncer (España), Junta de Andalucía, Fundación Científica Asociación Española Contra el Cáncer, Fundación Eugenio Rodríguez Pascual
المصدر: Theranostics
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: 0301 basic medicine, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor [Medical Subject Headings], Proteína de retinoblastoma, Carcinogenesis, Mutant, Medicine (miscellaneous), Anatomy::Cells::Stem Cells::Neoplastic Stem Cells [Medical Subject Headings], medicine.disease_cause, environment and public health, Retinoblastoma Protein, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Mice, 0302 clinical medicine, Breast cancer, pRB, Anatomy::Cells::Cells, Cultured::Cell Line [Medical Subject Headings], stem cell phenotype, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nerve Tissue Proteins [Medical Subject Headings], Protein Phosphatase 1, Organisms::Eukaryota::Animals [Medical Subject Headings], Proteína fosfatasa 1, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Drug Evaluation, Preclinical::Drug Screening Assays, Antitumor::Xenograft Model Antitumor Assays [Medical Subject Headings], Phosphorylation, Phenomena and Processes::Metabolic Phenomena::Metabolism::Phosphorylation [Medical Subject Headings], Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle [Medical Subject Headings], Cell Line, Transformed, Mutation, Chemicals and Drugs::Macromolecular Substances::Polymers::Biopolymers::Microfilament Proteins [Medical Subject Headings], Retinoblastoma, Línea celular, Microfilament Proteins, Proteína 1 de unión a retinoblastoma, Cell cycle, Diseases::Neoplasms::Neoplastic Processes::Carcinogenesis [Medical Subject Headings], PP1, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints::G1 Phase Cell Cycle Checkpoints [Medical Subject Headings], Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins::Tumor Suppressor Protein p53 [Medical Subject Headings], Gene Expression Regulation, Neoplastic, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Transformed [Medical Subject Headings], Diseases::Neoplasms::Neoplasms by Site::Eye Neoplasms::Retinal Neoplasms [Medical Subject Headings], SPINOPHILIN, 030220 oncology & carcinogenesis, Neoplasias de la mama, Neoplastic Stem Cells, Cell lines, Female, biological phenomena, cell phenomena, and immunity, Research Paper, Signal Transduction, Carcinogénesis, cancer stem cell, animal structures, Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation [Medical Subject Headings], Stem cell phenotype, Mice, Nude, Breast Neoplasms, Nerve Tissue Proteins, macromolecular substances, Biology, Resting Phase, Cell Cycle, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins::Retinoblastoma Protein [Medical Subject Headings], Dephosphorylation, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Phosphoric Monoester Hydrolases::Phosphoprotein Phosphatases::Protein Phosphatase 1 [Medical Subject Headings], 03 medical and health sciences, Cancer stem cell, Cell Line, Tumor, medicine, Animals, Humans, Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms [Medical Subject Headings], Células madre neoplásicas, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice [Medical Subject Headings], Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Mutant Strains::Mice, Nude [Medical Subject Headings], pocket proteins, medicine.disease, G1 Phase Cell Cycle Checkpoints, Xenograft Model Antitumor Assays, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic [Medical Subject Headings], enzymes and coenzymes (carbohydrates), tumorigenesis, 030104 developmental biology, Check Tags::Female [Medical Subject Headings], Tumor progression, Cell culture, Retinoblastoma protein, Tumorigenesis, Cancer research, Tumor Suppressor Protein p53, Pocket proteins, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Holoenzymes [Medical Subject Headings]
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc94057a330544993a83e9fc556b68b2Test
http://europepmc.org/articles/PMC7847670Test -
9
المؤلفون: Matilde Ner, Juan A. Marchal, Yaiza Jiménez-Martínez, Joaquín M. Campos, Hugo Gutiérrez-de-Terán, Ana Conejo-García, Houria Boulaiz, Francho Nerín-Fonz, David Araripe, Olga Cruz-Lopez
المساهمون: [Cruz-López,O, Ner,M, Campos,JM, Conejo-García,A] Department of Medicinal and Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada, Spain. [Cruz-López,O, Jiménez-Martínez,Y, Marchal,JA, Boulaiz,H, Conejo-García,A] Biosanitary Institute of Granada (ibs.GRANADA), SAS-University of Granada, Granada, Spain. [Nerín-Fonz,F, Araripe,D, Gutiérrez-de-Terán,H] Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweeden. [Jiménez-Martínez,Y, Boulaiz,H] Biopathology and Medicine Regenerative Institute, University of Granada, Granada, Spain. [Jiménez-Martínez,Y, Boulaiz,H] Excellence Research Unit 'Modeling Nature' (MNat), Department of Human Anatomy and Embryology, University of Granada, Granada, Spain., A. C. -G. is thankful to Consejería de Economía, Conocimiento, Empresas y Universidad of the Junta de Andalucía (Excellence Research Project P18-RT-1679) and the Oficina de Transferencia de Resultados de Investigación of the University of Granada (PR/17/006 project) for financial support. J. A. M. and H. B. thanks Instituto de Salud Carlos III (RTI2018-101309-B-C22), Fundación Mutua Madrileña (project FMM-AP16683-2017), Consejería de Salud Junta de Andalucía (PI-0089-2017) for financial support.
المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1551-1561 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instnameمصطلحات موضوعية: Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor [Medical Subject Headings], Models, Molecular, Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protein Kinase Inhibitors [Medical Subject Headings], Receptor, ErbB-2, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cysteine Proteases::Cysteine Endopeptidases::Caspases::Caspases, Effector::Caspase 3 [Medical Subject Headings], Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases::Receptor Protein-Tyrosine Kinases::Receptor, erbB-2 [Medical Subject Headings], Cancer cell line, Modelos moleculares, Drug Discovery, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Molecular [Medical Subject Headings], Molecular Structure, pyroptosis, Biochemistry and Molecular Biology, Läkemedelskemi, General Medicine, molecular modelling, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Structure-Activity Relationship [Medical Subject Headings], Benzoxazepines, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cysteine Proteases::Cysteine Endopeptidases::Caspases::Caspases, Initiator::Caspase 1 [Medical Subject Headings], Molecular modelling, Piroptosis, Receptor, Research Article, Research Paper, HER2 receptor, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Drug Screening Assays, Antitumor [Medical Subject Headings], Antineoplastic Agents, RM1-950, benzoxazepines, Structure-Activity Relationship, Phenomena and Processes::Chemical Phenomena::Molecular Structure [Medical Subject Headings], Political science, HER2, Cell Line, Tumor, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Toxicity Tests::Inhibitory Concentration 50 [Medical Subject Headings], Pyroptosis, Humans, Her2 receptor, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Design [Medical Subject Headings], Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation [Medical Subject Headings], Protein Kinase Inhibitors, Antitumour, Cell Proliferation, Pharmacology, Genes erbB-2, Línea celular tumoral, Dose-Response Relationship, Drug, Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Dose-Response Relationship, Drug [Medical Subject Headings], Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents [Medical Subject Headings], Antineoplásicos, Design synthesis, Drug Design, Therapeutics. Pharmacology, Medicinal Chemistry, Drug Screening Assays, Antitumor, Humanities, Biokemi och molekylärbiologi
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المؤلفون: Areejit Samal, Sara Zaldívar-López, Claire Maudet, Ana Eulalio, Miguel Mano, Juan J. Garrido, Carmen Aguilar, Susana P. G. Costa, R.P. Vivek-Ananth
المساهمون: [Aguilar, Carmen] Univ Wurzburg, Inst Mol Infect Biol IMIB, Host RNA Metab Grp, Wurzburg, Germany, [Maudet, Claire] Univ Wurzburg, Inst Mol Infect Biol IMIB, Host RNA Metab Grp, Wurzburg, Germany, [Eulalio, Ana] Univ Wurzburg, Inst Mol Infect Biol IMIB, Host RNA Metab Grp, Wurzburg, Germany, [Costa, Susana] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, RNA & Infect Lab, Coimbra, Portugal, [Eulalio, Ana] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, RNA & Infect Lab, Coimbra, Portugal, [Costa, Susana] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, Funct Genom & RNA Based Therapeut Lab, Coimbra, Portugal, [Mano, Miguel] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, Funct Genom & RNA Based Therapeut Lab, Coimbra, Portugal, [Costa, Susana] Univ Coimbra, Inst Interdisciplinary Res IIIUC, PhD Programme Expt Biol & Biomed PDBEB, Coimbra, Portugal, [Vivek-Ananth, R. P.] Homi Bhabha Natl Inst HBNI, Inst Math Sci IMSc, Chennai, Tamil Nadu, India, [Samal, Areejit] Homi Bhabha Natl Inst HBNI, Inst Math Sci IMSc, Chennai, Tamil Nadu, India, [Zaldivar-Lopez, Sara] Univ Cordoba, Fac Vet Sci, Dept Genet, Anim Breeding & Genom Grp, Cordoba, Spain, [Garrido, Juan J.] Univ Cordoba, Fac Vet Sci, Dept Genet, Anim Breeding & Genom Grp, Cordoba, Spain, [Zaldivar-Lopez, Sara] Maimonides Biomed Res Inst Cordoba IMIBIC, Immunogen & Mol Pathogenesis GA14 Grp, Cordoba, Spain, [Garrido, Juan J.] Maimonides Biomed Res Inst Cordoba IMIBIC, Immunogen & Mol Pathogenesis GA14 Grp, Cordoba, Spain, [Mano, Miguel] Univ Coimbra, Dept Life Sci, Coimbra, Portugal, [Eulalio, Ana] Univ Coimbra, Dept Life Sci, Coimbra, Portugal, [Maudet, Claire] Inst Pasteur, Biol Infect Unit, Paris, France, Bayerischen Gleichstellungsforderung (BGF) through the SCIENTIA Program, Portuguese Foundation for Science and Technology, Bavarian Ministry of Sciences, Research and the Arts, DFG, ERDF - European Regional Development Fund through COMPETE 2020, FCT Investigator Programme, Science and Engineering Research Board (SERB), Department of Science and Technology (DST), India, Ramanujan fellowship, Spanish Ministry of Economy and Competitiveness, [Aguilar,C, Maudet,C, Eulalio,A] Host RNA Metabolism Group, Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany. [Costa,S, Eulalio,A] RNA & Infection Laboratory, Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal. [Costa,S, Mano,M] Functional Genomics and RNA-based Therapeutics Laboratory, Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal. [Costa,S] PhD Programme in Experimental Biology and Biomedicine (PDBEB), Institute for Interdisciplinary Research (IIIUC), University of Coimbra, Coimbra, Portugal. [Vivek-Ananth,RP, Samal,A] The Institute of Mathematical Sciences (IMSc), Homi Bhabha National Institute (HBNI), Chennai, India. [Zaldívar-López,S, Garrido,JJ] Animal Breeding and Genomics Group, Department of Genetics, Faculty of Veterinary Science, University of Córdoba, Córdoba, Spain. [Zaldívar-López,S, Garrido,JJ] Immunogenomics and Molecular Pathogenesis GA14 Group, Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain. [Mano,M, Eulalio,A] Department of Life Sciences, University of Coimbra, Coimbra, Portugal., This work was supported by grants from the Bavarian Ministry of Sciences, Research and the Arts in the framework of the Bavarian Molecular Biosystems Research Network (BioSysNet), DFG project BR 4837/1- 1, ERDF - European Regional Development Fund through COMPETE 2020 and the Portuguese Foundation for Science and Technology (POCI-01-0145-FEDER-007440, UIDB/ 04539/2020, and FCT Investigator Programme IF/01105/2015) to A.E., and the Science and Engineering Research Board (SERB), Department of Science and Technology (DST), India, Ramanujan fellowship (SB/S2/RJN-006/2014) to A.S., and the Spanish Ministry of Economy and Competitiveness (AGL2017-87415-R) to J.J.G.
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: Salmonella typhimurium, 0301 basic medicine, Kinase, Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Shigella::Shigella flexneri [Medical Subject Headings], Swine, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Adaptor Proteins, Signal Transducing::Retinoblastoma Binding Proteins::E2F1 Transcription Factor [Medical Subject Headings], General Physics and Astronomy, Apoptosis, Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Enterobacteriaceae Infections::Salmonella Infections [Medical Subject Headings], Shigella flexneri, 0302 clinical medicine, Salmonella, Endothelial-cells, Bystander effect, E2F1, RNA-Seq, HMGB1 Protein, MicroARNs, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Endoplasmic Reticulum Stress [Medical Subject Headings], Multidisciplinary, Endoplasmic Reticulum Stress, Cell biology, Messenger-rna, 030220 oncology & carcinogenesis, Er stress, Host-Pathogen Interactions, Salmonella Infections, miRNAs, Pathogens, Reprogramming, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Communication::Bystander Effect [Medical Subject Headings], Endoplasmic-reticulum stress, Patógenos, MAP Kinase Signaling System, Science, Infecciones por Salmonella, Activation, Down-Regulation, Protein Serine-Threonine Kinases, Biology, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction::MAP Kinase Signaling System [Medical Subject Headings], Article, General Biochemistry, Genetics and Molecular Biology, Transmembrane protein, 03 medical and health sciences, Downregulation and upregulation, Endoribonucleases, microRNA, Animals, Humans, Secretion, Cellular microbiology, Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Salmonella::Salmonella enterica::Salmonella typhimurium [Medical Subject Headings], Hmgb1, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation [Medical Subject Headings], Endoplasmic reticulum, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Endonucleases::Endoribonucleases [Medical Subject Headings], Bystander Effect, General Chemistry, Bacterial pathogenesis, biology.organism_classification, Listeria monocytogenes, Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases [Medical Subject Headings], Disease Models, Animal, MicroRNAs, 030104 developmental biology, Organisms::Bacteria::Gram-Positive Bacteria::Bacillales::Listeria::Listeria monocytogenes [Medical Subject Headings], Transcription factor, Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::HeLa Cells [Medical Subject Headings], E2F1 Transcription Factor, HeLa Cells
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